Penelope Jane Hallett, Ph.D.
Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
| Name | Number of Publications
|
Most Recent Publication
|
Publications by All Authors
|
Concept Score
|
Why?
|
|---|
| Parkinson Disease | 26 | 2023 | 2859 | 2.310 |
Why?
|
| Glucosylceramidase | 11 | 2023 | 125 | 1.820 |
Why?
|
| alpha-Synuclein | 12 | 2023 | 749 | 1.730 |
Why?
|
| Substantia Nigra | 7 | 2020 | 350 | 1.060 |
Why?
|
| Mesencephalon | 4 | 2017 | 332 | 1.040 |
Why?
|
| Lysosomes | 9 | 2023 | 920 | 1.020 |
Why?
|
| Lewy Body Disease | 1 | 2023 | 252 | 0.740 |
Why?
|
| beta-N-Acetylhexosaminidases | 1 | 2020 | 43 | 0.730 |
Why?
|
| Gangliosides | 1 | 2020 | 131 | 0.680 |
Why?
|
| Corpus Striatum | 8 | 2011 | 1233 | 0.660 |
Why?
|
| Nerve Degeneration | 5 | 2019 | 748 | 0.650 |
Why?
|
| Secretogranin II | 1 | 2018 | 9 | 0.650 |
Why?
|
| Glycosphingolipids | 2 | 2021 | 73 | 0.640 |
Why?
|
| Receptors, N-Methyl-D-Aspartate | 5 | 2009 | 893 | 0.580 |
Why?
|
| Dyskinesias | 2 | 2007 | 79 | 0.500 |
Why?
|
| Axonal Transport | 2 | 2015 | 178 | 0.470 |
Why?
|
| Induced Pluripotent Stem Cells | 5 | 2023 | 1846 | 0.470 |
Why?
|
| Toll-Like Receptor 3 | 3 | 2023 | 98 | 0.420 |
Why?
|
| Fetal Tissue Transplantation | 3 | 2009 | 137 | 0.420 |
Why?
|
| Receptors, Dopamine D1 | 4 | 2009 | 293 | 0.390 |
Why?
|
| Stem Cell Transplantation | 3 | 2015 | 1599 | 0.380 |
Why?
|
| tau Proteins | 2 | 2019 | 2085 | 0.380 |
Why?
|
| Lipids | 2 | 2020 | 3336 | 0.370 |
Why?
|
| Neurons | 11 | 2019 | 9426 | 0.360 |
Why?
|
| Dopamine | 7 | 2018 | 1595 | 0.350 |
Why?
|
| Brain | 9 | 2023 | 26951 | 0.350 |
Why?
|
| Oxidative Stress | 2 | 2018 | 3106 | 0.340 |
Why?
|
| Huntington Disease | 2 | 2014 | 1141 | 0.330 |
Why?
|
| Autonomic Nervous System Diseases | 1 | 2012 | 269 | 0.330 |
Why?
|
| Sequence Analysis, RNA | 1 | 2017 | 2005 | 0.320 |
Why?
|
| Synapses | 3 | 2014 | 1757 | 0.320 |
Why?
|
| Membrane Glycoproteins | 2 | 2020 | 3707 | 0.310 |
Why?
|
| Dyskinesia, Drug-Induced | 4 | 2010 | 165 | 0.310 |
Why?
|
| Parkinsonian Disorders | 5 | 2013 | 284 | 0.310 |
Why?
|
| Cell Fractionation | 1 | 2008 | 251 | 0.290 |
Why?
|
| Protein Transport | 4 | 2021 | 1964 | 0.280 |
Why?
|
| Receptors, Opioid, delta | 1 | 2007 | 48 | 0.280 |
Why?
|
| Behavior, Animal | 2 | 2014 | 1866 | 0.270 |
Why?
|
| Levodopa | 5 | 2010 | 217 | 0.270 |
Why?
|
| Aging | 5 | 2021 | 8651 | 0.260 |
Why?
