Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

David E Cohen, M.D., Ph.D.

Concepts (483)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Thiolester Hydrolases162024916.590 Why?
Phospholipid Transfer Proteins232024906.160 Why?
Liver52202375583.730 Why?
Fatty Liver1420248103.300 Why?
Thermogenesis1220244952.200 Why?
Fatty Acids19202318062.170 Why?
Lipid Metabolism21202318952.130 Why?
Triglycerides15202324411.870 Why?
Lipogenesis1020242171.850 Why?
Palmitoyl-CoA Hydrolase52021171.770 Why?
Cholesterol29201629011.730 Why?
Adipose Tissue, Brown1320247751.710 Why?
Insulin Resistance15202439881.690 Why?
Bile Acids and Salts1820193981.360 Why?
Energy Metabolism15202428971.250 Why?
Glucose14202343351.240 Why?
Phosphatidylcholines920234031.000 Why?
Lipoproteins820198700.960 Why?
Mice, Knockout352024144570.920 Why?
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors220243230.820 Why?
Homeostasis9202033380.770 Why?
Lipoproteins, VLDL420191980.760 Why?
Mice712024818380.760 Why?
Obesity202024130820.750 Why?
Glycolysis220248370.720 Why?
Up-Regulation5202441330.660 Why?
Chenodeoxycholic Acid12019340.660 Why?
Animals9120241688010.660 Why?
Glycerol-3-Phosphate O-Acyltransferase1201890.640 Why?
Cyclic AMP Response Element-Binding Protein120215010.610 Why?
Androgen-Binding Protein32002100.610 Why?
Muscle, Skeletal2202449600.590 Why?
Mice, Inbred C57BL282024223390.560 Why?
Mitochondrial Proteins420199750.530 Why?
Hepatocytes11202212450.530 Why?
Diet9202380850.520 Why?
Glucose Intolerance320175780.500 Why?
Carcinoma, Hepatocellular4202323280.480 Why?
Bile420053000.470 Why?
Leptin5201615960.470 Why?
Mitochondria7202136760.470 Why?
Rhinitis, Allergic, Seasonal120151010.460 Why?
Dyslipidemias420168710.450 Why?
Anticholesteremic Agents220149700.450 Why?
PPAR alpha320101770.440 Why?
Calcium Signaling120177340.420 Why?
Fibroblast Growth Factors420218710.420 Why?
Adaptation, Biological120131470.410 Why?
Apolipoproteins B120143850.410 Why?
Mouth Diseases120152390.410 Why?
Hypercholesterolemia5201411450.400 Why?
Fructose420192840.390 Why?
Lipoproteins, HDL320076760.390 Why?
ATP-Binding Cassette Transporters920145660.390 Why?
Insulin7202366030.380 Why?
Liver Neoplasms4202343540.380 Why?
Mice, Obese420174170.380 Why?
Pruritus120153760.380 Why?
Oligonucleotides120145610.370 Why?
Acyl Coenzyme A22020560.370 Why?
Oxidation-Reduction5202122230.360 Why?
Carrier Proteins8201849100.360 Why?
Calorimetry, Indirect420181760.330 Why?
Fruit1201511660.330 Why?
Vegetables1201511990.320 Why?
Cholesterol 7-alpha-Hydroxylase52008280.300 Why?
Gene Deletion3201326670.300 Why?
Adipose Tissue, White620193700.300 Why?
Allylamine12007100.290 Why?
Gallstones320082850.290 Why?
Mice, Inbred Strains5201617690.290 Why?
Intestines1201619040.290 Why?
Phospholipids420077770.290 Why?
Calcium2201757700.280 Why?
Mice, Inbred NZB12006570.280 Why?
Food Hypersensitivity120157340.270 Why?
Paired Box Transcription Factors120072040.270 Why?
Gluconeogenesis220201820.260 Why?
Glucose Tolerance Test4201611800.250 Why?
Thyroid Hormones320214080.250 Why?
Dietary Fats6201420010.250 Why?
