Valinomycin

"Valinomycin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A cyclododecadepsipeptide ionophore antibiotic produced by Streptomyces fulvissimus and related to the enniatins. It is composed of 3 moles each of L-valine, D-alpha-hydroxyisovaleric acid, D-valine, and L-lactic acid linked alternately to form a 36-membered ring. (From Merck Index, 11th ed) Valinomycin is a potassium selective ionophore and is commonly used as a tool in biochemical studies.

Descriptor ID

D014634

MeSH Number(s)

D04.345.566.297.500

D12.644.641.297.500

Concept/Terms

Valinomycin

Below are MeSH descriptors whose meaning is more general than "Valinomycin".

Chemicals and Drugs [D]
Polycyclic Compounds [D04]
Macrocyclic Compounds [D04.345]
Peptides, Cyclic [D04.345.566]
Depsipeptides [D04.345.566.297]
Valinomycin [D04.345.566.297.500]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Peptides, Cyclic [D12.644.641]
Depsipeptides [D12.644.641.297]
Valinomycin [D12.644.641.297.500]

Below are MeSH descriptors whose meaning is related to "Valinomycin".

Below are MeSH descriptors whose meaning is more specific than "Valinomycin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Valinomycin" by people in Harvard Catalyst Profiles by year, and whether "Valinomycin" was a major or minor topic of these publication.

Bar chart showing 5 publications over 5 distinct years, with a maximum of 1 publications in 2003 and 2008 and 2014 and 2015 and 2016

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
2003	1	1
2008	1	1
2014	1	1
2015	1	1
2016	1	1

Below are the most recent publications written about "Valinomycin" by people in Profiles.

Trapping biosynthetic acyl-enzyme intermediates with encoded 2,3-diaminopropionic acid. Nature. 2019 01; 565(7737):112-117.

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Direct observation of proton pumping by a eukaryotic P-type ATPase. Science. 2016 Mar 25; 351(6280):1469-73.

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Fibroblast Biomarkers of Sporadic Parkinson's Disease and LRRK2 Kinase Inhibition. Mol Neurobiol. 2016 10; 53(8):5161-77.

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A chemical genetic approach to probe the function of PINK1 in regulating mitochondrial dynamics. Cell Res. 2015 Mar; 25(3):394-7.

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Membrane potential-dependent uptake of 18F-triphenylphosphonium--a new voltage sensor as an imaging agent for detecting burn-induced apoptosis. J Surg Res. 2014 May 15; 188(2):473-9.

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Functional reconstitution of influenza A M2(22-62). Biochim Biophys Acta. 2011 Feb; 1808(2):516-21.

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Reduced DIDS-sensitive chloride conductance in Ae1-/- mouse erythrocytes. Blood Cells Mol Dis. 2008 Jul-Aug; 41(1):22-34.

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Characterization of the cereulide NRPS alpha-hydroxy acid specifying modules: activation of alpha-keto acids and chiral reduction on the assembly line. J Am Chem Soc. 2006 Aug 23; 128(33):10698-9.

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Cardiolipin biosynthesis and mitochondrial respiratory chain function are interdependent. J Biol Chem. 2004 Oct 08; 279(41):42612-8.

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Ion transport coupled to terminal oxidase functioning in the extremely alkaliphilic halotolerant bacterium Thioalkalivibrio. Biochemistry (Mosc). 2003 Apr; 68(4):385-90.

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