Harvard Catalyst Profiles

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Gokhan S. Hotamisligil, M.D., Ph.D.

Concepts (420)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Fatty Acid-Binding Proteins2820192963.850 Why?
Adipocytes31200811792.880 Why?
Insulin Resistance40201939601.990 Why?
Endoplasmic Reticulum11201011351.690 Why?
Obesity582015129151.660 Why?
Adipose Tissue40200932931.560 Why?
Tumor Necrosis Factor-alpha31200943571.540 Why?
Receptors, Tumor Necrosis Factor1820035841.190 Why?
Metabolic Diseases520176851.150 Why?
Inflammation232017107570.970 Why?
JNK Mitogen-Activated Protein Kinases620084440.950 Why?
Carrier Proteins13200549380.800 Why?
Insulin28201365920.790 Why?
Lipid Metabolism16201519020.740 Why?
Stress, Physiological8201013950.710 Why?
Propionates120191820.620 Why?
Glucose16201743610.610 Why?
Macrophages15201557450.570 Why?
Neoplasm Proteins11201536130.570 Why?
Glucagon120195320.560 Why?
Mitogen-Activated Protein Kinase 852008740.530 Why?
Diabetes Mellitus, Type 2162013122810.530 Why?
Leptin14201515900.520 Why?
Myelin P2 Protein32000200.500 Why?
Animals8820191679400.490 Why?
Arteriosclerosis6200510640.480 Why?
Mice652019812160.460 Why?
Receptor, Insulin1120088360.450 Why?
Proteins12200860300.430 Why?
GATA3 Transcription Factor420071520.420 Why?
Adiponectin6200611150.420 Why?
Phenylbutyrates32008720.410 Why?
Hormones, Ectopic22003370.410 Why?
Cell Differentiation102007114800.410 Why?
GATA2 Transcription Factor420051580.400 Why?
Mice, Obese1120154200.400 Why?
Diabetes Mellitus10201558840.390 Why?
Fatty Acids, Monounsaturated220131900.390 Why?
Liver11201375120.380 Why?
Immunity120179980.380 Why?
Energy Metabolism3201928690.380 Why?
Unfolded Protein Response220102330.380 Why?
Thiazolidinediones320094650.350 Why?
Taurochenodeoxycholic Acid22007350.340 Why?
Atherosclerosis6201335240.340 Why?
Mitogen-Activated Protein Kinase 922006310.330 Why?
Trans-Activators3200528610.330 Why?
Overnutrition12008250.320 Why?
Receptors, Tumor Necrosis Factor, Type I1220062560.320 Why?
Adipose Tissue, Brown320057550.320 Why?
Mice, Inbred C57BL252019220250.310 Why?
Nerve Tissue Proteins5200244090.300 Why?
CCAAT-Enhancer-Binding Protein-alpha220061300.300 Why?
Antigens, CD10200340020.300 Why?
Homeostasis12200833050.290 Why?
Proteasome Endopeptidase Complex1201313140.270 Why?
Mice, Knockout192015143960.270 Why?
Fatty Acids6200618050.270 Why?
Adipogenesis220063580.260 Why?
Intercellular Signaling Peptides and Proteins5200516550.260 Why?
Transcription Factors72008121000.260 Why?
Signal Transduction182017233630.260 Why?
Mammary Glands, Human120072040.250 Why?
Mammary Glands, Animal120072650.250 Why?
Cholesterol5200729250.250 Why?
PPAR gamma220054840.250 Why?
Hormones120088670.240 Why?
Lipolysis320002110.240 Why?
Mitogen-Activated Protein Kinases3200412460.230 Why?
DNA-Binding Proteins5200595900.230 Why?
Gene Expression Regulation122012119020.230 Why?
Apoptosis6201294970.230 Why?
Cell Lineage3201525250.230 Why?
Triglycerides8201324760.230 Why?
Glucose Tolerance Test6200611740.230 Why?
Tumor Suppressor Proteins4200828040.220 Why?
Hypothalamus120089980.220 Why?
Blood Glucose8200863750.210 Why?
Receptors, Cytoplasmic and Nuclear320058540.210 Why?
Food220077720.210 Why?