Hydroxymethylglutaryl-CoA Reductase Inhibitors4201932490.230 Why?
Stress, Physiological2202414040.230 Why?
Arrestins22017730.230 Why?
Macrophages, Peritoneal120052430.230 Why?
Apolipoprotein A-I220053050.230 Why?
Body Weight4202146260.230 Why?
Receptors, Adrenergic, beta220172420.220 Why?
Liver Failure120062520.220 Why?
Rosacea12024600.220 Why?
Lipids8201733170.210 Why?
PPAR delta12023400.210 Why?
Male4220243638800.210 Why?
Biological Transport5201720800.210 Why?
Enterohepatic Circulation12002120.210 Why?
Cholesterol, HDL4201518110.200 Why?
Apolipoproteins E2201514590.200 Why?
High-Throughput Screening Assays220239380.200 Why?
Weight Loss4201827110.190 Why?
Nobel Prize12021460.190 Why?
Zebrafish Proteins2201910170.180 Why?
Program Development1200712970.180 Why?
Fibrinogen220158940.180 Why?
Lysophosphatidylcholines12020770.170 Why?
Body Temperature220167810.170 Why?
Delphi Technique120248920.170 Why?
Humans5420247660190.170 Why?
Protein Kinase C-epsilon12018430.160 Why?
Gene Expression Regulation112017119060.160 Why?
Paraventricular Hypothalamic Nucleus120191210.160 Why?
Alanine Transaminase220166080.160 Why?
Eating2201615380.160 Why?
Glycerides12018670.160 Why?
Myostatin120201290.160 Why?
Phosphatidylethanolamine Binding Protein3200280.150 Why?
Protein Phosphatase 1120181350.150 Why?
Adiposity4202118920.150 Why?
Blood Glucose4201764200.150 Why?
Membrane Fluidity12017670.150 Why?
Overnutrition12017250.150 Why?
Insulin-Secreting Cells220238990.150 Why?
Eukaryotic Initiation Factor-2120181780.140 Why?
Bariatric Surgery320169970.140 Why?
Receptor-Like Protein Tyrosine Phosphatases, Class 71201640.140 Why?
Animal Feed120171050.140 Why?
Glutamine220175750.140 Why?
Calcium-Calmodulin-Dependent Protein Kinase Type 2120171790.140 Why?
Pyruvates12016840.140 Why?
Cholesterol, LDL3201523920.130 Why?
Diabetes Mellitus, Experimental1202311190.130 Why?
Atherosclerosis3200834170.130 Why?
Recombinant Proteins4202064920.130 Why?
Lipolysis120172110.130 Why?
MAP Kinase Kinase Kinases120182520.130 Why?
Animal Experimentation12016460.130 Why?
Protein Structure, Tertiary4201037500.130 Why?
Hyperammonemia12017800.130 Why?
Cold Temperature120207940.130 Why?
Polymorphism, Genetic1200642480.130 Why?
Prenatal Nutritional Physiological Phenomena120171610.130 Why?
Cholelithiasis220104080.120 Why?
Trans-Activators3201628490.120 Why?
Cysteine Endopeptidases120185420.120 Why?
Choline120175110.120 Why?
Gastrointestinal Contents12015420.120 Why?
Protein Binding5201893020.120 Why?
Oxygen Consumption2201318700.120 Why?
Bone Morphogenetic Proteins120208440.120 Why?
Mice, Transgenic6201395400.120 Why?
Methionine120175690.120 Why?
Thyroid Hormone Receptors beta12014210.120 Why?
Nuclear Receptor Co-Repressor 112014280.110 Why?
Receptors, LDL220154920.110 Why?
Substrate Specificity2200917510.110 Why?
Hepacivirus1202113430.110 Why?
Consensus1202432000.110 Why?
Intestinal Mucosa5201530480.110 Why?
Panniculitis12014450.110 Why?
Liver Diseases3201813040.110 Why?
Body Composition4201724410.110 Why?
Glucagon-Like Peptide 1120163730.110 Why?
