Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

David E Cohen, M.D., Ph.D.

Concepts (483)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Thiolester Hydrolases162024916.630 Why?
Phospholipid Transfer Proteins232024906.190 Why?
Liver52202375773.740 Why?
Fatty Liver1420248093.320 Why?
Thermogenesis1220244942.210 Why?
Fatty Acids19202318122.170 Why?
Lipid Metabolism21202319042.140 Why?
Triglycerides15202324641.870 Why?
Lipogenesis1020242171.860 Why?
Palmitoyl-CoA Hydrolase52021171.780 Why?
Cholesterol29201629141.730 Why?
Adipose Tissue, Brown1320247761.720 Why?
Insulin Resistance15202439861.700 Why?
Bile Acids and Salts1820193981.370 Why?
Energy Metabolism15202429071.250 Why?
Glucose14202343521.240 Why?
Phosphatidylcholines920234061.010 Why?
Lipoproteins820198800.960 Why?
Mice, Knockout352024144880.920 Why?
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors220243250.820 Why?
Homeostasis9202033480.770 Why?
Lipoproteins, VLDL420192010.760 Why?
Mice712024820290.760 Why?
Obesity202024130900.750 Why?
Glycolysis220248370.720 Why?
Chenodeoxycholic Acid12019340.670 Why?
Up-Regulation5202441460.660 Why?
Animals9120241692460.660 Why?
Glycerol-3-Phosphate O-Acyltransferase1201890.640 Why?
Cyclic AMP Response Element-Binding Protein120215000.620 Why?
Androgen-Binding Protein32002100.610 Why?
Muscle, Skeletal2202449780.590 Why?
Mice, Inbred C57BL282024223790.560 Why?
Mitochondrial Proteins420199790.530 Why?
Hepatocytes11202212470.530 Why?
Diet9202380890.520 Why?
Glucose Intolerance320175790.500 Why?
Carcinoma, Hepatocellular4202323330.480 Why?
Bile420052990.480 Why?
Leptin5201615990.470 Why?
Mitochondria7202136810.470 Why?
Rhinitis, Allergic, Seasonal120151040.460 Why?
Dyslipidemias420168730.450 Why?
Anticholesteremic Agents220149720.450 Why?
PPAR alpha320101770.440 Why?
Calcium Signaling120177370.420 Why?
Fibroblast Growth Factors420218730.420 Why?
Adaptation, Biological120131470.410 Why?
Apolipoproteins B120143860.410 Why?
Mouth Diseases120152390.410 Why?
Hypercholesterolemia5201411450.410 Why?
Fructose420192840.400 Why?
Lipoproteins, HDL320076820.390 Why?
ATP-Binding Cassette Transporters920145670.390 Why?
Insulin7202366070.390 Why?
Liver Neoplasms4202343620.380 Why?
Mice, Obese420174170.380 Why?
Pruritus120153790.380 Why?
Oligonucleotides120145630.370 Why?
Acyl Coenzyme A22020560.370 Why?
Oxidation-Reduction5202122270.360 Why?
Carrier Proteins8201849370.360 Why?
Calorimetry, Indirect420181760.330 Why?
Fruit1201511650.330 Why?
Vegetables1201511990.330 Why?
Cholesterol 7-alpha-Hydroxylase52008280.300 Why?
Gene Deletion3201326750.300 Why?
Adipose Tissue, White620193710.300 Why?
Allylamine12007100.290 Why?
Gallstones320082850.290 Why?
Mice, Inbred Strains5201617650.290 Why?
Intestines1201619090.290 Why?
Phospholipids420077870.290 Why?
Calcium2201757920.280 Why?
Mice, Inbred NZB12006570.280 Why?
Food Hypersensitivity120157340.280 Why?
Paired Box Transcription Factors120072060.270 Why?
Gluconeogenesis220201850.260 Why?
Thyroid Hormones320214070.250 Why?
Glucose Tolerance Test4201611830.250 Why?
Dietary Fats6201420030.250 Why?
