Harvard Catalyst Profiles

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Gokhan S. Hotamisligil, M.D., Ph.D.

Concepts (420)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Fatty Acid-Binding Proteins2820192953.820 Why?
Adipocytes31200811872.850 Why?
Insulin Resistance40201939541.970 Why?
Endoplasmic Reticulum11201011321.670 Why?
Obesity582015129331.650 Why?
Adipose Tissue40200933091.550 Why?
Tumor Necrosis Factor-alpha31200943411.530 Why?
Receptors, Tumor Necrosis Factor1820035811.190 Why?
Metabolic Diseases520176801.150 Why?
Inflammation232017107600.960 Why?
JNK Mitogen-Activated Protein Kinases620084380.940 Why?
Carrier Proteins13200549350.800 Why?
Insulin28201365930.780 Why?
Lipid Metabolism16201518960.730 Why?
Stress, Physiological8201014030.700 Why?
Propionates120191830.620 Why?
Glucose16201743450.600 Why?
Macrophages15201557580.570 Why?
Neoplasm Proteins11201536070.570 Why?
Glucagon120195310.560 Why?
Diabetes Mellitus, Type 2162013121420.530 Why?
Mitogen-Activated Protein Kinase 852008710.530 Why?
Leptin14201515950.520 Why?
Myelin P2 Protein32000200.500 Why?
Animals8820191682010.480 Why?
Arteriosclerosis6200510560.480 Why?
Mice652019813680.450 Why?
Receptor, Insulin1120088360.450 Why?
Proteins12200860300.420 Why?
GATA3 Transcription Factor420071540.420 Why?
Adiponectin6200611070.420 Why?
Phenylbutyrates32008720.410 Why?
Hormones, Ectopic22003370.400 Why?
Cell Differentiation102007115140.400 Why?
GATA2 Transcription Factor420051580.400 Why?
Mice, Obese1120154180.400 Why?
Diabetes Mellitus10201558350.390 Why?
Fatty Acids, Monounsaturated220131900.390 Why?
Liver11201375120.380 Why?
Immunity120179940.380 Why?
Energy Metabolism3201928780.380 Why?
Unfolded Protein Response220102340.370 Why?
Thiazolidinediones320094600.350 Why?
Atherosclerosis6201334000.340 Why?
Taurochenodeoxycholic Acid22007350.340 Why?
Mitogen-Activated Protein Kinase 922006290.330 Why?
Trans-Activators3200528520.330 Why?
Overnutrition12008250.320 Why?
Receptors, Tumor Necrosis Factor, Type I1220062540.320 Why?
Adipose Tissue, Brown320057620.310 Why?
Mice, Inbred C57BL252019221150.300 Why?
Nerve Tissue Proteins5200244080.300 Why?
CCAAT-Enhancer-Binding Protein-alpha220061300.300 Why?
Antigens, CD10200339980.290 Why?
Homeostasis12200833210.280 Why?
Proteasome Endopeptidase Complex1201313200.270 Why?
Mice, Knockout192015143890.270 Why?
Fatty Acids6200618080.260 Why?
Adipogenesis220063660.260 Why?
Intercellular Signaling Peptides and Proteins5200516500.260 Why?
Transcription Factors72008121160.260 Why?
Signal Transduction182017234160.250 Why?
Mammary Glands, Human120072020.250 Why?
Cholesterol5200729030.250 Why?
Mammary Glands, Animal120072720.250 Why?
PPAR gamma220054840.240 Why?
Hormones120088690.230 Why?
Lipolysis320002110.230 Why?
Mitogen-Activated Protein Kinases3200412420.230 Why?
DNA-Binding Proteins5200595860.230 Why?
Gene Expression Regulation122012118740.230 Why?
Apoptosis6201294760.230 Why?
Triglycerides8201324590.220 Why?
Cell Lineage3201525540.220 Why?
Glucose Tolerance Test6200611780.220 Why?
Tumor Suppressor Proteins4200828010.220 Why?
Hypothalamus120089990.210 Why?
Blood Glucose8200863900.210 Why?
Receptors, Cytoplasmic and Nuclear320058580.210 Why?
