"Receptors, Leptin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is mediated through the JAK2/STAT3 pathway to regulate food intake, energy balance and fat storage.
Concept/Terms
Receptors, Leptin- Receptors, Leptin
- CD295 Antigens
- LEPR Protein
- Leptin Receptor
- Leptin-Binding Protein
- Leptin Binding Protein
- OB Receptor
- Receptor, OB
- Receptor, Leptin
- Antigens, CD295
- Leptin Receptors
OBRb Receptor- OBRb Receptor
- Receptor, OBRb
- Leptin Receptor, Large Isoform
Below are MeSH descriptors whose meaning is more general than "Receptors, Leptin".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Leptin".
This graph shows the total number of publications written about "Receptors, Leptin" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Leptin" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 1996 | 0 | 6 | 6 |
| 1997 | 0 | 6 | 6 |
| 1998 | 0 | 6 | 6 |
| 1999 | 0 | 5 | 5 |
| 2000 | 0 | 12 | 12 |
| 2001 | 0 | 6 | 6 |
| 2002 | 0 | 6 | 6 |
| 2003 | 0 | 10 | 10 |
| 2004 | 0 | 12 | 12 |
| 2005 | 0 | 9 | 9 |
| 2006 | 0 | 11 | 11 |
| 2007 | 2 | 5 | 7 |
| 2008 | 2 | 2 | 4 |
| 2009 | 4 | 7 | 11 |
| 2010 | 4 | 6 | 10 |
| 2011 | 6 | 5 | 11 |
| 2012 | 5 | 2 | 7 |
| 2013 | 6 | 3 | 9 |
| 2014 | 3 | 6 | 9 |
| 2015 | 0 | 9 | 9 |
| 2016 | 2 | 3 | 5 |
| 2017 | 3 | 5 | 8 |
| 2018 | 5 | 7 | 12 |
| 2019 | 1 | 7 | 8 |
| 2020 | 4 | 2 | 6 |
| 2021 | 1 | 1 | 2 |
| 2022 | 1 | 1 | 2 |
| 2023 | 1 | 1 | 2 |
| 2024 | 0 | 1 | 1 |
Below are the most recent publications written about "Receptors, Leptin" by people in Profiles.
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Central inhibition of HDAC6 re-sensitizes leptin signaling during obesity to induce profound weight loss. Cell Metab. 2024 Apr 02; 36(4):857-876.e10.
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Leptin receptor+ cells promote bone marrow innervation and regeneration by synthesizing nerve growth factor. Nat Cell Biol. 2023 Dec; 25(12):1746-1757.
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Sex-Specific Associations between Adiponectin and Leptin Signaling and Pancreatic Cancer Survival. Cancer Epidemiol Biomarkers Prev. 2023 10 02; 32(10):1458-1469.
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Exercise training worsens cardiac performance in males but does not change ejection fraction and improves hypertrophy in females in a mouse model of metabolic syndrome. Biol Sex Differ. 2022 01 31; 13(1):5.
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Characterization of Leptin Receptor+ Stromal Cells in Lymph Node. Front Immunol. 2021; 12:730438.
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The Origin and Contribution of Cancer-Associated Fibroblasts in Colorectal Carcinogenesis. Gastroenterology. 2022 03; 162(3):890-906.
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Leptin brain entry via a tanycytic LepR-EGFR shuttle controls lipid metabolism and pancreas function. Nat Metab. 2021 08; 3(8):1071-1090.
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A mechanosensitive peri-arteriolar niche for osteogenesis and lymphopoiesis. Nature. 2021 03; 591(7850):438-444.
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LRP1 regulates food intake and energy balance in GABAergic neurons independently of leptin action. Am J Physiol Endocrinol Metab. 2021 02 01; 320(2):E379-E389.
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Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials. Lancet Diabetes Endocrinol. 2020 12; 8(12):960-970.