Harvard Catalyst Profiles

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John Gerard Clohessy, Ph.D.

Concepts (338)

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Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
PTEN Phosphohydrolase14202011170.810 Why?
Drug Evaluation, Preclinical3201513310.410 Why?
Tumor Suppressor Protein p538201829480.350 Why?
TOR Serine-Threonine Kinases4201620600.340 Why?
Neoplasm Proteins4202136010.320 Why?
Prostatic Neoplasms112020110940.310 Why?
Leukemia, Promyelocytic, Acute220212490.300 Why?
Drug Resistance, Neoplasm7202153290.300 Why?
Tumor Suppressor Proteins4201928010.290 Why?
Proto-Oncogene Proteins c-akt7202424560.290 Why?
Xenograft Model Antitumor Assays8202436070.280 Why?
Disease Models, Animal112020183300.280 Why?
Mice412024818890.260 Why?
Anilides220204130.260 Why?
Antineoplastic Agents72024136430.250 Why?
BH3 Interacting Domain Death Agonist Protein12005880.250 Why?
Carcinoma, Non-Small-Cell Lung6202453870.250 Why?
Cytochromes c120051730.240 Why?
Ribosomal Protein S6 Kinases, 70-kDa220181020.240 Why?
Cell Line, Tumor212024170880.230 Why?
Pericytes220182980.220 Why?
RNA, Ribosomal220192270.220 Why?
Animals4720241689300.210 Why?
Indoles3201918340.210 Why?
Pantothenic Acid12022170.210 Why?
Nuclear Proteins6201957950.200 Why?
Coenzyme A12022390.200 Why?
Neoplasm Metastasis4201848910.200 Why?
Proto-Oncogene Proteins c-bcl-22200514050.190 Why?
Gene Expression Regulation, Neoplastic13202186210.190 Why?
Phosphatidylinositol 3-Kinase120221250.190 Why?
Computational Biology1201335640.190 Why?
Clinical Trials as Topic2201580450.180 Why?
Caspases120048810.180 Why?
Nipples120232270.180 Why?
Ubiquitin-Protein Ligases2202118990.180 Why?
Androgen Receptor Antagonists120211230.170 Why?
Sesquiterpenes120211750.170 Why?
Lipogenesis220202170.170 Why?
Glucose Transporter Type 312019160.170 Why?
Phosphatidylinositol 3-Kinases4202128810.160 Why?
Lung Neoplasms62024134850.160 Why?
Trans-Activators1200928550.160 Why?
Dyskeratosis Congenita12019700.160 Why?
Quinolines120247690.160 Why?
Mammary Neoplasms, Experimental120214960.160 Why?
Mutation102021302130.160 Why?
Thyroid Neoplasms3201823550.150 Why?
Cytoplasm3201315050.150 Why?
Sterol Regulatory Element Binding Proteins12018250.150 Why?
Databases, Factual1201380660.150 Why?
Organoids220217400.150 Why?
Caveolin 1120192550.150 Why?
Protein Phosphatase 1120181350.140 Why?
Anticarcinogenic Agents120192510.140 Why?
Lipoylation12018870.140 Why?
Cell Proliferation102024104450.140 Why?
Pyridines2202028880.140 Why?
RNA Processing, Post-Transcriptional120193930.140 Why?
Growth and Development12016460.140 Why?
Molecular Targeted Therapy4202128230.140 Why?
Signal Transduction142022236190.140 Why?
Leukemia, Myeloid, Acute5201936360.130 Why?
Apoptosis5202195130.130 Why?
Cell Cycle Proteins2202434390.130 Why?
Proto-Oncogene Proteins B-raf2201820560.130 Why?
Positive Transcriptional Elongation Factor B12016420.130 Why?
DNA, Intergenic120161080.130 Why?
Neoplasms52019223500.130 Why?
Mice, Transgenic10202195470.130 Why?
Tretinoin120195240.130 Why?
RNA-Binding Proteins2201618840.130 Why?
Proteomics2202439140.130 Why?
Benzimidazoles120218620.130 Why?
Fertility120207700.130 Why?
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors120183260.130 Why?
HMGB1 Protein120171400.120 Why?
Cholesterol1202429030.120 Why?
Genetic Pleiotropy120161820.120 Why?