Hydroxymethylglutaryl-CoA Reductase Inhibitors4201932510.230 Why?
Stress, Physiological2202414080.230 Why?
Arrestins22017730.230 Why?
Apolipoprotein A-I220053050.230 Why?
Macrophages, Peritoneal120052440.230 Why?
Body Weight4202146270.230 Why?
Receptors, Adrenergic, beta220172430.220 Why?
Liver Failure120062520.220 Why?
Rosacea12024600.220 Why?
Lipids8201733430.210 Why?
PPAR delta12023400.210 Why?
Male4220243647190.210 Why?
Biological Transport5201720850.210 Why?
Enterohepatic Circulation12002120.210 Why?
Cholesterol, HDL4201518200.200 Why?
Apolipoproteins E2201514610.200 Why?
High-Throughput Screening Assays220239420.200 Why?
Weight Loss4201827210.190 Why?
Nobel Prize12021460.190 Why?
Zebrafish Proteins2201910190.190 Why?
Program Development1200713000.180 Why?
Fibrinogen220158910.180 Why?
Lysophosphatidylcholines12020770.180 Why?
Body Temperature220167800.170 Why?
Delphi Technique120248910.170 Why?
Humans5420247681660.170 Why?
Protein Kinase C-epsilon12018430.160 Why?
Paraventricular Hypothalamic Nucleus120191210.160 Why?
Alanine Transaminase220166060.160 Why?
Gene Expression Regulation112017119280.160 Why?
Eating2201615420.160 Why?
Glycerides12018670.160 Why?
Myostatin120201290.160 Why?
Phosphatidylethanolamine Binding Protein3200280.150 Why?
Protein Phosphatase 1120181350.150 Why?
Adiposity4202118950.150 Why?
Membrane Fluidity12017670.150 Why?
Blood Glucose4201764300.150 Why?
Overnutrition12017250.150 Why?
Insulin-Secreting Cells220238990.150 Why?
Eukaryotic Initiation Factor-2120181780.150 Why?
Bariatric Surgery3201610010.140 Why?
Receptor-Like Protein Tyrosine Phosphatases, Class 71201640.140 Why?
Animal Feed120171050.140 Why?
Glutamine220175770.140 Why?
Calcium-Calmodulin-Dependent Protein Kinase Type 2120171800.140 Why?
Pyruvates12016840.140 Why?
Diabetes Mellitus, Experimental1202311240.130 Why?
Cholesterol, LDL3201524030.130 Why?
Atherosclerosis3200834330.130 Why?
Lipolysis120172110.130 Why?
Recombinant Proteins4202065140.130 Why?
MAP Kinase Kinase Kinases120182520.130 Why?
Animal Experimentation12016460.130 Why?
Protein Structure, Tertiary4201037720.130 Why?
Hyperammonemia12017800.130 Why?
Cold Temperature120207910.130 Why?
Prenatal Nutritional Physiological Phenomena120171610.130 Why?
Polymorphism, Genetic1200642490.130 Why?
Cholelithiasis220104080.120 Why?
Cysteine Endopeptidases120185420.120 Why?
Gastrointestinal Contents12015420.120 Why?
Trans-Activators3201628570.120 Why?
Choline120175220.120 Why?
Oxygen Consumption2201318800.120 Why?
Protein Binding5201893430.120 Why?
Bone Morphogenetic Proteins120208450.120 Why?
Mice, Transgenic6201395610.120 Why?
Methionine120175730.120 Why?
Thyroid Hormone Receptors beta12014210.120 Why?
Nuclear Receptor Co-Repressor 112014280.120 Why?
Receptors, LDL220154930.120 Why?
Substrate Specificity2200917510.120 Why?
Hepacivirus1202113440.110 Why?
Intestinal Mucosa5201530440.110 Why?
Consensus1202432120.110 Why?
Panniculitis12014450.110 Why?
Liver Diseases3201813050.110 Why?
Glucagon-Like Peptide 1120163740.110 Why?
Body Composition4201724620.110 Why?