Phosphoproteins2201624450.110 Why?
Hydroxymethylglutaryl CoA Reductases22004640.110 Why?
Societies, Medical2201539550.110 Why?
Receptors, Thrombin120131300.110 Why?
Workflow120188590.110 Why?
Transcription Factors72023121280.110 Why?
Coma120174850.110 Why?
MicroRNAs3201537870.110 Why?
Natural Killer T-Cells120163190.110 Why?
Receptors, CXCR3120142400.100 Why?
Mucus120153460.100 Why?
Cross Reactions120158250.100 Why?
Cloning, Molecular2201241630.100 Why?
Coronavirus Infections2202031110.100 Why?
Kinetics3202062730.100 Why?
Inhibitory Concentration 50120134630.100 Why?
Pneumonia, Viral2202032330.100 Why?
Species Specificity2200724060.100 Why?
Double-Blind Method32019124260.100 Why?
Diabetes Mellitus, Type 232023122350.100 Why?
Inhalation Exposure120154320.100 Why?
Estrogens1201915280.100 Why?
Adipocytes3201911950.100 Why?
Signal Transduction92020236000.100 Why?
Aldehyde Dehydrogenase120121460.090 Why?
TOR Serine-Threonine Kinases3201920560.090 Why?
Estradiol1201919470.090 Why?
Gastrointestinal Diseases1202012040.090 Why?
Chemotaxis, Leukocyte120146570.090 Why?
Hepatitis C1202115960.090 Why?
Receptors, G-Protein-Coupled1201912450.090 Why?
Models, Molecular3200753830.090 Why?
Malnutrition120176290.090 Why?
Feeding Behavior2202132080.090 Why?
Fatty Acids, Nonesterified220133930.090 Why?
Receptors, Estrogen1201922420.090 Why?
Sterol Regulatory Element Binding Proteins12010250.090 Why?
Metabolic Diseases120176860.090 Why?
Blotting, Western2200950190.090 Why?
Crosses, Genetic220097520.090 Why?
Adipose Tissue4201533140.090 Why?
Induced Pluripotent Stem Cells1202118840.080 Why?
Gene Targeting120138400.080 Why?
Liver Function Tests220145270.080 Why?
Fenofibrate12010870.080 Why?
Hepatocyte Nuclear Factor 4120101260.080 Why?
Gaucher Disease120101100.080 Why?
Drug Therapy, Combination1201963080.080 Why?
Iodide Peroxidase120112950.080 Why?
Hydrogen-Ion Concentration2201524760.080 Why?
Apoptosis1200595070.080 Why?
Membrane Proteins4202278500.080 Why?
Cell Membrane3201036350.080 Why?
Base Sequence22012124050.080 Why?
Protein Folding220098680.080 Why?
Osmolar Concentration120096550.080 Why?
Disease Models, Animal42021183210.070 Why?
Clinical Trials as Topic1202480370.070 Why?
Cells, Cultured32014189650.070 Why?
Chylomicrons12007260.070 Why?
Biliary Tract120081370.070 Why?
Microscopy, Electron2200925430.070 Why?
Tissue Distribution3200722700.070 Why?
Steroid Hydroxylases22004930.070 Why?
Glucose Clamp Technique120082620.070 Why?
DNA Primers1201228230.070 Why?
Lipoprotein-X1200750.070 Why?
Phosphorylation2202182900.070 Why?
Fibrosis1201420730.070 Why?
Endoplasmic Reticulum2201011320.070 Why?
Scavenger Receptors, Class B12007850.070 Why?
Multiprotein Complexes1201311070.070 Why?
Magnetic Resonance Spectroscopy1201736790.070 Why?
Gallbladder220053080.070 Why?
Oligonucleotide Array Sequence Analysis3201037960.070 Why?
Cell Transformation, Neoplastic1201628380.070 Why?
Norepinephrine120098980.070 Why?
Two-Hybrid System Techniques120074630.070 Why?
Pulmonary Surfactants120071690.070 Why?