|
| Gastrointestinal Tract | 1 | 2012 | 830 | 0.260 |
Why?
|
| Urinary Bladder | 1 | 2012 | 1166 | 0.260 |
Why?
|
| MPTP Poisoning | 1 | 2005 | 37 | 0.250 |
Why?
|
| Animals | 35 | 2023 | 167963 | 0.240 |
Why?
|
| Mice, Inbred DBA | 2 | 2018 | 622 | 0.230 |
Why?
|
| Protein Tyrosine Phosphatases | 1 | 2006 | 459 | 0.230 |
Why?
|
| RNA, Double-Stranded | 2 | 2023 | 295 | 0.230 |
Why?
|
| Dopamine Plasma Membrane Transport Proteins | 3 | 2014 | 415 | 0.230 |
Why?
|
| Glycolipids | 2 | 2023 | 204 | 0.220 |
Why?
|
| Pluripotent Stem Cells | 3 | 2017 | 792 | 0.210 |
Why?
|
| Gaucher Disease | 1 | 2023 | 110 | 0.210 |
Why?
|
| Neurotransmitter Agents | 2 | 2018 | 663 | 0.210 |
Why?
|
| Inflammation | 2 | 2019 | 10756 | 0.200 |
Why?
|
| Tyrosine | 1 | 2006 | 1438 | 0.190 |
Why?
|
| Rats | 13 | 2020 | 23711 | 0.190 |
Why?
|
| Complement C3 | 1 | 2023 | 451 | 0.190 |
Why?
|
| Rats, Sprague-Dawley | 9 | 2020 | 8158 | 0.190 |
Why?
|
| Lysosomal Storage Diseases | 1 | 2021 | 79 | 0.190 |
Why?
|
| Sandhoff Disease | 1 | 2020 | 14 | 0.180 |
Why?
|
| Neostriatum | 2 | 2014 | 246 | 0.180 |
Why?
|
| Receptors, Scavenger | 1 | 2021 | 123 | 0.180 |
Why?
|
| Disease Models, Animal | 11 | 2020 | 18137 | 0.170 |
Why?
|
| Fibroblasts | 3 | 2021 | 4090 | 0.170 |
Why?
|
| Macaca fascicularis | 4 | 2015 | 900 | 0.170 |
Why?
|
| Mice, Inbred C57BL | 6 | 2020 | 22023 | 0.160 |
Why?
|
| Mice | 15 | 2023 | 81208 | 0.160 |
Why?
|
| Receptors, Cell Surface | 1 | 2008 | 2825 | 0.150 |
Why?
|
| Glucosylceramides | 1 | 2018 | 28 | 0.150 |
Why?
|
| Brain Tissue Transplantation | 2 | 2008 | 81 | 0.150 |
Why?
|
| Lysosomal-Associated Membrane Protein 2 | 1 | 2018 | 52 | 0.150 |
Why?
|
| Parkinson Disease, Secondary | 2 | 2015 | 122 | 0.150 |
Why?
|
| Polyubiquitin | 1 | 2018 | 68 | 0.150 |
Why?
|
| Syndrome | 1 | 2023 | 3280 | 0.140 |
Why?
|
| Neurites | 1 | 2018 | 390 | 0.140 |
Why?
|
| Mitochondrial Diseases | 1 | 2020 | 340 | 0.140 |
Why?
|
| 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine | 4 | 2010 | 90 | 0.130 |
Why?
|
| Gene Expression Regulation | 3 | 2019 | 11903 | 0.130 |
Why?
|
| Mice, Transgenic | 4 | 2018 | 9530 | 0.130 |
Why?
|
| Inclusion Bodies | 2 | 2014 | 281 | 0.130 |
Why?
|
| Nuclear Receptor Subfamily 4, Group A, Member 2 | 1 | 2015 | 42 | 0.130 |
Why?
|
| Complement C1q | 1 | 2015 | 94 | 0.120 |
Why?