Hydroxymethylglutaryl CoA Reductases22004640.110 Why?
Phosphoproteins2201624510.110 Why?
Societies, Medical2201539680.110 Why?
Receptors, Thrombin120131300.110 Why?
Workflow120188600.110 Why?
Coma120174850.110 Why?
Transcription Factors72023121680.110 Why?
Natural Killer T-Cells120163180.110 Why?
Receptors, CXCR3120142400.110 Why?
MicroRNAs3201538030.110 Why?
Mucus120153460.100 Why?
Cross Reactions120158280.100 Why?
Cloning, Molecular2201241680.100 Why?
Coronavirus Infections2202031150.100 Why?
Inhibitory Concentration 50120134640.100 Why?
Kinetics3202063290.100 Why?
Pneumonia, Viral2202032380.100 Why?
Species Specificity2200724150.100 Why?
Double-Blind Method32019124650.100 Why?
Inhalation Exposure120154320.100 Why?
Diabetes Mellitus, Type 232023122520.100 Why?
Estrogens1201915360.100 Why?
Adipocytes3201911970.100 Why?
Signal Transduction92020236450.100 Why?
Aldehyde Dehydrogenase120121460.100 Why?
TOR Serine-Threonine Kinases3201920620.090 Why?
Estradiol1201919510.090 Why?
Gastrointestinal Diseases1202012060.090 Why?
Chemotaxis, Leukocyte120146600.090 Why?
Hepatitis C1202115950.090 Why?
Receptors, G-Protein-Coupled1201912470.090 Why?
Models, Molecular3200754030.090 Why?
Feeding Behavior2202132050.090 Why?
Malnutrition120176320.090 Why?
Fatty Acids, Nonesterified220133940.090 Why?
Sterol Regulatory Element Binding Proteins12010250.090 Why?
Receptors, Estrogen1201922530.090 Why?
Metabolic Diseases120176840.090 Why?
Blotting, Western2200950270.090 Why?
Crosses, Genetic220097520.090 Why?
Adipose Tissue4201533290.090 Why?
Induced Pluripotent Stem Cells1202118870.080 Why?
Liver Function Tests220145260.080 Why?
Gene Targeting120138410.080 Why?
Hepatocyte Nuclear Factor 4120101270.080 Why?
Fenofibrate12010870.080 Why?
Gaucher Disease120101100.080 Why?
Drug Therapy, Combination1201963160.080 Why?
Iodide Peroxidase120112950.080 Why?
Hydrogen-Ion Concentration2201524860.080 Why?
Apoptosis1200595230.080 Why?
Membrane Proteins4202278760.080 Why?
Cell Membrane3201036550.080 Why?
Base Sequence22012124210.080 Why?
Osmolar Concentration120096570.080 Why?
Protein Folding220098710.080 Why?
Disease Models, Animal42021183490.070 Why?
Clinical Trials as Topic1202480540.070 Why?
Chylomicrons12007270.070 Why?
Cells, Cultured32014190150.070 Why?
Biliary Tract120081350.070 Why?
Microscopy, Electron2200925600.070 Why?
Tissue Distribution3200723000.070 Why?
Steroid Hydroxylases22004930.070 Why?
Glucose Clamp Technique120082630.070 Why?
Lipoprotein-X1200750.070 Why?
DNA Primers1201228280.070 Why?
Phosphorylation2202183170.070 Why?
Scavenger Receptors, Class B12007850.070 Why?
Endoplasmic Reticulum2201011330.070 Why?
Fibrosis1201420800.070 Why?
Multiprotein Complexes1201311100.070 Why?
Gallbladder220053080.070 Why?
Magnetic Resonance Spectroscopy1201737800.070 Why?
Oligonucleotide Array Sequence Analysis3201038000.070 Why?
Norepinephrine120098980.070 Why?
Cell Transformation, Neoplastic1201628460.070 Why?
Two-Hybrid System Techniques120074630.070 Why?
Pulmonary Surfactants120071690.070 Why?