Insulin Receptor Substrate Proteins620085570.210 Why?
Metabolic Networks and Pathways120077880.210 Why?
Hypertriglyceridemia120063160.210 Why?
Gene Expression6200675920.200 Why?
Apolipoproteins E5200714370.200 Why?
Mice, Transgenic11200995310.190 Why?
Receptors, Tumor Necrosis Factor, Type II820063460.190 Why?
eIF-2 Kinase320081440.190 Why?
Cytokines4201773450.190 Why?
Cell Line112008156260.190 Why?
Protein Folding320108670.180 Why?
Fatty Liver120067770.180 Why?
Organ Specificity3201719550.170 Why?
Phosphorylation9200683140.170 Why?
Membrane Proteins4200778540.170 Why?
Blotting, Northern5200515440.170 Why?
Lipids8201333360.170 Why?
RNA, Messenger152009127620.170 Why?
Glycogen120192510.160 Why?
Mice, Mutant Strains4200717600.150 Why?
Interleukin-67200732070.140 Why?
Phosphoproteins5200424410.140 Why?
Neovascularization, Physiologic2201513350.140 Why?
Stearoyl-CoA Desaturase22008850.140 Why?
Humans6120197602610.140 Why?
Cells, Cultured92012189680.140 Why?
Cell Communication2201716420.130 Why?
Biological Evolution2201710740.130 Why?
3T3 Cells6200610850.130 Why?
Adenylate Kinase220061020.130 Why?
Body Composition2200324180.130 Why?
Body Weight6200646130.130 Why?
Promoter Regions, Genetic5200657840.130 Why?
Receptors, Adrenergic, beta320012410.130 Why?
I-kappa B Kinase220082510.130 Why?
Polymorphism, Genetic1200642860.130 Why?
Hypercholesterolemia1200211550.130 Why?
Mast Cells2201514280.130 Why?
Plasminogen Activator Inhibitor 1320032800.120 Why?
Ethylene Glycols119961900.120 Why?
Cryoprotective Agents119961290.120 Why?
Epithelial Cells1200736650.120 Why?
Cell Membrane3200236830.120 Why?
Organ Size3200422490.120 Why?
Reverse Transcriptase Polymerase Chain Reaction4200645730.120 Why?
Models, Biological5200894680.110 Why?
Adaptive Immunity120177240.100 Why?
Weight Gain2201923470.100 Why?
Muscle Proteins1199711520.100 Why?
Immune System120177950.100 Why?
Stem Cell Factor120121980.100 Why?
Bone Marrow Transplantation3200826960.100 Why?
Resistin220031720.090 Why?
Oocytes1199611650.090 Why?
Cytoskeleton1199611670.090 Why?
Cryopreservation119967200.090 Why?
Nerve Growth Factor220031580.090 Why?
Male3920193594130.090 Why?
Thinness320064910.090 Why?
Aorta4201520420.090 Why?
Inflammation Mediators2201718820.090 Why?
Immunoblotting2200516490.090 Why?
Dietary Fats3201319920.090 Why?
Receptors, Adrenergic, beta-322000620.090 Why?
Muscle, Skeletal5200849230.090 Why?
Blotting, Western6201250390.090 Why?
Multiprotein Complexes2200811200.090 Why?
Protein Isoforms2200616970.090 Why?
Chemokine CXCL512009280.080 Why?
Retinopathy of Prematurity120144320.080 Why?
Dairy Products120134940.080 Why?
Genes, Reporter2200515310.080 Why?
Cromolyn Sodium12009770.080 Why?
Rats52005236950.080 Why?
HIV-11200668500.080 Why?
Diet7201380080.080 Why?
Transcription, Genetic5200675930.070 Why?
Hyperinsulinism320083980.070 Why?
Ligands2200832770.070 Why?
Body Fat Distribution120082430.070 Why?
Mutation82007299500.070 Why?
Lipogenesis120082100.070 Why?
3T3-L1 Cells120072090.070 Why?
C-Reactive Protein4200738220.070 Why?
Hepatocyte Nuclear Factor 3-alpha120071650.070 Why?
Female2620193910110.060 Why?
