Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

John Gerard Clohessy, Ph.D.

Concepts (338)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
PTEN Phosphohydrolase14202011150.820 Why?
Drug Evaluation, Preclinical3201513470.410 Why?
Tumor Suppressor Protein p538201829240.360 Why?
TOR Serine-Threonine Kinases4201620580.340 Why?
Neoplasm Proteins4202136120.320 Why?
Leukemia, Promyelocytic, Acute220212510.310 Why?
Prostatic Neoplasms112020113450.310 Why?
Drug Resistance, Neoplasm7202152510.300 Why?
Proto-Oncogene Proteins c-akt7202424480.290 Why?
Tumor Suppressor Proteins4201928020.290 Why?
Xenograft Model Antitumor Assays8202435830.290 Why?
Disease Models, Animal112020181370.290 Why?
Mice412024812090.270 Why?
Anilides220204090.260 Why?
BH3 Interacting Domain Death Agonist Protein12005880.260 Why?
Antineoplastic Agents72024136270.260 Why?
Carcinoma, Non-Small-Cell Lung6202452510.250 Why?
Cytochromes c120051730.250 Why?
Ribosomal Protein S6 Kinases, 70-kDa220181010.240 Why?
Cell Line, Tumor212024169320.230 Why?
Pericytes220182930.220 Why?
RNA, Ribosomal220192260.220 Why?
Animals4720241679600.220 Why?
Indoles3201918290.210 Why?
Pantothenic Acid12022200.210 Why?
Nuclear Proteins6201957950.210 Why?
Coenzyme A12022400.200 Why?
Neoplasm Metastasis4201849020.200 Why?
Proto-Oncogene Proteins c-bcl-22200514080.200 Why?
Gene Expression Regulation, Neoplastic13202185120.200 Why?
Phosphatidylinositol 3-Kinase120221260.190 Why?
Computational Biology1201335050.190 Why?
Nipples120232210.190 Why?
Caspases120048780.190 Why?
Clinical Trials as Topic2201580550.190 Why?
Ubiquitin-Protein Ligases2202118880.180 Why?
Androgen Receptor Antagonists120211230.180 Why?
Sesquiterpenes120211760.170 Why?
Lipogenesis220202100.170 Why?
Glucose Transporter Type 312019160.170 Why?
Lung Neoplasms62024132620.170 Why?
Phosphatidylinositol 3-Kinases4202128640.170 Why?
Trans-Activators1200928600.160 Why?
Quinolines120247590.160 Why?
Dyskeratosis Congenita12019730.160 Why?
Mammary Neoplasms, Experimental120215070.160 Why?
Mutation102021299570.160 Why?
Thyroid Neoplasms3201823320.150 Why?
Sterol Regulatory Element Binding Proteins12018250.150 Why?
Cytoplasm3201315160.150 Why?
Databases, Factual1201380220.150 Why?
Organoids220217290.150 Why?
Caveolin 1120192570.150 Why?
Protein Phosphatase 1120181340.140 Why?
Anticarcinogenic Agents120192490.140 Why?
Lipoylation12018880.140 Why?
Cell Proliferation102024104420.140 Why?
Pyridines2202028790.140 Why?
Growth and Development12016470.140 Why?
Signal Transduction142022233740.140 Why?
Molecular Targeted Therapy4202128030.140 Why?
Leukemia, Myeloid, Acute5201936100.140 Why?
RNA Processing, Post-Transcriptional120194150.140 Why?
Apoptosis5202194970.140 Why?
Positive Transcriptional Elongation Factor B12016420.130 Why?
DNA, Intergenic120161050.130 Why?
Proto-Oncogene Proteins B-raf2201820530.130 Why?
Cell Cycle Proteins2202434480.130 Why?
Neoplasms52019220750.130 Why?
Mice, Transgenic10202195300.130 Why?
Tretinoin120195190.130 Why?
Proteomics2202438170.130 Why?
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors120183170.130 Why?
RNA-Binding Proteins2201618940.130 Why?
Benzimidazoles120218580.130 Why?
HMGB1 Protein120171370.130 Why?
Fertility120207730.130 Why?
Genetic Pleiotropy120161810.130 Why?
Cholesterol1202429240.120 Why?
Pyrazines1202111990.120 Why?
