Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

John Gerard Clohessy, Ph.D.

Concepts (338)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
PTEN Phosphohydrolase14202011190.810 Why?
Drug Evaluation, Preclinical3201513390.410 Why?
Tumor Suppressor Protein p538201829520.360 Why?
TOR Serine-Threonine Kinases4201620660.340 Why?
Neoplasm Proteins4202136100.320 Why?
Prostatic Neoplasms112020112210.310 Why?
Leukemia, Promyelocytic, Acute220212490.300 Why?
Drug Resistance, Neoplasm7202153360.300 Why?
Tumor Suppressor Proteins4201928120.290 Why?
Proto-Oncogene Proteins c-akt7202424600.290 Why?
Xenograft Model Antitumor Assays8202436170.280 Why?
Disease Models, Animal112020183620.280 Why?
Mice412024820170.260 Why?
Anilides220204140.260 Why?
BH3 Interacting Domain Death Agonist Protein12005880.250 Why?
Antineoplastic Agents72024136970.250 Why?
Carcinoma, Non-Small-Cell Lung6202454220.250 Why?
Cytochromes c120051730.250 Why?
Ribosomal Protein S6 Kinases, 70-kDa220181030.240 Why?
Cell Line, Tumor212024171350.230 Why?
Pericytes220182990.220 Why?
RNA, Ribosomal220192270.220 Why?
Indoles3201918250.210 Why?
Animals4720241693370.210 Why?
Pantothenic Acid12022170.210 Why?
Nuclear Proteins6201958000.200 Why?
Coenzyme A12022390.200 Why?
Neoplasm Metastasis4201849210.200 Why?
Proto-Oncogene Proteins c-bcl-22200514090.200 Why?
Gene Expression Regulation, Neoplastic13202186340.190 Why?
Computational Biology1201335430.190 Why?
Phosphatidylinositol 3-Kinase120221260.190 Why?
Clinical Trials as Topic2201580510.180 Why?
Caspases120048810.180 Why?
Nipples120232300.180 Why?
Ubiquitin-Protein Ligases2202119010.180 Why?
Androgen Receptor Antagonists120211250.170 Why?
Sesquiterpenes120211770.170 Why?
Lipogenesis220202160.170 Why?
Glucose Transporter Type 312019160.170 Why?
Phosphatidylinositol 3-Kinases4202128840.160 Why?
Lung Neoplasms62024135760.160 Why?
Trans-Activators1200928560.160 Why?
Dyskeratosis Congenita12019700.160 Why?
Quinolines120247680.160 Why?
Mammary Neoplasms, Experimental120215060.160 Why?
Mutation102021302280.160 Why?
Thyroid Neoplasms3201823600.150 Why?
Cytoplasm3201315020.150 Why?
Sterol Regulatory Element Binding Proteins12018250.150 Why?
Databases, Factual1201380750.150 Why?
Caveolin 1120192550.150 Why?
Organoids220217460.150 Why?
Protein Phosphatase 1120181350.140 Why?
Anticarcinogenic Agents120192510.140 Why?
Lipoylation12018870.140 Why?
Cell Proliferation102024104780.140 Why?
Pyridines2202028890.140 Why?
RNA Processing, Post-Transcriptional120193930.140 Why?
Growth and Development12016460.140 Why?
Molecular Targeted Therapy4202128300.140 Why?
Signal Transduction142022236310.140 Why?
Leukemia, Myeloid, Acute5201936200.140 Why?
Apoptosis5202195160.130 Why?
Proto-Oncogene Proteins B-raf2201820580.130 Why?
Positive Transcriptional Elongation Factor B12016420.130 Why?
Cell Cycle Proteins2202434580.130 Why?
DNA, Intergenic120161080.130 Why?
Neoplasms52019223850.130 Why?
Mice, Transgenic10202195620.130 Why?
Tretinoin120195250.130 Why?
RNA-Binding Proteins2201618830.130 Why?
Proteomics2202439060.130 Why?
Benzimidazoles120218640.130 Why?
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors120183250.130 Why?
Fertility120207720.130 Why?
HMGB1 Protein120171410.130 Why?
Genetic Pleiotropy120161810.120 Why?
Cholesterol1202429120.120 Why?
Pyrazines1202112060.120 Why?