Receptors, Cytoplasmic and Nuclear220088530.060 Why?
Temperature2201122270.060 Why?
T-Lymphocyte Subsets1201418140.060 Why?
Cardiovascular Diseases42016156390.060 Why?
Adaptor Proteins, Signal Transducing1201628980.060 Why?
Logistic Models12020132720.060 Why?
Ligands2202332740.060 Why?
Female1920203961740.060 Why?
Lactation120083910.060 Why?
Cholesterol, Dietary120052240.060 Why?
Reverse Transcriptase Polymerase Chain Reaction2200945650.060 Why?
Amino Acid Motifs120079240.060 Why?
Bile Canaliculi12004120.060 Why?
Bezafibrate12004140.060 Why?
Stearoyl-CoA Desaturase12005840.060 Why?
Enzyme-Linked Immunosorbent Assay1201238010.060 Why?
Nerve Tissue Proteins1201743990.060 Why?
CHO Cells2201013730.060 Why?
Aspartate Aminotransferases120064160.060 Why?
RNA, Messenger62011127720.060 Why?
HEK293 Cells1201342620.060 Why?
L-Lactate Dehydrogenase120054110.060 Why?
Cell Culture Techniques2200916490.060 Why?
Infusions, Parenteral120043950.060 Why?
Cholestasis120073850.060 Why?
Cricetinae2201024130.050 Why?
Gene Expression Profiling2201095250.050 Why?
Cholestasis, Intrahepatic12003750.050 Why?
Tumor Suppressor Proteins1201327930.050 Why?
DNA, Complementary1200619840.050 Why?
Enzyme Induction220174560.050 Why?
Electrophoresis, Polyacrylamide Gel1200517240.050 Why?
Phospholipases A2, Calcium-Independent12022120.050 Why?
Blood Platelets1201324640.050 Why?
Prognosis22013299050.050 Why?
Molecular Structure1200718810.050 Why?
Organ Specificity1200719660.050 Why?
Cell Line32019155450.050 Why?
Biopsy1201467680.050 Why?
Adaptation, Physiological1200913100.050 Why?
Cholesterol, VLDL12002700.050 Why?
Caveolins120021020.050 Why?
NG-Nitroarginine Methyl Ester120022620.050 Why?
Amino Acid Substitution1200617420.050 Why?
Microscopy, Fluorescence1200926260.050 Why?
Intestinal Absorption120034000.050 Why?
Rats, Sprague-Dawley3201581140.050 Why?
Down-Regulation2200829270.050 Why?
Homozygote1200617740.050 Why?
Cerebral Ventricles120045500.050 Why?
X-Ray Diffraction120024130.050 Why?
Cattle1200738010.050 Why?
Adrenergic Agonists12021560.050 Why?
Point Mutation1200615910.050 Why?
Crystallization120025180.050 Why?
Organ Size2201922600.050 Why?
Aging1202087230.050 Why?
Saccharomyces cerevisiae Proteins1201018360.050 Why?
Acyltransferases120223050.040 Why?
DNA-Binding Proteins2200896000.040 Why?
Middle Aged720202230350.040 Why?
Isoenzymes1200516880.040 Why?
Lipase120223200.040 Why?
Intracellular Space120211980.040 Why?
Research Design1201662050.040 Why?
Consultants12020570.040 Why?
Infusions, Intravenous1200422270.040 Why?
Protein Structure, Secondary1200212110.040 Why?
9,10-Dimethyl-1,2-benzanthracene12019580.040 Why?
Nuclear Proteins2201857910.040 Why?
Growth Differentiation Factors12020990.040 Why?
Gene Expression Regulation, Neoplastic1201586130.040 Why?
Evidence-Based Medicine2201436890.040 Why?
Diagnosis, Differential12014129750.040 Why?
Risk Factors32020748370.040 Why?
Treatment Outcome32024652030.040 Why?
Allosteric Regulation120204250.040 Why?
Liver Transplantation2201424170.040 Why?
Drug Resistance1200515920.040 Why?