RNA, Messenger52019127620.120 Why?
Animal Husbandry12015640.120 Why?
Chemokine CXCL12120174540.120 Why?
Receptors, Androgen1202110770.120 Why?
Transcription Factors52021121020.120 Why?
Transforming Growth Factor beta1120186080.120 Why?
Hematopoiesis1200420630.120 Why?
Phthalazines120173820.120 Why?
Elafin12014310.120 Why?
Mice, SCID4202126270.120 Why?
Cell Transformation, Neoplastic5201828290.120 Why?
Multiprotein Complexes3201611200.120 Why?
Hemangiopericytoma12014710.120 Why?
Hematopoietic Stem Cells2201933900.110 Why?
Epigenomics120199360.110 Why?
Phosphotransferases (Alcohol Group Acceptor)220224360.110 Why?
Proto-Oncogene Proteins c-myc120199950.110 Why?
Protein Kinase Inhibitors4202056400.110 Why?
RNA2202127230.110 Why?
Public Sector120152650.110 Why?
Mice, Knockout82021143740.110 Why?
Genes, Neoplasm120153700.110 Why?
Receptor Protein-Tyrosine Kinases1202016130.110 Why?
Pancreatic Neoplasms2202153490.110 Why?
Proto-Oncogene Proteins p21(ras)1202117280.110 Why?
Phosphoric Monoester Hydrolases120154130.110 Why?
Drug Repositioning120152320.110 Why?
Isocitrate Dehydrogenase120199290.110 Why?
Carcinoma, Pancreatic Ductal2202117220.100 Why?
NF-kappa B1202124860.100 Why?
Therapies, Investigational120131120.100 Why?
Gallbladder Neoplasms120141900.100 Why?
Poly(ADP-ribose) Polymerases120144280.100 Why?
Eukaryotic Initiation Factors12012870.100 Why?
Private Sector120153970.100 Why?
Enzyme Activation1201836020.100 Why?
Muscles1201615810.100 Why?
Adenocarcinoma, Follicular120153250.100 Why?
Humans5020247606130.100 Why?
Naphthyridines120121410.090 Why?
Germ-Line Mutation1201918420.090 Why?
DNA-Binding Proteins2201995910.090 Why?
Epithelial Cells2202136630.090 Why?
MAP Kinase Signaling System1201814830.090 Why?
Histones1202125820.090 Why?
Neutrophils2202037670.090 Why?
Ribosomes120135010.090 Why?
fms-Like Tyrosine Kinase 3120134960.090 Why?
Lysosomes320219200.090 Why?
Myeloid Cells220188210.090 Why?
Breast Neoplasms42023210290.080 Why?
Hydroxymethylglutaryl-CoA Reductase Inhibitors1202433320.080 Why?
Chromatin1202129380.080 Why?
Nanoparticles1202019430.080 Why?
Oncogene Proteins220167190.080 Why?
HEK293 Cells4201942630.080 Why?
Drug Synergism2202417520.080 Why?
Interprofessional Relations120159890.080 Why?
Purines120126050.080 Why?
Oncogenes2202112200.080 Why?
Immunotherapy2202146420.080 Why?
Sarcoma1201917860.080 Why?
Medical Informatics120157330.070 Why?
Drug Approval120158160.070 Why?
Regeneration1201615060.070 Why?
Gene Expression Regulation32021119020.070 Why?
Tumor Microenvironment4202438440.070 Why?
Drug Discovery1201510570.070 Why?
DNA1202172330.070 Why?
Piperazines1201725250.070 Why?
Gene Expression Regulation, Enzymologic1201111730.070 Why?
Embryonic Stem Cells1201312620.070 Why?
Mass Spectrometry3202221920.070 Why?
Gene Expression Regulation, Leukemic120096450.060 Why?
bcl-2 Homologous Antagonist-Killer Protein12005710.060 Why?
Reverse Transcriptase Polymerase Chain Reaction3201345710.060 Why?
Androgens1201312910.060 Why?
Open Reading Frames220208140.060 Why?
Gene Expression Profiling5202194060.060 Why?
Models, Biological6201894680.060 Why?
Genome, Human1201844180.060 Why?
Down-Regulation1201229130.060 Why?
Two-Hybrid System Techniques120054580.060 Why?