Chemokine CCL2120086070.060 Why?
Receptors, HIV120061590.060 Why?
Multiple Birth Offspring12005220.060 Why?
Eukaryotic Initiation Factor-2120061800.060 Why?
Proto-Oncogene Proteins c-kit120097290.060 Why?
Immunity, Innate1201730460.060 Why?
HIV-Associated Lipodystrophy Syndrome120061380.060 Why?
Orphan Nuclear Receptors12005630.060 Why?
Tunicamycin120041080.060 Why?
CCAAT-Enhancer-Binding Protein-beta120051020.060 Why?
NF-kappa B2200524860.060 Why?
Recombinant Fusion Proteins2200537350.060 Why?
Protein Tyrosine Phosphatases120064590.060 Why?
Mitochondrial Proteins220009790.060 Why?
Prostaglandin-Endoperoxide Synthases120053180.060 Why?
Body Mass Index92005129010.060 Why?
Mesentery120042030.060 Why?
Luciferases120057160.060 Why?
Reference Values4200349200.060 Why?
Genes, Tumor Suppressor1200810560.060 Why?
Tissue Distribution2200522620.050 Why?
Nitric Oxide Synthase Type II120055140.050 Why?
Protein Binding2200693360.050 Why?
CD40 Ligand120055220.050 Why?
Diabetes Mellitus, Experimental1200911090.050 Why?
Mice, Congenic12002970.050 Why?
Cardiovascular Diseases22006157400.050 Why?
Immunosorbent Techniques120021760.050 Why?
Cyclooxygenase 2120056000.050 Why?
Phenotype32006165430.050 Why?
Biphenyl Compounds120079880.050 Why?
Endothelium, Vascular2201244370.050 Why?
Enzyme Activation2200636040.050 Why?
CHO Cells1200513890.050 Why?
Microscopy, Electron1200525580.050 Why?
Tyrosine3200114400.050 Why?
Base Sequence22006124470.050 Why?
Diet, Fat-Restricted120043300.050 Why?
Nitric Oxide Synthase120059080.050 Why?
Premenopause2199710390.050 Why?
Crosses, Genetic120037510.050 Why?
Blood Specimen Collection120032380.050 Why?
Encephalomyelitis, Autoimmune, Experimental120078250.050 Why?
Isoenzymes1200616900.050 Why?
Gene Expression Regulation, Enzymologic1200611730.050 Why?
Blotting, Southern120027780.050 Why?
Multienzyme Complexes120056660.050 Why?
Disease Models, Animal42006181340.050 Why?
AMP-Activated Protein Kinases120056000.050 Why?
T-Lymphocytes, Helper-Inducer120079750.050 Why?
Precipitin Tests120028150.050 Why?
Benzophenones12001580.050 Why?
Indicators and Reagents120024610.050 Why?
Cricetinae1200524270.050 Why?
Myeloid Cells120068210.050 Why?
Chemotaxis220155980.050 Why?
Protein Biosynthesis2199921040.050 Why?
Cell Adhesion Molecules1200716020.050 Why?
Uncoupling Agents12000460.050 Why?
Haptoglobins120021670.050 Why?
Sirolimus1200815480.050 Why?
ADAM Proteins120022400.050 Why?
Reproductive Techniques, Assisted120054980.040 Why?
Metalloendopeptidases120023940.040 Why?
HIV Infections22006171590.040 Why?
Hepatocytes1200712280.040 Why?
Biological Transport1200520870.040 Why?
Nutritional Status1200816060.040 Why?
Gastric Bypass120088260.040 Why?
Fatty Acids, Unsaturated120035420.040 Why?
Genetic Markers1200626080.040 Why?
Hypoglycemic Agents2200431490.040 Why?
Proto-Oncogene Proteins c-akt1200824490.040 Why?
Hyperlipoproteinemia Type II120043960.040 Why?
Binding Sites1200860500.040 Why?
Eating2200615380.040 Why?
Cell Line, Tumor22006169050.040 Why?
Drug Interactions1200414260.040 Why?
In Situ Nick-End Labeling120006130.040 Why?
Leukocytes, Mononuclear1200618280.040 Why?
