"Poly I-C" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Interferon inducer consisting of a synthetic, mismatched double-stranded RNA. The polymer is made of one strand each of polyinosinic acid and polycytidylic acid.
MeSH Number(s)
D13.695.578.550.560.600
D13.695.578.550.650.600
Concept/Terms
Poly I-C- Poly I-C
- Poly I C
- Polyinosinic-Polycytidylic Acid
- Polyinosinic Polycytidylic Acid
- Polyribose Inosin-Cytidil
- Inosin-Cytidil, Polyribose
- Polyribose Inosin Cytidil
- Poly(rI).Poly(rC)
Below are MeSH descriptors whose meaning is more general than "Poly I-C".
Below are MeSH descriptors whose meaning is more specific than "Poly I-C".
This graph shows the total number of publications written about "Poly I-C" by people in Harvard Catalyst Profiles by year, and whether "Poly I-C" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 1995 | 0 | 1 | 1 |
| 1996 | 1 | 1 | 2 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 5 | 5 |
| 2009 | 0 | 5 | 5 |
| 2010 | 3 | 5 | 8 |
| 2011 | 1 | 2 | 3 |
| 2012 | 1 | 3 | 4 |
| 2013 | 1 | 2 | 3 |
| 2014 | 1 | 2 | 3 |
| 2015 | 0 | 1 | 1 |
| 2016 | 4 | 3 | 7 |
| 2017 | 2 | 3 | 5 |
| 2018 | 0 | 4 | 4 |
| 2019 | 1 | 1 | 2 |
| 2020 | 2 | 5 | 7 |
| 2021 | 0 | 3 | 3 |
| 2022 | 0 | 3 | 3 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Poly I-C" by people in Profiles.
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Hybrid LNP Prime Dendritic Cells for Nucleotide Delivery. Adv Sci (Weinh). 2023 11; 10(33):e2303576.
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Cold exposure impairs extracellular vesicle swarm-mediated nasal antiviral immunity. J Allergy Clin Immunol. 2023 02; 151(2):509-525.e8.
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Investigating the "two-hit hypothesis": Effects of prenatal maternal immune activation and adolescent cannabis use on neurodevelopment in mice. Prog Neuropsychopharmacol Biol Psychiatry. 2023 01 10; 120:110642.
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Poly I:C and STING agonist-primed DC increase lymphoid tissue polyfunctional HIV-1-specific CD8+ T cells and limit CD4+ T-cell loss in BLT mice. Eur J Immunol. 2022 03; 52(3):447-461.
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Macrophages from Rosa26-Integrated Cas9-Expressing C57BL/6J Mice Have a Putative TRIF-Mediated Defect in the TLR-3/4 Signaling. Immunohorizons. 2021 10 19; 5(10):818-829.
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Intratumoral combination therapy with poly(I:C) and resiquimod synergistically triggers tumor-associated macrophages for effective systemic antitumoral immunity. J Immunother Cancer. 2021 09; 9(9).
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Caspase-8 deficiency induces a switch from TLR3 induced apoptosis to lysosomal cell death in neuroblastoma. Sci Rep. 2021 05 19; 11(1):10609.
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Early or Late Gestational Exposure to Maternal Immune Activation Alters Neurodevelopmental Trajectories in Mice: An Integrated Neuroimaging, Behavioral, and Transcriptional Study. Biol Psychiatry. 2021 09 01; 90(5):328-341.
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Extracellular cyclic dinucleotides induce polarized responses in barrier epithelial cells by adenosine signaling. Proc Natl Acad Sci U S A. 2020 11 03; 117(44):27502-27508.
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Increased RNA editing in maternal immune activation model of neurodevelopmental disease. Nat Commun. 2020 10 16; 11(1):5236.