"Cyclooxygenase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inducibly-expressed subtype of prostaglandin-endoperoxide synthase. It plays an important role in many cellular processes and INFLAMMATION. It is the target of COX2 INHIBITORS.
Concept/Terms
Cyclooxygenase 2- Cyclooxygenase 2
- Cyclo-Oxygenase II
- Cyclo Oxygenase II
- PTGS2
- PGHS-2
- Prostaglandin H Synthase-2
- Prostaglandin H Synthase 2
- COX-2 Prostaglandin Synthase
- COX 2 Prostaglandin Synthase
- Prostaglandin Synthase, COX-2
- Synthase, COX-2 Prostaglandin
- Cyclooxygenase-2
Below are MeSH descriptors whose meaning is more general than "Cyclooxygenase 2".
Below are MeSH descriptors whose meaning is more specific than "Cyclooxygenase 2".
This graph shows the total number of publications written about "Cyclooxygenase 2" by people in Harvard Catalyst Profiles by year, and whether "Cyclooxygenase 2" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 5 | 5 |
1997 | 0 | 4 | 4 |
1998 | 0 | 7 | 7 |
1999 | 0 | 16 | 16 |
2000 | 0 | 14 | 14 |
2001 | 0 | 14 | 14 |
2002 | 0 | 20 | 20 |
2003 | 0 | 32 | 32 |
2004 | 0 | 35 | 35 |
2005 | 6 | 22 | 28 |
2006 | 11 | 11 | 22 |
2007 | 11 | 6 | 17 |
2008 | 11 | 2 | 13 |
2009 | 15 | 6 | 21 |
2010 | 6 | 12 | 18 |
2011 | 7 | 8 | 15 |
2012 | 3 | 12 | 15 |
2013 | 3 | 12 | 15 |
2014 | 4 | 8 | 12 |
2015 | 5 | 14 | 19 |
2016 | 5 | 4 | 9 |
2017 | 6 | 7 | 13 |
2018 | 5 | 7 | 12 |
2019 | 5 | 7 | 12 |
2020 | 3 | 3 | 6 |
2021 | 2 | 3 | 5 |
2022 | 0 | 3 | 3 |
2023 | 0 | 4 | 4 |
Below are the most recent publications written about "Cyclooxygenase 2" by people in Profiles.
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Blockade of EP4 by ASP7657 Modulates Myeloid Cell Differentiation In Vivo and Enhances the Antitumor Effect of Radiotherapy. Biomed Res Int. 2023; 2023:7133726.
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The caecal microbiota promotes the acute inflammatory response and the loss of the intestinal barrier integrity during severe Eimeria tenella infection. Front Cell Infect Microbiol. 2023; 13:1250080.
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Alterations of pain pathways by experimental sleep disturbances in humans: central pain-inhibitory, cyclooxygenase, and endocannabinoid pathways. Sleep. 2023 06 13; 46(6).
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Regulation of inflammation in cancer by dietary eicosanoids. Pharmacol Ther. 2023 08; 248:108455.
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Follicular fluid progesterone downregulated HPGD and COX2 in granulosa cells via suppressing NF-?B in endometriosis†. Biol Reprod. 2023 05 10; 108(5):791-801.
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Phytochemical Combination Is More Effective than Individual Components in Reducing Stress Signaling in Rat Hippocampal Neurons and Microglia In Vitro. Int J Mol Sci. 2022 Oct 21; 23(20).
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Resolvin E1 Reduces Tumor Growth in a Xenograft Model of Lung Cancer. Am J Pathol. 2022 Oct; 192(10):1470-1484.
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Prophylactic (R,S)-Ketamine Is Effective Against Stress-Induced Behaviors in Adolescent but Not Aged Mice. Int J Neuropsychopharmacol. 2022 06 21; 25(6):512-523.
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Staphylococcus aureus controls eicosanoid and specialized pro-resolving mediator production via lipoteichoic acid. Immunology. 2022 05; 166(1):47-67.
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The Fusion Protein rFlaA:Betv1 Modulates DC Responses by a p38-MAPK and COX2-Dependent Secretion of PGE2 from Epithelial Cells. Cells. 2021 12 04; 10(12).