Interleukin-21200618900.040 Why?
Lymphocyte Activation2200754980.040 Why?
TOR Serine-Threonine Kinases1200820580.040 Why?
Oxygen2201441890.040 Why?
Dendritic Cells2200727300.040 Why?
Ion Channels2200010430.040 Why?
Social Behavior1200511300.040 Why?
Lipoproteins, HDL120036670.040 Why?
Vascular Diseases1200711800.040 Why?
Zinc Fingers120005680.040 Why?
Life Style4200538880.040 Why?
Mutagenesis, Site-Directed1200116940.040 Why?
Up-Regulation3200241270.040 Why?
Asthma2200761670.040 Why?
Models, Molecular1200854290.040 Why?
Neurons2200894160.040 Why?
Antiretroviral Therapy, Highly Active1200618940.040 Why?
Adaptor Proteins, Signal Transducing1200828950.040 Why?
Cloning, Molecular1200341720.040 Why?
Glucose Transporter Type 4119972400.040 Why?
Time Factors52006401330.040 Why?
Blood Pressure1201385230.040 Why?
Hypersensitivity1200611590.040 Why?
Body Temperature120007770.040 Why?
Absorptiometry, Photon1200317310.030 Why?
Longevity1200410500.030 Why?
Oxidative Stress1200831070.030 Why?
Actins3200220490.030 Why?
Pyrazoles1200719920.030 Why?
Molecular Sequence Data22007176280.030 Why?
Odds Ratio2200697120.030 Why?
Ethylene Glycol11996310.030 Why?
Cold Temperature120007800.030 Why?
Regression Analysis2199763610.030 Why?
Cyclic AMP1200014550.030 Why?
Kinetics1200463780.030 Why?
Rats, Zucker119961320.030 Why?
Sphingomyelin Phosphodiesterase11996820.030 Why?
Structure-Activity Relationship1200130860.030 Why?
Middle Aged1720132201750.030 Why?
PPAR delta12015400.030 Why?
Monosaccharide Transport Proteins119974400.030 Why?
Prospective Studies82013542630.030 Why?
Mice, Inbred BALB C1200462260.030 Why?
Exercise2200357830.030 Why?
Feces1200214660.030 Why?
Cytoprotection120152000.030 Why?
DNA Primers1199928190.030 Why?
Gene Deletion1200226680.030 Why?
Models, Genetic1200534420.030 Why?
Protein Structure, Tertiary1200138000.030 Why?
Myocardial Ischemia1200521610.030 Why?
Membrane Transport Proteins1200010360.030 Why?
Islets of Langerhans1200013410.030 Why?
Adult1420062198470.030 Why?
Interleukin-12220065840.030 Why?
Cell Survival2201557960.030 Why?
Down-Regulation1200129180.030 Why?
Thiazoles1200115090.030 Why?
Fatty Acids, Omega-31200313870.030 Why?
Pancreas1200016770.030 Why?
Hydrogenation12013200.030 Why?
Adaptation, Physiological1200012970.030 Why?
CD4-Positive T-Lymphocytes1200643550.030 Why?
Gene Targeting119968390.030 Why?
Cohort Studies52007413170.030 Why?
Disease Progression22007135050.030 Why?
T-Lymphocytes22007101830.030 Why?
Serine119968310.020 Why?
Trans Fatty Acids120131550.020 Why?
Genotype12006129590.020 Why?
Weight Loss1200226830.020 Why?
Feeding Behavior1200331850.020 Why?
DNA1200572360.020 Why?
Repressor Proteins1200129780.020 Why?
Cell Death1201516700.020 Why?
C-Peptide220034330.020 Why?
Interleukin-12200612500.020 Why?
Sex Characteristics1200026270.020 Why?
Nuclear Proteins1200457930.020 Why?
Diet, Atherogenic12009930.020 Why?
Receptors, Leptin220013500.020 Why?
Radioimmunoassay220018660.020 Why?
Case-Control Studies52007220410.020 Why?
Phospholipids120137890.020 Why?
Microscopy, Fluorescence1199626510.020 Why?
Glucose Clamp Technique120082630.020 Why?
Retinal Vessels120148360.020 Why?