|
| Poly I-C | 2 | 2015 | 112 | 0.120 |
Why?
|
| Inositol | 1 | 2015 | 215 | 0.120 |
Why?
|
| Synapsins | 1 | 2014 | 43 | 0.120 |
Why?
|
| Antiparkinson Agents | 3 | 2010 | 183 | 0.120 |
Why?
|
| Calcium Signaling | 1 | 2018 | 732 | 0.120 |
Why?
|
| Receptor, trkB | 1 | 2014 | 125 | 0.110 |
Why?
|
| Macaca mulatta | 4 | 2010 | 2316 | 0.110 |
Why?
|
| Microglia | 3 | 2020 | 1351 | 0.110 |
Why?
|
| Gene Knock-In Techniques | 1 | 2014 | 419 | 0.100 |
Why?
|
| Triglycerides | 1 | 2020 | 2476 | 0.100 |
Why?
|
| Endosomal Sorting Complexes Required for Transport | 1 | 2013 | 150 | 0.100 |
Why?
|
| Serotonin Plasma Membrane Transport Proteins | 1 | 2014 | 324 | 0.100 |
Why?
|
| Up-Regulation | 1 | 2020 | 4122 | 0.090 |
Why?
|
| Green Fluorescent Proteins | 2 | 2014 | 2057 | 0.090 |
Why?
|
| Transgenes | 1 | 2014 | 1006 | 0.090 |
Why?
|
| Radioligand Assay | 2 | 2009 | 366 | 0.090 |
Why?
|
| Brain-Derived Neurotrophic Factor | 1 | 2014 | 599 | 0.090 |
Why?
|
| rab3 GTP-Binding Proteins | 1 | 2009 | 29 | 0.090 |
Why?
|
| Adenoviridae | 1 | 2014 | 1084 | 0.090 |
Why?
|
| Humans | 32 | 2023 | 760621 | 0.080 |
Why?
|
| Protein Isoforms | 1 | 2014 | 1697 | 0.080 |
Why?
|
| Mutation | 6 | 2023 | 29932 | 0.080 |
Why?
|
| Cytoskeleton | 1 | 2014 | 1167 | 0.080 |
Why?
|
| Mice, Inbred BALB C | 1 | 2018 | 6216 | 0.080 |
Why?
|
| Atrophy | 1 | 2014 | 1627 | 0.080 |
Why?
|
| Imidazoles | 1 | 2015 | 1180 | 0.080 |
Why?
|
| Cytokines | 1 | 2023 | 7343 | 0.080 |
Why?
|
| Male | 17 | 2021 | 359744 | 0.080 |
Why?
|
| LDL-Receptor Related Proteins | 1 | 2008 | 118 | 0.080 |
Why?
|
| Signal Transduction | 3 | 2009 | 23376 | 0.080 |
Why?
|
| Receptors, AMPA | 1 | 2010 | 323 | 0.080 |
Why?
|
| Ubiquitin-Protein Ligases | 2 | 2015 | 1889 | 0.070 |
Why?
|
| Intracellular Signaling Peptides and Proteins | 2 | 2009 | 2873 | 0.070 |
Why?
|
| Presynaptic Terminals | 1 | 2009 | 301 | 0.070 |
Why?
|
| Female | 18 | 2021 | 391270 | 0.070 |
Why?
|
| Reserpine | 1 | 2007 | 60 | 0.070 |
Why?
|
| Case-Control Studies | 3 | 2021 | 22053 | 0.070 |
Why?
|
| Tissue Distribution | 2 | 2014 | 2262 | 0.070 |
Why?
|
| Heterozygote | 1 | 2014 | 2798 | 0.070 |
Why?
|
| Metabolome | 1 | 2014 | 982 | 0.070 |
Why?
|
| Alternative Splicing | 1 | 2011 | 1091 | 0.070 |
Why?
