Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Pasi Antero Janne, M.D.,Ph.D.

Concepts (484)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Carcinoma, Non-Small-Cell Lung60202354323.820 Why?
Lung Neoplasms802024135863.350 Why?
Quinazolines25201213732.500 Why?
Protein Kinase Inhibitors36202457042.290 Why?
Receptor, erbB-3720211421.940 Why?
Exons11202223941.770 Why?
Antineoplastic Agents392022136771.610 Why?
Mesothelioma1320088111.360 Why?
Drug Resistance, Neoplasm19202153411.330 Why?
Proto-Oncogene Proteins p21(ras)14202317671.220 Why?
Proto-Oncogene Proteins c-met920245641.200 Why?
Pleural Neoplasms920086121.170 Why?
Aniline Compounds4202310941.090 Why?
Mutation412023302371.010 Why?
Receptor, erbB-27202226030.950 Why?
Genes, ras720216630.900 Why?
Antineoplastic Combined Chemotherapy Protocols212020118780.800 Why?
Mutagenesis, Insertional320226610.780 Why?
Cell Line, Tumor382024171420.750 Why?
Gene Amplification6202010950.750 Why?
Benzeneacetamides12019360.650 Why?
Guanine520082800.610 Why?
Glutamates520083850.610 Why?
Acrylamides220202610.610 Why?
Indoles3202118360.590 Why?
Camptothecin120216000.590 Why?
Oncogenes3202112340.570 Why?
Drug Screening Assays, Antitumor120187190.520 Why?
Pyrimidines8202330480.510 Why?
Adenocarcinoma9201663950.500 Why?
High-Throughput Nucleotide Sequencing6202136700.490 Why?
Thiazoles3201915420.450 Why?
Immunoconjugates120219750.440 Why?
Proto-Oncogene Proteins11202045280.430 Why?
High-Throughput Screening Assays220189420.430 Why?
Xenograft Model Antitumor Assays7202036120.420 Why?
Enzyme Inhibitors7202337280.380 Why?
T-Lymphocytes, Cytotoxic1201818010.370 Why?
Maximum Tolerated Dose620218990.370 Why?
ras Proteins5202010580.370 Why?
Adenocarcinoma, Bronchiolo-Alveolar22007890.340 Why?
MAP Kinase Kinase 1220123310.340 Why?
Carboplatin220127970.330 Why?
Taxoids120126670.320 Why?
MAP Kinase Signaling System6202014950.320 Why?
Mutation, Missense5202325920.320 Why?
Humans12320247681710.310 Why?
Heptanoic Acids120113440.310 Why?
Cisplatin5200616600.310 Why?
Oncogene Proteins v-erbB12007170.300 Why?
Benzimidazoles220138640.300 Why?
Sulfones320184480.300 Why?
Apoptosis11202195270.300 Why?
MAP Kinase Kinase 212007930.280 Why?
Mice252024820490.280 Why?
Proto-Oncogene Proteins c-ret220202280.280 Why?
Morpholines220075840.280 Why?
Disease-Free Survival8202168470.270 Why?
Phosphatidylinositol 3-Kinases8201828850.270 Why?
Oncogene Proteins, Fusion4202016130.270 Why?
Pyrazoles4202020280.270 Why?
Receptors, Growth Factor120073240.260 Why?
Gene Expression Regulation, Neoplastic9202086480.260 Why?
Quinazolinones120072190.260 Why?
DNA, Neoplasm7201817440.260 Why?
Quinolines420207720.250 Why?
Pyridazines220202030.250 Why?
Point Mutation3202415960.250 Why?
Signal Transduction152019236480.240 Why?
Deoxyribonuclease I120062280.240 Why?
In Situ Hybridization, Fluorescence5201825210.240 Why?
Animals3220241692850.240 Why?
Proto-Oncogene Proteins c-akt10201324590.230 Why?
Mitogen-Activated Protein Kinases3201212460.230 Why?
Treatment Outcome242021653790.230 Why?
DNA Mutational Analysis8201941200.220 Why?
Benzamides5202013790.220 Why?
