Nuclear Receptor Co-Repressor 1

"Nuclear Receptor Co-Repressor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A nuclear protein that regulates the expression of genes involved in a diverse array of processes related to metabolism and reproduction. The protein contains three nuclear receptor interaction domains and three repressor domains and is closely-related in structure to NUCLEAR RECEPTOR CO-REPRESSOR 2.

Descriptor ID

D056971

MeSH Number(s)

D12.776.930.700.625.374

Concept/Terms

Nuclear Receptor Co-Repressor 1

Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Co-Repressor 1".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Transcription Factors [D12.776.930]
Repressor Proteins [D12.776.930.700]
Co-Repressor Proteins [D12.776.930.700.625]
Nuclear Receptor Co-Repressor 1 [D12.776.930.700.625.374]

Below are MeSH descriptors whose meaning is related to "Nuclear Receptor Co-Repressor 1".

Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Co-Repressor 1".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Nuclear Receptor Co-Repressor 1" by people in Harvard Catalyst Profiles by year, and whether "Nuclear Receptor Co-Repressor 1" was a major or minor topic of these publication.

Bar chart showing 27 publications over 17 distinct years, with a maximum of 4 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	2	2
1999	0	2	2
2000	0	1	1
2002	0	1	1
2003	0	1	1
2004	0	1	1
2005	0	1	1
2007	0	3	3
2008	0	1	1
2009	0	1	1
2010	1	0	1
2011	2	0	2
2012	1	0	1
2013	4	0	4
2014	3	0	3
2018	0	1	1
2022	1	0	1

Below are the most recent publications written about "Nuclear Receptor Co-Repressor 1" by people in Profiles.

Balanced control of thermogenesis by nuclear receptor corepressors in brown adipose tissue. Proc Natl Acad Sci U S A. 2022 08 16; 119(33):e2205276119.

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HDAC3 ensures stepwise epidermal stratification via NCoR/SMRT-reliant mechanisms independent of its histone deacetylase activity. Genes Dev. 2020 07 01; 34(13-14):973-988.

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NCOR1 Orchestrates Transcriptional Landscapes and Effector Functions of CD4+ T Cells. Front Immunol. 2020; 11:579.

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Differential expression of vitamin D associated genes in the aorta of coronary artery disease patients with and without rheumatoid arthritis. PLoS One. 2018; 13(8):e0202346.

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Rev-erba dynamically modulates chromatin looping to control circadian gene transcription. Science. 2018 03 16; 359(6381):1274-1277.

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Distinct role of nuclear receptor corepressor 1 regulated de novo fatty acids synthesis in liver regeneration and hepatocarcinogenesis in mice. Hepatology. 2018 03; 67(3):1071-1087.

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NCoR1-independent mechanism plays a role in the action of the unliganded thyroid hormone receptor. Proc Natl Acad Sci U S A. 2017 10 03; 114(40):E8458-E8467.

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Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells. Autophagy. 2017 Jan 02; 13(1):169-186.

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NCoR1 and SMRT play unique roles in thyroid hormone action in vivo. Mol Cell Biol. 2015 Feb; 35(3):555-65.

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Receptor-interacting protein 140 attenuates endoplasmic reticulum stress in neurons and protects against cell death. Nat Commun. 2014 Jul 28; 5:4487.

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