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Raul Mostoslavsky, M.D., Ph.D.

Concepts (499)

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Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Sirtuins60202332013.230 Why?
DNA Repair14202220452.100 Why?
Chromatin16202229601.990 Why?
Glycolysis820228361.440 Why?
Histones14202125801.420 Why?
Genomic Instability1020217091.380 Why?
DNA Damage13202224461.220 Why?
Epigenesis, Genetic12202437981.210 Why?
Sirtuin 11720142460.990 Why?
Acetylation18201910550.950 Why?
Chromatin Assembly and Disassembly620216330.950 Why?
Cell Nucleus5202029080.930 Why?
Energy Metabolism6201628810.850 Why?
Glutamine320235770.830 Why?
Acetyl Coenzyme A32017740.820 Why?
Glutathione Transferase120245650.800 Why?
Longevity8201410650.770 Why?
Aging13202387050.760 Why?
DNA Repair Enzymes120213460.680 Why?
Neoplasms142024221640.680 Why?
Cell Transformation, Neoplastic4202228240.660 Why?
Animals9320241684410.660 Why?
Open Reading Frames120218150.620 Why?
DNA Replication4202014180.600 Why?
DNA, Ribosomal120182990.570 Why?
Cytosine220152110.570 Why?
Disease220136720.570 Why?
Hepatocyte Nuclear Factor 3-alpha120171640.560 Why?
RNA Polymerase II220215390.530 Why?
Pancreatic Neoplasms4202453650.510 Why?
Neoplastic Stem Cells2202113470.500 Why?
Mitosis2202111870.500 Why?
Mice642024815090.490 Why?
Embryonic Stem Cells5201812630.490 Why?
Sirtuin 232014950.490 Why?
Histone Deacetylases420137190.480 Why?
Germ-Free Life120141890.470 Why?
Immunoprecipitation320138780.460 Why?
Butyrates120141690.450 Why?
Immunoglobulin kappa-Chains520071690.450 Why?
Chromatin Immunoprecipitation220138550.430 Why?
Proto-Oncogene Proteins3201545100.430 Why?
Cells120141650.420 Why?
Mice, Knockout212021144090.420 Why?
Transcription, Genetic10202175950.420 Why?
Enhancer Elements, Genetic4201713630.410 Why?
Nucleosomes220134870.410 Why?
Immune System420037950.400 Why?
Glucose7201743470.390 Why?
Acetyltransferases120132310.390 Why?
Gene Expression Regulation122018119020.390 Why?
Sirtuin 322011670.390 Why?
Tumor Microenvironment1202438740.370 Why?
Mammals5202311320.370 Why?
Dietary Fiber120147590.360 Why?
Point Mutation1201515960.350 Why?
Gene Expression Regulation, Neoplastic5202485450.340 Why?
Promoter Regions, Genetic4202157890.340 Why?
Hypoxia-Inducible Factor 1, alpha Subunit220106180.330 Why?
DNA Methylation11202443910.320 Why?
Adenosine Triphosphatases120138340.320 Why?
DNA-Binding Proteins4201596060.310 Why?
Alleles8200869220.300 Why?
Chromosomal Proteins, Non-Histone120137270.300 Why?
NAD720236140.300 Why?
Humans8020247614230.290 Why?
Cell Differentiation62018115260.290 Why?
Proto-Oncogene Proteins c-myc420209880.290 Why?
Mitochondria6202336230.290 Why?
Retina2201826580.280 Why?
Cell Proliferation102023104410.280 Why?
RNA-Binding Proteins1201618970.280 Why?
Acetaminophen120115540.280 Why?
Cell Lineage2201625550.280 Why?
Epigenomics120139420.280 Why?
Fungal Proteins120119100.270 Why?
Head and Neck Neoplasms1202128920.270 Why?
Neoplasm Metastasis3202449120.270 Why?
Ovarian Neoplasms1202248760.250 Why?
Gene Rearrangement, B-Lymphocyte, Light Chain32001180.250 Why?
5-Methylcytosine220151480.240 Why?
Drosophila Proteins2201116990.240 Why?
Genes, T-Cell Receptor12004300.240 Why?
SOXB1 Transcription Factors220162860.230 Why?