Phosphorylation11201283160.220 Why?
Dose-Response Relationship, Drug72021107630.220 Why?
Survival Analysis122008100990.210 Why?
Aged, 80 and over242021596260.210 Why?
Loss of Heterozygosity220046630.200 Why?
raf Kinases220201170.200 Why?
Carcinoid Tumor120042250.200 Why?
Aged4120211715020.200 Why?
Middle Aged4420212234870.200 Why?
Protein-Tyrosine Kinases7202024330.190 Why?
Disease Models, Animal92021183490.190 Why?
Cell Proliferation102020104780.190 Why?
Receptor Protein-Tyrosine Kinases4201316280.190 Why?
Tumor Cells, Cultured4202061240.190 Why?
Imidazoles2202011690.190 Why?
Female5220233971870.180 Why?
NIH 3T3 Cells320196690.180 Why?
Food-Drug Interactions12020260.180 Why?
Proto-Oncogene Proteins B-raf3201820590.180 Why?
ras-GRF112020260.180 Why?
Amino Acid Substitution4201717430.170 Why?
Cell Transformation, Neoplastic3201128460.170 Why?
Drug Synergism4201917600.170 Why?
Receptor, Fibroblast Growth Factor, Type 2120212130.170 Why?
Mice, Transgenic6201995610.170 Why?
Acetonitriles12019550.170 Why?
Antibodies, Bispecific120222040.160 Why?
Male4820213647310.160 Why?
Receptors, CXCR12019520.160 Why?
Antibodies, Monoclonal6201792620.160 Why?
Luciferases, Firefly12018370.160 Why?
Adaptor Proteins, Signal Transducing3200729090.160 Why?
Pyridines4202028940.160 Why?
Adult3720212236460.160 Why?
Peritoneal Neoplasms120057140.160 Why?
Receptors, Fibroblast Growth Factor120191960.160 Why?
Mice, Inbred NOD2202018370.150 Why?
Genomics8202359260.150 Why?
Neoplasm Metastasis4202149130.150 Why?
Spheroids, Cellular120203310.150 Why?
Mice, SCID2202026270.150 Why?
Allosteric Regulation120194260.150 Why?
Pyrrolidines120193410.140 Why?
Meningeal Neoplasms1200612530.140 Why?
Epidermal Growth Factor320056970.140 Why?
Personality120005590.140 Why?
Disease Progression92017136680.140 Why?
Infusions, Intravenous1202122300.140 Why?
Oligonucleotide Array Sequence Analysis2200738060.130 Why?
Drug Administration Schedule5200848610.130 Why?
Janus Kinase 2220185610.130 Why?
Alleles2200668940.130 Why?
TOR Serine-Threonine Kinases5202320620.130 Why?
DNA Copy Number Variations2201820480.130 Why?
Small Cell Lung Carcinoma120214540.130 Why?
Smoking2201290920.130 Why?
Molecular Conformation120175400.130 Why?
Cholangiocarcinoma120215610.120 Why?
Mitogen-Activated Protein Kinase 3320074740.120 Why?
Bile Duct Neoplasms120216140.120 Why?
Codon120175990.120 Why?
Membrane Proteins3202278760.120 Why?
Killer Cells, Natural2202222110.120 Why?
Janus Kinase 312015760.120 Why?
Neoplasms92020223710.120 Why?
Pyrrolidinones120151160.120 Why?
Piperazines2201925540.120 Why?
Coculture Techniques1201813440.120 Why?
Gene Dosage3201012190.110 Why?
Cell Cycle4201329340.110 Why?
Iodine Radioisotopes1201810340.110 Why?
Cell Culture Techniques1202116670.110 Why?
Prognosis102023300090.110 Why?
Carcinoma, Neuroendocrine120183420.110 Why?
Receptor, Fibroblast Growth Factor, Type 3120141090.110 Why?
Gene Knockout Techniques120178060.110 Why?
Polymorphism, Single Nucleotide42016160440.110 Why?
Nucleoside-Phosphate Kinase12013240.110 Why?
Neoplasm Staging62020112440.110 Why?
