"Lipoproteins, LDL" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core composed mainly of CHOLESTEROL ESTERS and smaller amounts of TRIGLYCERIDES. The surface monolayer consists mostly of PHOSPHOLIPIDS, a single copy of APOLIPOPROTEIN B-100, and free cholesterol molecules. The main LDL function is to transport cholesterol and cholesterol esters to extrahepatic tissues.
MeSH Number(s)
D10.532.515
D12.776.521.550
Concept/Terms
Lipoproteins, LDL- Lipoproteins, LDL
- LDL Lipoproteins
- Low-Density Lipoproteins
- Lipoproteins, Low-Density
- Low Density Lipoproteins
- beta-Lipoproteins
- beta Lipoproteins
LDL-1- LDL-1
- LDL1
- Low-Density Lipoprotein 1
- Low Density Lipoprotein 1
- LDL(1)
LDL-2- LDL-2
- LDL2
- Low-Density Lipoprotein 2
- Low Density Lipoprotein 2
- LDL(2)
Below are MeSH descriptors whose meaning is more general than "Lipoproteins, LDL".
Below are MeSH descriptors whose meaning is more specific than "Lipoproteins, LDL".
This graph shows the total number of publications written about "Lipoproteins, LDL" by people in Harvard Catalyst Profiles by year, and whether "Lipoproteins, LDL" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 4 | 4 | 8 |
1995 | 4 | 5 | 9 |
1996 | 6 | 2 | 8 |
1997 | 2 | 5 | 7 |
1998 | 5 | 6 | 11 |
1999 | 1 | 3 | 4 |
2000 | 2 | 2 | 4 |
2001 | 4 | 4 | 8 |
2002 | 9 | 4 | 13 |
2003 | 5 | 5 | 10 |
2004 | 3 | 6 | 9 |
2005 | 6 | 7 | 13 |
2006 | 5 | 12 | 17 |
2007 | 6 | 4 | 10 |
2008 | 3 | 4 | 7 |
2009 | 7 | 5 | 12 |
2010 | 6 | 10 | 16 |
2011 | 10 | 9 | 19 |
2012 | 5 | 8 | 13 |
2013 | 10 | 5 | 15 |
2014 | 6 | 8 | 14 |
2015 | 8 | 6 | 14 |
2016 | 10 | 9 | 19 |
2017 | 5 | 12 | 17 |
2018 | 2 | 11 | 13 |
2019 | 5 | 10 | 15 |
2020 | 4 | 7 | 11 |
2021 | 4 | 7 | 11 |
2022 | 0 | 8 | 8 |
2023 | 0 | 6 | 6 |
2024 | 0 | 2 | 2 |
Below are the most recent publications written about "Lipoproteins, LDL" by people in Profiles.
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Metabolic health's central role in chronic kidney disease progression: a 20-year study of obesity-metabolic phenotype transitions. Sci Rep. 2024 03 04; 14(1):5244.
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Unlocking the mysteries of VLDL: exploring its production, intracellular trafficking, and metabolism as therapeutic targets. Lipids Health Dis. 2024 Jan 12; 23(1):14.
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Food Intake Suppresses ApoB Secretion and Fractional Catabolic Rates in Humans. Arterioscler Thromb Vasc Biol. 2024 02; 44(2):435-451.
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DNA Methylation Near CPT1A and Changes in Triglyceride-rich Lipoproteins in Response to Weight-loss Diet Interventions. J Clin Endocrinol Metab. 2023 Jul 14; 108(8):e542-e549.
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GalNAc-Lipid nanoparticles enable non-LDLR dependent hepatic delivery of a CRISPR base editing therapy. Nat Commun. 2023 05 15; 14(1):2776.
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Normal range CAG repeat size variations in the HTT gene are associated with an adverse lipoprotein profile partially mediated by body mass index. Hum Mol Genet. 2023 05 05; 32(10):1741-1752.
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Multiancestry Genome-Wide Association Study of Aortic Stenosis Identifies Multiple Novel Loci in the Million Veteran Program. Circulation. 2023 03 21; 147(12):942-955.
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The Impact of Reimbursement for Non-Face-to-Face Chronic Care Management on Comprehensive Metabolic Biomarkers Among Multimorbid Patients With Type 2 Diabetes. Med Care. 2023 03 01; 61(3):157-164.
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Mirabegron-induced brown fat activation does not exacerbate atherosclerosis in mice with a functional hepatic ApoE-LDLR pathway. Pharmacol Res. 2023 01; 187:106634.
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Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Promotes Macrophage Activation via LDL Receptor-Independent Mechanisms. Circ Res. 2022 11 11; 131(11):873-889.