Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Pasi Antero Janne, M.D.,Ph.D.

Concepts (484)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Carcinoma, Non-Small-Cell Lung60202351714.070 Why?
Lung Neoplasms792023130193.540 Why?
Quinazolines25201213552.620 Why?
Protein Kinase Inhibitors35202355222.350 Why?
Receptor, erbB-3720211422.050 Why?
Exons11202224311.860 Why?
Antineoplastic Agents392022136551.660 Why?
Mesothelioma1320088181.430 Why?
Drug Resistance, Neoplasm19202151631.430 Why?
Proto-Oncogene Proteins p21(ras)14202316831.330 Why?
Pleural Neoplasms920086071.230 Why?
Aniline Compounds420239831.220 Why?
Mutation412023297171.080 Why?
Proto-Oncogene Proteins c-met820205781.080 Why?
Receptor, erbB-27202224101.060 Why?
Genes, ras720216910.930 Why?
Antineoplastic Combined Chemotherapy Protocols212020114720.860 Why?
Mutagenesis, Insertional320226550.810 Why?
Gene Amplification6202010620.800 Why?
Cell Line, Tumor372023166650.780 Why?
Benzeneacetamides12019390.690 Why?
Guanine520082740.650 Why?
Acrylamides220202520.650 Why?
Glutamates520083980.640 Why?
Camptothecin120215720.630 Why?
Indoles3202118340.620 Why?
Oncogenes3202112630.590 Why?
Pyrimidines8202329330.550 Why?
Drug Screening Assays, Antitumor120187310.540 Why?
High-Throughput Nucleotide Sequencing6202135850.520 Why?
Adenocarcinoma9201663470.520 Why?
Immunoconjugates120218970.480 Why?
Thiazoles3201914840.480 Why?
Xenograft Model Antitumor Assays7202035570.450 Why?
Proto-Oncogene Proteins11202045530.450 Why?
High-Throughput Screening Assays220189440.450 Why?
Maximum Tolerated Dose620218910.400 Why?
T-Lymphocytes, Cytotoxic1201818200.390 Why?
Enzyme Inhibitors7202338000.390 Why?
ras Proteins5202010600.380 Why?
Adenocarcinoma, Bronchiolo-Alveolar22007910.360 Why?
MAP Kinase Kinase 1220123370.350 Why?
Carboplatin220127990.350 Why?
Taxoids120126650.340 Why?
Humans12220237420880.330 Why?
MAP Kinase Signaling System6202015250.330 Why?
Mutation, Missense5202325560.330 Why?
Heptanoic Acids120113430.330 Why?
Cisplatin5200616370.320 Why?
Oncogene Proteins v-erbB12007170.320 Why?
Benzimidazoles220138480.320 Why?
Sulfones320184370.320 Why?
Apoptosis11202197150.310 Why?
Proto-Oncogene Proteins c-ret220202200.300 Why?
MAP Kinase Kinase 212007960.290 Why?
Morpholines220075610.290 Why?
Mice242021810450.290 Why?
Oncogene Proteins, Fusion4202015810.280 Why?
Pyrazoles4202019700.280 Why?
Disease-Free Survival8202168910.280 Why?
Quinolines420207190.280 Why?
Phosphatidylinositol 3-Kinases8201829380.280 Why?
Gene Expression Regulation, Neoplastic9202084250.280 Why?
Receptors, Growth Factor120073340.270 Why?
Quinazolinones120072210.270 Why?
DNA, Neoplasm7201817580.270 Why?
Pyridazines220202010.270 Why?
Deoxyribonuclease I120062280.260 Why?
Signal Transduction152019233870.260 Why?
Proto-Oncogene Proteins c-akt10201325020.250 Why?
In Situ Hybridization, Fluorescence5201826380.250 Why?
Mitogen-Activated Protein Kinases3201212840.240 Why?
Animals3120211685610.240 Why?
Treatment Outcome242021629660.240 Why?
Benzamides5202013780.230 Why?
DNA Mutational Analysis8201941870.230 Why?
Aged, 80 and over242021576830.230 Why?