RNA, Messenger52019128050.120 Why?
Animal Husbandry12015640.120 Why?
Chemokine CXCL12120174570.120 Why?
Hematopoiesis1200420580.120 Why?
Transcription Factors52021121660.120 Why?
Receptors, Androgen1202110830.120 Why?
Transforming Growth Factor beta1120186370.120 Why?
Mice, SCID4202126320.120 Why?
Elafin12014300.120 Why?
Phthalazines120173970.120 Why?
Cell Transformation, Neoplastic5201828460.120 Why?
Multiprotein Complexes3201611100.110 Why?
Hemangiopericytoma12014710.110 Why?
Hematopoietic Stem Cells2201934070.110 Why?
Epigenomics120199590.110 Why?
Phosphotransferases (Alcohol Group Acceptor)220224340.110 Why?
Proto-Oncogene Proteins c-myc120199980.110 Why?
RNA2202127260.110 Why?
Protein Kinase Inhibitors4202057080.110 Why?
Public Sector120152660.110 Why?
Mice, Knockout82021144810.110 Why?
Genes, Neoplasm120153700.110 Why?
Receptor Protein-Tyrosine Kinases1202016280.110 Why?
Phosphoric Monoester Hydrolases120154130.110 Why?
Pancreatic Neoplasms2202154430.110 Why?
Proto-Oncogene Proteins p21(ras)1202117660.110 Why?
Drug Repositioning120152440.100 Why?
Isocitrate Dehydrogenase120199540.100 Why?
Carcinoma, Pancreatic Ductal2202117550.100 Why?
NF-kappa B1202124890.100 Why?
Therapies, Investigational120131110.100 Why?
Poly(ADP-ribose) Polymerases120144270.100 Why?
Gallbladder Neoplasms120141910.100 Why?
Eukaryotic Initiation Factors12012830.100 Why?
Enzyme Activation1201835870.100 Why?
Private Sector120153960.100 Why?
Muscles1201615820.100 Why?
Adenocarcinoma, Follicular120153260.090 Why?
Humans5020247683930.090 Why?
DNA-Binding Proteins2201996140.090 Why?
Germ-Line Mutation1201918850.090 Why?
Epithelial Cells2202136950.090 Why?
MAP Kinase Signaling System1201814930.090 Why?
Histones1202125920.090 Why?
Neutrophils2202037850.090 Why?
Naphthyridines120121810.090 Why?
Ribosomes120134990.090 Why?
fms-Like Tyrosine Kinase 3120134940.080 Why?
Myeloid Cells220188320.080 Why?
Lysosomes320219390.080 Why?
Hydroxymethylglutaryl-CoA Reductase Inhibitors1202432520.080 Why?
Breast Neoplasms42023211620.080 Why?
Chromatin1202129680.080 Why?
Oncogene Proteins220167180.080 Why?
HEK293 Cells4201942910.080 Why?
Nanoparticles1202019870.080 Why?
Interprofessional Relations120159970.080 Why?
Drug Synergism2202417620.080 Why?
Oncogenes2202112350.080 Why?
Purines120126150.080 Why?
Immunotherapy2202147380.070 Why?
Sarcoma1201918070.070 Why?
Drug Approval120158180.070 Why?
Medical Informatics120157400.070 Why?
Regeneration1201615250.070 Why?
Gene Expression Regulation32021119180.070 Why?
Tumor Microenvironment4202439390.070 Why?
DNA1202172110.070 Why?
Drug Discovery1201510670.070 Why?
Piperazines1201725520.070 Why?
Gene Expression Regulation, Enzymologic1201111690.070 Why?
Embryonic Stem Cells1201312490.070 Why?
Mass Spectrometry3202222010.060 Why?
Gene Expression Regulation, Leukemic120096560.060 Why?
bcl-2 Homologous Antagonist-Killer Protein12005710.060 Why?
Reverse Transcriptase Polymerase Chain Reaction3201345880.060 Why?
Androgens1201312850.060 Why?
Open Reading Frames220208120.060 Why?
Models, Biological6201894930.060 Why?
Gene Expression Profiling5202195100.060 Why?
Genome, Human1201844500.060 Why?
Down-Regulation1201229400.060 Why?
Two-Hybrid System Techniques120054610.060 Why?