Mice, Inbred C57BL122024221630.230 Why?
Caenorhabditis elegans Proteins120118740.230 Why?
Adenocarcinoma2202463390.220 Why?
Gene Deletion3202026670.220 Why?
Mice, SCID4202126260.220 Why?
Dioxygenases220153450.210 Why?
Phenotype82017166060.210 Why?
Protein Processing, Post-Translational5201819740.210 Why?
Antibody Specificity1200410600.200 Why?
Glutamates120233890.200 Why?
Nicotinamide Phosphoribosyltransferase32012830.200 Why?
Proline120234570.200 Why?
Glucose Transporter Type 1220141860.200 Why?
B-Lymphocytes7200747640.190 Why?
Nuclear Receptor Subfamily 4, Group A, Member 112021670.190 Why?
Signal Transduction152023234410.190 Why?
Cell Line, Tumor92024169790.190 Why?
Genetic Diseases, Inborn120066050.180 Why?
Fatty Acids3202118080.180 Why?
Metabolism220121930.180 Why?
Immune Evasion120243630.180 Why?
Cell Cycle Proteins5201934470.180 Why?
Heart Diseases1201427850.180 Why?
Genes, Immunoglobulin420062850.180 Why?
Pentose Phosphate Pathway120211260.180 Why?
Pluripotent Stem Cells220187990.180 Why?
Fibronectins120247230.180 Why?
DNA4202472190.180 Why?
NF-E2-Related Factor 2120233730.170 Why?
Scavenger Receptors, Class A12020520.170 Why?
Gene Expression Regulation, Developmental6201536120.170 Why?
Transcription Factors92022121250.170 Why?
Epithelial-Mesenchymal Transition120247360.160 Why?
Insulin4201766020.160 Why?
Lymphocytes2200626110.160 Why?
Down-Regulation5202029180.160 Why?
Kinetics3202163740.160 Why?
Tumor Suppressor Proteins3201628030.160 Why?
Immediate-Early Proteins120214490.160 Why?
Adipocytes, Brown120191500.160 Why?
Glutathione120215820.150 Why?
Lipolysis120192120.150 Why?
PPAR gamma120214840.150 Why?
Transcriptional Elongation Factors120191650.150 Why?
Caloric Restriction320102990.150 Why?
RNA, Neoplasm120217500.150 Why?
Fibroblasts6201741400.150 Why?
Isocitrate Dehydrogenase120249380.150 Why?
Xenograft Model Antitumor Assays3202136020.150 Why?
HMGB Proteins12017450.150 Why?
Mice, 129 Strain220163710.150 Why?
Embryoid Bodies12018650.150 Why?
Lysine320139920.150 Why?
Cell Line72019156050.140 Why?
Dual-Specificity Phosphatases12017710.140 Why?
Gene Knockout Techniques420128020.140 Why?
Gene Expression Regulation, Enzymologic2201211710.130 Why?
Receptors, Notch220117430.130 Why?
Antibodies1200424210.130 Why?
Mutation52024300450.130 Why?
Cell Survival2202457900.130 Why?
Fetal Death120184350.130 Why?
Metabolic Networks and Pathways120207890.130 Why?
High-Throughput Screening Assays120219340.130 Why?
Adenomatous Polyposis Coli Protein120161810.130 Why?
Trans-Activators3201228560.130 Why?
Models, Biological7202094690.130 Why?
Quinazolinones120172210.120 Why?
Diabetes Mellitus1201458400.120 Why?
Reactive Oxygen Species4202321410.120 Why?
Genes, ras220166540.120 Why?
Oxidative Stress6202331100.120 Why?
Colorectal Neoplasms1201469350.120 Why?
Tumor Necrosis Factor-alpha5201643540.120 Why?
High Mobility Group Proteins120151770.120 Why?
Neoplastic Cells, Circulating120219460.120 Why?
Gene Expression3201875840.120 Why?
Cells, Cultured82016189640.120 Why?
Octamer Transcription Factor-3120152230.120 Why?
Eye Proteins120186330.110 Why?
p300-CBP Transcription Factors220121500.110 Why?
Mixed Function Oxygenases120152660.110 Why?
Lipid Metabolism2201419020.110 Why?
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma120173820.110 Why?