Pyrazines1202112040.120 Why?
RNA, Messenger52019127910.120 Why?
Animal Husbandry12015640.120 Why?
Chemokine CXCL12120174570.120 Why?
Hematopoiesis1200420600.120 Why?
Transcription Factors52021121500.120 Why?
Receptors, Androgen1202110890.120 Why?
Transforming Growth Factor beta1120186370.120 Why?
Mice, SCID4202126280.120 Why?
Elafin12014290.120 Why?
Phthalazines120173970.120 Why?
Cell Transformation, Neoplastic5201828390.110 Why?
Multiprotein Complexes3201611100.110 Why?
Hemangiopericytoma12014710.110 Why?
Hematopoietic Stem Cells2201934080.110 Why?
Epigenomics120199590.110 Why?
Proto-Oncogene Proteins c-myc120199960.110 Why?
Phosphotransferases (Alcohol Group Acceptor)220224340.110 Why?
RNA2202127150.110 Why?
Protein Kinase Inhibitors4202056900.110 Why?
Public Sector120152650.110 Why?
Mice, Knockout82021144710.110 Why?
Genes, Neoplasm120153690.110 Why?
Receptor Protein-Tyrosine Kinases1202016210.110 Why?
Pancreatic Neoplasms2202154440.110 Why?
Phosphoric Monoester Hydrolases120154150.100 Why?
Proto-Oncogene Proteins p21(ras)1202117620.100 Why?
Drug Repositioning120152460.100 Why?
Isocitrate Dehydrogenase120199500.100 Why?
Carcinoma, Pancreatic Ductal2202117570.100 Why?
NF-kappa B1202124930.100 Why?
Therapies, Investigational120131100.100 Why?
Poly(ADP-ribose) Polymerases120144280.100 Why?
Gallbladder Neoplasms120141900.100 Why?
Eukaryotic Initiation Factors12012830.100 Why?
Muscles1201615760.100 Why?
Enzyme Activation1201835870.100 Why?
Private Sector120153960.100 Why?
Adenocarcinoma, Follicular120153230.090 Why?
Humans5020247667660.090 Why?
DNA-Binding Proteins2201996110.090 Why?
Germ-Line Mutation1201918850.090 Why?
Epithelial Cells2202136910.090 Why?
MAP Kinase Signaling System1201814910.090 Why?
Neutrophils2202037820.090 Why?
Histones1202125930.090 Why?
Naphthyridines120121840.090 Why?
Ribosomes120134960.090 Why?
fms-Like Tyrosine Kinase 3120134960.080 Why?
Myeloid Cells220188380.080 Why?
Lysosomes320219370.080 Why?
Hydroxymethylglutaryl-CoA Reductase Inhibitors1202432500.080 Why?
Breast Neoplasms42023211620.080 Why?
Oncogene Proteins220167150.080 Why?
Chromatin1202129770.080 Why?
Nanoparticles1202019660.080 Why?
HEK293 Cells4201942760.080 Why?
Interprofessional Relations120159980.080 Why?
Drug Synergism2202417560.080 Why?
Oncogenes2202112310.080 Why?
Purines120126150.080 Why?
Sarcoma1201918020.070 Why?
Immunotherapy2202147470.070 Why?
Drug Approval120158200.070 Why?
Medical Informatics120157440.070 Why?
Regeneration1201615200.070 Why?
Gene Expression Regulation32021119200.070 Why?
Tumor Microenvironment4202439440.070 Why?
DNA1202172080.070 Why?
Drug Discovery1201510650.070 Why?
Piperazines1201725470.070 Why?
Gene Expression Regulation, Enzymologic1201111680.070 Why?
Embryonic Stem Cells1201312430.070 Why?
Mass Spectrometry3202221980.060 Why?
Gene Expression Regulation, Leukemic120096580.060 Why?
Reverse Transcriptase Polymerase Chain Reaction3201345700.060 Why?
bcl-2 Homologous Antagonist-Killer Protein12005710.060 Why?
Androgens1201312800.060 Why?
Open Reading Frames220208180.060 Why?
Models, Biological6201894610.060 Why?
Gene Expression Profiling5202195250.060 Why?
Genome, Human1201844430.060 Why?
Down-Regulation1201229310.060 Why?
Two-Hybrid System Techniques120054630.060 Why?