Temperature2201122340.060 Why?
Receptors, Cytoplasmic and Nuclear220088590.060 Why?
T-Lymphocyte Subsets1201418150.060 Why?
Cardiovascular Diseases42016156620.060 Why?
Adaptor Proteins, Signal Transducing1201629090.060 Why?
Logistic Models12020132900.060 Why?
Ligands2202332840.060 Why?
Lactation120083920.060 Why?
Female1920203971920.060 Why?
Cholesterol, Dietary120052240.060 Why?
Amino Acid Motifs120079300.060 Why?
Bile Canaliculi12004120.060 Why?
Reverse Transcriptase Polymerase Chain Reaction2200945800.060 Why?
Bezafibrate12004140.060 Why?
Stearoyl-CoA Desaturase12005840.060 Why?
Enzyme-Linked Immunosorbent Assay1201238140.060 Why?
Nerve Tissue Proteins1201744130.060 Why?
CHO Cells2201013790.060 Why?
Aspartate Aminotransferases120064140.060 Why?
RNA, Messenger62011128000.060 Why?
L-Lactate Dehydrogenase120054120.060 Why?
HEK293 Cells1201342830.060 Why?
Infusions, Parenteral120043960.060 Why?
Cell Culture Techniques2200916670.060 Why?
Cholestasis120073850.060 Why?
Cricetinae2201024230.050 Why?
Cholestasis, Intrahepatic12003750.050 Why?
Gene Expression Profiling2201095380.050 Why?
Tumor Suppressor Proteins1201328100.050 Why?
DNA, Complementary1200619890.050 Why?
Enzyme Induction220174550.050 Why?
Electrophoresis, Polyacrylamide Gel1200517300.050 Why?
Phospholipases A2, Calcium-Independent12022120.050 Why?
Blood Platelets1201324790.050 Why?
Prognosis22013300100.050 Why?
Molecular Structure1200718830.050 Why?
Organ Specificity1200719680.050 Why?
Cell Line32019155970.050 Why?
Biopsy1201467930.050 Why?
Cholesterol, VLDL12002700.050 Why?
Adaptation, Physiological1200913120.050 Why?
Caveolins120021020.050 Why?
NG-Nitroarginine Methyl Ester120022620.050 Why?
Amino Acid Substitution1200617430.050 Why?
Intestinal Absorption120034000.050 Why?
Microscopy, Fluorescence1200926330.050 Why?
Rats, Sprague-Dawley3201581280.050 Why?
Down-Regulation2200829370.050 Why?
Homozygote1200617790.050 Why?
Cerebral Ventricles120045500.050 Why?
X-Ray Diffraction120024160.050 Why?
Cattle1200738190.050 Why?
Adrenergic Agonists12021570.050 Why?
Point Mutation1200615960.050 Why?
Crystallization120025200.050 Why?
Organ Size2201922670.050 Why?
Saccharomyces cerevisiae Proteins1201018390.050 Why?
Aging1202087440.050 Why?
Acyltransferases120223060.040 Why?
DNA-Binding Proteins2200896150.040 Why?
Middle Aged720202234920.040 Why?
Isoenzymes1200516880.040 Why?
Intracellular Space120211990.040 Why?
Lipase120223210.040 Why?
Research Design1201662110.040 Why?
Consultants12020570.040 Why?
9,10-Dimethyl-1,2-benzanthracene12019580.040 Why?
Protein Structure, Secondary1200212160.040 Why?
Infusions, Intravenous1200422300.040 Why?
Growth Differentiation Factors12020990.040 Why?
Nuclear Proteins2201858040.040 Why?
Gene Expression Regulation, Neoplastic1201586470.040 Why?
Evidence-Based Medicine2201437060.040 Why?
Diagnosis, Differential12014130140.040 Why?
Allosteric Regulation120204260.040 Why?
Risk Factors32020749440.040 Why?
Treatment Outcome32024653710.040 Why?
Liver Transplantation2201424010.040 Why?
Drug Resistance1200515990.040 Why?