Proto-Oncogene Proteins c-akt1202224550.110 Why?
Receptors, Glutamate120142280.110 Why?
Phosphatidylinositol 3-Kinases3202228630.110 Why?
X Chromosome120178160.110 Why?
T-Lymphocytes42017101940.110 Why?
Acrylamides220122590.110 Why?
Catalytic Domain120157050.110 Why?
Circadian Rhythm3201625740.110 Why?
Myocytes, Cardiac2202116680.110 Why?
Antioxidants1202116690.110 Why?
Glucose Intolerance120175750.100 Why?
Intestines1202219090.100 Why?
Oncogene Protein v-akt120121290.100 Why?
Genomic Imprinting320173300.100 Why?
Genome1202017400.100 Why?
Immunoglobulin Heavy Chains220066490.100 Why?
Teratoma120154040.100 Why?
Immunity, Innate1202430610.100 Why?
HEK293 Cells5202142780.100 Why?
S-Adenosylmethionine120132180.100 Why?
Gluconeogenesis120121850.100 Why?
Transfection3201557750.100 Why?
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization120135060.100 Why?
Bone Marrow2202029100.100 Why?
Hepatocytes2202212320.090 Why?
Methyltransferases220133770.090 Why?
Liver5201475320.090 Why?
JNK Mitogen-Activated Protein Kinases120124410.090 Why?
Oxidoreductases, N-Demethylating120111100.090 Why?
Electron Transport120112100.090 Why?
Growth and Development12010470.090 Why?
Sterol Regulatory Element Binding Protein 212010560.090 Why?
Gene Rearrangement, beta-Chain T-Cell Antigen Receptor22008940.090 Why?
Glutamate Dehydrogenase22007500.090 Why?
Citric Acid Cycle120112310.090 Why?
Pro-Opiomelanocortin120101400.090 Why?
Sterol Regulatory Element Binding Protein 1120101350.090 Why?
Recombination, Genetic2200615250.080 Why?
Cardiomegaly120125910.080 Why?
Acetates120113210.080 Why?
Neutrophil Infiltration120123890.080 Why?
Mice, Transgenic8201995350.080 Why?
Isoenzymes1201416880.080 Why?
Single-Cell Analysis1202124490.080 Why?
Adaptation, Physiological1201613010.080 Why?
Cell Respiration120102010.080 Why?
Neoplasm Transplantation1201220160.080 Why?
Molecular Sequence Data42015176440.080 Why?
Genes, T-Cell Receptor beta12008710.080 Why?
Neurogenesis120158620.080 Why?
Neurodegenerative Diseases1201710870.080 Why?
Mice, Inbred BALB C4201662150.080 Why?
RNA Interference2201528310.080 Why?
RecQ Helicases12008530.080 Why?
Base Pair Mismatch12008920.080 Why?
Diabetic Retinopathy1201712740.080 Why?
Silent Information Regulator Proteins, Saccharomyces cerevisiae12007630.070 Why?
Carbon-Carbon Double Bond Isomerases1200750.070 Why?
Gene Silencing3201715090.070 Why?
Enoyl-CoA Hydratase12007110.070 Why?
Acetyl-CoA C-Acyltransferase12007230.070 Why?
Fatty Liver120137890.070 Why?
3-Hydroxyacyl CoA Dehydrogenases12007590.070 Why?
Cluster Analysis1201427060.070 Why?
Gene Rearrangement, B-Lymphocyte120071120.070 Why?
Exodeoxyribonucleases120081920.070 Why?
Somatic Hypermutation, Immunoglobulin120071010.070 Why?
Mitochondria, Liver120071900.070 Why?
Racemases and Epimerases120071140.070 Why?
Immunoglobulin Variable Region320074190.070 Why?
Piperidines2201216560.070 Why?
Mice, Nude1201236140.070 Why?
Amino Acid Sequence22015134490.070 Why?
Stomach Neoplasms1201614590.070 Why?
Liver Neoplasms1202243200.060 Why?
Mitochondria, Muscle120071720.060 Why?
Acylation22018960.060 Why?
Homeodomain Proteins1201524160.060 Why?
Myelin Sheath120096530.060 Why?
Adenoma1201621600.060 Why?
Models, Immunological220065130.060 Why?