Phosphorylation11201284360.220 Why?
Dose-Response Relationship, Drug72021109430.220 Why?
Survival Analysis122008102480.220 Why?
raf Kinases220201220.220 Why?
Aged4120211629440.220 Why?
Loss of Heterozygosity220046780.210 Why?
Carcinoid Tumor120042350.210 Why?
Middle Aged4420212131270.210 Why?
Disease Models, Animal92021180060.210 Why?
Protein-Tyrosine Kinases7202024550.200 Why?
Cell Proliferation102020104720.200 Why?
Female5220233795920.200 Why?
Receptor Protein-Tyrosine Kinases4201316590.200 Why?
Imidazoles2202012050.200 Why?
Tumor Cells, Cultured4202063130.190 Why?
Food-Drug Interactions12020270.190 Why?
NIH 3T3 Cells320196770.190 Why?
ras-GRF112020260.190 Why?
Proto-Oncogene Proteins B-raf3201820280.180 Why?
Antibodies, Bispecific120221640.180 Why?
Receptor, Fibroblast Growth Factor, Type 2120211870.180 Why?
Amino Acid Substitution4201717920.180 Why?
Mice, Transgenic6201997350.180 Why?
Drug Synergism4201917910.180 Why?
Acetonitriles12019520.180 Why?
Male4820213495380.180 Why?
Cell Transformation, Neoplastic3201129400.170 Why?
Receptors, CXCR12019520.170 Why?
Peritoneal Neoplasms120056630.170 Why?
Adult3720212137120.170 Why?
Antibodies, Monoclonal6201792740.170 Why?
Pyridines4202028180.170 Why?
Luciferases, Firefly12018460.160 Why?
Receptors, Fibroblast Growth Factor120191850.160 Why?
Adaptor Proteins, Signal Transducing3200729150.160 Why?
Genomics8202356920.160 Why?
Neoplasm Metastasis4202148390.160 Why?
Mice, Inbred NOD2202018750.160 Why?
Spheroids, Cellular120203510.160 Why?
Allosteric Regulation120194080.150 Why?
Mice, SCID2202027150.150 Why?
Pyrrolidines120193420.150 Why?
Meningeal Neoplasms1200612410.150 Why?
Disease Progression92017132560.150 Why?
Epidermal Growth Factor320057090.150 Why?
Personality120005480.140 Why?
Infusions, Intravenous1202122710.140 Why?
Drug Administration Schedule5200849290.140 Why?
Small Cell Lung Carcinoma120213840.140 Why?
Oligonucleotide Array Sequence Analysis2200739200.140 Why?
Janus Kinase 2220185270.140 Why?
DNA Copy Number Variations2201819400.140 Why?
Alleles2200669310.130 Why?
Smoking2201289690.130 Why?
Bile Duct Neoplasms120215670.130 Why?
Molecular Conformation120175630.130 Why?
Cholangiocarcinoma120215160.130 Why?
TOR Serine-Threonine Kinases5202321070.130 Why?
Mitogen-Activated Protein Kinase 3320074800.130 Why?
Killer Cells, Natural2202221330.130 Why?
Janus Kinase 312015780.130 Why?
Codon120176110.130 Why?
Membrane Proteins3202278730.130 Why?
Neoplasms92020215960.130 Why?
Piperazines2201924880.130 Why?
Pyrrolidinones120151170.130 Why?
Coculture Techniques1201813410.120 Why?
Iodine Radioisotopes1201810300.120 Why?
Gene Dosage3201012510.120 Why?
Prognosis102023290100.120 Why?
Neoplasm Staging62020110010.120 Why?
Receptor, Fibroblast Growth Factor, Type 3120141050.120 Why?
Cell Cycle4201329640.120 Why?
Cell Culture Techniques1202116700.120 Why?
Polymorphism, Single Nucleotide42016154940.120 Why?
Gene Knockout Techniques120178080.120 Why?
Carcinoma, Neuroendocrine120183250.120 Why?
Nucleoside-Phosphate Kinase12013230.120 Why?
Epithelial-Mesenchymal Transition220197130.120 Why?