Risk Assessment12020243150.040 Why?
Protein Transport1200419510.040 Why?
Protein Conformation1200639560.040 Why?
RNA-Binding Proteins1200718900.040 Why?
Cytosol120018870.040 Why?
Macrophages3201057990.040 Why?
United States42020730390.040 Why?
Activating Transcription Factor 412018860.040 Why?
Chromosome Mapping1200646200.040 Why?
Fructokinases1201760.040 Why?
Phosphatidylinositol 3-Kinase120191250.040 Why?
New York120208820.040 Why?
Inflammation12018108730.040 Why?
Crystallography, X-Ray1200219510.040 Why?
MAP Kinase Kinase 4120181470.040 Why?
tRNA Methyltransferases12017500.040 Why?
Sodium Benzoate12017140.040 Why?
Ursodeoxycholic Acid12017810.040 Why?
Serine120218310.040 Why?
Phenylacetates120171120.040 Why?
Liver Regeneration120192140.040 Why?
Disease Progression12014136710.030 Why?
Haplorhini120185230.030 Why?
Mice, Inbred ICR120173620.030 Why?
Rats32015237600.030 Why?
Genetic Predisposition to Disease32017180650.030 Why?
Pulmonary Gas Exchange120183890.030 Why?
Circadian Rhythm1200825930.030 Why?
Gene Expression Regulation, Developmental1200736100.030 Why?
Zebrafish2201930350.030 Why?
Diethylnitrosamine12015450.030 Why?
Aged420201715040.030 Why?
Glutamates120173850.030 Why?
Deficiency Diseases12016740.030 Why?
Receptors, TNF-Related Apoptosis-Inducing Ligand12015580.030 Why?
Digestion12015530.030 Why?
Weight Gain2201923590.030 Why?
Gastrointestinal Hormones120151010.030 Why?
Endocrine System120151130.030 Why?
Sex Factors32019106320.030 Why?
p38 Mitogen-Activated Protein Kinases120186930.030 Why?
Hydrophobic and Hydrophilic Interactions220083930.030 Why?
Viscosity120153340.030 Why?
Elastic Modulus120152110.030 Why?
Embolism, Cholesterol12013320.030 Why?
Orphan Nuclear Receptors12014630.030 Why?
Cytochrome P-450 CYP3A120141180.030 Why?
Transfection1200157550.030 Why?
Binding Sites1200260200.030 Why?
History, 20th Century1202127660.030 Why?
Diarrhea1202013200.030 Why?
Tumor Burden1201919060.030 Why?
HCT116 Cells120134040.030 Why?
Hep G2 Cells120133780.030 Why?
ROC Curve1202036280.030 Why?
Adult420192236460.030 Why?
Retinal Dehydrogenase12012780.030 Why?
Cell Proliferation22019104740.020 Why?
Hepatitis, Autoimmune120141730.020 Why?
Protein Processing, Post-Translational1201919660.020 Why?
Receptors, Retinoic Acid120122290.020 Why?
Iceland120111830.020 Why?
Transcriptional Activation1201717500.020 Why?
Animals, Genetically Modified1201615630.020 Why?
Regression Analysis1202063400.020 Why?
Dose-Response Relationship, Drug12003107600.020 Why?
Platelet Aggregation120137690.020 Why?
Glucosylceramides12010270.020 Why?
Gene Expression2201975980.020 Why?
Pandemics2202087480.020 Why?
Chromosomes, Human, Pair 5120113870.020 Why?
Food120157680.020 Why?
Sterol Regulatory Element Binding Protein 212010580.020 Why?
Dietary Supplements1200334450.020 Why?
Adrenergic beta-Agonists120113470.020 Why?
Brain12017273600.020 Why?
Apoptosis Regulatory Proteins1201511510.020 Why?
Sterol Regulatory Element Binding Protein 1120101350.020 Why?
Analysis of Variance1201862290.020 Why?
Escherichia coli1200242140.020 Why?
Models, Animal1201621200.020 Why?