|
| Tritium | 1 | 2007 | 707 | 0.070 |
Why?
|
| Neurodegenerative Diseases | 1 | 2015 | 1084 | 0.070 |
Why?
|
| Receptors, LDL | 1 | 2008 | 488 | 0.070 |
Why?
|
| Embryonic Stem Cells | 1 | 2013 | 1262 | 0.070 |
Why?
|
| Spinal Cord | 1 | 2014 | 1817 | 0.070 |
Why?
|
| Dendritic Spines | 1 | 2007 | 243 | 0.060 |
Why?
|
| Prosencephalon | 1 | 2007 | 305 | 0.060 |
Why?
|
| Naltrexone | 1 | 2007 | 317 | 0.060 |
Why?
|
| Brain Chemistry | 1 | 2008 | 959 | 0.060 |
Why?
|
| Acid Ceramidase | 1 | 2023 | 21 | 0.060 |
Why?
|
| Glutamic Acid | 1 | 2009 | 1167 | 0.050 |
Why?
|
| Pyridines | 1 | 2015 | 2879 | 0.050 |
Why?
|
| Blood-Brain Barrier | 1 | 2009 | 1019 | 0.050 |
Why?
|
| Oxidopamine | 2 | 2015 | 172 | 0.050 |
Why?
|
| Protein Subunits | 1 | 2006 | 943 | 0.050 |
Why?
|
| Injections, Intraventricular | 2 | 2014 | 225 | 0.050 |
Why?
|
| Gene Expression | 5 | 2015 | 7588 | 0.050 |
Why?
|
| Narcotic Antagonists | 1 | 2007 | 583 | 0.050 |
Why?
|
| Membrane Proteins | 2 | 2009 | 7850 | 0.050 |
Why?
|
| Aged, 80 and over | 3 | 2021 | 58995 | 0.040 |
Why?
|
| Cells, Cultured | 3 | 2018 | 18957 | 0.040 |
Why?
|
| Cohort Studies | 2 | 2020 | 41335 | 0.040 |
Why?
|
| Thapsigargin | 1 | 2018 | 102 | 0.040 |
Why?
|
| Hydrolases | 1 | 2019 | 146 | 0.040 |
Why?
|
| Transfection | 3 | 2014 | 5781 | 0.040 |
Why?
|
| Phosphorylation | 2 | 2008 | 8313 | 0.040 |
Why?
|
| Synaptic Vesicles | 2 | 2010 | 190 | 0.040 |
Why?
|
| Locomotion | 2 | 2013 | 387 | 0.040 |
Why?
|
| Analysis of Variance | 1 | 2007 | 6238 | 0.040 |
Why?
|
| Apolipoproteins E | 1 | 2023 | 1436 | 0.040 |
Why?
|
| Histones | 1 | 2008 | 2583 | 0.040 |
Why?
|
| Oligonucleotides, Antisense | 1 | 2019 | 459 | 0.030 |
Why?
|
| Dopamine Agents | 2 | 2008 | 189 | 0.030 |
Why?
|
| RNA, Messenger | 4 | 2014 | 12766 | 0.030 |
Why?
|
| Aged | 5 | 2021 | 169152 | 0.030 |
Why?
|
| Chromatin | 1 | 2008 | 2938 | 0.030 |
Why?
|
| Valinomycin | 1 | 2015 | 17 | 0.030 |
Why?
|
| Benzodiazepinones | 1 | 2015 | 50 | 0.030 |
Why?
|
| Mitochondria | 2 | 2019 | 3600 | 0.030 |
Why?
|
| Membrane Potential, Mitochondrial | 1 | 2015 | 296 | 0.030 |
Why?
|
| Risk Factors | 2 | 2019 | 74359 | 0.030 |
Why?
|
| TOR Serine-Threonine Kinases | 1 | 2023 | 2058 | 0.030 |
Why?
|
| Cyclic AMP | 2 | 2009 | 1456 | 0.030 |
Why?