Hypertriglyceridemia120062930.210 Why?
Food220077680.210 Why?
Insulin Receptor Substrate Proteins620085570.210 Why?
Metabolic Networks and Pathways120077890.210 Why?
Gene Expression6200675680.200 Why?
Apolipoproteins E5200714430.200 Why?
Receptors, Tumor Necrosis Factor, Type II820063440.190 Why?
Mice, Transgenic11200995290.190 Why?
eIF-2 Kinase320081450.190 Why?
Cytokines4201773730.190 Why?
Cell Line112008155760.190 Why?
Protein Folding320108700.180 Why?
Fatty Liver120067870.170 Why?
Organ Specificity3201719640.170 Why?
Phosphorylation9200683110.170 Why?
Membrane Proteins4200778470.170 Why?
Blotting, Northern5200515450.170 Why?
Lipids8201333320.170 Why?
RNA, Messenger152009127580.170 Why?
Glycogen120192510.160 Why?
Mice, Mutant Strains4200717480.150 Why?
Interleukin-67200732060.140 Why?
Phosphoproteins5200424460.140 Why?
Neovascularization, Physiologic2201513490.140 Why?
Stearoyl-CoA Desaturase22008850.140 Why?
Humans6120197606170.130 Why?
Cells, Cultured92012189370.130 Why?
Biological Evolution2201710700.130 Why?
Cell Communication2201716540.130 Why?
3T3 Cells6200610850.130 Why?
Adenylate Kinase220061020.130 Why?
Body Composition2200324260.130 Why?
Body Weight6200646140.130 Why?
Promoter Regions, Genetic5200657800.130 Why?
Receptors, Adrenergic, beta320012420.130 Why?
I-kappa B Kinase220082490.130 Why?
Polymorphism, Genetic1200642420.130 Why?
Mast Cells2201513920.130 Why?
Hypercholesterolemia1200211410.130 Why?
Plasminogen Activator Inhibitor 1320032770.120 Why?
Cryoprotective Agents119961280.120 Why?
Ethylene Glycols119961900.120 Why?
Epithelial Cells1200736720.120 Why?
Cell Membrane3200236800.120 Why?
Organ Size3200422520.110 Why?
Reverse Transcriptase Polymerase Chain Reaction4200645700.110 Why?
Models, Biological5200894610.110 Why?
Adaptive Immunity120177240.100 Why?
Weight Gain2201923500.100 Why?
Muscle Proteins1199711520.100 Why?
Immune System120177910.100 Why?
Stem Cell Factor120121950.100 Why?
Bone Marrow Transplantation3200826900.100 Why?
Resistin220031720.090 Why?
Oocytes1199611660.090 Why?
Cytoskeleton1199611700.090 Why?
Cryopreservation119967280.090 Why?
Nerve Growth Factor220031580.090 Why?
Male3920193603580.090 Why?
Thinness320064800.090 Why?
Aorta4201520410.090 Why?
Inflammation Mediators2201718840.090 Why?
Immunoblotting2200516460.090 Why?
Dietary Fats3201319950.090 Why?
Receptors, Adrenergic, beta-322000620.090 Why?
Blotting, Western6201250340.090 Why?
Muscle, Skeletal5200849470.090 Why?
Multiprotein Complexes2200811180.090 Why?
Protein Isoforms2200616970.080 Why?
Chemokine CXCL512009270.080 Why?
Dairy Products120134900.080 Why?
Genes, Reporter2200515250.080 Why?
Retinopathy of Prematurity120144390.080 Why?
Cromolyn Sodium12009780.080 Why?
Rats52005237170.080 Why?
HIV-11200668580.080 Why?
Diet7201380480.070 Why?
Transcription, Genetic5200675830.070 Why?
Ligands2200832680.070 Why?
Hyperinsulinism320084000.070 Why?
Body Fat Distribution120082450.070 Why?
Mutation82007300160.070 Why?
3T3-L1 Cells120072090.070 Why?
Lipogenesis120082140.070 Why?
C-Reactive Protein4200738220.070 Why?
Hepatocyte Nuclear Factor 3-alpha120071640.070 Why?
Female2620193921480.060 Why?
Chemokine CCL2120086020.060 Why?