Epithelial-Mesenchymal Transition220197570.110 Why?
Immunity1201910030.110 Why?
Clinical Trials as Topic6201680520.110 Why?
Cell Survival3201957890.100 Why?
Internal-External Control320033480.100 Why?
Carcinoma, Small Cell220054190.100 Why?
Immunotherapy, Adoptive1202215120.100 Why?
RNA Interference4201328320.100 Why?
Molecular Targeted Therapy6202128300.100 Why?
ran GTP-Binding Protein12011530.100 Why?
Mice, Nude4201936230.100 Why?
Evidence-Based Practice120165000.100 Why?
Receptors, Mitogen12011610.090 Why?
Tumor Suppressor Proteins2201328100.090 Why?
Oncogene Proteins120157170.090 Why?
Naphthyridines120131850.090 Why?
Phenylurea Compounds120145310.090 Why?
Adaptive Immunity120167330.090 Why?
src-Family Kinases220115390.090 Why?
Protein Structure, Tertiary3200637720.090 Why?
Tumor Escape120133720.090 Why?
Placebos2201216670.080 Why?
Cell Differentiation12007116770.080 Why?
Transfection3200657560.080 Why?
Enzyme Activation3201535900.080 Why?
Sequence Analysis120102400.080 Why?
Genome, Human3201644460.080 Why?
Butadienes220071070.080 Why?
Colorectal Neoplasms2200769750.080 Why?
Combined Modality Therapy6200785420.080 Why?
Genotype42018130450.080 Why?
Hematopoiesis1201820590.080 Why?
Models, Molecular2201754020.080 Why?
Clinical Trials, Phase I as Topic220203300.080 Why?
AMP-Activated Protein Kinases220135970.080 Why?
Antigens, Neoplasm1201619960.080 Why?
Extracellular Signal-Regulated MAP Kinases220126150.080 Why?
Genes, p53220077140.070 Why?
Mutant Proteins120104880.070 Why?
Folic Acid Antagonists12008740.070 Why?
Receptor, Platelet-Derived Growth Factor alpha120103680.070 Why?
Fusion Proteins, bcr-abl120104300.070 Why?
Cell Division2200744770.070 Why?
Mutagenesis, Site-Directed2201416830.070 Why?
Tumor Suppressor Protein p531201829560.070 Why?
CHO Cells2200713790.070 Why?
Protein Binding2201793430.070 Why?
Gene Expression2201776010.070 Why?
Genes, p16120071590.070 Why?
Treatment Failure4200726610.070 Why?
Bronchial Neoplasms120071100.070 Why?
Chromosome Mapping2200646200.070 Why?
Neoplasm Recurrence, Local2202094190.070 Why?
Sequence Analysis, DNA2201647860.070 Why?
Adenosine Triphosphate1201320040.070 Why?
Mosaicism120104800.070 Why?
Immunohistochemistry52018110950.070 Why?
Chromatography, High Pressure Liquid2201015350.070 Why?
Cricetinae2200724230.070 Why?
Proto-Oncogene Proteins c-kit120107250.060 Why?
Stress, Psychological2200345300.060 Why?
Sirolimus3201215400.060 Why?
Nuclear Proteins2202358040.060 Why?
Radiation Pneumonitis120061000.060 Why?
Genes, Neoplasm120073710.060 Why?
Liver Failure, Acute120071820.060 Why?
Proto-Oncogene Proteins c-bcl-23202314060.060 Why?
Chromones120051480.060 Why?
Survival120051600.060 Why?
Transforming Growth Factor alpha120051340.060 Why?
Cricetulus120078120.060 Why?
Doxycycline120073490.060 Why?
Cell Growth Processes120053810.060 Why?
Inhibitory Concentration 50120054660.060 Why?
Paraffin Embedding120063060.060 Why?
Sequence Deletion2200614970.060 Why?
CD8-Positive T-Lymphocytes1201846480.060 Why?
Thrombocythemia, Essential120061140.060 Why?
Class I Phosphatidylinositol 3-Kinases320189050.060 Why?
Pleura120062480.060 Why?