Mice, Nude2202136160.060 Why?
TNF-Related Apoptosis-Inducing Ligand120051950.060 Why?
Peptides1201643440.060 Why?
bcl-2-Associated X Protein120052810.060 Why?
Sulfonamides1201419820.060 Why?
Sterol Regulatory Element Binding Protein 212024580.060 Why?
Androgen Antagonists1201314110.060 Why?
Gene Knockout Techniques220198030.060 Why?
Angiogenesis Inhibitors1201420570.060 Why?
Mice, Inbred C57BL62019223520.060 Why?
Cyclin-Dependent Kinase Inhibitor p16120077050.060 Why?
Ubiquitination2201910070.060 Why?
Pyrimidines1201630430.050 Why?
RNA, Neoplasm120067470.050 Why?
Proteome1201318940.050 Why?
Mice, Inbred NOD2202118380.050 Why?
Male2120213641420.050 Why?
Keratin-712023550.050 Why?
Mitosis2202411760.050 Why?
Proteins3201860020.050 Why?
Endosomes220165210.050 Why?
Jurkat Cells120047400.050 Why?
Mutagenesis, Site-Directed1200516770.050 Why?
Acetyl Coenzyme A12022740.050 Why?
Tumor Cells, Cultured2202061040.050 Why?
Protein Stability120245780.050 Why?
Phosphorylation2202483070.050 Why?
Equilibrative Nucleoside Transporter 112021170.050 Why?
Telomerase120067500.050 Why?
Gene Amplification2201810880.050 Why?
Transforming Growth Factor beta1200919960.050 Why?
Blotting, Western2200950220.050 Why?
Gene Silencing3201815040.050 Why?
Diagnostic Imaging1201535310.050 Why?
RNA, Small Interfering2202134250.050 Why?
Gene Regulatory Networks2202117510.050 Why?
Cell Cycle2202429260.040 Why?
Gene Expression1201375850.040 Why?
Ki-67 Antigen120236300.040 Why?
Mice, Inbred ICR120213610.040 Why?
Apoptosis Regulatory Proteins1200511500.040 Why?
RNA, Small Nucleolar12019270.040 Why?
Hyperplasia1202311500.040 Why?
HeLa Cells1200530730.040 Why?
Spermatogenesis120202590.040 Why?
Leukemia1200715210.040 Why?
U937 Cells120192600.040 Why?
Amino Acid Motifs120219280.040 Why?
Protein Structure, Tertiary1200537570.040 Why?
Proto-Oncogenes120193210.040 Why?
Antineoplastic Combined Chemotherapy Protocols12019118720.040 Why?
COS Cells1202011350.040 Why?
Cysteine120228960.040 Why?
HL-60 Cells120183650.040 Why?
Melanoma1201657000.040 Why?
RNA Interference1200528270.030 Why?
Endocytosis120219510.030 Why?
Deoxycytidine120218860.030 Why?
Cell Communication1202416600.030 Why?
Methylation1201910740.030 Why?
K562 Cells120186450.030 Why?
Protein Isoforms1202117160.030 Why?
RNA Splicing120219030.030 Why?
Microfilament Proteins1202111290.030 Why?
Cytarabine120186960.030 Why?
Adenosine Triphosphate1202220010.030 Why?
Benzylamines120172510.030 Why?
Hematologic Neoplasms1200819260.030 Why?
Heterocyclic Compounds120172450.030 Why?
Carrier Proteins1200949240.030 Why?
High-Throughput Screening Assays120219380.030 Why?
Tumor Burden1202119000.030 Why?
Membrane Glycoproteins1200537020.030 Why?
Radiation Tolerance120174760.030 Why?
Tumor Necrosis Factor-alpha1200543490.030 Why?
Genetic Heterogeneity120187350.030 Why?
Microtubules1202010620.030 Why?
Protein Multimerization120199600.030 Why?
Alternative Splicing1201911030.030 Why?
Polysaccharides1202010200.030 Why?
Neoplasms, Experimental1201912270.030 Why?
Pharmacogenetics120186820.030 Why?
Lipid Metabolism1202218950.030 Why?
Heterozygote2201127950.030 Why?
Protein Binding1200593200.030 Why?
Exons1201923920.030 Why?
Cell Growth Processes120143810.030 Why?
