Harvard Catalyst Profiles

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John Gerard Clohessy, Ph.D.

Concepts (338)

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Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
PTEN Phosphohydrolase14202011170.800 Why?
Drug Evaluation, Preclinical3201513310.410 Why?
Tumor Suppressor Protein p538201829450.350 Why?
TOR Serine-Threonine Kinases4201620560.340 Why?
Neoplasm Proteins4202135940.320 Why?
Prostatic Neoplasms112020110920.310 Why?
Leukemia, Promyelocytic, Acute220212490.300 Why?
Drug Resistance, Neoplasm7202153340.300 Why?
Tumor Suppressor Proteins4201927930.290 Why?
Proto-Oncogene Proteins c-akt7202424540.280 Why?
Xenograft Model Antitumor Assays8202436050.280 Why?
Disease Models, Animal112020183140.280 Why?
Mice412024818210.260 Why?
Anilides220204130.260 Why?
Antineoplastic Agents72024136340.250 Why?
BH3 Interacting Domain Death Agonist Protein12005880.250 Why?
Carcinoma, Non-Small-Cell Lung6202453880.250 Why?
Cytochromes c120051730.240 Why?
Ribosomal Protein S6 Kinases, 70-kDa220181010.240 Why?
Cell Line, Tumor212024170700.230 Why?
Pericytes220182990.220 Why?
RNA, Ribosomal220192270.220 Why?
Animals4720241687750.210 Why?
Indoles3201918320.210 Why?
Pantothenic Acid12022170.200 Why?
Nuclear Proteins6201957910.200 Why?
Coenzyme A12022390.200 Why?
Neoplasm Metastasis4201848860.200 Why?
Proto-Oncogene Proteins c-bcl-22200514060.190 Why?
Gene Expression Regulation, Neoplastic13202186130.190 Why?
Phosphatidylinositol 3-Kinase120221250.190 Why?
Computational Biology1201335630.190 Why?
Clinical Trials as Topic2201580370.180 Why?
Caspases120048810.180 Why?
Nipples120232220.180 Why?
Ubiquitin-Protein Ligases2202118970.180 Why?
Androgen Receptor Antagonists120211230.170 Why?
Sesquiterpenes120211750.170 Why?
Lipogenesis220202170.170 Why?
Glucose Transporter Type 312019160.170 Why?
Phosphatidylinositol 3-Kinases4202128780.160 Why?
Lung Neoplasms62024134820.160 Why?
Trans-Activators1200928490.160 Why?
Dyskeratosis Congenita12019700.160 Why?
Quinolines120247690.160 Why?
Mammary Neoplasms, Experimental120214960.160 Why?
Mutation102021302080.160 Why?
Thyroid Neoplasms3201823550.150 Why?
Cytoplasm3201314980.150 Why?
Sterol Regulatory Element Binding Proteins12018250.150 Why?
Databases, Factual1201380620.150 Why?
Organoids220217410.140 Why?
Caveolin 1120192550.140 Why?
Anticarcinogenic Agents120192500.140 Why?
Protein Phosphatase 1120181350.140 Why?
Lipoylation12018870.140 Why?
Cell Proliferation102024104310.140 Why?
Pyridines2202028890.140 Why?
RNA Processing, Post-Transcriptional120193920.140 Why?
Growth and Development12016460.140 Why?
Molecular Targeted Therapy4202128250.140 Why?
Signal Transduction142022236000.140 Why?
Leukemia, Myeloid, Acute5201936360.130 Why?
Apoptosis5202195070.130 Why?
Cell Cycle Proteins2202434360.130 Why?
Proto-Oncogene Proteins B-raf2201820540.130 Why?
Positive Transcriptional Elongation Factor B12016420.130 Why?
Neoplasms52019223360.130 Why?
DNA, Intergenic120161080.130 Why?
Mice, Transgenic10202195360.130 Why?
Tretinoin120195240.130 Why?
Proteomics2202439070.130 Why?
RNA-Binding Proteins2201618830.130 Why?
Benzimidazoles120218620.130 Why?
Fertility120207700.130 Why?
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors120183230.130 Why?
HMGB1 Protein120171390.120 Why?
Cholesterol1202429010.120 Why?
Genetic Pleiotropy120161820.120 Why?