|
| Middle Aged | 5 | 2021 | 220352 | 0.030 |
Why?
|
| Complement Activation | 1 | 2015 | 446 | 0.030 |
Why?
|
| Vimentin | 1 | 2014 | 255 | 0.030 |
Why?
|
| Cell Line | 3 | 2015 | 15620 | 0.030 |
Why?
|
| Endoplasmic Reticulum | 1 | 2018 | 1132 | 0.030 |
Why?
|
| Astrocytes | 1 | 2020 | 1338 | 0.030 |
Why?
|
| Hydrogen Peroxide | 1 | 2014 | 732 | 0.020 |
Why?
|
| Dependovirus | 1 | 2015 | 709 | 0.020 |
Why?
|
| 3,4-Dihydroxyphenylacetic Acid | 1 | 2009 | 63 | 0.020 |
Why?
|
| Leupeptins | 1 | 2009 | 113 | 0.020 |
Why?
|
| Eye | 1 | 2013 | 710 | 0.020 |
Why?
|
| Lentivirus Infections | 1 | 2009 | 11 | 0.020 |
Why?
|
| Mutation, Missense | 1 | 2018 | 2566 | 0.020 |
Why?
|
| Ubiquitin | 1 | 2014 | 838 | 0.020 |
Why?
|
| Synaptic Transmission | 1 | 2015 | 1171 | 0.020 |
Why?
|
| Gene Transfer Techniques | 1 | 2014 | 1204 | 0.020 |
Why?
|
| Animals, Genetically Modified | 1 | 2013 | 1553 | 0.020 |
Why?
|
| Random Allocation | 1 | 2013 | 2394 | 0.020 |
Why?
|
| Animals, Newborn | 1 | 2014 | 2672 | 0.020 |
Why?
|
| Proto-Oncogene Proteins c-myc | 1 | 2014 | 995 | 0.020 |
Why?
|
| Microdialysis | 1 | 2008 | 160 | 0.020 |
Why?
|
| Enkephalins | 1 | 2008 | 139 | 0.020 |
Why?
|
| Ventral Tegmental Area | 1 | 2009 | 134 | 0.020 |
Why?
|
| Protein Kinases | 1 | 2015 | 1612 | 0.020 |
Why?
|
| Stress, Physiological | 1 | 2015 | 1398 | 0.020 |
Why?
|
| Surface Plasmon Resonance | 1 | 2008 | 265 | 0.020 |
Why?
|
| Autophagy | 1 | 2015 | 1337 | 0.020 |
Why?
|
| Tyrosine 3-Monooxygenase | 1 | 2008 | 370 | 0.020 |
Why?
|
| Mice, Inbred NOD | 1 | 2011 | 1837 | 0.020 |
Why?
|
| Dynamins | 1 | 2007 | 138 | 0.020 |
Why?
|
| Protein Interaction Domains and Motifs | 1 | 2008 | 453 | 0.020 |
Why?
|
| Receptors, Glutamate | 1 | 2007 | 229 | 0.020 |
Why?
|
| Drosophila | 1 | 2013 | 1492 | 0.020 |
Why?
|
| Immunoprecipitation | 1 | 2008 | 877 | 0.020 |
Why?
|
| Receptors, Dopamine D2 | 1 | 2008 | 485 | 0.020 |
Why?
|
| Mice, SCID | 1 | 2011 | 2627 | 0.020 |
Why?
|
| Gadolinium DTPA | 1 | 2009 | 823 | 0.020 |
Why?
|
| Amphetamine | 1 | 2007 | 224 | 0.020 |
Why?
|
| Genetic Vectors | 1 | 2015 | 3380 | 0.020 |
Why?
|
| Extracellular Signal-Regulated MAP Kinases | 1 | 2008 | 616 | 0.020 |
Why?
|
| Protein Binding | 2 | 2008 | 9335 | 0.020 |
Why?
