Nuclear Receptor Subfamily 1, Group F, Member 1
"Nuclear Receptor Subfamily 1, Group F, Member 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-binding orphan nuclear receptor that positively regulates expression of ARNTL TRANSCRIPTION FACTORS and is a regulatory component of the circadian clock system. The protein also has a role in neuron cell survival and differentiation in that loss of function mutations of its gene result in the mouse phenotype referred to as the STAGGERER MOUSE.
MeSH Number(s)
D12.776.189.437
D12.776.260.698.209.100
D12.776.826.209.100
D12.776.930.669.209.100
Concept/Terms
Nuclear Receptor Subfamily 1, Group F, Member 1- Nuclear Receptor Subfamily 1, Group F, Member 1
- Nuclear Receptor ROR-alpha
- Nuclear Receptor ROR alpha
- Retinoid-Related Orphan Receptor-alpha
- Retinoid Related Orphan Receptor alpha
- Nuclear Receptor NR1F1
- NR1F1, Nuclear Receptor
- Receptor NR1F1, Nuclear
- RAR-Related Orphan Receptor A
- RAR Related Orphan Receptor A
Retinoid-Related Orphan Receptor-alpha4- Retinoid-Related Orphan Receptor-alpha4
- Retinoid Related Orphan Receptor alpha4
- Nuclear Receptor RZR-alpha
- Nuclear Receptor RZR alpha
- RZR-alpha, Nuclear Receptor
Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Subfamily 1, Group F, Member 1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Circadian Rhythm Signaling Peptides and Proteins [D12.776.189]
- Nuclear Receptor Subfamily 1, Group F, Member 1 [D12.776.189.437]
- DNA-Binding Proteins [D12.776.260]
- Receptors, Cytoplasmic and Nuclear [D12.776.260.698]
- Orphan Nuclear Receptors [D12.776.260.698.209]
- Nuclear Receptor Subfamily 1, Group F, Member 1 [D12.776.260.698.209.100]
- Receptors, Cytoplasmic and Nuclear [D12.776.826]
- Orphan Nuclear Receptors [D12.776.826.209]
- Nuclear Receptor Subfamily 1, Group F, Member 1 [D12.776.826.209.100]
- Transcription Factors [D12.776.930]
- Receptors, Cytoplasmic and Nuclear [D12.776.930.669]
- Orphan Nuclear Receptors [D12.776.930.669.209]
- Nuclear Receptor Subfamily 1, Group F, Member 1 [D12.776.930.669.209.100]
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Subfamily 1, Group F, Member 1".
This graph shows the total number of publications written about "Nuclear Receptor Subfamily 1, Group F, Member 1" by people in Harvard Catalyst Profiles by year, and whether "Nuclear Receptor Subfamily 1, Group F, Member 1" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 3 | 1 | 4 |
| 2014 | 1 | 0 | 1 |
| 2015 | 5 | 1 | 6 |
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 2 | 0 | 2 |
| 2019 | 2 | 0 | 2 |
Below are the most recent publications written about "Nuclear Receptor Subfamily 1, Group F, Member 1" by people in Profiles.
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Loss of RAR-related orphan receptor alpha (RORa) selectively lowers docosahexaenoic acid in developing cerebellum. Prostaglandins Leukot Essent Fatty Acids. 2020 01; 152:102036.
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Melatonin stabilizes rupture-prone vulnerable plaques via regulating macrophage polarization in a nuclear circadian receptor RORa-dependent manner. J Pineal Res. 2019 Sep; 67(2):e12581.
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Circadian clock pathway genes associated with colorectal cancer risk and prognosis. Arch Toxicol. 2018 08; 92(8):2681-2689.
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Dual Molecular Effects of Dominant RORA Mutations Cause Two Variants of Syndromic Intellectual Disability with Either Autism or Cerebellar Ataxia. Am J Hum Genet. 2018 05 03; 102(5):744-759.
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RORa-expressing T regulatory cells restrain allergic skin inflammation. Sci Immunol. 2018 03 02; 3(21).
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Adropin: An endocrine link between the biological clock and cholesterol homeostasis. Mol Metab. 2018 02; 8:51-64.
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Topical ROR Inverse Agonists Suppress Inflammation in Mouse Models of Atopic Dermatitis and Acute Irritant Dermatitis. J Invest Dermatol. 2017 12; 137(12):2523-2531.
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RORa modulates semaphorin 3E transcription and neurovascular interaction in pathological retinal angiogenesis. FASEB J. 2017 10; 31(10):4492-4502.
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Variations in T cell transcription factor gene structure and expression associated with the two disease forms of sheep paratuberculosis. Vet Res. 2016 08 17; 47(1):83.
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Circadian factors BMAL1 and RORa control HIF-1a transcriptional activity in nucleus pulposus cells: implications in maintenance of intervertebral disc health. Oncotarget. 2016 Apr 26; 7(17):23056-71.