Nuclear Respiratory Factor 1

"Nuclear Respiratory Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A transcription factor that controls the expression of variety of proteins including CYTOCHROME C and 5-AMINOLEVULINATE SYNTHETASE. It plays an important role in maintenance of the RESPIRATORY CHAIN of MITOCHONDRIA.

Descriptor ID

D051266

MeSH Number(s)

D12.776.260.615.500

D12.776.930.618.500

Concept/Terms

Nuclear Respiratory Factor 1

Below are MeSH descriptors whose meaning is more general than "Nuclear Respiratory Factor 1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Nuclear Respiratory Factors [D12.776.260.615]
Nuclear Respiratory Factor 1 [D12.776.260.615.500]
Transcription Factors [D12.776.930]
Nuclear Respiratory Factors [D12.776.930.618]
Nuclear Respiratory Factor 1 [D12.776.930.618.500]

Below are MeSH descriptors whose meaning is related to "Nuclear Respiratory Factor 1".

Below are MeSH descriptors whose meaning is more specific than "Nuclear Respiratory Factor 1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Nuclear Respiratory Factor 1" by people in Harvard Catalyst Profiles by year, and whether "Nuclear Respiratory Factor 1" was a major or minor topic of these publication.

Bar chart showing 15 publications over 14 distinct years, with a maximum of 2 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	0	1	1
2003	0	1	1
2007	0	1	1
2010	0	1	1
2011	0	1	1
2012	0	1	1
2014	0	1	1
2015	1	0	1
2017	2	0	2
2018	0	1	1
2019	0	1	1
2020	0	1	1
2021	0	1	1
2023	1	0	1

Below are the most recent publications written about "Nuclear Respiratory Factor 1" by people in Profiles.

Regulation and Functions of the ER-Associated Nrf1 Transcription Factor. Cold Spring Harb Perspect Biol. 2023 01 03; 15(1).

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Subtype-specific collaborative transcription factor networks are promoted by OCT4 in the progression of prostate cancer. Nat Commun. 2021 06 18; 12(1):3766.

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Carnitine palmitoyltransferase 1C contributes to progressive cellular senescence. Aging (Albany NY). 2020 04 14; 12(8):6733-6755.

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The Proteasome and Its Network: Engineering for Adaptability. Cold Spring Harb Perspect Biol. 2020 01 02; 12(1).

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DNA methylation reprograms cardiac metabolic gene expression in end-stage human heart failure. Am J Physiol Heart Circ Physiol. 2019 10 01; 317(4):H674-H684.

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Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity. Leukemia. 2018 09; 32(9):1948-1957.

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NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis. Cell. 2017 Nov 16; 171(5):1094-1109.e15.

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The p97 Inhibitor CB-5083 Is a Unique Disrupter of Protein Homeostasis in Models of Multiple Myeloma. Mol Cancer Ther. 2017 11; 16(11):2375-2386.

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Inhibition of the Proteasome ß2 Site Sensitizes Triple-Negative Breast Cancer Cells to ß5 Inhibitors and Suppresses Nrf1 Activation. Cell Chem Biol. 2017 Feb 16; 24(2):218-230.

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Reply to Vangala et al.: Complete inhibition of the proteasome reduces new proteasome production by causing Nrf1 aggregation. Curr Biol. 2016 09 26; 26(18):R836-R837.

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