Receptors, HIV120061580.060 Why?
Multiple Birth Offspring12005220.060 Why?
Eukaryotic Initiation Factor-2120061810.060 Why?
Proto-Oncogene Proteins c-kit120097270.060 Why?
Immunity, Innate1201730450.060 Why?
HIV-Associated Lipodystrophy Syndrome120061380.060 Why?
Orphan Nuclear Receptors12005630.060 Why?
Tunicamycin120041080.060 Why?
NF-kappa B2200524810.060 Why?
Recombinant Fusion Proteins2200537300.060 Why?
CCAAT-Enhancer-Binding Protein-beta120051020.060 Why?
Protein Tyrosine Phosphatases120064570.060 Why?
Mitochondrial Proteins220009740.060 Why?
Prostaglandin-Endoperoxide Synthases120053180.060 Why?
Body Mass Index92005129430.060 Why?
Mesentery120042020.060 Why?
Luciferases120057120.060 Why?
Reference Values4200349190.050 Why?
Genes, Tumor Suppressor1200810560.050 Why?
Tissue Distribution2200522610.050 Why?
Nitric Oxide Synthase Type II120055170.050 Why?
Protein Binding2200693450.050 Why?
CD40 Ligand120055210.050 Why?
Diabetes Mellitus, Experimental1200911170.050 Why?
Mice, Congenic12002970.050 Why?
Cardiovascular Diseases22006154980.050 Why?
Immunosorbent Techniques120021740.050 Why?
Cyclooxygenase 2120055960.050 Why?
Phenotype32006165710.050 Why?
Endothelium, Vascular2201244330.050 Why?
Biphenyl Compounds1200710070.050 Why?
Enzyme Activation2200635910.050 Why?
CHO Cells1200513870.050 Why?
Base Sequence22006124210.050 Why?
Microscopy, Electron1200525610.050 Why?
Diet, Fat-Restricted120043290.050 Why?
Tyrosine3200114400.050 Why?
Nitric Oxide Synthase120059080.050 Why?
Premenopause2199710380.050 Why?
Crosses, Genetic120037500.050 Why?
Blood Specimen Collection120032380.050 Why?
Encephalomyelitis, Autoimmune, Experimental120078230.050 Why?
Gene Expression Regulation, Enzymologic1200611690.050 Why?
Isoenzymes1200616870.050 Why?
Blotting, Southern120027770.050 Why?
Multienzyme Complexes120056660.050 Why?
T-Lymphocytes, Helper-Inducer120079740.050 Why?
AMP-Activated Protein Kinases120055970.050 Why?
Precipitin Tests120028130.050 Why?
Disease Models, Animal42006182210.050 Why?
Benzophenones12001570.050 Why?
Indicators and Reagents120024600.050 Why?
Cricetinae1200524240.050 Why?
Myeloid Cells120068230.050 Why?
Chemotaxis220155980.050 Why?
Protein Biosynthesis2199921000.050 Why?
Sirolimus1200815330.050 Why?
Cell Adhesion Molecules1200716020.050 Why?
Uncoupling Agents12000460.050 Why?
Haptoglobins120021650.050 Why?
ADAM Proteins120022380.040 Why?
Reproductive Techniques, Assisted120054960.040 Why?
Hepatocytes1200712310.040 Why?
Metalloendopeptidases120023930.040 Why?
HIV Infections22006173370.040 Why?
Nutritional Status1200815960.040 Why?
Biological Transport1200520890.040 Why?
Gastric Bypass120088180.040 Why?
Fatty Acids, Unsaturated120035400.040 Why?
Genetic Markers1200626010.040 Why?
Hypoglycemic Agents2200430850.040 Why?
Proto-Oncogene Proteins c-akt1200824560.040 Why?
Eating2200615350.040 Why?
Binding Sites1200860510.040 Why?
Hyperlipoproteinemia Type II120043950.040 Why?
Cell Line, Tumor22006169670.040 Why?
Drug Interactions1200414150.040 Why?
Interleukin-21200618870.040 Why?
In Situ Nick-End Labeling120006130.040 Why?
Leukocytes, Mononuclear1200618350.040 Why?
