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Raul Mostoslavsky, M.D., Ph.D.

Concepts (499)

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Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Sirtuins60202332212.890 Why?
DNA Repair14202220482.060 Why?
Chromatin16202229801.940 Why?
Glycolysis820228381.420 Why?
Histones14202125841.390 Why?
Genomic Instability1020217181.350 Why?
DNA Damage13202224571.200 Why?
Epigenesis, Genetic12202438191.190 Why?
Sirtuin 11720142450.970 Why?
Acetylation18201910530.930 Why?
Chromatin Assembly and Disassembly620216320.930 Why?
Cell Nucleus5202028670.920 Why?
Energy Metabolism6201628920.840 Why?
Glutamine320235760.810 Why?
Acetyl Coenzyme A32017740.800 Why?
Glutathione Transferase120245620.780 Why?
Aging13202387310.750 Why?
Longevity8201410870.750 Why?
DNA Repair Enzymes120213420.670 Why?
Neoplasms142024223400.670 Why?
Cell Transformation, Neoplastic4202228440.650 Why?
Animals9320241687640.650 Why?
Open Reading Frames120218200.600 Why?
DNA Replication4202014330.590 Why?
Disease220136760.550 Why?
Cytosine220152130.550 Why?
DNA, Ribosomal120183000.550 Why?
Hepatocyte Nuclear Factor 3-alpha120171660.550 Why?
RNA Polymerase II220215490.510 Why?
Pancreatic Neoplasms4202454440.500 Why?
Neoplastic Stem Cells2202113520.490 Why?
Mitosis2202111730.490 Why?
Embryonic Stem Cells5201812410.490 Why?
Mice642024818190.480 Why?
Sirtuin 232014930.470 Why?
Histone Deacetylases420137080.470 Why?
Germ-Free Life120141870.460 Why?
Immunoprecipitation320138700.460 Why?
Butyrates120141620.440 Why?
Immunoglobulin kappa-Chains520071720.440 Why?
Chromatin Immunoprecipitation220138570.420 Why?
Proto-Oncogene Proteins3201545200.420 Why?
Cells120141620.420 Why?
Transcription, Genetic10202175990.410 Why?
Mice, Knockout212021144480.410 Why?
Enhancer Elements, Genetic4201713650.410 Why?
Immune System420037990.400 Why?
Nucleosomes220134940.390 Why?
Glucose7201743350.390 Why?
Acetyltransferases120132290.380 Why?
Gene Expression Regulation122018118880.380 Why?
Sirtuin 322011660.380 Why?
Mammals5202311250.360 Why?
Tumor Microenvironment1202439460.360 Why?
Dietary Fiber120147670.350 Why?
Point Mutation1201515900.340 Why?
Gene Expression Regulation, Neoplastic5202486110.330 Why?
Promoter Regions, Genetic4202157860.330 Why?
Hypoxia-Inducible Factor 1, alpha Subunit220106180.320 Why?
DNA Methylation11202444240.320 Why?
Adenosine Triphosphatases120138370.320 Why?
DNA-Binding Proteins4201596010.300 Why?
Alleles8200868970.300 Why?
Chromosomal Proteins, Non-Histone120137220.290 Why?
NAD720236190.290 Why?
Humans8020247659680.290 Why?
Cell Differentiation62018116410.290 Why?
Proto-Oncogene Proteins c-myc420209950.280 Why?
RNA-Binding Proteins1201618740.280 Why?
Retina2201826570.280 Why?
Mitochondria6202336730.280 Why?
Cell Proliferation102023104290.280 Why?
Acetaminophen120115470.280 Why?
Epigenomics120139590.270 Why?
Cell Lineage2201625730.270 Why?
Fungal Proteins120118990.270 Why?
Neoplasm Metastasis3202448930.270 Why?
Head and Neck Neoplasms1202129210.260 Why?
Ovarian Neoplasms1202249000.240 Why?
Gene Rearrangement, B-Lymphocyte, Light Chain32001180.240 Why?
Drosophila Proteins2201116970.230 Why?
5-Methylcytosine220151480.230 Why?
Genes, T-Cell Receptor12004290.230 Why?
SOXB1 Transcription Factors220162820.220 Why?