TNF-Related Apoptosis-Inducing Ligand120051920.060 Why?
Mice, Nude2202136070.060 Why?
Peptides1201643540.060 Why?
bcl-2-Associated X Protein120052820.060 Why?
Sterol Regulatory Element Binding Protein 212024560.060 Why?
Sulfonamides1201419770.060 Why?
Mice, Inbred C57BL62019220200.060 Why?
Gene Knockout Techniques220198020.060 Why?
Angiogenesis Inhibitors1201420490.060 Why?
Androgen Antagonists1201314420.060 Why?
Cyclin-Dependent Kinase Inhibitor p16120076980.060 Why?
Ubiquitination2201910080.060 Why?
Pyrimidines1201630160.060 Why?
RNA, Neoplasm120067480.060 Why?
Proteome1201318550.050 Why?
Male2120213597180.050 Why?
Mice, Inbred NOD2202118370.050 Why?
Keratin-712023550.050 Why?
Endosomes220165190.050 Why?
Mitosis2202411910.050 Why?
Proteins3201860290.050 Why?
Jurkat Cells120047360.050 Why?
Mutagenesis, Site-Directed1200516930.050 Why?
Acetyl Coenzyme A12022750.050 Why?
Protein Stability120245660.050 Why?
Tumor Cells, Cultured2202061300.050 Why?
Phosphorylation2202483110.050 Why?
Equilibrative Nucleoside Transporter 112021170.050 Why?
Telomerase120067470.050 Why?
Transforming Growth Factor beta1200919590.050 Why?
Gene Amplification2201810850.050 Why?
Blotting, Western2200950390.050 Why?
Gene Silencing3201815120.050 Why?
RNA, Small Interfering2202134420.050 Why?
Gene Regulatory Networks2202117410.050 Why?
Diagnostic Imaging1201535270.050 Why?
Cell Cycle2202429350.050 Why?
Ki-67 Antigen120236310.050 Why?
Gene Expression1201375870.040 Why?
Mice, Inbred ICR120213640.040 Why?
Apoptosis Regulatory Proteins1200511350.040 Why?
RNA, Small Nucleolar12019260.040 Why?
Hyperplasia1202311550.040 Why?
HeLa Cells1200531050.040 Why?
Spermatogenesis120202570.040 Why?
U937 Cells120192620.040 Why?
Leukemia1200715230.040 Why?
Amino Acid Motifs120219290.040 Why?
Protein Structure, Tertiary1200538000.040 Why?
Proto-Oncogenes120193200.040 Why?
Antineoplastic Combined Chemotherapy Protocols12019117130.040 Why?
COS Cells1202011290.040 Why?
Cysteine120228950.040 Why?
HL-60 Cells120183630.040 Why?
Melanoma1201656970.040 Why?
RNA Interference1200528460.040 Why?
Endocytosis120219590.040 Why?
Deoxycytidine120218720.030 Why?
Methylation1201910810.030 Why?
Cell Communication1202416530.030 Why?
K562 Cells120186400.030 Why?
Protein Isoforms1202116970.030 Why?
Cytarabine120186960.030 Why?
Microfilament Proteins1202111350.030 Why?
RNA Splicing120219150.030 Why?
Adenosine Triphosphate1202219930.030 Why?
Benzylamines120172480.030 Why?
Hematologic Neoplasms1200819010.030 Why?
Heterocyclic Compounds120172470.030 Why?
Carrier Proteins1200949380.030 Why?
Tumor Burden1202118950.030 Why?
High-Throughput Screening Assays120219440.030 Why?
Membrane Glycoproteins1200537090.030 Why?
Radiation Tolerance120174800.030 Why?
Tumor Necrosis Factor-alpha1200543560.030 Why?
Genetic Heterogeneity120187240.030 Why?
Alternative Splicing1201910910.030 Why?
Microtubules1202010720.030 Why?
Polysaccharides1202010160.030 Why?
Protein Multimerization120199830.030 Why?
Pharmacogenetics120186800.030 Why?
Neoplasms, Experimental1201912290.030 Why?
Lipid Metabolism1202219020.030 Why?
Heterozygote2201127980.030 Why?
Protein Binding1200593350.030 Why?
Metabolic Networks and Pathways120187880.030 Why?
Cell Growth Processes120143840.030 Why?