Immunotherapy, Adoptive1202212550.120 Why?
Clinical Trials as Topic6201679010.110 Why?
Immunity1201910110.110 Why?
Cell Survival3201958720.110 Why?
Naphthyridines120131180.110 Why?
Internal-External Control320033630.110 Why?
Carcinoma, Small Cell220054200.110 Why?
Molecular Targeted Therapy6202127230.100 Why?
ran GTP-Binding Protein12011540.100 Why?
RNA Interference4201328900.100 Why?
Mice, Nude4201936890.100 Why?
Evidence-Based Practice120165000.100 Why?
Receptors, Mitogen12011620.100 Why?
Tumor Suppressor Proteins2201328420.100 Why?
Phenylurea Compounds120145260.100 Why?
Oncogene Proteins120157490.100 Why?
Adaptive Immunity120167120.100 Why?
Tumor Escape120133490.090 Why?
src-Family Kinases220115510.090 Why?
Point Mutation2200616240.090 Why?
Protein Structure, Tertiary3200638470.090 Why?
Cell Differentiation12007114700.090 Why?
Placebos2201216770.090 Why?
Transfection3200658920.090 Why?
Enzyme Activation3201537010.090 Why?
Sequence Analysis120102560.090 Why?
Butadienes220071100.080 Why?
Colorectal Neoplasms2200767540.080 Why?
Genome, Human3201644200.080 Why?
Clinical Trials, Phase I as Topic220203190.080 Why?
Genotype42018129460.080 Why?
Combined Modality Therapy6200786210.080 Why?
AMP-Activated Protein Kinases220136080.080 Why?
Hematopoiesis1201820660.080 Why?
Models, Molecular2201754540.080 Why?
Antigens, Neoplasm1201619830.080 Why?
Extracellular Signal-Regulated MAP Kinases220126250.080 Why?
Genes, p53220077550.080 Why?
Folic Acid Antagonists12008820.080 Why?
Mutant Proteins120105000.080 Why?
Receptor, Platelet-Derived Growth Factor alpha120103790.080 Why?
Fusion Proteins, bcr-abl120104330.080 Why?
Cell Division2200745640.080 Why?
Mutagenesis, Site-Directed2201417230.080 Why?
Tumor Suppressor Protein p531201829480.080 Why?
Treatment Failure4200726150.070 Why?
Protein Binding2201793870.070 Why?
CHO Cells2200714070.070 Why?
Genes, p16120071570.070 Why?
Mosaicism120104400.070 Why?
Neoplasm Recurrence, Local2202091850.070 Why?
Bronchial Neoplasms120071120.070 Why?
Gene Expression2201777900.070 Why?
Chromosome Mapping2200647420.070 Why?
Adenosine Triphosphate1201320240.070 Why?
Sequence Analysis, DNA2201648010.070 Why?
Immunohistochemistry52018113630.070 Why?
Stress, Psychological2200342290.070 Why?
Chromatography, High Pressure Liquid2201015740.070 Why?
Cricetinae2200724710.070 Why?
Proto-Oncogene Proteins c-kit120107740.070 Why?
Liver Failure, Acute120071650.070 Why?
Doxycycline120073260.070 Why?
Radiation Pneumonitis120061040.070 Why?
Sirolimus3201215620.070 Why?
Genes, Neoplasm120073760.070 Why?
Chromones120051540.070 Why?
Nuclear Proteins2202358510.070 Why?
Survival120051620.070 Why?
Transforming Growth Factor alpha120051350.060 Why?
Cricetulus120078170.060 Why?
Proto-Oncogene Proteins c-bcl-23202314340.060 Why?
CD8-Positive T-Lymphocytes1201844380.060 Why?
Paraffin Embedding120062990.060 Why?
Inhibitory Concentration 50120054590.060 Why?
Cell Growth Processes120054000.060 Why?
Thrombocythemia, Essential120061030.060 Why?
Pleura120062350.060 Why?
Class I Phosphatidylinositol 3-Kinases320188900.060 Why?
Sequence Deletion2200615260.060 Why?
