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Sphingomyelin Phosphodiesterase

"Sphingomyelin Phosphodiesterase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

An enzyme that catalyzes the hydrolysis of sphingomyelin to ceramide (N-acylsphingosine) plus choline phosphate. A defect in this enzyme leads to NIEMANN-PICK DISEASE. EC 3.1.4.12.


This graph shows the total number of publications written about "Sphingomyelin Phosphodiesterase" by people in Harvard Catalyst Profiles by year, and whether "Sphingomyelin Phosphodiesterase" was a major or minor topic of these publication.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.