Mice, Inbred C57BL122024223320.220 Why?
Caenorhabditis elegans Proteins120118840.220 Why?
Adenocarcinoma2202463640.220 Why?
Gene Deletion3202026660.210 Why?
Mice, SCID4202126300.210 Why?
Dioxygenases220153540.200 Why?
Protein Processing, Post-Translational5201819570.200 Why?
Phenotype82017167210.200 Why?
Antibody Specificity1200410610.200 Why?
Glutamates120233840.200 Why?
Nicotinamide Phosphoribosyltransferase32012860.200 Why?
Proline120234530.190 Why?
Glucose Transporter Type 1220141850.190 Why?
B-Lymphocytes7200747780.190 Why?
Nuclear Receptor Subfamily 4, Group A, Member 112021660.190 Why?
Signal Transduction152023236010.190 Why?
Cell Line, Tumor92024170750.190 Why?
Genetic Diseases, Inborn120066050.180 Why?
Fatty Acids3202118060.180 Why?
Cell Cycle Proteins5201934300.180 Why?
Metabolism220121930.180 Why?
Heart Diseases1201428210.180 Why?
Immune Evasion120243770.180 Why?
Genes, Immunoglobulin420062850.180 Why?
DNA4202472020.180 Why?
Pluripotent Stem Cells220188070.180 Why?
Fibronectins120247190.180 Why?
Pentose Phosphate Pathway120211250.170 Why?
NF-E2-Related Factor 2120233850.170 Why?
Scavenger Receptors, Class A12020510.170 Why?
Transcription Factors92022121310.170 Why?
Gene Expression Regulation, Developmental6201536070.170 Why?
Insulin4201765990.160 Why?
Epithelial-Mesenchymal Transition120247520.160 Why?
Lymphocytes2200625990.160 Why?
Down-Regulation5202029270.160 Why?
Kinetics3202162740.160 Why?
Tumor Suppressor Proteins3201627960.160 Why?
Immediate-Early Proteins120214440.150 Why?
Adipocytes, Brown120191600.150 Why?
Glutathione120215880.150 Why?
PPAR gamma120214830.150 Why?
Lipolysis120192110.150 Why?
RNA, Neoplasm120217450.150 Why?
Caloric Restriction320103040.150 Why?
Fibroblasts6201741590.150 Why?
Transcriptional Elongation Factors120191710.150 Why?
Isocitrate Dehydrogenase120249540.150 Why?
Xenograft Model Antitumor Assays3202136080.150 Why?
HMGB Proteins12017450.140 Why?
Mice, 129 Strain220163690.140 Why?
Embryoid Bodies12018640.140 Why?
Lysine320139910.140 Why?
Cell Line72019155430.140 Why?
Dual-Specificity Phosphatases12017710.140 Why?
Gene Knockout Techniques420127980.130 Why?
Gene Expression Regulation, Enzymologic2201211670.130 Why?
Cell Survival2202457470.130 Why?
Receptors, Notch220117520.130 Why?
Antibodies1200424170.130 Why?
Mutation52024301980.130 Why?
Fetal Death120184350.130 Why?
High-Throughput Screening Assays120219380.130 Why?
Metabolic Networks and Pathways120207980.130 Why?
Trans-Activators3201228500.130 Why?
Models, Biological7202094430.130 Why?
Adenomatous Polyposis Coli Protein120161820.120 Why?
Quinazolinones120172190.120 Why?
Diabetes Mellitus1201458910.120 Why?
Reactive Oxygen Species4202321400.120 Why?
Genes, ras220166580.120 Why?
Oxidative Stress6202331410.120 Why?
Colorectal Neoplasms1201469420.120 Why?
Tumor Necrosis Factor-alpha5201643480.120 Why?
Gene Expression3201875840.120 Why?
Neoplastic Cells, Circulating120219500.120 Why?
High Mobility Group Proteins120151800.120 Why?
Cells, Cultured82016189730.110 Why?
Eye Proteins120186280.110 Why?
Octamer Transcription Factor-3120152200.110 Why?
Lipid Metabolism2201418920.110 Why?
p300-CBP Transcription Factors220121470.110 Why?
Mixed Function Oxygenases120152650.110 Why?
Proto-Oncogene Proteins c-akt1202224530.110 Why?