Head and Neck Neoplasms1201827120.060 Why?
Cell Shape120053750.060 Why?
Interleukin-3120054410.060 Why?
Thyroid Neoplasms1201822740.060 Why?
Colonic Neoplasms1201625420.060 Why?
Polycythemia Vera120061630.060 Why?
Formaldehyde120063530.060 Why?
Hepatocyte Growth Factor120052700.060 Why?
Antimetabolites, Antineoplastic120086400.060 Why?
Polymerase Chain Reaction3201061710.060 Why?
Nitriles220079520.060 Why?
Deoxycytidine120088240.060 Why?
Medical Oncology3201122350.060 Why?
Cell Cycle Proteins2201334440.060 Why?
Pneumonectomy2200710930.060 Why?
Finland120056020.060 Why?
Eukaryotic Initiation Factor-4F12023410.060 Why?
Genes, erbB-1120041610.060 Why?
Administration, Oral3200739130.060 Why?
Follow-Up Studies52020390040.060 Why?
Exanthema120074880.050 Why?
Protein-Arginine N-Methyltransferases120231310.050 Why?
Mice, Inbred C57BL22018218210.050 Why?
Genes, Tumor Suppressor1200710970.050 Why?
Hyperthermia, Induced120064010.050 Why?
Survival Rate22007127730.050 Why?
Nucleic Acid Hybridization1200413740.050 Why?
Cloning, Molecular1200743220.050 Why?
Models, Biological1201895810.050 Why?
Tuberous Sclerosis1201010290.050 Why?
Sensitivity and Specificity42019147200.050 Why?
Microsatellite Repeats120048000.050 Why?
Antibiotics, Antineoplastic120056920.050 Why?
Prospective Studies72019531870.050 Why?
Tomography, X-Ray Computed42018200860.050 Why?
Biopsy, Needle1200616400.050 Why?
Depression1200077330.050 Why?
Remission Induction1200623840.050 Why?
Blotting, Western2200751800.050 Why?
Biomedical Research1201633060.050 Why?
Gene Expression Profiling3201694100.050 Why?
Diarrhea1200713430.050 Why?
NF-E2-Related Factor 2120233640.050 Why?
Carcinoma1201123740.040 Why?
Tumor Microenvironment3201935640.040 Why?
Radiotherapy, Intensity-Modulated120068060.040 Why?
Terminal Care1201116880.040 Why?
Receptor, trkA120201640.040 Why?
Tumor Burden2201719050.040 Why?
Radiotherapy, Adjuvant3201117690.040 Why?
Medical History Taking120037830.040 Why?
Chromosome Aberrations1200518110.040 Why?
Neoplasms, Experimental2201912740.040 Why?
Cytokines1201373170.040 Why?
Communication2200337280.040 Why?
HEK293 Cells2202042000.040 Why?
Databases, Genetic2201617800.040 Why?
Base Sequence22006127970.040 Why?
Neovascularization, Pathologic1200826330.040 Why?
Gene Knockdown Techniques2201316550.040 Why?
DNA Helicases120238610.040 Why?
Genetic Markers1200426330.040 Why?
Quinoxalines120192880.040 Why?
Antibodies1200524590.040 Why?
Confidence Intervals3200729700.040 Why?
Patient Selection2200742140.040 Why?
Cluster Analysis1200427130.040 Why?
T-Lymphocytes22013101630.040 Why?
Quality of Life22011127300.040 Why?
National Human Genome Research Institute (U.S.)12016230.040 Why?
Drug Delivery Systems1200822170.040 Why?
Tissue Distribution1202023350.040 Why?
Software2201644340.030 Why?
Education, Medical, Continuing120018390.030 Why?
Drug Therapy, Combination1200664830.030 Why?
Predictive Value of Tests32007150560.030 Why?
Young Adult52021563500.030 Why?
Multiprotein Complexes2201211190.030 Why?
Genome1200418030.030 Why?
DNA-Binding Proteins1201396390.030 Why?
Germ-Line Mutation2201617860.030 Why?
Population Groups120162080.030 Why?