Cell Shape120053710.060 Why?
Colonic Neoplasms1201625410.060 Why?
Polycythemia Vera120061600.060 Why?
Interleukin-3120054250.060 Why?
Formaldehyde120063610.060 Why?
Thyroid Neoplasms1201823600.060 Why?
Antimetabolites, Antineoplastic120086460.060 Why?
Hepatocyte Growth Factor120052680.060 Why?
Polymerase Chain Reaction3201060820.060 Why?
Head and Neck Neoplasms1201829310.060 Why?
Cell Cycle Proteins2201334450.060 Why?
Nitriles220079800.050 Why?
Medical Oncology3201123460.050 Why?
Finland120056090.050 Why?
Genes, erbB-1120041630.050 Why?
Eukaryotic Initiation Factor-4F12023410.050 Why?
Deoxycytidine120088870.050 Why?
Pneumonectomy2200711560.050 Why?
Follow-Up Studies52020393540.050 Why?
Genes, Tumor Suppressor1200710620.050 Why?
Protein-Arginine N-Methyltransferases120231290.050 Why?
Administration, Oral3200740340.050 Why?
Exanthema120075030.050 Why?
Survival Rate22007128400.050 Why?
Nucleic Acid Hybridization1200413050.050 Why?
Hyperthermia, Induced120064160.050 Why?
Mice, Inbred C57BL22018223800.050 Why?
Cloning, Molecular1200741680.050 Why?
Models, Biological1201894970.050 Why?
Tuberous Sclerosis1201010420.050 Why?
Microsatellite Repeats120047850.050 Why?
Sensitivity and Specificity42019147290.050 Why?
Antibiotics, Antineoplastic120056810.050 Why?
Biopsy, Needle1200616230.050 Why?
Prospective Studies72019549240.050 Why?
Tomography, X-Ray Computed42018207620.050 Why?
Blotting, Western2200750280.050 Why?
Diarrhea1200713200.040 Why?
Depression1200082300.040 Why?
Biomedical Research1201634630.040 Why?
Gene Expression Profiling3201695400.040 Why?
Remission Induction1200624100.040 Why?
NF-E2-Related Factor 2120233810.040 Why?
Carcinoma1201123320.040 Why?
Radiotherapy, Intensity-Modulated120067980.040 Why?
Terminal Care1201117700.040 Why?
Receptor, trkA120201590.040 Why?
Tumor Burden2201719060.040 Why?
Radiotherapy, Adjuvant3201117910.040 Why?
Medical History Taking120037790.040 Why?
Tumor Microenvironment3201939480.040 Why?
Neoplasms, Experimental2201912300.040 Why?
Chromosome Aberrations1200517780.040 Why?
Base Sequence22006124220.040 Why?
Cytokines1201374520.040 Why?
Databases, Genetic2201617580.040 Why?
HEK293 Cells2202042800.040 Why?
Communication2200339050.040 Why?
Neovascularization, Pathologic1200826310.040 Why?
Gene Knockdown Techniques2201316060.040 Why?
Genetic Markers1200426030.040 Why?
DNA Helicases120238540.040 Why?
Antibodies1200524210.040 Why?
Confidence Intervals3200729230.040 Why?
Quinoxalines120192970.040 Why?
Patient Selection2200742600.030 Why?
Cluster Analysis1200427320.030 Why?
T-Lymphocytes22013102660.030 Why?
Drug Delivery Systems1200822370.030 Why?
National Human Genome Research Institute (U.S.)12016220.030 Why?
Tissue Distribution1202023000.030 Why?
Quality of Life22011134900.030 Why?
Software2201644800.030 Why?
Education, Medical, Continuing120018290.030 Why?
Drug Therapy, Combination1200663160.030 Why?
Genome1200417540.030 Why?
Multiprotein Complexes2201211100.030 Why?
DNA-Binding Proteins1201396170.030 Why?
Predictive Value of Tests32007154530.030 Why?
Young Adult52021600660.030 Why?
Cell Movement2200552130.030 Why?
MAP Kinase Kinase Kinases120162520.030 Why?
