Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced, and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis.
Concept/Terms
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- Mass Spectrometry, Matrix-Assisted Laser Desorption-Ionization
- Mass Spectrometry, Matrix Assisted Laser Desorption Ionization
- Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
- Matrix Assisted Laser Desorption Ionization Mass Spectrometry
- MALDI
- Spectroscopy, Mass, Matrix-Assisted Laser Desorption-Ionization
- MS-MALD
- MALD-MS
- MALDI-MS
- MALDI MS
- Laser Desorption-Ionization Mass Spectrometry, Matrix-Assisted
- Laser Desorption Ionization Mass Spectrometry, Matrix Assisted
- Mass Spectroscopy, Matrix-Assisted Laser Desorption-Ionization
- Mass Spectroscopy, Matrix Assisted Laser Desorption Ionization
Below are MeSH descriptors whose meaning is more general than "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization".
Below are MeSH descriptors whose meaning is more specific than "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization".
This graph shows the total number of publications written about "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" by people in Harvard Catalyst Profiles by year, and whether "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1995 | 2 | 0 | 2 |
1996 | 0 | 9 | 9 |
1997 | 0 | 3 | 3 |
1998 | 0 | 5 | 5 |
1999 | 1 | 3 | 4 |
2000 | 1 | 8 | 9 |
2001 | 1 | 13 | 14 |
2002 | 4 | 15 | 19 |
2003 | 5 | 18 | 23 |
2004 | 1 | 10 | 11 |
2005 | 5 | 24 | 29 |
2006 | 4 | 16 | 20 |
2007 | 4 | 15 | 19 |
2008 | 0 | 24 | 24 |
2009 | 6 | 16 | 22 |
2010 | 5 | 15 | 20 |
2011 | 4 | 15 | 19 |
2012 | 3 | 15 | 18 |
2013 | 11 | 13 | 24 |
2014 | 7 | 11 | 18 |
2015 | 2 | 8 | 10 |
2016 | 5 | 13 | 18 |
2017 | 3 | 3 | 6 |
2018 | 2 | 5 | 7 |
2019 | 2 | 5 | 7 |
2020 | 3 | 2 | 5 |
2021 | 5 | 4 | 9 |
2022 | 0 | 6 | 6 |
2023 | 0 | 5 | 5 |
2024 | 0 | 1 | 1 |
Below are the most recent publications written about "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" by people in Profiles.
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Differential Protease Specificity by Collagenase as a Novel Approach to Serum Proteomics That Includes Identification of Extracellular Matrix Proteins without Enrichment. J Am Soc Mass Spectrom. 2024 Mar 06; 35(3):487-497.
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Relative Quantification of Lipid Isomers in Imaging Mass Spectrometry Using Gas-Phase Charge Inversion Ion/Ion Reactions and Infrared Multiphoton Dissociation. Anal Chem. 2023 12 05; 95(48):17766-17775.
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Chemical QuantArray: A Quantitative Tool for Mass Spectrometry Imaging. Anal Chem. 2023 08 01; 95(30):11243-11253.
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Mass photometry: A powerful tool for carbohydrates-proteins conjugation monitoring and glycoconjugates molecular mass determination. Glycoconj J. 2023 08; 40(4):401-412.
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Mass spectrometry imaging of hair identifies daily maraviroc adherence in HPTN 069/ACTG A5305. PLoS One. 2023; 18(6):e0287449.
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Deep Learning on Multimodal Chemical and Whole Slide Imaging Data for Predicting Prostate Cancer Directly from Tissue Images. J Am Soc Mass Spectrom. 2023 Feb 01; 34(2):227-235.
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Utilizing PET and MALDI Imaging for Discovery of a Targeted Probe for Brain Endocannabinoid a/ß-Hydrolase Domain 6 (ABHD6). J Med Chem. 2023 01 12; 66(1):538-552.
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FcMBL magnetic bead-based MALDI-TOF MS rapidly identifies paediatric blood stream infections from positive blood cultures. PLoS One. 2022; 17(11):e0276777.
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Hidden in plain sight: urinary Cryptococcus neoformans missed by routine diagnostics in a patient with acute leukemia. Ann Clin Microbiol Antimicrob. 2022 Nov 12; 21(1):49.
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Spatially resolved characterization of tissue metabolic compartments in fasted and high-fat diet livers. PLoS One. 2022; 17(9):e0261803.