|
| Methylation | 1 | 2008 | 1082 | 0.020 |
Why?
|
| Acetylation | 1 | 2008 | 1062 | 0.020 |
Why?
|
| Protein Interaction Mapping | 1 | 2008 | 617 | 0.020 |
Why?
|
| Cell Differentiation | 2 | 2013 | 11481 | 0.020 |
Why?
|
| Immunohistochemistry | 2 | 2009 | 11071 | 0.020 |
Why?
|
| Fluorescent Antibody Technique | 1 | 2009 | 2471 | 0.010 |
Why?
|
| Protein Precursors | 1 | 2008 | 1134 | 0.010 |
Why?
|
| Cerebellum | 1 | 2011 | 1496 | 0.010 |
Why?
|
| Species Specificity | 1 | 2008 | 2418 | 0.010 |
Why?
|
| Plasmids | 1 | 2009 | 2275 | 0.010 |
Why?
|
| Pyrimidines | 1 | 2015 | 3016 | 0.010 |
Why?
|
| Microscopy, Confocal | 1 | 2009 | 1972 | 0.010 |
Why?
|
| Promoter Regions, Genetic | 1 | 2014 | 5785 | 0.010 |
Why?
|
| Embryo, Mammalian | 1 | 2008 | 1674 | 0.010 |
Why?
|
| Carcinoma | 1 | 2014 | 2331 | 0.010 |
Why?
|
| Mice, Knockout | 2 | 2009 | 14372 | 0.010 |
Why?
|
| Endocytosis | 1 | 2007 | 959 | 0.010 |
Why?
|
| Dose-Response Relationship, Drug | 1 | 2014 | 10827 | 0.010 |
Why?
|
| Chromosome Aberrations | 1 | 2008 | 1764 | 0.010 |
Why?
|
| Models, Neurological | 1 | 2009 | 1758 | 0.010 |
Why?
|
| Blotting, Western | 1 | 2009 | 5039 | 0.010 |
Why?
|
| Microscopy, Fluorescence | 1 | 2008 | 2651 | 0.010 |
Why?
|
| Proteins | 1 | 2015 | 6029 | 0.010 |
Why?
|
| Neuroblastoma | 1 | 2008 | 1252 | 0.010 |
Why?
|
| Cell Membrane | 1 | 2010 | 3682 | 0.010 |
Why?
|
| Protein Processing, Post-Translational | 1 | 2008 | 1974 | 0.010 |
Why?
|
| Time Factors | 2 | 2014 | 40165 | 0.010 |
Why?
|
| Protein Structure, Tertiary | 1 | 2007 | 3800 | 0.010 |
Why?
|
| Amino Acid Sequence | 1 | 2011 | 13451 | 0.010 |
Why?
|
| Binding Sites | 1 | 2008 | 6048 | 0.010 |
Why?
|
| Cerebral Cortex | 1 | 2015 | 5761 | 0.010 |
Why?
|
| Molecular Sequence Data | 1 | 2011 | 17624 | 0.010 |
Why?
|
| Graft Survival | 1 | 2008 | 3794 | 0.010 |
Why?
|
| Cell Line, Tumor | 1 | 2014 | 16939 | 0.010 |
Why?
|
| Learning | 1 | 2007 | 1739 | 0.010 |
Why?
|
| DNA-Binding Proteins | 1 | 2014 | 9585 | 0.010 |
Why?
|
| Gene Expression Profiling | 1 | 2009 | 9411 | 0.010 |
Why?
|
| Adult | 2 | 2019 | 219994 | 0.010 |
Why?
|
| Positron-Emission Tomography | 1 | 2008 | 6465 | 0.010 |
Why?
|
| Mental Disorders | 1 | 2007 | 6796 | 0.000 |
Why?
|
| Magnetic Resonance Imaging | 1 | 2009 | 36290 | 0.000 |
Why?
|
| Treatment Outcome | 1 | 2008 | 65017 | 0.000 |
Why?
|