Risk Assessment12020242720.040 Why?
Protein Transport1200419390.040 Why?
Protein Conformation1200639470.040 Why?
RNA-Binding Proteins1200718830.040 Why?
Macrophages3201057750.040 Why?
Cytosol120018850.040 Why?
United States42020729180.040 Why?
Activating Transcription Factor 412018860.040 Why?
Chromosome Mapping1200646160.040 Why?
Fructokinases1201760.040 Why?
Phosphatidylinositol 3-Kinase120191250.040 Why?
New York120208800.040 Why?
Inflammation12018108580.040 Why?
Crystallography, X-Ray1200219470.040 Why?
MAP Kinase Kinase 4120181470.040 Why?
tRNA Methyltransferases12017500.040 Why?
Sodium Benzoate12017140.040 Why?
Ursodeoxycholic Acid12017810.040 Why?
Serine120218280.040 Why?
Disease Progression12014136140.030 Why?
Phenylacetates120171120.030 Why?
Liver Regeneration120192130.030 Why?
Haplorhini120185200.030 Why?
Mice, Inbred ICR120173610.030 Why?
Rats32015237180.030 Why?
Genetic Predisposition to Disease32017180750.030 Why?
Pulmonary Gas Exchange120183890.030 Why?
Circadian Rhythm1200825930.030 Why?
Gene Expression Regulation, Developmental1200736060.030 Why?
Zebrafish2201930350.030 Why?
Aged420201711700.030 Why?
Diethylnitrosamine12015450.030 Why?
Glutamates120173840.030 Why?
Deficiency Diseases12016740.030 Why?
Weight Gain2201923560.030 Why?
Receptors, TNF-Related Apoptosis-Inducing Ligand12015580.030 Why?
Digestion12015530.030 Why?
Gastrointestinal Hormones120151010.030 Why?
Endocrine System120151110.030 Why?
Sex Factors32019106110.030 Why?
p38 Mitogen-Activated Protein Kinases120186930.030 Why?
Hydrophobic and Hydrophilic Interactions220083900.030 Why?
Viscosity120153340.030 Why?
Elastic Modulus120152080.030 Why?
Embolism, Cholesterol12013320.030 Why?
Orphan Nuclear Receptors12014630.030 Why?
Transfection1200157390.030 Why?
Cytochrome P-450 CYP3A120141170.030 Why?
Binding Sites1200260020.030 Why?
History, 20th Century1202127620.030 Why?
Diarrhea1202013150.030 Why?
Tumor Burden1201918890.030 Why?
HCT116 Cells120133990.030 Why?
Hep G2 Cells120133780.030 Why?
ROC Curve1202036140.030 Why?
Adult420192231100.030 Why?
Retinal Dehydrogenase12012780.020 Why?
Cell Proliferation22019104310.020 Why?
Hepatitis, Autoimmune120141730.020 Why?
Protein Processing, Post-Translational1201919610.020 Why?
Receptors, Retinoic Acid120122290.020 Why?
Iceland120111830.020 Why?
Transcriptional Activation1201717420.020 Why?
Animals, Genetically Modified1201615620.020 Why?
Regression Analysis1202063240.020 Why?
Dose-Response Relationship, Drug12003107370.020 Why?
Platelet Aggregation120137690.020 Why?
Glucosylceramides12010270.020 Why?
Gene Expression2201975810.020 Why?
Pandemics2202087240.020 Why?
Food120157640.020 Why?
Chromosomes, Human, Pair 5120113860.020 Why?
Dietary Supplements1200334260.020 Why?
Sterol Regulatory Element Binding Protein 212010580.020 Why?
Brain12017271750.020 Why?
Adrenergic beta-Agonists120113450.020 Why?
Apoptosis Regulatory Proteins1201511500.020 Why?
Sterol Regulatory Element Binding Protein 1120101350.020 Why?
Escherichia coli1200242090.020 Why?
Analysis of Variance1201862080.020 Why?
Models, Animal1201621200.020 Why?