Metabolic Diseases120116810.060 Why?
Mice, Inbred NOD2202118270.060 Why?
Environmental Pollutants1201412760.060 Why?
Receptors, Antigen, T-Cell, alpha-beta120088010.060 Why?
Osteogenesis1201112730.060 Why?
Female1320243925810.060 Why?
Nuclear Proteins2201057940.060 Why?
Dendritic Cells1201627460.060 Why?
Insulin-Like Growth Factor I2201219310.060 Why?
S Phase220054210.060 Why?
Hep G2 Cells220173790.060 Why?
Gene Rearrangement, T-Lymphocyte120041110.060 Why?
Transplantation, Heterologous1201223860.060 Why?
Carcinoma, Non-Small-Cell Lung1202353020.060 Why?
Encephalomyelitis, Autoimmune, Experimental120098220.060 Why?
Fasting1201016020.060 Why?
DNA, Mitochondrial220238650.060 Why?
Disease Progression12021135020.060 Why?
Atherosclerosis1202034070.060 Why?
Genotype22016130090.060 Why?
Glycoproteins1201122080.060 Why?
HeLa Cells3201930930.060 Why?
Radiation Tolerance120064790.050 Why?
Autophagy2200913260.050 Why?
Immunoglobulin Light Chains120042860.050 Why?
Genes, Regulator120043740.050 Why?
Induced Pluripotent Stem Cells1201518600.050 Why?
NF-kappa B3201224880.050 Why?
Sequence Homology, Amino Acid1200727480.050 Why?
RNA Editing120041510.050 Why?
Gene Expression Profiling3201494180.050 Why?
Biological Transport2202120920.050 Why?
Glutarates120242430.050 Why?
RNA, Small Interfering4201734280.050 Why?
Nucleoproteins120231130.050 Why?
Apoptosis4201794880.050 Why?
Nucleotidyltransferases120242430.050 Why?
Protein Stability220175780.050 Why?
Somatomedins120221790.050 Why?
Drosophila melanogaster1201117120.050 Why?
Leukopoiesis12001540.050 Why?
Stress, Physiological1200914030.050 Why?
Phenylacetates120211120.050 Why?
Mitochondrial Proteins120079760.050 Why?
CLOCK Proteins22014860.050 Why?
Tumor Escape120243700.050 Why?
ARNTL Transcription Factors22014960.050 Why?
Life Expectancy1200812420.050 Why?
Endothelial Cells2201135410.050 Why?
Globins120014030.050 Why?
Binding Sites3202160550.040 Why?
Hippocampus1201337630.040 Why?
Dosage Compensation, Genetic120012070.040 Why?
Immunohistochemistry12014110730.040 Why?
DNA Transposable Elements120247550.040 Why?
Brain Neoplasms1202290310.040 Why?
Islets of Langerhans1200613460.040 Why?
RNA, Messenger22014127960.040 Why?
Prader-Willi Syndrome12000780.040 Why?
Diabetic Cardiomyopathies12021900.040 Why?
Base Sequence42016124500.040 Why?
Muscular Atrophy120223330.040 Why?
Calcium1201257270.040 Why?
Environmental Exposure1201444670.040 Why?
3' Untranslated Regions120215190.040 Why?
Hematopoiesis2202020490.040 Why?
Insulin-Secreting Cells120069010.040 Why?
Muscle Fibers, Skeletal120225420.040 Why?
Enzyme Activation2201735970.040 Why?
Proto-Oncogene Proteins c-fos120215860.040 Why?
Lymphocyte Activation1200954900.040 Why?
In Situ Hybridization, Fluorescence2200125100.040 Why?
Angelman Syndrome120001400.040 Why?
Receptors, Antigen, B-Cell120015450.040 Why?
Muscle, Skeletal2201149460.040 Why?
Congenital Abnormalities120037090.040 Why?
Cytokines2201273920.040 Why?
Lung Neoplasms12023133370.040 Why?
Bone Density1201135510.040 Why?
Homeostasis3201833210.040 Why?
Gene Rearrangement1200311250.040 Why?
Male1120213607360.040 Why?
Brain52023271070.040 Why?
Cerebral Cortex1201357760.040 Why?
Zebrafish3201730070.030 Why?
