Conserved Sequence

"Conserved Sequence" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A sequence of amino acids in a polypeptide or of nucleotides in DNA or RNA that is similar across multiple species. A known set of conserved sequences is represented by a CONSENSUS SEQUENCE. AMINO ACID MOTIFS are often composed of conserved sequences.

Descriptor ID

D017124

MeSH Number(s)

G02.111.570.580

Concept/Terms

Conserved Sequence

Below are MeSH descriptors whose meaning is more general than "Conserved Sequence".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Conserved Sequence [G02.111.570.580]

Below are MeSH descriptors whose meaning is related to "Conserved Sequence".

Below are MeSH descriptors whose meaning is more specific than "Conserved Sequence".

Conserved Sequence
Consensus Sequence

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Conserved Sequence" by people in Harvard Catalyst Profiles by year, and whether "Conserved Sequence" was a major or minor topic of these publication.

Bar chart showing 870 publications over 30 distinct years, with a maximum of 52 publications in 2007

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	2	33	35
1995	3	29	32
1996	3	19	22
1997	1	24	25
1998	2	31	33
1999	6	37	43
2000	5	38	43
2001	7	26	33
2002	3	30	33
2003	4	24	28
2004	4	38	42
2005	7	40	47
2006	4	35	39
2007	11	41	52
2008	5	28	33
2009	3	34	37
2010	2	25	27
2011	4	21	25
2012	4	27	31
2013	2	24	26
2014	4	32	36
2015	3	23	26
2016	5	20	25
2017	2	18	20
2018	3	16	19
2019	6	18	24
2020	1	14	15
2021	2	10	12
2022	1	2	3
2023	1	3	4

Below are the most recent publications written about "Conserved Sequence" by people in Profiles.

Conserved and divergent gene regulatory programs of the mammalian neocortex. Nature. 2023 Dec; 624(7991):390-402.

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Sequence-specific targeting of Caenorhabditis elegans C-Ala to the D-loop of tRNAAla. J Biol Chem. 2023 09; 299(9):105149.

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Evolutionary constraint and innovation across hundreds of placental mammals. Science. 2023 04 28; 380(6643):eabn3943.

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The functional and evolutionary impacts of human-specific deletions in conserved elements. Science. 2023 04 28; 380(6643):eabn2253.

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Protein import into peroxisomes occurs through a nuclear pore-like phase. Science. 2022 12 16; 378(6625):eadf3971.

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Two broadly conserved families of polyprenyl-phosphate transporters. Nature. 2023 01; 613(7945):729-734.

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The neutralizing breadth of antibodies targeting diverse conserved epitopes between SARS-CoV and SARS-CoV-2. Proc Natl Acad Sci U S A. 2022 08 23; 119(34):e2204256119.

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Excess membrane binding of monomeric alpha-, beta- and gamma-synuclein is invariably associated with inclusion formation and toxicity. Hum Mol Genet. 2021 11 16; 30(23):2332-2346.

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Insight into ALKBH8-related intellectual developmental disability based on the first pathogenic missense variant. Hum Genet. 2022 Feb; 141(2):209-215.

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Mutation of the conserved Asp-Asp pair impairs the structure, function, and inhibition of CTX-M Class A ß-lactamase. FEBS Lett. 2021 12; 595(24):2981-2994.

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