TNF-Related Apoptosis-Inducing Ligand120051950.060 Why?
Mice, Nude2202136320.060 Why?
Peptides1201643530.060 Why?
bcl-2-Associated X Protein120052820.060 Why?
Sulfonamides1201419800.060 Why?
Sterol Regulatory Element Binding Protein 212024580.060 Why?
Androgen Antagonists1201314210.060 Why?
Angiogenesis Inhibitors1201420600.060 Why?
Gene Knockout Techniques220198080.060 Why?
Mice, Inbred C57BL62019223550.060 Why?
Cyclin-Dependent Kinase Inhibitor p16120077100.060 Why?
Ubiquitination2201910090.060 Why?
Pyrimidines1201630480.060 Why?
RNA, Neoplasm120067500.060 Why?
Proteome1201318810.050 Why?
Mice, Inbred NOD2202118390.050 Why?
Male2120213649020.050 Why?
Keratin-712023550.050 Why?
Mitosis2202411900.050 Why?
Proteins3201860060.050 Why?
Endosomes220165250.050 Why?
Jurkat Cells120047380.050 Why?
Mutagenesis, Site-Directed1200516820.050 Why?
Acetyl Coenzyme A12022740.050 Why?
Tumor Cells, Cultured2202061320.050 Why?
Protein Stability120245800.050 Why?
Phosphorylation2202483260.050 Why?
Equilibrative Nucleoside Transporter 112021170.050 Why?
Telomerase120067520.050 Why?
Gene Amplification2201810900.050 Why?
Transforming Growth Factor beta1200920030.050 Why?
Blotting, Western2200950370.050 Why?
Gene Silencing3201815030.050 Why?
Diagnostic Imaging1201535410.050 Why?
RNA, Small Interfering2202134340.050 Why?
Gene Regulatory Networks2202117530.050 Why?
Cell Cycle2202429380.040 Why?
Ki-67 Antigen120236280.040 Why?
Gene Expression1201375980.040 Why?
Mice, Inbred ICR120213630.040 Why?
Apoptosis Regulatory Proteins1200511510.040 Why?
RNA, Small Nucleolar12019270.040 Why?
Hyperplasia1202311530.040 Why?
HeLa Cells1200530880.040 Why?
Spermatogenesis120202590.040 Why?
U937 Cells120192600.040 Why?
Amino Acid Motifs120219290.040 Why?
Leukemia1200715260.040 Why?
Protein Structure, Tertiary1200537790.040 Why?
Proto-Oncogenes120193220.040 Why?
Antineoplastic Combined Chemotherapy Protocols12019118540.040 Why?
COS Cells1202011350.040 Why?
Cysteine120228950.040 Why?
HL-60 Cells120183640.040 Why?
Melanoma1201657050.040 Why?
RNA Interference1200528360.030 Why?
Endocytosis120219590.030 Why?
Deoxycytidine120218880.030 Why?
Methylation1201910760.030 Why?
Cell Communication1202416600.030 Why?
K562 Cells120186440.030 Why?
Protein Isoforms1202117030.030 Why?
RNA Splicing120219030.030 Why?
Microfilament Proteins1202111350.030 Why?
Cytarabine120186970.030 Why?
Adenosine Triphosphate1202220020.030 Why?
Benzylamines120172510.030 Why?
Hematologic Neoplasms1200819050.030 Why?
Heterocyclic Compounds120172450.030 Why?
Carrier Proteins1200949360.030 Why?
High-Throughput Screening Assays120219370.030 Why?
Tumor Burden1202119130.030 Why?
Membrane Glycoproteins1200537120.030 Why?
Radiation Tolerance120174780.030 Why?
Tumor Necrosis Factor-alpha1200543570.030 Why?
Genetic Heterogeneity120187370.030 Why?
Microtubules1202010710.030 Why?
Alternative Splicing1201910930.030 Why?
Protein Multimerization120199710.030 Why?
Polysaccharides1202010240.030 Why?
Pharmacogenetics120186830.030 Why?
Neoplasms, Experimental1201912320.030 Why?
Lipid Metabolism1202219010.030 Why?
Heterozygote2201127910.030 Why?
Protein Binding1200593430.030 Why?
Exons1201923920.030 Why?
Metabolic Networks and Pathways120187980.030 Why?