Fluorescent Dyes1199619140.020 Why?
Recombinant Proteins1199765430.020 Why?
Anthropometry2200413480.020 Why?
Stem Cells1200035250.020 Why?
Thrombosis1200130520.020 Why?
Lymphocyte Culture Test, Mixed120065140.020 Why?
Protein Tyrosine Phosphatase, Non-Receptor Type 112006950.020 Why?
I-kappa B Proteins120062120.020 Why?
Injections, Intraperitoneal120064130.020 Why?
Child, Preschool12008420340.020 Why?
Phosphoprotein Phosphatases120063300.020 Why?
Antineoplastic Agents12008136290.020 Why?
E-Selectin120075760.020 Why?
Aging2200186410.010 Why?
Cross-Sectional Studies52005259280.010 Why?
Vascular Cell Adhesion Molecule-1120076940.010 Why?
Genetic Predisposition to Disease12006177660.010 Why?
Drug Evaluation, Preclinical1200913460.010 Why?
Risk Factors62013742690.010 Why?
Follow-Up Studies42008392540.010 Why?
Neovascularization, Pathologic1201426410.010 Why?
Immunoprecipitation120068770.010 Why?
Adoptive Transfer120068250.010 Why?
Quality of Life12005133000.010 Why?
RNA Interference1201228460.010 Why?
Cholesterol, LDL1201324220.010 Why?
Intercellular Adhesion Molecule-11200711280.010 Why?
Psychology120053550.010 Why?
Respiratory Mucosa120064410.010 Why?
Aged820131689950.010 Why?
Myocardial Infarction12004118910.010 Why?
Interleukin-41200611330.010 Why?
Bronchi120068480.010 Why?
Clenbuterol1200190.010 Why?
Organic Anion Transporters120021000.010 Why?
Fatty Acids, Omega-6120032270.010 Why?
Antigen Presentation1200712540.010 Why?
Dobutamine120011160.010 Why?
Dioxoles12001950.010 Why?
Isoproterenol120013940.010 Why?
Cholesterol Esters12001730.010 Why?
Eicosanoids120032780.010 Why?
Foam Cells12001680.010 Why?
Protein Kinase C1200612010.010 Why?
Th2 Cells1200610480.010 Why?
Adrenergic alpha-Agonists120011780.010 Why?
Suppressor of Cytokine Signaling Proteins120011730.010 Why?
Oxidation-Reduction1200622220.010 Why?
Adrenergic beta-Agonists120013450.010 Why?
Embryo, Mammalian1200616670.010 Why?
Food Deprivation120001140.010 Why?
Cell Proliferation12015104340.010 Why?
COS Cells1200111290.010 Why?
Solubility1200110880.010 Why?
Glycoproteins1200722080.010 Why?
Multivariate Analysis22005121560.010 Why?
Hyperphagia120001380.010 Why?
Confidence Intervals1200529320.010 Why?
Breast Neoplasms12007210650.010 Why?
Endothelial Cells1201235370.010 Why?
Menopause1200716400.010 Why?
Bone Marrow Cells1200624240.010 Why?
Norepinephrine120019000.010 Why?
Spinal Cord1200718170.010 Why?
Neoplasms12008220660.010 Why?
Cell Culture Techniques1200616630.010 Why?
Drug Administration Schedule1200649000.010 Why?
Postmenopause1200725030.010 Why?
Energy Intake1200321280.010 Why?
Amino Acid Sequence12007134560.010 Why?
Fibroblasts1200640910.010 Why?
Ceramides119962000.010 Why?
Risk1200796290.010 Why?
Peptide Fragments1200751200.010 Why?
United States32013723630.010 Why?
Temperature1199922210.010 Why?
Membrane Glycoproteins1200237310.010 Why?
Transforming Growth Factor beta1199919560.010 Why?
Socioeconomic Factors1200578030.010 Why?
Biopsy1200167750.010 Why?
Health Personnel1200333100.010 Why?
Sex Factors12003105300.010 Why?
Predictive Value of Tests12005152730.000 Why?
Smoking1200190700.000 Why?
Brain12007269120.000 Why?
Aged, 80 and over12001589470.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.