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Cholesterol 7-alpha-Hydroxylase

"Cholesterol 7-alpha-Hydroxylase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information
Definition  |  Details  |  More General Concepts  |  Related Concepts  |  More Specific Concepts
A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS.


publications
Timeline   |   Most Recent
This graph shows the total number of publications written about "Cholesterol 7-alpha-Hydroxylase" by people in Harvard Catalyst Profiles by year, and whether "Cholesterol 7-alpha-Hydroxylase" was a major or minor topic of these publication.
Bar chart showing 27 publications over 16 distinct years, with a maximum of 4 publications in 2002
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.