Pyrazines1202112040.120 Why?
RNA, Messenger52019127720.120 Why?
Animal Husbandry12015640.120 Why?
Chemokine CXCL12120174550.120 Why?
Transcription Factors52021121280.120 Why?
Hematopoiesis1200420600.120 Why?
Receptors, Androgen1202110880.120 Why?
Transforming Growth Factor beta1120186370.120 Why?
Mice, SCID4202126250.120 Why?
Elafin12014290.120 Why?
Phthalazines120173970.120 Why?
Cell Transformation, Neoplastic5201828380.110 Why?
Multiprotein Complexes3201611070.110 Why?
Hemangiopericytoma12014710.110 Why?
Hematopoietic Stem Cells2201934050.110 Why?
Epigenomics120199590.110 Why?
Proto-Oncogene Proteins c-myc120199970.110 Why?
Phosphotransferases (Alcohol Group Acceptor)220224330.110 Why?
RNA2202127150.110 Why?
Protein Kinase Inhibitors4202056950.110 Why?
Public Sector120152650.110 Why?
Mice, Knockout82021144550.110 Why?
Genes, Neoplasm120153690.110 Why?
Receptor Protein-Tyrosine Kinases1202016210.110 Why?
Pancreatic Neoplasms2202154540.110 Why?
Phosphoric Monoester Hydrolases120154150.100 Why?
Proto-Oncogene Proteins p21(ras)1202117650.100 Why?
Drug Repositioning120152450.100 Why?
Isocitrate Dehydrogenase120199550.100 Why?
Carcinoma, Pancreatic Ductal2202117620.100 Why?
NF-kappa B1202124950.100 Why?
Therapies, Investigational120131100.100 Why?
Poly(ADP-ribose) Polymerases120144280.100 Why?
Gallbladder Neoplasms120141900.100 Why?
Eukaryotic Initiation Factors12012830.100 Why?
Muscles1201615760.100 Why?
Enzyme Activation1201835840.100 Why?
Private Sector120153960.100 Why?
Adenocarcinoma, Follicular120153230.090 Why?
Humans5020247660000.090 Why?
DNA-Binding Proteins2201996000.090 Why?
Epithelial Cells2202136840.090 Why?
Germ-Line Mutation1201918850.090 Why?
MAP Kinase Signaling System1201814900.090 Why?
Neutrophils2202037700.090 Why?
Histones1202125910.090 Why?
Naphthyridines120121840.090 Why?
Ribosomes120134950.090 Why?
fms-Like Tyrosine Kinase 3120134960.080 Why?
Myeloid Cells220188380.080 Why?
Lysosomes320219320.080 Why?
Hydroxymethylglutaryl-CoA Reductase Inhibitors1202432490.080 Why?
Breast Neoplasms42023210720.080 Why?
Oncogene Proteins220167110.080 Why?
Chromatin1202129800.080 Why?
HEK293 Cells4201942620.080 Why?
Nanoparticles1202019650.080 Why?
Interprofessional Relations120159980.080 Why?
Drug Synergism2202417530.080 Why?
Oncogenes2202112310.080 Why?
Purines120126160.080 Why?
Sarcoma1201918010.070 Why?
Immunotherapy2202147460.070 Why?
Drug Approval120158200.070 Why?
Medical Informatics120157430.070 Why?
Regeneration1201615160.070 Why?
Gene Expression Regulation32021119060.070 Why?
DNA1202171920.070 Why?
Tumor Microenvironment4202439420.070 Why?
Drug Discovery1201510650.070 Why?
Piperazines1201725470.070 Why?
Gene Expression Regulation, Enzymologic1201111670.070 Why?
Embryonic Stem Cells1201312420.070 Why?
Mass Spectrometry3202221970.060 Why?
Gene Expression Regulation, Leukemic120096570.060 Why?
Reverse Transcriptase Polymerase Chain Reaction3201345650.060 Why?
bcl-2 Homologous Antagonist-Killer Protein12005700.060 Why?
Androgens1201312780.060 Why?
Open Reading Frames220208180.060 Why?
Models, Biological6201894460.060 Why?
Gene Expression Profiling5202195240.060 Why?
Genome, Human1201844420.060 Why?
Down-Regulation1201229270.060 Why?
Two-Hybrid System Techniques120054630.060 Why?