Phosphorylation3201783200.030 Why?
Antibody Diversity22007720.030 Why?
Embryonic and Fetal Development119974200.030 Why?
Lipoproteins, LDL120206420.030 Why?
Niacinamide220104130.030 Why?
Tumor Suppressor Protein p532200529160.030 Why?
Lymphoid Enhancer-Binding Factor 112016840.030 Why?
Receptors, CCR7120161070.030 Why?
Electroretinography120185250.030 Why?
MicroRNAs1201138120.030 Why?
Hepatocyte Nuclear Factor 1-alpha120161740.030 Why?
Membrane Transport Proteins1202110350.030 Why?
NIH 3T3 Cells220086710.030 Why?
Gene Knockdown Techniques1202016120.030 Why?
Glycogen Synthase Kinase 3120174110.030 Why?
Homozygote1202017960.030 Why?
Chromosome Mapping1200346380.030 Why?
Mice, Mutant Strains2200817500.030 Why?
Genetic Predisposition to Disease12016179120.030 Why?
Genome, Mitochondrial12014660.030 Why?
Apolipoproteins E1202014430.030 Why?
Breast Neoplasms12021210120.030 Why?
Blastocyst120174330.030 Why?
Tumor Cells, Cultured1202161320.030 Why?
Cell Cycle3201029320.030 Why?
Brain-Derived Neurotrophic Factor120176020.030 Why?
Heart Failure22021116740.030 Why?
Indoles1202118320.030 Why?
Interleukin-12120165830.030 Why?
Neurons2201094620.030 Why?
Glucocorticoids1202221610.030 Why?
CpG Islands1199712290.030 Why?
Animals, Genetically Modified1201715610.030 Why?
Genes, myc120133900.030 Why?
Chemokine CXCL2120121060.030 Why?
Toll-Like Receptors120165890.030 Why?
Organ Specificity1201719670.020 Why?
Sterol Regulatory Element Binding Proteins12011250.020 Why?
Methylation2201010830.020 Why?
Aorta1202020410.020 Why?
Bone Marrow Transplantation1202026950.020 Why?
Saccharomyces cerevisiae1202326870.020 Why?
Hydrolysis120136640.020 Why?
Cholesterol2201129020.020 Why?
Neuroglia120179550.020 Why?
Mice, Obese120124200.020 Why?
Hydrophobic and Hydrophilic Interactions120133980.020 Why?
Histocompatibility Antigens Class II1201614440.020 Why?
Myocardial Infarction12012114580.020 Why?
Diabetes Mellitus, Experimental1201711160.020 Why?
Naphthols12010460.020 Why?
Histone Deacetylase Inhibitors120167740.020 Why?
Blood Glucose2201763910.020 Why?
Retroviridae120128500.020 Why?
Cyclin E120101560.020 Why?
Histone Demethylases120123200.020 Why?
Insulin Receptor Substrate Proteins120115570.020 Why?
Lymphopoiesis120101330.020 Why?
Interleukin-8120126950.020 Why?
Introns120119810.020 Why?
Polymerase Chain Reaction1199860860.020 Why?
Myocardial Reperfusion Injury120124810.020 Why?
Specific Pathogen-Free Organisms120082210.020 Why?
Forkhead Transcription Factors2200716130.020 Why?
ATP-Binding Cassette Transporters120115630.020 Why?
Conserved Sequence1201111650.020 Why?
Crystallography, X-Ray1201319900.020 Why?
Plaque, Atherosclerotic1202015300.020 Why?
AMP-Activated Protein Kinases120115980.020 Why?
Receptor, Notch1120114960.020 Why?
Jurkat Cells120097400.020 Why?
Enzyme Stability120082190.020 Why?
Period Circadian Proteins12008960.020 Why?
Obesity12010129380.020 Why?
Ubiquitin-Activating Enzymes12008850.020 Why?
Poly(ADP-ribose) Polymerases120094260.020 Why?
Yeasts120082790.020 Why?
Starvation120081420.020 Why?
Food Deprivation120071140.020 Why?
Learning1201717400.020 Why?
Early Detection of Cancer1202232010.020 Why?
Adipose Tissue, White120103650.020 Why?
Neovascularization, Pathologic1201726440.020 Why?