MAP Kinase Kinase Kinases120162610.030 Why?
Cell Movement2200552120.030 Why?
Immunophenotyping1201918660.030 Why?
Analgesia, Patient-Controlled119951090.030 Why?
Retrospective Studies62018770980.030 Why?
Lung2201998260.030 Why?
Risk Assessment22006233200.030 Why?
Kaplan-Meier Estimate2201765340.030 Why?
False Positive Reactions120169810.030 Why?
Thymine Nucleotides12013630.030 Why?
Lymphocytes, Tumor-Infiltrating1201910380.030 Why?
Algorithms12014138530.030 Why?
Forecasting1200329480.030 Why?
Genetic Heterogeneity120167320.030 Why?
Okadaic Acid12012670.030 Why?
Receptors, Virus120166480.030 Why?
Depressive Disorder2199537480.030 Why?
Gene Rearrangement1201711790.020 Why?
Binding, Competitive1201311590.020 Why?
Furans120121940.020 Why?
Palliative Care1200634780.020 Why?
Sulfonamides1202019320.020 Why?
T-Lymphocyte Subsets1201918370.020 Why?
Fluoxetine119957490.020 Why?
Breast Neoplasms22011207740.020 Why?
Inhibitor of Apoptosis Proteins120122150.020 Why?
HSP90 Heat-Shock Proteins120134340.020 Why?
Feasibility Studies1202050620.020 Why?
Health Status1200440300.020 Why?
Chemotherapy, Adjuvant2201134710.020 Why?
STAT1 Transcription Factor120123200.020 Why?
Social Support1200021170.020 Why?
Phosphoprotein Phosphatases120123370.020 Why?
Mice, Inbred BALB C1201963820.020 Why?
Morphine119956570.020 Why?
International Cooperation1201714210.020 Why?
Receptors, Antigen, T-Cell1201925240.020 Why?
Sex Factors12004103920.020 Why?
Active Transport, Cell Nucleus120114380.020 Why?
Osteopontin120112960.020 Why?
Western World12009270.020 Why?
Age Factors12007183550.020 Why?
Feedback, Physiological120124790.020 Why?
Adaptation, Psychological1200025750.020 Why?
Threonine120102790.020 Why?
Research Design1200559790.020 Why?
Attitude of Health Personnel1200338390.020 Why?
Cytogenetic Analysis120092950.020 Why?
Pedigree1201646460.020 Why?
Positron-Emission Tomography2201562590.020 Why?
bcl-X Protein120104110.020 Why?
Statistics, Nonparametric1201428850.020 Why?
Physician-Patient Relations1200132150.020 Why?
Anthracenes12007840.020 Why?
Cell Death1201316950.020 Why?
Pilot Projects1202082970.020 Why?
Nucleic Acid Denaturation120071100.020 Why?
Proteins2201260960.020 Why?
Multigene Family1201011020.020 Why?
Apoptosis Regulatory Proteins1201211580.020 Why?
Tablets120061470.020 Why?
DNA Replication1201313970.020 Why?
Cell Line22013159940.020 Why?
Shc Signaling Adaptor Proteins12005460.020 Why?
In Situ Nick-End Labeling120076430.020 Why?
Tumor Stem Cell Assay120051180.020 Why?
PTEN Phosphohydrolase1201111440.020 Why?
Italy120078280.020 Why?
JNK Mitogen-Activated Protein Kinases120074520.020 Why?
Attitude to Health1199520510.020 Why?
Molecular Structure1201019070.020 Why?
Time Factors22005400540.020 Why?
Drug Approval120117400.020 Why?
Coronary Artery Bypass1199522810.020 Why?
Secondary Prevention1201115200.020 Why?
Kinetics1201364740.020 Why?
Autophagy1201313010.020 Why?
Electrophoresis, Polyacrylamide Gel1200718010.020 Why?
Immunoprecipitation120079050.020 Why?
Pain, Postoperative1199516380.020 Why?
Physicians1200345540.020 Why?
Metabolomics1201314670.020 Why?
Hospice Care120116710.020 Why?