Mice, Nude2202136100.060 Why?
Peptides1201643380.060 Why?
TNF-Related Apoptosis-Inducing Ligand120051950.060 Why?
bcl-2-Associated X Protein120052820.060 Why?
Sulfonamides1201419800.060 Why?
Sterol Regulatory Element Binding Protein 212024580.060 Why?
Androgen Antagonists1201314110.060 Why?
Angiogenesis Inhibitors1201420460.060 Why?
Gene Knockout Techniques220198000.060 Why?
Mice, Inbred C57BL62019223340.060 Why?
Cyclin-Dependent Kinase Inhibitor p16120077020.060 Why?
Ubiquitination2201910000.060 Why?
Pyrimidines1201630480.050 Why?
RNA, Neoplasm120067440.050 Why?
Proteome1201318950.050 Why?
Mice, Inbred NOD2202118360.050 Why?
Male2120213638550.050 Why?
Keratin-712023550.050 Why?
Mitosis2202411750.050 Why?
Proteins3201859940.050 Why?
Endosomes220165210.050 Why?
Jurkat Cells120047380.050 Why?
Mutagenesis, Site-Directed1200516770.050 Why?
Acetyl Coenzyme A12022740.050 Why?
Tumor Cells, Cultured2202061010.050 Why?
Protein Stability120245760.050 Why?
Phosphorylation2202482900.050 Why?
Equilibrative Nucleoside Transporter 112021170.050 Why?
Telomerase120067490.050 Why?
Gene Amplification2201810880.050 Why?
Transforming Growth Factor beta1200919960.050 Why?
Blotting, Western2200950190.050 Why?
Gene Silencing3201815050.050 Why?
Diagnostic Imaging1201535290.050 Why?
Gene Regulatory Networks2202117490.050 Why?
RNA, Small Interfering2202134230.040 Why?
Cell Cycle2202429210.040 Why?
Gene Expression1201375810.040 Why?
Ki-67 Antigen120236280.040 Why?
Mice, Inbred ICR120213610.040 Why?
Apoptosis Regulatory Proteins1200511500.040 Why?
RNA, Small Nucleolar12019270.040 Why?
Hyperplasia1202311420.040 Why?
HeLa Cells1200530700.040 Why?
Spermatogenesis120202590.040 Why?
Amino Acid Motifs120219240.040 Why?
Leukemia1200715210.040 Why?
U937 Cells120192590.040 Why?
Protein Structure, Tertiary1200537500.040 Why?
Proto-Oncogenes120193200.040 Why?
Antineoplastic Combined Chemotherapy Protocols12019118580.040 Why?
COS Cells1202011350.040 Why?
Cysteine120228980.040 Why?
HL-60 Cells120183640.040 Why?
Melanoma1201656950.040 Why?
RNA Interference1200528250.030 Why?
Endocytosis120219520.030 Why?
Deoxycytidine120218860.030 Why?
Cell Communication1202416600.030 Why?
Methylation1201910740.030 Why?
K562 Cells120186440.030 Why?
Protein Isoforms1202117150.030 Why?
RNA Splicing120219020.030 Why?
Microfilament Proteins1202111300.030 Why?
Cytarabine120186960.030 Why?
Adenosine Triphosphate1202220010.030 Why?
Benzylamines120172510.030 Why?
Hematologic Neoplasms1200819260.030 Why?
Heterocyclic Compounds120172450.030 Why?
Carrier Proteins1200949100.030 Why?
High-Throughput Screening Assays120219380.030 Why?
Tumor Burden1202118890.030 Why?
Membrane Glycoproteins1200536920.030 Why?
Radiation Tolerance120174750.030 Why?
Tumor Necrosis Factor-alpha1200543420.030 Why?
Genetic Heterogeneity120187350.030 Why?
Microtubules1202010620.030 Why?
Protein Multimerization120199590.030 Why?
Alternative Splicing1201911020.030 Why?
Polysaccharides1202010170.030 Why?
Neoplasms, Experimental1201912270.030 Why?
Pharmacogenetics120186820.030 Why?
Lipid Metabolism1202218950.030 Why?
Heterozygote2201127960.030 Why?
Protein Binding1200593020.030 Why?
Exons1201923920.030 Why?
Cell Growth Processes120143800.030 Why?
