"Astrocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.
Below are MeSH descriptors whose meaning is more general than "Astrocytes".
Below are MeSH descriptors whose meaning is more specific than "Astrocytes".
This graph shows the total number of publications written about "Astrocytes" by people in Harvard Catalyst Profiles by year, and whether "Astrocytes" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 5 | 2 | 7 |
1995 | 2 | 4 | 6 |
1996 | 5 | 4 | 9 |
1997 | 6 | 6 | 12 |
1998 | 8 | 5 | 13 |
1999 | 11 | 6 | 17 |
2000 | 11 | 7 | 18 |
2001 | 5 | 6 | 11 |
2002 | 14 | 10 | 24 |
2003 | 3 | 13 | 16 |
2004 | 14 | 13 | 27 |
2005 | 11 | 8 | 19 |
2006 | 14 | 10 | 24 |
2007 | 6 | 18 | 24 |
2008 | 12 | 15 | 27 |
2009 | 7 | 19 | 26 |
2010 | 16 | 11 | 27 |
2011 | 14 | 9 | 23 |
2012 | 21 | 21 | 42 |
2013 | 14 | 12 | 26 |
2014 | 17 | 19 | 36 |
2015 | 23 | 10 | 33 |
2016 | 16 | 12 | 28 |
2017 | 27 | 17 | 44 |
2018 | 22 | 21 | 43 |
2019 | 23 | 22 | 45 |
2020 | 21 | 23 | 44 |
2021 | 24 | 11 | 35 |
2022 | 10 | 16 | 26 |
2023 | 14 | 19 | 33 |
2024 | 1 | 0 | 1 |
Below are the most recent publications written about "Astrocytes" by people in Profiles.
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The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology. Nat Immunol. 2024 Mar; 25(3):432-447.
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Neuroinflammation: An astrocyte perspective. Sci Transl Med. 2023 11 08; 15(721):eadi7828.
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Tau Oligomer-Containing Synapse Elimination by Microglia and Astrocytes in Alzheimer Disease. JAMA Neurol. 2023 Nov 01; 80(11):1209-1221.
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Astrocytes of the optic nerve exhibit a region-specific and temporally distinct response to elevated intraocular pressure. Mol Neurodegener. 2023 Sep 27; 18(1):68.
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Rapid isolation of intact retinal astrocytes: a novel approach. Acta Neuropathol Commun. 2023 09 25; 11(1):154.
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Astrocytes in Parkinson's Disease: From Role to Possible Intervention. Cells. 2023 09 22; 12(19).
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Copper induces neuron-sparing, ferredoxin 1-independent astrocyte toxicity mediated by oxidative stress. J Neurochem. 2023 10; 167(2):277-295.
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Astrocytes on steroids binge on synapses to cope with stress. Immunity. 2023 09 12; 56(9):1983-1985.
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PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation. Nat Commun. 2023 09 09; 14(1):5555.
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Irisin reduces amyloid-ß by inducing the release of neprilysin from astrocytes following downregulation of ERK-STAT3 signaling. Neuron. 2023 11 15; 111(22):3619-3633.e8.