"Insulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
MeSH Number(s)
D06.472.699.587.200.500.625
D12.644.548.586.200.500.625
Concept/Terms
Insulin- Insulin
- Insulin, Regular
- Regular Insulin
- Soluble Insulin
- Insulin, Soluble
Below are MeSH descriptors whose meaning is more general than "Insulin".
Below are MeSH descriptors whose meaning is more specific than "Insulin".
This graph shows the total number of publications written about "Insulin" by people in Harvard Catalyst Profiles by year, and whether "Insulin" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
1994 | 32 | 33 | 65 |
1995 | 29 | 32 | 61 |
1996 | 41 | 22 | 63 |
1997 | 39 | 40 | 79 |
1998 | 25 | 40 | 65 |
1999 | 49 | 41 | 90 |
2000 | 36 | 59 | 95 |
2001 | 46 | 54 | 100 |
2002 | 54 | 64 | 118 |
2003 | 52 | 70 | 122 |
2004 | 44 | 76 | 120 |
2005 | 45 | 62 | 107 |
2006 | 55 | 70 | 125 |
2007 | 49 | 91 | 140 |
2008 | 59 | 99 | 158 |
2009 | 56 | 91 | 147 |
2010 | 70 | 82 | 152 |
2011 | 52 | 83 | 135 |
2012 | 78 | 75 | 153 |
2013 | 67 | 79 | 146 |
2014 | 73 | 79 | 152 |
2015 | 55 | 81 | 136 |
2016 | 64 | 81 | 145 |
2017 | 51 | 71 | 122 |
2018 | 44 | 53 | 97 |
2019 | 59 | 80 | 139 |
2020 | 40 | 60 | 100 |
2021 | 41 | 81 | 122 |
2022 | 18 | 101 | 119 |
2023 | 18 | 77 | 95 |
2024 | 0 | 8 | 8 |
Below are the most recent publications written about "Insulin" by people in Profiles.
-
Critical Evaluation of Indices Used to Assess ß-Cell Function. Diabetes. 2024 Mar 01; 73(3):391-400.
-
Out-of-pocket costs for diabetes medications in employer-sponsored health insurance plans. Am J Manag Care. 2024 Mar; 30(3):107-108.
-
Pharmacotherapy causing weight gain and metabolic alteration in those with obesity and obesity-related conditions: A review. Ann N Y Acad Sci. 2024 Mar; 1533(1):145-155.
-
Ambient Heat and Risk of Serious Hypoglycemia in Older Adults With Diabetes Using Insulin in the U.S. and Taiwan: A Cross-National Case-Crossover Study. Diabetes Care. 2024 Feb 01; 47(2):233-238.
-
Safety of GLP-1 Receptor Agonists and Other Second-Line Antidiabetics in Early Pregnancy. JAMA Intern Med. 2024 Feb 01; 184(2):144-152.
-
Interactions among insulin resistance, epigenetics, and donor sex in gene expression regulation of iPSC-derived myoblasts. J Clin Invest. 2024 Jan 16; 134(2).
-
Randomized Trial of the Insulin-Only iLet Bionic Pancreas for the Treatment of Cystic Fibrosis- Related Diabetes. Diabetes Care. 2024 Jan 01; 47(1):101-108.
-
Free radical scavenging polyphenols isolated from Phyllanthus niruri L. ameliorates hyperglycemia via SIRT1 induction and GLUT4 translocation in in vitro and in vivo models. Fitoterapia. 2024 Mar; 173:105803.
-
Insulin feedback is a targetable resistance mechanism of PI3K inhibition in glioblastoma. Neuro Oncol. 2023 12 08; 25(12):2165-2176.
-
Lack of vitamin D signalling shifts skeletal muscles towards oxidative metabolism. J Cachexia Sarcopenia Muscle. 2024 Feb; 15(1):67-80.