Metabolic Networks and Pathways120187990.030 Why?
Administration, Oral1202140160.030 Why?
Metabolomics1202216740.030 Why?
Melanoma, Experimental120165550.030 Why?
Valine120144100.030 Why?
Adenosine Triphosphatases120168390.030 Why?
Neoplasm Invasiveness1202036040.030 Why?
Gene Duplication120133160.030 Why?
Nanostructures120175490.020 Why?
Cell Membrane1202136350.020 Why?
Testosterone1202324950.020 Why?
Organ Specificity1201619660.020 Why?
Lymphocytes, Tumor-Infiltrating1201811050.020 Why?
Genotype22018130290.020 Why?
Phenylthiohydantoin120132060.020 Why?
Transfection1201957390.020 Why?
Loss of Heterozygosity120136630.020 Why?
Endothelial Cells1202435860.020 Why?
Orchiectomy120134650.020 Why?
Adaptor Proteins, Signal Transducing1202128980.020 Why?
Amino Acids1201617110.020 Why?
BRCA1 Protein1201711550.020 Why?
Kaplan-Meier Estimate1202165060.020 Why?
Cell Line12004155450.020 Why?
Genes, myc120113910.020 Why?
Fatty Acids1201818060.020 Why?
Alleles2201368920.020 Why?
Zebrafish Proteins1201610170.020 Why?
Single-Cell Analysis1202125350.020 Why?
Female820243961580.020 Why?
Mammary Neoplasms, Animal120101220.020 Why?
Pheochromocytoma120113260.020 Why?
Gene Knockdown Techniques1201316030.020 Why?
Up-Regulation1201841330.020 Why?
Mice, Inbred CBA120094390.020 Why?
Cell Movement1202051940.020 Why?
Survival Analysis12021100890.020 Why?
Proto-Oncogene Proteins1202145200.020 Why?
Glutamic Acid1201411810.020 Why?
Mesenchymal Stem Cells1201916630.020 Why?
Energy Metabolism1201928970.020 Why?
Mammals1201311250.020 Why?
Nitriles120139810.020 Why?
Cells, Cultured22013189640.020 Why?
Cell Line, Transformed120098580.020 Why?
Glucose1201943350.020 Why?
Benzamides1201313760.020 Why?
Adenovirus E1A Proteins12007810.020 Why?
Treatment Outcome12013651990.020 Why?
Treatment Failure1201326530.020 Why?
Neoplasm Transplantation1201020100.020 Why?
Genes, Tumor Suppressor1201010580.020 Why?
Gene Dosage1201012110.020 Why?
Homozygote1201017750.020 Why?
Immunity, Innate1201730770.010 Why?
Zebrafish1201630350.010 Why?
B-Lymphocytes1201847830.010 Why?
Embryo, Mammalian1201016740.010 Why?
Cell Separation1200917180.010 Why?
Adenocarcinoma1202163610.010 Why?
Gene Deletion1201126670.010 Why?
Neoplastic Stem Cells1201113510.010 Why?
Macrophages1201857750.010 Why?
Protein Biosynthesis1201020910.010 Why?
Base Sequence12013124050.010 Why?
Transcription, Genetic1201675990.010 Why?
Amino Acid Sequence12013134000.010 Why?
Transplantation, Heterologous1201023900.010 Why?
Molecular Sequence Data12013175970.010 Why?
Lung12019100600.010 Why?
T-Lymphocytes12018102600.010 Why?
Models, Genetic1201034480.010 Why?
DNA Damage1201024640.010 Why?
Prognosis12020299040.010 Why?
Lymphoma, B-Cell120069430.010 Why?
Fibroblasts1201041610.010 Why?
Flow Cytometry1200958790.010 Why?
Promoter Regions, Genetic1200957840.010 Why?
Myelodysplastic Syndromes1200814040.010 Why?
Middle Aged220232230250.010 Why?
Neoplasm Recurrence, Local1201493780.010 Why?
Cell Differentiation12013116420.010 Why?
Aged, 80 and over12020594930.010 Why?
Colonic Neoplasms1200625320.010 Why?
Immunohistochemistry12006110350.010 Why?
Genetic Predisposition to Disease12010180760.000 Why?
Aged120201711610.000 Why?
Adult120202231060.000 Why?
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© 2025 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.