"Okadaic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specific inhibitor of phosphoserine/threonine protein phosphatase 1 and 2a. It is also a potent tumor promoter. (Thromb Res 1992;67(4):345-54 & Cancer Res 1993;53(2):239-41)
Concept/Terms
Okadaic Acid- Okadaic Acid
- Acid, Okadaic
- Ocadaic Acid
- Acid, Ocadaic
Below are MeSH descriptors whose meaning is more general than "Okadaic Acid".
Below are MeSH descriptors whose meaning is more specific than "Okadaic Acid".
This graph shows the total number of publications written about "Okadaic Acid" by people in Harvard Catalyst Profiles by year, and whether "Okadaic Acid" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 5 | 5 |
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 1 | 2 |
| 1997 | 0 | 4 | 4 |
| 1998 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 6 | 6 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 3 | 3 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 3 | 3 |
| 2006 | 0 | 2 | 2 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
Below are the most recent publications written about "Okadaic Acid" by people in Profiles.
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Metformin prevents the pathological browning of subcutaneous white adipose tissue. Mol Metab. 2019 11; 29:12-23.
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Characterization of Runx2 phosphorylation sites required for TGF-ß1-mediated stimulation of matrix metalloproteinase-13 expression in osteoblastic cells. J Cell Physiol. 2018 Feb; 233(2):1082-1094.
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Threonine-290 regulates nuclear translocation of the human pregnane X receptor through its phosphorylation/dephosphorylation by Ca2+/calmodulin-dependent protein kinase II and protein phosphatase 1. Drug Metab Dispos. 2014 Oct; 42(10):1708-18.
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Phosphorylation of the transcription factor Sp4 is reduced by NMDA receptor signaling. J Neurochem. 2014 May; 129(4):743-52.
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Inhibition of PP2A activity confers a TRAIL-sensitive phenotype during malignant transformation. Mol Cancer Res. 2014 Feb; 12(2):217-27.
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Functional human sperm capacitation requires both bicarbonate-dependent PKA activation and down-regulation of Ser/Thr phosphatases by Src family kinases. Mol Hum Reprod. 2013 Sep; 19(9):570-80.
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Impact of oncogenic driver mutations on feedback between the PI3K and MEK pathways in cancer cells. Biosci Rep. 2012 Aug; 32(4):413-22.
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Controlled release of drugs from gradient hydrogels for high-throughput analysis of cell-drug interactions. Anal Chem. 2012 Feb 07; 84(3):1302-9.
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Integration of a pump and an electrical sensor into a membrane-based PDMS microbioreactor for cell culture and drug testing. Biomed Microdevices. 2011 Oct; 13(5):847-64.
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Protein phosphatase 1-dependent dephosphorylation of Akt is the prime signaling event in sphingosine-induced apoptosis in Jurkat cells. J Cell Biochem. 2011 Apr; 112(4):1138-53.