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma120173850.110 Why?
Phosphatidylinositol 3-Kinases3202228780.110 Why?
Receptors, Glutamate120142270.110 Why?
T-Lymphocytes42017102610.110 Why?
X Chromosome120178190.110 Why?
Catalytic Domain120156990.100 Why?
Acrylamides220122570.100 Why?
Circadian Rhythm3201625920.100 Why?
Myocytes, Cardiac2202116680.100 Why?
Antioxidants1202116700.100 Why?
Intestines1202219060.100 Why?
Glucose Intolerance120175800.100 Why?
Oncogene Protein v-akt120121300.100 Why?
Genomic Imprinting320173260.100 Why?
Genome1202017530.100 Why?
Immunoglobulin Heavy Chains220066480.100 Why?
Teratoma120154010.100 Why?
Immunity, Innate1202430810.100 Why?
HEK293 Cells5202142600.100 Why?
S-Adenosylmethionine120132190.090 Why?
Transfection3201557430.090 Why?
Gluconeogenesis120121830.090 Why?
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization120135070.090 Why?
Bone Marrow2202029210.090 Why?
Methyltransferases220133710.090 Why?
Hepatocytes2202212470.090 Why?
Liver5201475620.090 Why?
JNK Mitogen-Activated Protein Kinases120124400.090 Why?
Oxidoreductases, N-Demethylating120111100.090 Why?
Electron Transport120112100.090 Why?
Growth and Development12010460.090 Why?
Sterol Regulatory Element Binding Protein 212010580.090 Why?
Gene Rearrangement, beta-Chain T-Cell Antigen Receptor22008940.090 Why?
Glutamate Dehydrogenase22007500.090 Why?
Citric Acid Cycle120112280.080 Why?
Pro-Opiomelanocortin120101400.080 Why?
Sterol Regulatory Element Binding Protein 1120101350.080 Why?
Recombination, Genetic2200615250.080 Why?
Cardiomegaly120125890.080 Why?
Acetates120113130.080 Why?
Mice, Transgenic8201995500.080 Why?
Isoenzymes1201416890.080 Why?
Neutrophil Infiltration120123940.080 Why?
Single-Cell Analysis1202125350.080 Why?
Adaptation, Physiological1201613080.080 Why?
Cell Respiration120101970.080 Why?
Molecular Sequence Data42015175940.080 Why?
Neoplasm Transplantation1201220140.080 Why?
Neurogenesis120158660.080 Why?
Genes, T-Cell Receptor beta12008700.080 Why?
Neurodegenerative Diseases1201710870.080 Why?
Mice, Inbred BALB C4201662200.080 Why?
RNA Interference2201528320.080 Why?
RecQ Helicases12008540.080 Why?
Base Pair Mismatch12008930.070 Why?
Diabetic Retinopathy1201712990.070 Why?
Silent Information Regulator Proteins, Saccharomyces cerevisiae12007620.070 Why?
Gene Silencing3201715050.070 Why?
Carbon-Carbon Double Bond Isomerases1200750.070 Why?
Enoyl-CoA Hydratase12007110.070 Why?
Acetyl-CoA C-Acyltransferase12007230.070 Why?
Fatty Liver120138070.070 Why?
Cluster Analysis1201427210.070 Why?
3-Hydroxyacyl CoA Dehydrogenases12007590.070 Why?
Gene Rearrangement, B-Lymphocyte120071110.070 Why?
Exodeoxyribonucleases120081910.070 Why?
Somatic Hypermutation, Immunoglobulin120071020.070 Why?
Mitochondria, Liver120071900.070 Why?
Mice, Nude1201236180.070 Why?
Racemases and Epimerases120071130.060 Why?
Piperidines2201216640.060 Why?
Immunoglobulin Variable Region320074190.060 Why?
Amino Acid Sequence22015134000.060 Why?
Stomach Neoplasms1201614710.060 Why?
Liver Neoplasms1202243530.060 Why?
Mitochondria, Muscle120071700.060 Why?
Acylation22018990.060 Why?
Adenoma1201621520.060 Why?
Homeodomain Proteins1201524280.060 Why?
Myelin Sheath120096520.060 Why?
Models, Immunological220065170.060 Why?