Population Groups120162090.030 Why?
Germ-Line Mutation2201618850.030 Why?
Immunophenotyping1201918640.030 Why?
Analgesia, Patient-Controlled119951170.030 Why?
Lung22019101010.030 Why?
Kaplan-Meier Estimate2201765250.030 Why?
Retrospective Studies62018817600.030 Why?
Risk Assessment22006243180.030 Why?
False Positive Reactions120169630.030 Why?
Forecasting1200329450.030 Why?
Thymine Nucleotides12013570.030 Why?
Algorithms12014141640.030 Why?
Lymphocytes, Tumor-Infiltrating1201911050.030 Why?
Genetic Heterogeneity120167360.030 Why?
Okadaic Acid12012670.030 Why?
Depressive Disorder2199537210.030 Why?
Receptors, Virus120166510.030 Why?
Gene Rearrangement1201711460.020 Why?
Binding, Competitive1201311420.020 Why?
Furans120122020.020 Why?
T-Lymphocyte Subsets1201918160.020 Why?
Fluoxetine119957330.020 Why?
Palliative Care1200636430.020 Why?
Inhibitor of Apoptosis Proteins120122000.020 Why?
Sulfonamides1202019820.020 Why?
Health Status1200440910.020 Why?
HSP90 Heat-Shock Proteins120134230.020 Why?
Breast Neoplasms22011212070.020 Why?
Phosphoprotein Phosphatases120123270.020 Why?
Chemotherapy, Adjuvant2201135560.020 Why?
Mice, Inbred BALB C1201962310.020 Why?
Morphine119956580.020 Why?
STAT1 Transcription Factor120123430.020 Why?
International Cooperation1201714360.020 Why?
Social Support1200021930.020 Why?
Active Transport, Cell Nucleus120114320.020 Why?
Receptors, Antigen, T-Cell1201925680.020 Why?
Sex Factors12004106320.020 Why?
Age Factors12007184150.020 Why?
Western World12009270.020 Why?
Feedback, Physiological120124820.020 Why?
Osteopontin120113110.020 Why?
Feasibility Studies1202053150.020 Why?
Adaptation, Psychological1200026630.020 Why?
Threonine120102730.020 Why?
Research Design1200562090.020 Why?
Attitude of Health Personnel1200339290.020 Why?
Cytogenetic Analysis120092710.020 Why?
Pedigree1201645390.020 Why?
Statistics, Nonparametric1201428620.020 Why?
Physician-Patient Relations1200132690.020 Why?
bcl-X Protein120104120.020 Why?
Positron-Emission Tomography2201566690.020 Why?
Cell Death1201316800.020 Why?
Anthracenes12007830.020 Why?
Nucleic Acid Denaturation120071110.020 Why?
Proteins2201260090.020 Why?
Pilot Projects1202087410.020 Why?
Multigene Family1201010810.020 Why?
Cell Line22013156020.020 Why?
Apoptosis Regulatory Proteins1201211510.020 Why?
Tablets120061490.020 Why?
In Situ Nick-End Labeling120076110.020 Why?
Shc Signaling Adaptor Proteins12005460.020 Why?
DNA Replication1201314270.020 Why?
Attitude to Health1199520250.020 Why?
Tumor Stem Cell Assay120051160.020 Why?
PTEN Phosphohydrolase1201111200.020 Why?
JNK Mitogen-Activated Protein Kinases120074400.020 Why?
Coronary Artery Bypass1199521910.020 Why?
Molecular Structure1201018840.020 Why?
Italy120078560.020 Why?
Time Factors22005402200.020 Why?
Secondary Prevention1201114740.020 Why?
Kinetics1201363300.020 Why?
Electrophoresis, Polyacrylamide Gel1200717300.020 Why?
Immunoprecipitation120078740.020 Why?
Autophagy1201313510.010 Why?
Physicians1200345980.010 Why?
Hospice Care120116780.010 Why?
Drug Approval120118210.010 Why?
Endonucleases120073710.010 Why?
Protein Processing, Post-Translational1201219660.010 Why?