Exons1201923890.030 Why?
Metabolomics1202216280.030 Why?
Administration, Oral1202140350.030 Why?
Melanoma, Experimental120165620.030 Why?
Valine120144090.030 Why?
Neoplasm Invasiveness1202036180.030 Why?
Gene Duplication120133140.030 Why?
Adenosine Triphosphatases120168330.030 Why?
Nanostructures120175470.030 Why?
Organ Specificity1201619540.020 Why?
Testosterone1202324700.020 Why?
Lymphocytes, Tumor-Infiltrating1201810880.020 Why?
Cell Membrane1202136820.020 Why?
Phenylthiohydantoin120132040.020 Why?
Genotype22018129570.020 Why?
Loss of Heterozygosity120136590.020 Why?
Transfection1201957810.020 Why?
Endothelial Cells1202435390.020 Why?
Orchiectomy120134700.020 Why?
Adaptor Proteins, Signal Transducing1202128960.020 Why?
Amino Acids1201617140.020 Why?
BRCA1 Protein1201711470.020 Why?
Kaplan-Meier Estimate1202165440.020 Why?
Cell Line12004156200.020 Why?
Genes, myc120113950.020 Why?
Fatty Acids1201818040.020 Why?
Single-Cell Analysis1202123800.020 Why?
Alleles2201369000.020 Why?
Zebrafish Proteins1201610060.020 Why?
Female820243912460.020 Why?
Mammary Neoplasms, Animal120101240.020 Why?
Up-Regulation1201841220.020 Why?
Pheochromocytoma120113280.020 Why?
Mice, Inbred CBA120094360.020 Why?
Gene Knockdown Techniques1201316170.020 Why?
Glutamic Acid1201411670.020 Why?
Proto-Oncogene Proteins1202144960.020 Why?
Cell Movement1202052060.020 Why?
Survival Analysis12021101850.020 Why?
Mesenchymal Stem Cells1201916340.020 Why?
Energy Metabolism1201928690.020 Why?
Nitriles120139560.020 Why?
Mammals1201311310.020 Why?
Cells, Cultured22013189550.020 Why?
Cell Line, Transformed120098690.020 Why?
Adenovirus E1A Proteins12007730.020 Why?
Benzamides1201313690.020 Why?
Glucose1201943500.020 Why?
Treatment Failure1201326470.020 Why?
Treatment Outcome12013649810.020 Why?
Neoplasm Transplantation1201020140.020 Why?
Genes, Tumor Suppressor1201010550.020 Why?
Gene Dosage1201012180.020 Why?
Homozygote1201017880.020 Why?
Immunity, Innate1201730470.010 Why?
Zebrafish1201629970.010 Why?
B-Lymphocytes1201847420.010 Why?
Embryo, Mammalian1201016740.010 Why?
Adenocarcinoma1202163160.010 Why?
Cell Separation1200917200.010 Why?
Gene Deletion1201126680.010 Why?
Neoplastic Stem Cells1201113470.010 Why?
Macrophages1201857450.010 Why?
Protein Biosynthesis1201021040.010 Why?
Base Sequence12013124440.010 Why?
Transcription, Genetic1201675930.010 Why?
Amino Acid Sequence12013134510.010 Why?
Transplantation, Heterologous1201023790.010 Why?
Lung1201999940.010 Why?
Molecular Sequence Data12013176240.010 Why?
T-Lymphocytes12018101810.010 Why?
DNA Damage1201024420.010 Why?
Models, Genetic1201034420.010 Why?
Prognosis12020296610.010 Why?
Lymphoma, B-Cell120069350.010 Why?
Fibroblasts1201040890.010 Why?
Flow Cytometry1200958690.010 Why?
Promoter Regions, Genetic1200957820.010 Why?
Myelodysplastic Syndromes1200814010.010 Why?
Middle Aged220232203590.010 Why?
Neoplasm Recurrence, Local1201492780.010 Why?
Cell Differentiation12013114810.010 Why?
Aged, 80 and over12020589800.010 Why?
Colonic Neoplasms1200625260.010 Why?
Immunohistochemistry12006110700.010 Why?
Genetic Predisposition to Disease12010177900.000 Why?
Aged120201691430.000 Why?
Adult120202200070.000 Why?
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Concepts (338)
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.