"Microglia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The third type of glial cell, along with astrocytes and oligodendrocytes (which together form the macroglia). Microglia vary in appearance depending on developmental stage, functional state, and anatomical location; subtype terms include ramified, perivascular, ameboid, resting, and activated. Microglia clearly are capable of phagocytosis and play an important role in a wide spectrum of neuropathologies. They have also been suggested to act in several other roles including in secretion (e.g., of cytokines and neural growth factors), in immunological processing (e.g., antigen presentation), and in central nervous system development and remodeling.
Below are MeSH descriptors whose meaning is more general than "Microglia".
Below are MeSH descriptors whose meaning is more specific than "Microglia".
This graph shows the total number of publications written about "Microglia" by people in Harvard Catalyst Profiles by year, and whether "Microglia" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 1 | 1 | 2 |
1996 | 4 | 1 | 5 |
1997 | 6 | 1 | 7 |
1998 | 6 | 8 | 14 |
1999 | 5 | 2 | 7 |
2000 | 1 | 4 | 5 |
2001 | 3 | 4 | 7 |
2002 | 5 | 6 | 11 |
2003 | 8 | 2 | 10 |
2004 | 3 | 2 | 5 |
2005 | 9 | 4 | 13 |
2006 | 9 | 9 | 18 |
2007 | 10 | 7 | 17 |
2008 | 18 | 6 | 24 |
2009 | 8 | 8 | 16 |
2010 | 5 | 9 | 14 |
2011 | 10 | 9 | 19 |
2012 | 10 | 7 | 17 |
2013 | 14 | 8 | 22 |
2014 | 13 | 9 | 22 |
2015 | 24 | 12 | 36 |
2016 | 22 | 6 | 28 |
2017 | 29 | 19 | 48 |
2018 | 39 | 19 | 58 |
2019 | 34 | 30 | 64 |
2020 | 37 | 19 | 56 |
2021 | 31 | 31 | 62 |
2022 | 17 | 22 | 39 |
2023 | 20 | 34 | 54 |
2024 | 0 | 3 | 3 |
Below are the most recent publications written about "Microglia" by people in Profiles.
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Sodium oligomannate alters gut microbiota, reduces cerebral amyloidosis and reactive microglia in a sex-specific manner. Mol Neurodegener. 2024 Feb 17; 19(1):18.
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Unraveling the dual nature of brain CD8+ T cells in Alzheimer's disease. Mol Neurodegener. 2024 Feb 14; 19(1):16.
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Early modulation of the gut microbiome by female sex hormones alters amyloid pathology and microglial function. Sci Rep. 2024 01 21; 14(1):1827.
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ATM-deficiency-induced microglial activation promotes neurodegeneration in ataxia-telangiectasia. Cell Rep. 2024 01 23; 43(1):113622.
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Sleep restoration by optogenetic targeting of GABAergic neurons reprograms microglia and ameliorates pathological phenotypes in an Alzheimer's disease model. Mol Neurodegener. 2023 Dec 01; 18(1):93.
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Microglial function, INPP5D/SHIP1 signaling, and NLRP3 inflammasome activation: implications for Alzheimer's disease. Mol Neurodegener. 2023 Nov 29; 18(1):89.
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INPP5D regulates inflammasome activation in human microglia. Nat Commun. 2023 Nov 29; 14(1):7552.
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Clearing and replacing tissue-resident myeloid cells with an anti-CD45 antibody-drug conjugate. Blood Adv. 2023 11 28; 7(22):6964-6973.
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Gonadal hormones impart male-biased behavioral vulnerabilities to immune activation via microglial mitochondrial function. Brain Behav Immun. 2024 01; 115:680-695.
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Alzheimer's defense: brain CD8+ T cells in action. Trends Immunol. 2023 Dec; 44(12):936-937.