Genetics, Population120099440.010 Why?
Pain, Postoperative1199517650.010 Why?
p38 Mitogen-Activated Protein Kinases120076930.010 Why?
Radiography1201569860.010 Why?
Primary Prevention1201111880.010 Why?
Educational Status1201125150.010 Why?
Gene Deletion1201126740.010 Why?
Metabolomics1201316740.010 Why?
Brain Neoplasms1200591180.010 Why?
Electronic Health Records1202148870.010 Why?
Neoplasm Invasiveness1201136200.010 Why?
Transcription Factors12023121710.010 Why?
Controlled Clinical Trials as Topic120041870.010 Why?
Up-Regulation1201241490.010 Why?
DNA Damage1201324690.010 Why?
Research1201119790.010 Why?
Models, Genetic1201334470.010 Why?
Neoplasm Proteins1201536040.010 Why?
Antidepressive Agents1199529130.010 Why?
Mass Spectrometry1201022020.010 Why?
In Situ Hybridization1200619040.010 Why?
Lymphocyte Activation1201355050.010 Why?
Molecular Sequence Data22006176230.010 Why?
Health Care Reform1201112560.010 Why?
Clinical Trials, Phase III as Topic120068780.010 Why?
Cyclin-Dependent Kinase 6120053540.010 Why?
Role Playing12001210.010 Why?
DNA Primers1200628280.010 Why?
United States42016730390.010 Why?
Drug Discovery1201010680.010 Why?
Computational Biology1201435670.010 Why?
Cyclin-Dependent Kinases120056630.010 Why?
Amino Acid Motifs120049300.010 Why?
Cyclin-Dependent Kinase 4120055650.010 Why?
STAT3 Transcription Factor120058740.010 Why?
Massachusetts1201488900.010 Why?
Registries1201783750.010 Why?
Chromosome Deletion1200513850.010 Why?
Radiotherapy Dosage1200729160.010 Why?
Coronary Disease1199559190.010 Why?
Reverse Transcriptase Polymerase Chain Reaction1200745850.010 Why?
Japan1200414180.010 Why?
ROC Curve1200736280.010 Why?
Homozygote1200417790.010 Why?
Health Policy1201126970.010 Why?
Analysis of Variance1200762290.010 Why?
Phosphoproteins1200724510.010 Why?
Cohort Studies12021417530.010 Why?
Feedback120017990.010 Why?
Paclitaxel1200517330.010 Why?
Socioeconomic Factors1201178520.010 Why?
Transcription, Genetic1201176090.010 Why?
Respiratory Insufficiency1200612400.010 Why?
Early Detection of Cancer1201132390.010 Why?
Vascular Endothelial Growth Factor A1200835170.010 Why?
Repressor Proteins1200729820.010 Why?
Phenotype22010167260.010 Why?
Protein Conformation1200439560.010 Why?
Healthcare Disparities1201134150.010 Why?
Immunotherapy1201147540.010 Why?
Child22016809170.010 Why?
Moclobemide1199540.010 Why?
Interviews as Topic1200327410.010 Why?
Adolescent22021891690.010 Why?
Health Services Accessibility1201155200.010 Why?
DNA1200772130.010 Why?
Lymph Nodes1200534740.010 Why?
Neoadjuvant Therapy1200529070.010 Why?
Sexual Dysfunctions, Psychological119951930.010 Why?
Amino Acid Sequence12004134220.010 Why?
Personality Inventory1199510180.010 Why?
Multivariate Analysis12005120770.010 Why?
Liver Neoplasms1200743630.010 Why?
Randomized Controlled Trials as Topic12008103970.010 Why?
Patient Satisfaction1200334900.010 Why?
Cardiovascular Diseases12016156620.010 Why?
Genetic Predisposition to Disease12011180650.010 Why?
Magnetic Resonance Imaging12013367410.000 Why?
Psychometrics1199530630.000 Why?
Pain Measurement1199535830.000 Why?
B-Lymphocytes1199547930.000 Why?
Double-Blind Method11995124660.000 Why?
Anxiety1199546720.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.