Cholic Acids

"Cholic Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The 3 alpha,7 alpha,12 alpha-trihydroxy-5 beta-cholanic acid family of bile acids in man, usually conjugated with glycine or taurine. They act as detergents to solubilize fats for intestinal absorption, are reabsorbed by the small intestine, and are used as cholagogues and choleretics.

Descriptor ID

D002793

MeSH Number(s)

D04.808.105.225

D04.808.221.430

Concept/Terms

Cholic Acids

Below are MeSH descriptors whose meaning is more general than "Cholic Acids".

Chemicals and Drugs [D]
Polycyclic Compounds [D04]
Steroids [D04.808]
Bile Acids and Salts [D04.808.105]
Cholic Acids [D04.808.105.225]
Cholanes [D04.808.221]
Cholic Acids [D04.808.221.430]

Below are MeSH descriptors whose meaning is related to "Cholic Acids".

Below are MeSH descriptors whose meaning is more specific than "Cholic Acids".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cholic Acids" by people in Harvard Catalyst Profiles by year, and whether "Cholic Acids" was a major or minor topic of these publication.

Bar chart showing 24 publications over 15 distinct years, with a maximum of 3 publications in 1994 and 1995

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	0	3	3
1995	0	3	3
1996	0	1	1
1997	1	1	2
1998	0	1	1
1999	0	1	1
2000	1	1	2
2001	0	1	1
2003	0	2	2
2008	0	1	1
2012	0	1	1
2013	0	2	2
2014	1	1	2
2019	1	0	1
2021	1	0	1

Below are the most recent publications written about "Cholic Acids" by people in Profiles.

Cyp2c-deficiency depletes muricholic acids and protects against high-fat diet-induced obesity in male mice but promotes liver damage. Mol Metab. 2021 11; 53:101326.

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Deciphering the Role of Intramolecular Networking in Cholic Acid-Peptide Conjugates on the Lipopolysaccharide Surface in Combating Gram-Negative Bacterial Infections. J Med Chem. 2019 02 28; 62(4):1875-1886.

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FXR/TGR5 Dual Agonist Prevents Progression of Nephropathy in Diabetes and Obesity. J Am Soc Nephrol. 2018 01; 29(1):118-137.

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End-Site-Specific Conjugation of Enoxaparin and Tetradeoxycholic Acid Using Nonenzymatic Glycosylation for Oral Delivery. J Med Chem. 2016 12 08; 59(23):10520-10529.

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Cyp2c70 is responsible for the species difference in bile acid metabolism between mice and humans. J Lipid Res. 2016 12; 57(12):2130-2137.

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Intestine-selective farnesoid X receptor inhibition improves obesity-related metabolic dysfunction. Nat Commun. 2015 Dec 15; 6:10166.

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Differential antigenic protein recovery from Taenia solium cyst tissues using several detergents. Mol Biochem Parasitol. 2015 Jul; 202(1):22-8.

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Comparative proteomic and transcriptomic profile of Staphylococcus epidermidis biofilms grown in glucose-enriched medium. Talanta. 2015 Jan; 132:705-12.

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Influence of pH on extracellular matrix preservation during lung decellularization. Tissue Eng Part C Methods. 2014 Dec; 20(12):1028-36.

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Perfusion decellularization of human and porcine lungs: bringing the matrix to clinical scale. J Heart Lung Transplant. 2014 Mar; 33(3):298-308.

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