Cell Growth Processes120143810.030 Why?
Administration, Oral1202140390.030 Why?
Metabolomics1202216740.030 Why?
Melanoma, Experimental120165590.030 Why?
Valine120144100.030 Why?
Adenosine Triphosphatases120168410.030 Why?
Gene Duplication120133150.030 Why?
Neoplasm Invasiveness1202036330.030 Why?
Nanostructures120175530.020 Why?
Cell Membrane1202136630.020 Why?
Testosterone1202324930.020 Why?
Organ Specificity1201619670.020 Why?
Lymphocytes, Tumor-Infiltrating1201811050.020 Why?
Phenylthiohydantoin120132080.020 Why?
Genotype22018130420.020 Why?
Transfection1201957640.020 Why?
Loss of Heterozygosity120136630.020 Why?
Endothelial Cells1202435870.020 Why?
Orchiectomy120134660.020 Why?
Adaptor Proteins, Signal Transducing1202129110.020 Why?
Amino Acids1201617160.020 Why?
BRCA1 Protein1201711550.020 Why?
Kaplan-Meier Estimate1202165410.020 Why?
Cell Line12004155970.020 Why?
Genes, myc120113910.020 Why?
Fatty Acids1201818150.020 Why?
Alleles2201368920.020 Why?
Zebrafish Proteins1201610190.020 Why?
Single-Cell Analysis1202125330.020 Why?
Mammary Neoplasms, Animal120101220.020 Why?
Female820243970890.020 Why?
Gene Knockdown Techniques1201316080.020 Why?
Pheochromocytoma120113280.020 Why?
Up-Regulation1201841420.020 Why?
Mice, Inbred CBA120094380.020 Why?
Proto-Oncogene Proteins1202145260.020 Why?
Cell Movement1202052150.020 Why?
Survival Analysis12021101170.020 Why?
Glutamic Acid1201411930.020 Why?
Mesenchymal Stem Cells1201916710.020 Why?
Energy Metabolism1201929060.020 Why?
Mammals1201311360.020 Why?
Nitriles120139840.020 Why?
Cells, Cultured22013190220.020 Why?
Cell Line, Transformed120098670.020 Why?
Glucose1201943520.020 Why?
Adenovirus E1A Proteins12007810.020 Why?
Benzamides1201313800.020 Why?
Treatment Outcome12013653790.020 Why?
Treatment Failure1201326630.020 Why?
Neoplasm Transplantation1201020170.020 Why?
Genes, Tumor Suppressor1201010640.020 Why?
Gene Dosage1201012210.020 Why?
Homozygote1201017790.020 Why?
Immunity, Innate1201730780.010 Why?
Zebrafish1201630370.010 Why?
B-Lymphocytes1201847850.010 Why?
Embryo, Mammalian1201016740.010 Why?
Adenocarcinoma1202164060.010 Why?
Cell Separation1200917260.010 Why?
Gene Deletion1201126730.010 Why?
Neoplastic Stem Cells1201113560.010 Why?
Macrophages1201857960.010 Why?
Protein Biosynthesis1201020940.010 Why?
Base Sequence12013124220.010 Why?
Transcription, Genetic1201675990.010 Why?
Amino Acid Sequence12013134230.010 Why?
Transplantation, Heterologous1201023940.010 Why?
Molecular Sequence Data12013176260.010 Why?
Lung12019100890.010 Why?
T-Lymphocytes12018102670.010 Why?
Models, Genetic1201034420.010 Why?
DNA Damage1201024580.010 Why?
Prognosis12020300220.010 Why?
Lymphoma, B-Cell120069450.010 Why?
Fibroblasts1201041770.010 Why?
Flow Cytometry1200959000.010 Why?
Promoter Regions, Genetic1200958010.010 Why?
Myelodysplastic Syndromes1200813990.010 Why?
Middle Aged220232234910.010 Why?
Neoplasm Recurrence, Local1201494330.010 Why?
Cell Differentiation12013116680.010 Why?
Aged, 80 and over12020596860.010 Why?
Colonic Neoplasms1200625440.010 Why?
Immunohistochemistry12006111200.010 Why?
Genetic Predisposition to Disease12010180480.000 Why?
Aged120201715620.000 Why?
Adult120202236400.000 Why?
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Concepts (338)
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.