Lymphocyte Activation2200754630.040 Why?
TOR Serine-Threonine Kinases1200820570.040 Why?
Dendritic Cells2200727220.040 Why?
Oxygen2201442260.040 Why?
Ion Channels2200010390.040 Why?
Vascular Diseases1200711600.040 Why?
Social Behavior1200511350.040 Why?
Lipoproteins, HDL120036750.040 Why?
Life Style4200539040.040 Why?
Zinc Fingers120005780.040 Why?
Mutagenesis, Site-Directed1200116920.040 Why?
Up-Regulation3200241170.040 Why?
Models, Molecular1200854330.040 Why?
Asthma2200762330.040 Why?
Neurons2200894380.040 Why?
Antiretroviral Therapy, Highly Active1200618940.040 Why?
Adaptor Proteins, Signal Transducing1200828950.040 Why?
Cloning, Molecular1200341720.040 Why?
Glucose Transporter Type 4119972400.040 Why?
Time Factors52006399130.040 Why?
Blood Pressure1201384720.040 Why?
Hypersensitivity1200611670.030 Why?
Body Temperature120007800.030 Why?
Absorptiometry, Photon1200317380.030 Why?
Actins3200220500.030 Why?
Odds Ratio2200696430.030 Why?
Oxidative Stress1200831130.030 Why?
Molecular Sequence Data22007176290.030 Why?
Longevity1200410640.030 Why?
Pyrazoles1200720080.030 Why?
Ethylene Glycol11996310.030 Why?
Cold Temperature120007840.030 Why?
Regression Analysis2199763380.030 Why?
Cyclic AMP1200014630.030 Why?
Kinetics1200463700.030 Why?
Rats, Zucker119961310.030 Why?
Sphingomyelin Phosphodiesterase11996820.030 Why?
Structure-Activity Relationship1200130740.030 Why?
Monosaccharide Transport Proteins119974360.030 Why?
Middle Aged1720132205840.030 Why?
PPAR delta12015400.030 Why?
Prospective Studies82013543600.030 Why?
Mice, Inbred BALB C1200461880.030 Why?
Exercise2200358860.030 Why?
Feces1200214900.030 Why?
Cytoprotection120152000.030 Why?
DNA Primers1199928170.030 Why?
Gene Deletion1200226610.030 Why?
Models, Genetic1200534310.030 Why?
Protein Structure, Tertiary1200137920.030 Why?
Myocardial Ischemia1200521100.030 Why?
Membrane Transport Proteins1200010340.030 Why?
Islets of Langerhans1200013400.030 Why?
Cell Survival2201557800.030 Why?
Adult1420062209690.030 Why?
Interleukin-12220065770.030 Why?
Down-Regulation1200129150.030 Why?
Fatty Acids, Omega-31200313900.030 Why?
Thiazoles1200115170.030 Why?
Pancreas1200016900.030 Why?
Hydrogenation12013200.030 Why?
Adaptation, Physiological1200013000.030 Why?
CD4-Positive T-Lymphocytes1200643660.030 Why?
Gene Targeting119968370.030 Why?
Cohort Studies52007414570.030 Why?
Disease Progression22007134950.030 Why?
T-Lymphocytes22007101750.030 Why?
Serine119968300.020 Why?
Trans Fatty Acids120131550.020 Why?
Genotype12006129780.020 Why?
Feeding Behavior1200331820.020 Why?
Weight Loss1200226820.020 Why?
DNA1200571960.020 Why?
Repressor Proteins1200129850.020 Why?
Cell Death1201516770.020 Why?
C-Peptide220034400.020 Why?
Interleukin-12200612480.020 Why?
Sex Characteristics1200026370.020 Why?
Nuclear Proteins1200457890.020 Why?
Diet, Atherogenic12009920.020 Why?
Receptors, Leptin220013500.020 Why?
Radioimmunoassay220018610.020 Why?
Case-Control Studies52007221480.020 Why?
Phospholipids120137860.020 Why?
Microscopy, Fluorescence1199626390.020 Why?
Glucose Clamp Technique120082620.020 Why?
Fluorescent Dyes1199619010.020 Why?