Metabolic Diseases120116870.060 Why?
Mice, Inbred NOD2202118370.060 Why?
Environmental Pollutants1201412900.060 Why?
Nuclear Proteins2201057830.060 Why?
Receptors, Antigen, T-Cell, alpha-beta120088130.060 Why?
Osteogenesis1201112820.060 Why?
Female1320243961120.060 Why?
Insulin-Like Growth Factor I2201219360.060 Why?
Dendritic Cells1201627470.060 Why?
S Phase220054240.060 Why?
Hep G2 Cells220173790.060 Why?
Transplantation, Heterologous1201223940.060 Why?
Gene Rearrangement, T-Lymphocyte120041130.060 Why?
Carcinoma, Non-Small-Cell Lung1202353890.060 Why?
Encephalomyelitis, Autoimmune, Experimental120098200.060 Why?
Fasting1201016060.060 Why?
Atherosclerosis1202034240.060 Why?
Genotype22016130240.060 Why?
Glycoproteins1201121950.050 Why?
DNA, Mitochondrial220238690.050 Why?
Disease Progression12021136320.050 Why?
HeLa Cells3201930670.050 Why?
Radiation Tolerance120064750.050 Why?
Autophagy2200913510.050 Why?
Genes, Regulator120043730.050 Why?
NF-kappa B3201224850.050 Why?
Immunoglobulin Light Chains120042900.050 Why?
Induced Pluripotent Stem Cells1201518830.050 Why?
Sequence Homology, Amino Acid1200727450.050 Why?
RNA Editing120041480.050 Why?
Gene Expression Profiling3201495250.050 Why?
Biological Transport2202120810.050 Why?
Nucleoproteins120231100.050 Why?
RNA, Small Interfering4201734210.050 Why?
Glutarates120242430.050 Why?
Apoptosis4201795140.050 Why?
Nucleotidyltransferases120242420.050 Why?
Protein Stability220175770.050 Why?
Somatomedins120221770.050 Why?
Drosophila melanogaster1201117210.050 Why?
Leukopoiesis12001540.050 Why?
Stress, Physiological1200914020.050 Why?
Phenylacetates120211120.050 Why?
Mitochondrial Proteins120079750.050 Why?
CLOCK Proteins22014880.050 Why?
Tumor Escape120243710.050 Why?
Life Expectancy1200812470.050 Why?
ARNTL Transcription Factors22014980.050 Why?
Endothelial Cells2201135840.040 Why?
Binding Sites3202160010.040 Why?
Globins120014060.040 Why?
Hippocampus1201337750.040 Why?
Immunohistochemistry12014110220.040 Why?
Dosage Compensation, Genetic120012090.040 Why?
Brain Neoplasms1202290710.040 Why?
DNA Transposable Elements120247650.040 Why?
RNA, Messenger22014127680.040 Why?
Islets of Langerhans1200613490.040 Why?
Diabetic Cardiomyopathies12021850.040 Why?
Prader-Willi Syndrome12000770.040 Why?
Base Sequence42016124030.040 Why?
Muscular Atrophy120223350.040 Why?
Calcium1201257670.040 Why?
3' Untranslated Regions120215150.040 Why?
Environmental Exposure1201445440.040 Why?
Hematopoiesis2202020580.040 Why?
Insulin-Secreting Cells120068980.040 Why?
Enzyme Activation2201735860.040 Why?
Muscle Fibers, Skeletal120225520.040 Why?
Proto-Oncogene Proteins c-fos120215760.040 Why?
Lymphocyte Activation1200955010.040 Why?
In Situ Hybridization, Fluorescence2200125050.040 Why?
Angelman Syndrome120001390.040 Why?
Bone Density1201134910.040 Why?
Muscle, Skeletal2201149580.040 Why?
Congenital Abnormalities120037040.040 Why?
Receptors, Antigen, B-Cell120015450.040 Why?
Cytokines2201274210.040 Why?
Lung Neoplasms12023134510.040 Why?
Homeostasis3201833360.040 Why?
Gene Rearrangement1200311440.040 Why?
Male1120213636980.040 Why?
Brain52023271710.040 Why?
Cerebral Cortex1201357670.030 Why?
Phosphorylation3201782780.030 Why?
