Lymphocyte Culture Test, Mixed
"Lymphocyte Culture Test, Mixed" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Measure of histocompatibility at the HL-A locus. Peripheral blood lymphocytes from two individuals are mixed together in tissue culture for several days. Lymphocytes from incompatible individuals will stimulate each other to proliferate significantly (measured by tritiated thymidine uptake) whereas those from compatible individuals will not. In the one-way MLC test, the lymphocytes from one of the individuals are inactivated (usually by treatment with MITOMYCIN or radiation) thereby allowing only the untreated remaining population of cells to proliferate in response to foreign histocompatibility antigens.
MeSH Number(s)
E01.370.225.812.385.475
E05.200.812.385.475
E05.478.594.385.429
Concept/Terms
Lymphocyte Culture Test, Mixed- Lymphocyte Culture Test, Mixed
- Mixed Lymphocyte Reaction
- Lymphocyte Reaction, Mixed
- Lymphocyte Reactions, Mixed
- Mixed Lymphocyte Reactions
- Mixed Lymphocyte Culture Test
- Mixed Leukocyte Reaction
- Leukocyte Reaction, Mixed
- Leukocyte Reactions, Mixed
- Mixed Leukocyte Reactions
- Mixed Leukocyte Culture Test
- Leukocyte Culture Test, Mixed
Below are MeSH descriptors whose meaning is more general than "Lymphocyte Culture Test, Mixed".
Below are MeSH descriptors whose meaning is more specific than "Lymphocyte Culture Test, Mixed".
This graph shows the total number of publications written about "Lymphocyte Culture Test, Mixed" by people in Harvard Catalyst Profiles by year, and whether "Lymphocyte Culture Test, Mixed" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 4 | 4 |
| 1995 | 2 | 10 | 12 |
| 1996 | 1 | 15 | 16 |
| 1997 | 0 | 12 | 12 |
| 1998 | 0 | 2 | 2 |
| 1999 | 0 | 13 | 13 |
| 2000 | 0 | 7 | 7 |
| 2001 | 0 | 12 | 12 |
| 2002 | 0 | 11 | 11 |
| 2003 | 0 | 9 | 9 |
| 2004 | 0 | 4 | 4 |
| 2005 | 0 | 5 | 5 |
| 2006 | 0 | 5 | 5 |
| 2007 | 0 | 12 | 12 |
| 2008 | 1 | 6 | 7 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 4 | 4 |
| 2012 | 0 | 5 | 5 |
| 2013 | 0 | 5 | 5 |
| 2014 | 0 | 5 | 5 |
| 2015 | 0 | 5 | 5 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 3 | 3 |
| 2019 | 1 | 1 | 2 |
| 2020 | 1 | 1 | 2 |
| 2021 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
Below are the most recent publications written about "Lymphocyte Culture Test, Mixed" by people in Profiles.
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Identification and Tracking of Alloreactive T Cell Clones in Rhesus Macaques Through the RM-scTCR-Seq Platform. Front Immunol. 2021; 12:804932.
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Detection of alloreactive T cells from cryopreserved human peripheral blood mononuclear cells. J Immunol Methods. 2021 04; 491:112987.
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The human T-cell proliferative response to triple-knockout pig cells in mixed lymphocyte reaction. Xenotransplantation. 2020 09; 27(5):e12619.
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Toward Development of the Delayed Tolerance Induction Protocol for Vascularized Composite Allografts in Nonhuman Primates. Plast Reconstr Surg. 2020 04; 145(4):757e-768e.
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Siplizumab selectively depletes effector memory T cells and promotes a relative expansion of alloreactive regulatory T cells in vitro. Am J Transplant. 2020 01; 20(1):88-100.
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Dendritic cells mediate the anti-inflammatory action of omega-3 long-chain polyunsaturated fatty acids in experimental autoimmune uveitis. PLoS One. 2019; 14(7):e0219405.
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Alloanergization Method for Inducing Allospecific Hyporesponsiveness in PBMC Exposed to Allostimulation In Vitro in the Context of Costimulatory Molecule Blockade. Methods Mol Biol. 2019; 1899:103-118.
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Mesenchymal stromal cells from infants with simple polydactyly modulate immune responses more efficiently than adult mesenchymal stromal cells. Cytotherapy. 2019 02; 21(2):148-161.
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Early expansion of donor-specific Tregs in tolerant kidney transplant recipients. JCI Insight. 2018 11 15; 3(22).
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In vitro MSC function is related to clinical reaction in vivo. Stem Cell Res Ther. 2018 11 08; 9(1):295.