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Amino Acid Substitution

"Amino Acid Substitution" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
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The naturally occurring or experimentally induced replacement of one or more AMINO ACIDS in a protein with another. If a functionally equivalent amino acid is substituted, the protein may retain wild-type activity. Substitution may also diminish, enhance, or eliminate protein function. Experimentally induced substitution is often used to study enzyme activities and binding site properties.


publications
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This graph shows the total number of publications written about "Amino Acid Substitution" by people in Harvard Catalyst Profiles by year, and whether "Amino Acid Substitution" was a major or minor topic of these publication.
Bar chart showing 1177 publications over 29 distinct years, with a maximum of 69 publications in 2009
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.