Zebrafish3201730360.030 Why?
Antibody Diversity22007710.030 Why?
Lipoproteins, LDL120206430.030 Why?
Embryonic and Fetal Development119974190.030 Why?
Niacinamide220104190.030 Why?
Tumor Suppressor Protein p532200529420.030 Why?
Lymphoid Enhancer-Binding Factor 112016840.030 Why?
MicroRNAs1201137850.030 Why?
Electroretinography120185260.030 Why?
Receptors, CCR7120161040.030 Why?
Membrane Transport Proteins1202110280.030 Why?
Hepatocyte Nuclear Factor 1-alpha120161750.030 Why?
NIH 3T3 Cells220086510.030 Why?
Gene Knockdown Techniques1202015990.030 Why?
Glycogen Synthase Kinase 3120174140.030 Why?
Homozygote1202017750.030 Why?
Chromosome Mapping1200346180.030 Why?
Mice, Mutant Strains2200817450.030 Why?
Genetic Predisposition to Disease12016180710.030 Why?
Genome, Mitochondrial12014680.030 Why?
Breast Neoplasms12021210560.030 Why?
Apolipoproteins E1202014580.030 Why?
Cell Cycle3201029200.030 Why?
Tumor Cells, Cultured1202161130.030 Why?
Blastocyst120174320.030 Why?
Brain-Derived Neurotrophic Factor120176050.030 Why?
Heart Failure22021118400.030 Why?
Indoles1202118390.030 Why?
Interleukin-12120165790.030 Why?
Glucocorticoids1202221320.030 Why?
Neurons2201095250.030 Why?
CpG Islands1199712070.030 Why?
Animals, Genetically Modified1201715600.030 Why?
Genes, myc120133930.020 Why?
Chemokine CXCL2120121050.020 Why?
Toll-Like Receptors120165830.020 Why?
Organ Specificity1201719650.020 Why?
Methylation2201010730.020 Why?
Sterol Regulatory Element Binding Proteins12011250.020 Why?
Aorta1202020280.020 Why?
Saccharomyces cerevisiae1202326740.020 Why?
Hydrolysis120136420.020 Why?
Cholesterol2201128980.020 Why?
Bone Marrow Transplantation1202027290.020 Why?
Neuroglia120179640.020 Why?
Mice, Obese120124170.020 Why?
Hydrophobic and Hydrophilic Interactions120133900.020 Why?
Histocompatibility Antigens Class II1201614410.020 Why?
Myocardial Infarction12012114990.020 Why?
Diabetes Mellitus, Experimental1201711180.020 Why?
Histone Deacetylase Inhibitors120167770.020 Why?
Naphthols12010450.020 Why?
Blood Glucose2201764240.020 Why?
Retroviridae120128470.020 Why?
Cyclin E120101560.020 Why?
Insulin Receptor Substrate Proteins120115580.020 Why?
Histone Demethylases120123280.020 Why?
Lymphopoiesis120101320.020 Why?
Interleukin-8120127000.020 Why?
Introns120119660.020 Why?
Polymerase Chain Reaction1199860690.020 Why?
Myocardial Reperfusion Injury120124780.020 Why?
Specific Pathogen-Free Organisms120082200.020 Why?
Forkhead Transcription Factors2200716240.020 Why?
Conserved Sequence1201111600.020 Why?
ATP-Binding Cassette Transporters120115680.020 Why?
Crystallography, X-Ray1201319470.020 Why?
Plaque, Atherosclerotic1202015290.020 Why?
AMP-Activated Protein Kinases120115950.020 Why?
Jurkat Cells120097370.020 Why?
Enzyme Stability120082170.020 Why?
Receptor, Notch1120115170.020 Why?
Period Circadian Proteins12008970.020 Why?
Obesity12010130760.020 Why?
Ubiquitin-Activating Enzymes12008840.020 Why?
Poly(ADP-ribose) Polymerases120094290.020 Why?
Yeasts120082780.020 Why?
Learning1201717550.020 Why?
Starvation120081410.020 Why?
Food Deprivation120071140.020 Why?
Early Detection of Cancer1202232360.020 Why?
Neovascularization, Pathologic1201726310.020 Why?
Adipose Tissue, White120103700.020 Why?