Endonucleases120073810.020 Why?
p38 Mitogen-Activated Protein Kinases120076970.020 Why?
Genetics, Population120099330.020 Why?
Protein Processing, Post-Translational1201219890.020 Why?
Electronic Health Records1202144400.010 Why?
Primary Prevention1201111660.010 Why?
Radiography1201570100.010 Why?
Educational Status1201125330.010 Why?
Gene Deletion1201127510.010 Why?
Brain Neoplasms1200588290.010 Why?
Neoplasm Invasiveness1201136120.010 Why?
Controlled Clinical Trials as Topic120041870.010 Why?
Transcription Factors12023121640.010 Why?
DNA Damage1201324230.010 Why?
Up-Regulation1201242110.010 Why?
Research1201119990.010 Why?
Cyclin-Dependent Kinase 6120053220.010 Why?
Antidepressive Agents1199528380.010 Why?
Models, Genetic1201334930.010 Why?
Clinical Trials, Phase III as Topic120068390.010 Why?
Neoplasm Proteins1201536910.010 Why?
Mass Spectrometry1201022030.010 Why?
United States42016696930.010 Why?
Lymphocyte Activation1201355190.010 Why?
In Situ Hybridization1200619500.010 Why?
Role Playing12001240.010 Why?
Health Care Reform1201112610.010 Why?
Molecular Sequence Data22006181120.010 Why?
DNA Primers1200628920.010 Why?
Cyclin-Dependent Kinase 4120055350.010 Why?
Computational Biology1201435180.010 Why?
Drug Discovery1201010570.010 Why?
Cyclin-Dependent Kinases120056700.010 Why?
Amino Acid Motifs120049360.010 Why?
STAT3 Transcription Factor120058740.010 Why?
Registries1201780770.010 Why?
Massachusetts1201486620.010 Why?
Radiotherapy Dosage1200728760.010 Why?
Chromosome Deletion1200514000.010 Why?
Japan1200413600.010 Why?
Coronary Disease1199560780.010 Why?
ROC Curve1200735280.010 Why?
Reverse Transcriptase Polymerase Chain Reaction1200747510.010 Why?
Homozygote1200417770.010 Why?
Health Policy1201126570.010 Why?
Phosphoproteins1200724400.010 Why?
Analysis of Variance1200763650.010 Why?
Cohort Studies12021404500.010 Why?
Feedback120017930.010 Why?
Paclitaxel1200517070.010 Why?
Socioeconomic Factors1201177700.010 Why?
Early Detection of Cancer1201130700.010 Why?
Respiratory Insufficiency1200611990.010 Why?
Transcription, Genetic1201177210.010 Why?
Vascular Endothelial Growth Factor A1200835020.010 Why?
Phenotype22010163310.010 Why?
Healthcare Disparities1201131510.010 Why?
Repressor Proteins1200730200.010 Why?
Immunotherapy1201144140.010 Why?
Protein Conformation1200440130.010 Why?
Child22016774780.010 Why?
Interviews as Topic1200325360.010 Why?
Moclobemide1199540.010 Why?
Adolescent22021856490.010 Why?
Health Services Accessibility1201151330.010 Why?
Neoadjuvant Therapy1200527210.010 Why?
Sexual Dysfunctions, Psychological119951870.010 Why?
Lymph Nodes1200534650.010 Why?
DNA1200772890.010 Why?
Amino Acid Sequence12004138140.010 Why?
Personality Inventory1199510260.010 Why?
Liver Neoplasms1200742490.010 Why?
Randomized Controlled Trials as Topic1200899410.010 Why?
Multivariate Analysis12005122420.010 Why?
Patient Satisfaction1200333910.010 Why?
Cardiovascular Diseases12016151080.010 Why?
Genetic Predisposition to Disease12011174000.010 Why?
Magnetic Resonance Imaging12013353420.000 Why?
Psychometrics1199529990.000 Why?
Pain Measurement1199534180.000 Why?
B-Lymphocytes1199546640.000 Why?
Double-Blind Method11995120170.000 Why?
Anxiety1199542790.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.