Time Factors32014402180.020 Why?
Amino Acid Sequence12021134210.020 Why?
Intestine, Small2200712170.020 Why?
Disease Susceptibility2200817930.020 Why?
Cricetulus120108120.020 Why?
Steroid 12-alpha-Hydroxylase1200890.020 Why?
Cholic Acids12008390.020 Why?
Gastric Bypass120178240.020 Why?
Behavior, Animal1201618620.020 Why?
Liver Cirrhosis1201919600.020 Why?
Linear Models1201858840.020 Why?
Ketones120091830.020 Why?
Virus Diseases120147240.020 Why?
3' Untranslated Regions120105150.020 Why?
Massachusetts1202088900.020 Why?
Introns120109660.020 Why?
Oligonucleotides, Antisense120104620.020 Why?
Ion Channels1201210430.020 Why?
Sequence Homology, Amino Acid1201127480.020 Why?
Phosphatidylcholine-Sterol O-Acyltransferase12007330.020 Why?
Fasting1201316100.020 Why?
Integrases120095200.020 Why?
Proto-Oncogene Proteins c-akt1201524570.020 Why?
Linkage Disequilibrium1201119970.020 Why?
Hospital Mortality1202053490.020 Why?
Enterocytes120072200.020 Why?
Blotting, Northern1200715500.020 Why?
Neoplasm Proteins1201836030.020 Why?
Transcription, Genetic1201976080.020 Why?
Inflammation Mediators1201418920.020 Why?
Incidence22016215380.010 Why?
Swine1201559950.010 Why?
4-Chloro-7-nitrobenzofurazan12004210.010 Why?
Prenatal Exposure Delayed Effects1201725380.010 Why?
Lysosomes120109380.010 Why?
Hyperglycemia1201313880.010 Why?
Receptor, Insulin120088390.010 Why?
Models, Biological2201094950.010 Why?
Dietary Carbohydrates120088960.010 Why?
Sterols12003640.010 Why?
Body Mass Index22011130530.010 Why?
Gastrointestinal Transit120031010.010 Why?
Detergents120022350.010 Why?
Genetic Loci1201126290.010 Why?
Antiviral Agents1201430730.010 Why?
RNA Interference1201028320.010 Why?
Proportional Hazards Models12016125430.010 Why?
Nitric Oxide Synthase Type II120025140.010 Why?
Sensitivity and Specificity12016147290.010 Why?
Promoter Regions, Genetic1201257970.010 Why?
Caveolin 1120022550.010 Why?
Hospitalization12020108400.010 Why?
Reproducibility of Results12018202270.010 Why?
RNA, Small Interfering1200934280.010 Why?
Severity of Illness Index12018159480.010 Why?
Thrombosis1201329570.010 Why?
Saccharomyces cerevisiae1201026820.010 Why?
Phenotype22010167260.010 Why?
Nitric Oxide Synthase120029110.010 Why?
Nitric Oxide Synthase Type III120027060.010 Why?
Capillaries120027550.010 Why?
Serum Albumin120026770.010 Why?
Capillary Permeability120027720.010 Why?
Adenoviridae1200210920.010 Why?
Cohort Studies22011417540.010 Why?
Integrins120028420.010 Why?
Mutation12002302380.010 Why?
Microcirculation1200212810.010 Why?
Magnetic Resonance Imaging12005367430.010 Why?
Genome-Wide Association Study12015127950.010 Why?
Polymorphism, Single Nucleotide12015160450.010 Why?
Pregnancy12017302560.010 Why?
Aged, 80 and over12020596290.010 Why?
Immunohistochemistry12007110950.010 Why?
Prevalence12010158690.010 Why?
Enzyme Inhibitors1200237280.010 Why?
Retrospective Studies12020817620.010 Why?
Prospective Studies12016549260.010 Why?
Endothelium, Vascular1200244270.010 Why?
Genotype12004130450.010 Why?
Adolescent12017891690.000 Why?
Cell Line, Tumor12004171400.000 Why?
Lung12002100990.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.