Sulfonamides1201719840.020 Why?
Adenosine Diphosphate Ribose12006700.020 Why?
Vascular Endothelial Growth Factor A1201735130.020 Why?
Membrane Potentials1200910830.020 Why?
tau Proteins1201721120.020 Why?
Thymus Neoplasms120082700.020 Why?
Gene Rearrangement, B-Lymphocyte, Heavy Chain12006890.020 Why?
Solubility1200710780.020 Why?
Interleukin-61201632220.020 Why?
Oxidation-Reduction1201122180.020 Why?
Tumor Suppressor Protein p14ARF12005840.020 Why?
Regulatory Sequences, Nucleic Acid220017920.020 Why?
Histone Acetyltransferases120073320.010 Why?
Survival Rate22010127950.010 Why?
Macrophages1202057720.010 Why?
Benzamides1201013770.010 Why?
Antigens, Nuclear120051820.010 Why?
Epithelial Cells1201636810.010 Why?
Intercellular Signaling Peptides and Proteins1201116570.010 Why?
Rad51 Recombinase120051910.010 Why?
Gene Targeting120078410.010 Why?
DNA Breaks, Double-Stranded120086040.010 Why?
Morphogenesis120077440.010 Why?
Models, Genetic2200634490.010 Why?
Adenosine Triphosphate1200919990.010 Why?
Thermogenesis120074960.010 Why?
Germ-Line Mutation1201118840.010 Why?
Microtubule-Associated Proteins1200810660.010 Why?
Embryo, Mammalian1200816730.010 Why?
Dietary Fats1201020020.010 Why?
Basic Helix-Loop-Helix Transcription Factors1200811400.010 Why?
Leptin1201015960.010 Why?
Infrared Rays120032460.010 Why?
Locus Control Region12001210.010 Why?
Cyclin-Dependent Kinase Inhibitor p16120057030.010 Why?
Feedback120067960.010 Why?
Osteoporosis1201115820.010 Why?
Proteasome Endopeptidase Complex1200813140.010 Why?
Blood Vessels1200711130.010 Why?
Disease Models, Animal12021182930.010 Why?
Hydrogen Peroxide120057430.010 Why?
Enzyme-Linked Immunosorbent Assay1200938070.010 Why?
Reverse Transcriptase Polymerase Chain Reaction1200945620.010 Why?
Adipose Tissue, Brown120077760.010 Why?
Proteomics1201539100.010 Why?
Interferon-gamma1200931600.010 Why?
Adaptor Proteins, Signal Transducing1201129000.010 Why?
Mice, Inbred CBA120014390.010 Why?
Caenorhabditis elegans1201014770.010 Why?
Erythroid Precursor Cells120012110.010 Why?
Genetic Markers1200726010.010 Why?
Mesenchymal Stem Cells1201116630.010 Why?
Cell Movement1201251940.010 Why?
Chromosomes, Human, Pair 11120014120.010 Why?
Neovascularization, Physiologic1200713750.010 Why?
Amino Acids1200617090.010 Why?
Lymphoma1200818970.010 Why?
Repressor Proteins1201029680.010 Why?
Lipids1201033150.010 Why?
Antineoplastic Agents12021136480.010 Why?
Doxorubicin1200522300.010 Why?
Transgenes1200110150.010 Why?
Clone Cells1200116720.010 Why?
Fathers120003760.010 Why?
Enzyme Inhibitors1200837150.010 Why?
Transcription Factor RelB11996290.010 Why?
Nuclear Matrix11996300.010 Why?
Immunoglobulin mu-Chains11996620.010 Why?
Cerebellum1200415180.010 Why?
DNA Primers1200028250.010 Why?
Alzheimer Disease1201787300.010 Why?
Feeding Behavior1200732120.010 Why?
Recombinant Proteins1200464930.010 Why?
Intracellular Signaling Peptides and Proteins1200428800.010 Why?
Pedigree1200045260.010 Why?
Diabetes Mellitus, Type 212017122400.010 Why?
Inflammation12012108500.010 Why?
Rats12008237070.010 Why?
Mothers1200022100.010 Why?
Proteins1200459950.000 Why?
Adult120212230440.000 Why?
Time Factors12001400650.000 Why?
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© 2025 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.