Lymphocytes, Tumor-Infiltrating
"Lymphocytes, Tumor-Infiltrating" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Lymphocytes that show specificity for autologous tumor cells. Ex vivo isolation and culturing of TIL with interleukin-2, followed by reinfusion into the patient, is one form of adoptive immunotherapy of cancer.
MeSH Number(s)
A11.118.637.555.567.650
A15.145.229.637.555.567.650
A15.382.490.555.567.650
Concept/Terms
Lymphocytes, Tumor-Infiltrating- Lymphocytes, Tumor-Infiltrating
- Lymphocytes, Tumor Infiltrating
- Tumor-Infiltrating Lymphocytes
- Lymphocyte, Tumor-Infiltrating
- Tumor Infiltrating Lymphocytes
- Tumor-Infiltrating Lymphocyte
Tumor-Derived Activated Cells- Tumor-Derived Activated Cells
- Activated Cell, Tumor-Derived
- Activated Cells, Tumor-Derived
- Tumor Derived Activated Cells
- Tumor-Derived Activated Cell
Below are MeSH descriptors whose meaning is more general than "Lymphocytes, Tumor-Infiltrating".
Below are MeSH descriptors whose meaning is more specific than "Lymphocytes, Tumor-Infiltrating".
This graph shows the total number of publications written about "Lymphocytes, Tumor-Infiltrating" by people in Harvard Catalyst Profiles by year, and whether "Lymphocytes, Tumor-Infiltrating" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 3 | 1 | 4 |
1996 | 1 | 2 | 3 |
1997 | 4 | 0 | 4 |
1998 | 1 | 1 | 2 |
1999 | 1 | 3 | 4 |
2000 | 1 | 0 | 1 |
2002 | 1 | 0 | 1 |
2003 | 1 | 2 | 3 |
2004 | 1 | 1 | 2 |
2005 | 0 | 2 | 2 |
2006 | 6 | 2 | 8 |
2007 | 7 | 0 | 7 |
2008 | 4 | 0 | 4 |
2009 | 3 | 4 | 7 |
2010 | 4 | 1 | 5 |
2011 | 3 | 3 | 6 |
2012 | 3 | 4 | 7 |
2013 | 6 | 4 | 10 |
2014 | 6 | 9 | 15 |
2015 | 12 | 5 | 17 |
2016 | 21 | 14 | 35 |
2017 | 21 | 23 | 44 |
2018 | 17 | 16 | 33 |
2019 | 24 | 23 | 47 |
2020 | 10 | 43 | 53 |
2021 | 24 | 31 | 55 |
2022 | 8 | 17 | 25 |
2023 | 2 | 11 | 13 |
2024 | 0 | 3 | 3 |
Below are the most recent publications written about "Lymphocytes, Tumor-Infiltrating" by people in Profiles.
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Objective Analysis and Clinical Significance of the Spatial Tumor-Infiltrating Lymphocyte Patterns in Non-Small Cell Lung Cancer. Clin Cancer Res. 2024 Mar 01; 30(5):998-1008.
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Expert consensus guidelines on management and best practices for tumor-infiltrating lymphocyte cell therapy. J Immunother Cancer. 2024 Feb 29; 12(2).
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Multiplexed high-throughput immune cell imaging in patients with high-risk triple negative early breast cancer: Analysis from the International Breast Cancer Study Group (IBCSG) Trial 22-00. Eur J Cancer. 2024 Mar; 200:113535.
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Phenotypic signatures of circulating neoantigen-reactive CD8+ T cells in patients with metastatic cancers. Cancer Cell. 2023 12 11; 41(12):2154-2165.e5.
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Association of Sarcopenia with a Poor Prognosis and Decreased Tumor-Infiltrating CD8-Positive T Cells in Pancreatic Ductal Adenocarcinoma: A Retrospective Analysis. Ann Surg Oncol. 2024 01; 31(1):16-18.
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Initial interactions with the FDA on developing a validation dataset as a medical device development tool. J Pathol. 2023 Dec; 261(4):378-384.
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Spatial analyses of immune cell infiltration in cancer: current methods and future directions: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer. J Pathol. 2023 08; 260(5):514-532.
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Pitfalls in machine learning-based assessment of tumor-infiltrating lymphocytes in breast cancer: A report of the International Immuno-Oncology Biomarker Working Group on Breast Cancer J Pathol. 2023 08; 260(5):498-513.
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Patterns of Tumor-Infiltrating Lymphocytes Used to Distinguish Primary Cutaneous Squamous Cell Carcinomas That Metastasize. JAMA Dermatol. 2023 07 01; 159(7):788-790.
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GSK-3 Inhibitor Elraglusib Enhances Tumor-Infiltrating Immune Cell Activation in Tumor Biopsies and Synergizes with Anti-PD-L1 in a Murine Model of Colorectal Cancer. Int J Mol Sci. 2023 Jun 29; 24(13).