Retinal Vessels120148520.020 Why?
Recombinant Proteins1199765200.020 Why?
Anthropometry2200413380.020 Why?
Stem Cells1200035160.020 Why?
Thrombosis1200129430.020 Why?
Lymphocyte Culture Test, Mixed120065080.020 Why?
Protein Tyrosine Phosphatase, Non-Receptor Type 112006960.020 Why?
I-kappa B Proteins120062110.020 Why?
Injections, Intraperitoneal120064120.020 Why?
Child, Preschool12008421880.020 Why?
Phosphoprotein Phosphatases120063280.020 Why?
Antineoplastic Agents12008136350.020 Why?
E-Selectin120075770.010 Why?
Cross-Sectional Studies52005260490.010 Why?
Aging2200186990.010 Why?
Vascular Cell Adhesion Molecule-1120076910.010 Why?
Genetic Predisposition to Disease12006178780.010 Why?
Drug Evaluation, Preclinical1200913330.010 Why?
Risk Factors62013741150.010 Why?
Follow-Up Studies42008390630.010 Why?
Neovascularization, Pathologic1201426440.010 Why?
Immunoprecipitation120068760.010 Why?
Adoptive Transfer120068180.010 Why?
RNA Interference1201228300.010 Why?
Cholesterol, LDL1201323790.010 Why?
Quality of Life12005133470.010 Why?
Intercellular Adhesion Molecule-11200711280.010 Why?
Psychology120053560.010 Why?
Myocardial Infarction12004114590.010 Why?
Respiratory Mucosa120064380.010 Why?
Aged820131690420.010 Why?
Interleukin-41200611460.010 Why?
Bronchi120068460.010 Why?
Clenbuterol1200190.010 Why?
Organic Anion Transporters120021010.010 Why?
Fatty Acids, Omega-6120032250.010 Why?
Antigen Presentation1200712500.010 Why?
Dobutamine120011160.010 Why?
Dioxoles12001950.010 Why?
Isoproterenol120013970.010 Why?
Cholesterol Esters12001730.010 Why?
Eicosanoids120032820.010 Why?
Foam Cells12001680.010 Why?
Protein Kinase C1200612020.010 Why?
Adrenergic alpha-Agonists120011770.010 Why?
Th2 Cells1200610560.010 Why?
Suppressor of Cytokine Signaling Proteins120011780.010 Why?
Oxidation-Reduction1200622310.010 Why?
Adrenergic beta-Agonists120013460.010 Why?
Embryo, Mammalian1200616700.010 Why?
Cell Proliferation12015104320.010 Why?
Food Deprivation120001140.010 Why?
COS Cells1200111300.010 Why?
Multivariate Analysis22005120430.010 Why?
Solubility1200110890.010 Why?
Glycoproteins1200722000.010 Why?
Breast Neoplasms12007209880.010 Why?
Hyperphagia120001390.010 Why?
Confidence Intervals1200529250.010 Why?
Endothelial Cells1201235480.010 Why?
Menopause1200716450.010 Why?
Bone Marrow Cells1200624090.010 Why?
Spinal Cord1200718070.010 Why?
Norepinephrine120018980.010 Why?
Neoplasms12008221310.010 Why?
Cell Culture Techniques1200616620.010 Why?
Drug Administration Schedule1200648450.010 Why?
Postmenopause1200725110.010 Why?
Amino Acid Sequence12007134410.010 Why?
Energy Intake1200321320.010 Why?
Fibroblasts1200641370.010 Why?
Ceramides119962000.010 Why?
Risk1200796040.010 Why?
Peptide Fragments1200751100.010 Why?
United States32013722720.010 Why?
Temperature1199922230.010 Why?
Membrane Glycoproteins1200236880.010 Why?
Transforming Growth Factor beta1199919630.010 Why?
Socioeconomic Factors1200577980.010 Why?
Biopsy1200167620.010 Why?
Health Personnel1200333330.010 Why?
Sex Factors12003105480.010 Why?
Predictive Value of Tests12005152510.000 Why?
Smoking1200190500.000 Why?
Brain12007271010.000 Why?
Aged, 80 and over12001588940.000 Why?
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Concepts (420)
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.