Encephalomyelitis, Autoimmune, Experimental
"Encephalomyelitis, Autoimmune, Experimental" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)
MeSH Number(s)
C10.114.703.300
C10.228.140.695.562.250
C10.228.518.562.250
C10.314.350.250
C20.111.258.625.300
E05.598.500.500.500
Concept/Terms
Encephalomyelitis, Autoimmune, Experimental- Encephalomyelitis, Autoimmune, Experimental
- Allergic Encephalomyelitis, Experimental
- Encephalomyelitis, Experimental Allergic
- Experimental Allergic Encephalomyelitides
- Autoimmune Encephalomyelitis, Experimental
- Experimental Autoimmune Encephalomyelitis
- Encephalomyelitis, Allergic
- Encephalomyelitis, Experimental Autoimmune
- Experimental Allergic Encephalomyelitis
- Allergic Encephalomyelitis
- Autoimmune Experimental Encephalomyelitis
- Encephalomyelitis, Autoimmune Experimental
- Experimental Encephalomyelitis, Autoimmune
Below are MeSH descriptors whose meaning is more general than "Encephalomyelitis, Autoimmune, Experimental".
- Diseases [C]
- Nervous System Diseases [C10]
- Autoimmune Diseases of the Nervous System [C10.114]
- Nervous System Autoimmune Disease, Experimental [C10.114.703]
- Encephalomyelitis, Autoimmune, Experimental [C10.114.703.300]
- Central Nervous System Diseases [C10.228]
- Brain Diseases [C10.228.140]
- Leukoencephalopathies [C10.228.140.695]
- Demyelinating Autoimmune Diseases, CNS [C10.228.140.695.562]
- Encephalomyelitis, Autoimmune, Experimental [C10.228.140.695.562.250]
- Leukoencephalopathies [C10.228.518]
- Demyelinating Autoimmune Diseases, CNS [C10.228.518.562]
- Encephalomyelitis, Autoimmune, Experimental [C10.228.518.562.250]
- Demyelinating Diseases [C10.314]
- Demyelinating Autoimmune Diseases, CNS [C10.314.350]
- Encephalomyelitis, Autoimmune, Experimental [C10.314.350.250]
- Immune System Diseases [C20]
- Autoimmune Diseases [C20.111]
- Autoimmune Diseases of the Nervous System [C20.111.258]
- Nervous System Autoimmune Disease, Experimental [C20.111.258.625]
- Encephalomyelitis, Autoimmune, Experimental [C20.111.258.625.300]
- Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
- Investigative Techniques [E05]
- Models, Animal [E05.598]
- Disease Models, Animal [E05.598.500]
- Nervous System Autoimmune Disease, Experimental [E05.598.500.500]
- Encephalomyelitis, Autoimmune, Experimental [E05.598.500.500.500]
Below are MeSH descriptors whose meaning is more specific than "Encephalomyelitis, Autoimmune, Experimental".
This graph shows the total number of publications written about "Encephalomyelitis, Autoimmune, Experimental" by people in Harvard Catalyst Profiles by year, and whether "Encephalomyelitis, Autoimmune, Experimental" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 8 | 1 | 9 |
1995 | 5 | 4 | 9 |
1996 | 11 | 2 | 13 |
1997 | 5 | 1 | 6 |
1998 | 10 | 1 | 11 |
1999 | 9 | 3 | 12 |
2000 | 8 | 4 | 12 |
2001 | 13 | 4 | 17 |
2002 | 4 | 5 | 9 |
2003 | 11 | 5 | 16 |
2004 | 11 | 7 | 18 |
2005 | 9 | 2 | 11 |
2006 | 8 | 2 | 10 |
2007 | 14 | 5 | 19 |
2008 | 13 | 7 | 20 |
2009 | 13 | 1 | 14 |
2010 | 13 | 5 | 18 |
2011 | 11 | 8 | 19 |
2012 | 14 | 1 | 15 |
2013 | 10 | 8 | 18 |
2014 | 14 | 10 | 24 |
2015 | 18 | 7 | 25 |
2016 | 13 | 9 | 22 |
2017 | 6 | 4 | 10 |
2018 | 12 | 3 | 15 |
2019 | 19 | 3 | 22 |
2020 | 8 | 4 | 12 |
2021 | 14 | 7 | 21 |
2022 | 11 | 0 | 11 |
2023 | 13 | 0 | 13 |
2024 | 1 | 0 | 1 |
Below are the most recent publications written about "Encephalomyelitis, Autoimmune, Experimental" by people in Profiles.
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The liver and muscle secreted HFE2-protein maintains central nervous system blood vessel integrity. Nat Commun. 2024 Feb 03; 15(1):1037.
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Thymic Innervation Impairment in Experimental Autoimmune Encephalomyelitis. Neuroimmunomodulation. 2024; 31(1):25-39.
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Cutting Edge: Serpine1 Negatively Regulates Th1 Cell Responses in Experimental Autoimmune Encephalomyelitis. J Immunol. 2023 12 15; 211(12):1762-1766.
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Short-chain fatty acid producers in the gut are associated with pediatric multiple sclerosis onset. Ann Clin Transl Neurol. 2024 01; 11(1):169-184.
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Targeting PGLYRP1 promotes antitumor immunity while inhibiting autoimmune neuroinflammation. Nat Immunol. 2023 Nov; 24(11):1908-1920.
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Metabolic modulation of mitochondrial mass during CD4+ T cell activation. Cell Chem Biol. 2023 09 21; 30(9):1064-1075.e8.
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IFN? and CTLA-4 Drive Hepatic CD4 T-Cell Tolerance and Protection From Autoimmunity in Mice. Cell Mol Gastroenterol Hepatol. 2024; 17(1):79-91.
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Electrophysiological and Histological Correlations of Optic Neuritis in the Dark Agouti Rat Model of Experimental Autoimmune Encephalomyelitis. Neuroscience. 2023 08 01; 524:89-93.
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Constitutive IL-1RA production by modified immune cells protects against IL-1-mediated inflammatory disorders. Sci Transl Med. 2023 05 31; 15(698):eade3856.
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Steady-state memory-phenotype conventional CD4+ T cells exacerbate autoimmune neuroinflammation in a bystander manner via the Bhlhe40/GM-CSF axis. Exp Mol Med. 2023 05; 55(5):1033-1045.