Time Factors32014401000.020 Why?
Amino Acid Sequence12021134000.020 Why?
Intestine, Small2200712160.020 Why?
Disease Susceptibility2200817890.020 Why?
Cricetulus120108070.020 Why?
Steroid 12-alpha-Hydroxylase1200890.020 Why?
Gastric Bypass120178200.020 Why?
Cholic Acids12008390.020 Why?
Liver Cirrhosis1201919610.020 Why?
Behavior, Animal1201618670.020 Why?
Linear Models1201858720.020 Why?
Virus Diseases120147200.020 Why?
Ketones120091830.020 Why?
3' Untranslated Regions120105140.020 Why?
Massachusetts1202088820.020 Why?
Introns120109650.020 Why?
Oligonucleotides, Antisense120104620.020 Why?
Ion Channels1201210440.020 Why?
Sequence Homology, Amino Acid1201127430.020 Why?
Phosphatidylcholine-Sterol O-Acyltransferase12007330.020 Why?
Fasting1201316070.020 Why?
Proto-Oncogene Proteins c-akt1201524540.020 Why?
Integrases120095200.020 Why?
Linkage Disequilibrium1201119960.020 Why?
Hospital Mortality1202053390.020 Why?
Enterocytes120072200.020 Why?
Blotting, Northern1200715460.020 Why?
Neoplasm Proteins1201835940.020 Why?
Transcription, Genetic1201975990.020 Why?
Inflammation Mediators1201418900.020 Why?
Incidence22016215090.010 Why?
Swine1201559860.010 Why?
Prenatal Exposure Delayed Effects1201725350.010 Why?
4-Chloro-7-nitrobenzofurazan12004210.010 Why?
Lysosomes120109320.010 Why?
Hyperglycemia1201313890.010 Why?
Receptor, Insulin120088380.010 Why?
Models, Biological2201094460.010 Why?
Dietary Carbohydrates120088960.010 Why?
Sterols12003630.010 Why?
Body Mass Index22011130420.010 Why?
Gastrointestinal Transit120031020.010 Why?
Detergents120022350.010 Why?
Genetic Loci1201126300.010 Why?
Antiviral Agents1201430680.010 Why?
RNA Interference1201028250.010 Why?
Proportional Hazards Models12016125290.010 Why?
Sensitivity and Specificity12016146440.010 Why?
Promoter Regions, Genetic1201257840.010 Why?
Nitric Oxide Synthase Type II120025120.010 Why?
Caveolin 1120022550.010 Why?
Hospitalization12020108040.010 Why?
Reproducibility of Results12018201350.010 Why?
RNA, Small Interfering1200934230.010 Why?
Severity of Illness Index12018158820.010 Why?
Thrombosis1201329530.010 Why?
Saccharomyces cerevisiae1201026770.010 Why?
Phenotype22010167140.010 Why?
Nitric Oxide Synthase120029110.010 Why?
Nitric Oxide Synthase Type III120027070.010 Why?
Capillaries120027500.010 Why?
Serum Albumin120026740.010 Why?
Capillary Permeability120027700.010 Why?
Adenoviridae1200210920.010 Why?
Cohort Studies22011416770.010 Why?
Integrins120028380.010 Why?
Mutation12002302100.010 Why?
Magnetic Resonance Imaging12005365470.010 Why?
Microcirculation1200212820.010 Why?
Genome-Wide Association Study12015128030.010 Why?
Polymorphism, Single Nucleotide12015160400.010 Why?
Pregnancy12017302280.010 Why?
Aged, 80 and over12020594970.010 Why?
Immunohistochemistry12007110350.010 Why?
Prevalence12010158200.010 Why?
Enzyme Inhibitors1200237220.010 Why?
Retrospective Studies12020815440.010 Why?
Prospective Studies12016548040.010 Why?
Endothelium, Vascular1200244230.010 Why?
Genotype12004130270.010 Why?
Adolescent12017888080.000 Why?
Cell Line, Tumor12004170710.000 Why?
Lung12002100610.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.