tRNA Methyltransferases

"tRNA Methyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Enzymes that catalyze the S-adenosyl-L-methionine-dependent methylation of ribonucleotide bases within a transfer RNA molecule. EC 2.1.1.

Descriptor ID

D012359

MeSH Number(s)

D08.811.913.555.500.925

Concept/Terms

tRNA Methyltransferases

Below are MeSH descriptors whose meaning is more general than "tRNA Methyltransferases".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Transferases [D08.811.913]
One-Carbon Group Transferases [D08.811.913.555]
Methyltransferases [D08.811.913.555.500]
tRNA Methyltransferases [D08.811.913.555.500.925]

Below are MeSH descriptors whose meaning is related to "tRNA Methyltransferases".

Below are MeSH descriptors whose meaning is more specific than "tRNA Methyltransferases".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "tRNA Methyltransferases" by people in Harvard Catalyst Profiles by year, and whether "tRNA Methyltransferases" was a major or minor topic of these publication.

Bar chart showing 32 publications over 17 distinct years, with a maximum of 5 publications in 2016 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	0	1	1
2006	0	1	1
2008	0	3	3
2009	1	1	2
2010	0	1	1
2011	0	1	1
2013	1	1	2
2014	0	1	1
2015	0	1	1
2016	0	5	5
2017	0	1	1
2019	2	2	4
2020	3	2	5
2021	1	0	1
2022	0	1	1
2023	1	0	1

Below are the most recent publications written about "tRNA Methyltransferases" by people in Profiles.

Crosstalk between the tRNA methyltransferase Trm1 and RNA chaperone La influences eukaryotic tRNA maturation. J Biol Chem. 2023 11; 299(11):105326.

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Genotypic and phenotypic spectrum of infantile liver failure due to pathogenic TRMU variants. Genet Med. 2023 06; 25(6):100314.

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METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation. Mol Cell. 2021 08 19; 81(16):3323-3338.e14.

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A semi-quantitative pull-down assay to study tRNA substrate specificity of modification enzymes. Methods Enzymol. 2021; 658:359-377.

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Metabolic shift underlies recovery in reversible infantile respiratory chain deficiency. EMBO J. 2020 12 01; 39(23):e105364.

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DALRD3 encodes a protein mutated in epileptic encephalopathy that targets arginine tRNAs for 3-methylcytosine modification. Nat Commun. 2020 05 19; 11(1):2510.

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2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations. Nat Commun. 2020 03 20; 11(1):1509.

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tRNA 2'-O-methylation by a duo of TRM7/FTSJ1 proteins modulates small RNA silencing in Drosophila. Nucleic Acids Res. 2020 02 28; 48(4):2050-2072.

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An intellectual disability-associated missense variant in TRMT1 impairs tRNA modification and reconstitution of enzymatic activity. Hum Mutat. 2020 03; 41(3):600-607.

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Genetic susceptibility, lifestyle intervention and glycemic changes among women with prior gestational diabetes. Clin Nutr. 2020 07; 39(7):2144-2150.

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