"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
MeSH Number(s)
D06.472.699.587.200.500.625
D12.644.548.586.200.500.625
Concept/Terms
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in Harvard Catalyst Profiles by year, and whether "Insulin" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 32 | 33 | 65 |
| 1995 | 29 | 32 | 61 |
| 1996 | 41 | 22 | 63 |
| 1997 | 39 | 40 | 79 |
| 1998 | 25 | 40 | 65 |
| 1999 | 49 | 41 | 90 |
| 2000 | 36 | 59 | 95 |
| 2001 | 46 | 54 | 100 |
| 2002 | 54 | 64 | 118 |
| 2003 | 52 | 69 | 121 |
| 2004 | 44 | 76 | 120 |
| 2005 | 45 | 62 | 107 |
| 2006 | 55 | 70 | 125 |
| 2007 | 49 | 91 | 140 |
| 2008 | 59 | 99 | 158 |
| 2009 | 56 | 91 | 147 |
| 2010 | 70 | 81 | 151 |
| 2011 | 52 | 82 | 134 |
| 2012 | 78 | 75 | 153 |
| 2013 | 67 | 79 | 146 |
| 2014 | 73 | 79 | 152 |
| 2015 | 55 | 81 | 136 |
| 2016 | 64 | 81 | 145 |
| 2017 | 51 | 71 | 122 |
| 2018 | 44 | 53 | 97 |
| 2019 | 59 | 80 | 139 |
| 2020 | 40 | 59 | 99 |
| 2021 | 41 | 81 | 122 |
| 2022 | 17 | 100 | 117 |
| 2023 | 19 | 77 | 96 |
| 2024 | 1 | 15 | 16 |
Below are the most recent publications written about "Insulin" by people in Profiles.
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Case 10-2024: A 46-Year-Old Woman with Hyperglycemia Refractory to Insulin Therapy. N Engl J Med. 2024 Apr 04; 390(13):1219-1229.
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The Use of Rescue Insulin in the Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness Study (GRADE). Diabetes Care. 2024 Apr 01; 47(4):638-645.
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Diabetes Management in Detention Facilities: A Statement of the American Diabetes Association. Diabetes Care. 2024 04 01; 47(4):544-555.
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Effectiveness of metformin for the reversal of cold-ischemia-induced damage in hepatosteatosis. Clin Res Hepatol Gastroenterol. 2024 Apr; 48(4):102314.
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Out-of-pocket costs for diabetes medications in employer-sponsored health insurance plans. Am J Manag Care. 2024 Mar; 30(3):107-108.
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Critical Evaluation of Indices Used to Assess ß-Cell Function. Diabetes. 2024 Mar 01; 73(3):391-400.
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Pharmacotherapy causing weight gain and metabolic alteration in those with obesity and obesity-related conditions: A review. Ann N Y Acad Sci. 2024 Mar; 1533(1):145-155.
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Metabolomic and genetic architecture of gestational diabetes subtypes. Diabetologia. 2024 May; 67(5):895-907.
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Therapeutic inertia in treatment of older adults with type II diabetes at high risk for hypoglycemia. Prim Care Diabetes. 2024 Apr; 18(2):238-240.
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Ambient Heat and Risk of Serious Hypoglycemia in Older Adults With Diabetes Using Insulin in the U.S. and Taiwan: A Cross-National Case-Crossover Study. Diabetes Care. 2024 Feb 01; 47(2):233-238.