Sulfonamides1201719750.020 Why?
Adenosine Diphosphate Ribose12006690.020 Why?
Vascular Endothelial Growth Factor A1201734900.020 Why?
Membrane Potentials1200910900.020 Why?
tau Proteins1201720950.020 Why?
Thymus Neoplasms120082730.020 Why?
Gene Rearrangement, B-Lymphocyte, Heavy Chain12006910.020 Why?
Interleukin-61201632070.020 Why?
Solubility1200710910.020 Why?
Tumor Suppressor Protein p14ARF12005840.020 Why?
Oxidation-Reduction1201122300.020 Why?
Regulatory Sequences, Nucleic Acid220017900.020 Why?
Histone Acetyltransferases120073360.020 Why?
Survival Rate22010127200.020 Why?
Macrophages1202057680.010 Why?
Benzamides1201013700.010 Why?
Antigens, Nuclear120051840.010 Why?
Rad51 Recombinase120051890.010 Why?
Epithelial Cells1201636670.010 Why?
Intercellular Signaling Peptides and Proteins1201116510.010 Why?
Gene Targeting120078380.010 Why?
DNA Breaks, Double-Stranded120086120.010 Why?
Morphogenesis120077410.010 Why?
Adenosine Triphosphate1200919890.010 Why?
Models, Genetic2200634460.010 Why?
Germ-Line Mutation1201118580.010 Why?
Thermogenesis120074750.010 Why?
Microtubule-Associated Proteins1200810760.010 Why?
Embryo, Mammalian1200816750.010 Why?
Dietary Fats1201019940.010 Why?
Basic Helix-Loop-Helix Transcription Factors1200811350.010 Why?
Leptin1201015970.010 Why?
Cyclin-Dependent Kinase Inhibitor p16120056980.010 Why?
Infrared Rays120032470.010 Why?
Locus Control Region12001210.010 Why?
Feedback120067910.010 Why?
Osteoporosis1201116050.010 Why?
Blood Vessels1200711130.010 Why?
Proteasome Endopeptidase Complex1200813200.010 Why?
Disease Models, Animal12021182470.010 Why?
Hydrogen Peroxide120057290.010 Why?
Adipose Tissue, Brown120077640.010 Why?
Reverse Transcriptase Polymerase Chain Reaction1200945750.010 Why?
Enzyme-Linked Immunosorbent Assay1200938100.010 Why?
Proteomics1201538450.010 Why?
Interferon-gamma1200931590.010 Why?
Mice, Inbred CBA120014360.010 Why?
Caenorhabditis elegans1201014560.010 Why?
Adaptor Proteins, Signal Transducing1201128980.010 Why?
Erythroid Precursor Cells120012110.010 Why?
Genetic Markers1200726130.010 Why?
Mesenchymal Stem Cells1201116420.010 Why?
Chromosomes, Human, Pair 11120014100.010 Why?
Cell Movement1201252030.010 Why?
Neovascularization, Physiologic1200713440.010 Why?
Amino Acids1200617180.010 Why?
Lymphoma1200819010.010 Why?
Repressor Proteins1201029850.010 Why?
Lipids1201033400.010 Why?
Antineoplastic Agents12021136370.010 Why?
Doxorubicin1200522240.010 Why?
Transgenes1200110100.010 Why?
Clone Cells1200116590.010 Why?
Fathers120003760.010 Why?
Enzyme Inhibitors1200837120.010 Why?
Transcription Factor RelB11996280.010 Why?
Nuclear Matrix11996300.010 Why?
Immunoglobulin mu-Chains11996620.010 Why?
Cerebellum1200415000.010 Why?
DNA Primers1200028200.010 Why?
Alzheimer Disease1201785960.010 Why?
Feeding Behavior1200731870.010 Why?
Recombinant Proteins1200465320.010 Why?
Intracellular Signaling Peptides and Proteins1200428710.010 Why?
Diabetes Mellitus, Type 212017121430.010 Why?
Pedigree1200045890.010 Why?
Inflammation12012107620.010 Why?
Rats12008237420.010 Why?
Mothers1200021920.010 Why?
Proteins1200460320.000 Why?
Adult120212211480.000 Why?
Time Factors12001399750.000 Why?
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© 2024 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.