Metabolic Networks and Pathways120188000.030 Why?
Administration, Oral1202140180.030 Why?
Metabolomics1202216750.030 Why?
Melanoma, Experimental120165570.030 Why?
Valine120144100.030 Why?
Adenosine Triphosphatases120168400.030 Why?
Neoplasm Invasiveness1202036090.030 Why?
Gene Duplication120133150.030 Why?
Nanostructures120175490.020 Why?
Cell Membrane1202136410.020 Why?
Testosterone1202324950.020 Why?
Organ Specificity1201619660.020 Why?
Lymphocytes, Tumor-Infiltrating1201811050.020 Why?
Genotype22018130360.020 Why?
Phenylthiohydantoin120132060.020 Why?
Transfection1201957540.020 Why?
Loss of Heterozygosity120136630.020 Why?
Endothelial Cells1202435810.020 Why?
Orchiectomy120134650.020 Why?
Adaptor Proteins, Signal Transducing1202129020.020 Why?
Amino Acids1201617110.020 Why?
BRCA1 Protein1201711550.020 Why?
Kaplan-Meier Estimate1202165120.020 Why?
Cell Line12004155630.020 Why?
Genes, myc120113910.020 Why?
Fatty Acids1201818060.020 Why?
Alleles2201368950.020 Why?
Zebrafish Proteins1201610180.020 Why?
Single-Cell Analysis1202125340.020 Why?
Female820243965200.020 Why?
Mammary Neoplasms, Animal120101220.020 Why?
Gene Knockdown Techniques1201316040.020 Why?
Pheochromocytoma120113270.020 Why?
Up-Regulation1201841420.020 Why?
Mice, Inbred CBA120094390.020 Why?
Cell Movement1202051990.020 Why?
Survival Analysis12021101000.020 Why?
Proto-Oncogene Proteins1202145220.020 Why?
Glutamic Acid1201411810.020 Why?
Mesenchymal Stem Cells1201916630.020 Why?
Energy Metabolism1201929030.020 Why?
Mammals1201311330.020 Why?
Nitriles120139810.020 Why?
Cells, Cultured22013189840.020 Why?
Cell Line, Transformed120098610.020 Why?
Glucose1201943400.020 Why?
Benzamides1201313750.020 Why?
Adenovirus E1A Proteins12007810.020 Why?
Treatment Outcome12013652730.020 Why?
Treatment Failure1201326590.020 Why?
Neoplasm Transplantation1201020120.020 Why?
Genes, Tumor Suppressor1201010570.020 Why?
Gene Dosage1201012110.020 Why?
Homozygote1201017750.020 Why?
Immunity, Innate1201730770.010 Why?
Zebrafish1201630350.010 Why?
B-Lymphocytes1201847840.010 Why?
Embryo, Mammalian1201016750.010 Why?
Cell Separation1200917180.010 Why?
Adenocarcinoma1202163590.010 Why?
Gene Deletion1201126690.010 Why?
Neoplastic Stem Cells1201113510.010 Why?
Macrophages1201857830.010 Why?
Protein Biosynthesis1201020930.010 Why?
Base Sequence12013124150.010 Why?
Transcription, Genetic1201676090.010 Why?
Amino Acid Sequence12013134110.010 Why?
Transplantation, Heterologous1201023910.010 Why?
Molecular Sequence Data12013176080.010 Why?
Lung12019100670.010 Why?
T-Lymphocytes12018102640.010 Why?
Models, Genetic1201034500.010 Why?
DNA Damage1201024670.010 Why?
Prognosis12020299480.010 Why?
Lymphoma, B-Cell120069450.010 Why?
Fibroblasts1201041660.010 Why?
Flow Cytometry1200958900.010 Why?
Promoter Regions, Genetic1200957890.010 Why?
Myelodysplastic Syndromes1200814040.010 Why?
Middle Aged220232232570.010 Why?
Neoplasm Recurrence, Local1201494040.010 Why?
Cell Differentiation12013116510.010 Why?
Aged, 80 and over12020595500.010 Why?
Colonic Neoplasms1200625340.010 Why?
Immunohistochemistry12006110610.010 Why?
Genetic Predisposition to Disease12010180750.000 Why?
Aged120201713430.000 Why?
Adult120202233070.000 Why?
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.