Receptors, Aryl Hydrocarbon
"Receptors, Aryl Hydrocarbon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected.
MeSH Number(s)
D12.776.260.698.209.715
D12.776.826.209.715
D12.776.930.662
D12.776.930.669.209.715
Concept/Terms
Receptors, Aryl Hydrocarbon- Receptors, Aryl Hydrocarbon
- Receptors, AH
- Aryl Hydrocarbon Receptors
- Dioxin Receptor
- Receptor, Dioxin
- Dioxin Receptors
- Receptors, Dioxin
- Polyaromatic Hydrocarbon Receptors
- Polyaromatic Hydrocarbon Receptor
- Receptor, Polyaromatic Hydrocarbon
- Receptors, Polyaromatic Hydrocarbon
- TCDD Receptor
- Receptor, TCDD
- Receptors, TCDD
- TCDD Receptors
- AH Receptor
- Receptor, AH
- AH Receptors
- Receptors, 2,3,7,8-Tetrachlorodibenzo-p-dioxin
- Aryl Hydrocarbon Receptor
- Receptor, Aryl Hydrocarbon
Below are MeSH descriptors whose meaning is more general than "Receptors, Aryl Hydrocarbon".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Aryl Hydrocarbon".
This graph shows the total number of publications written about "Receptors, Aryl Hydrocarbon" by people in Harvard Catalyst Profiles by year, and whether "Receptors, Aryl Hydrocarbon" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1999 | 2 | 1 | 3 |
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 3 | 1 | 4 |
| 2003 | 3 | 0 | 3 |
| 2004 | 4 | 1 | 5 |
| 2005 | 2 | 1 | 3 |
| 2006 | 1 | 2 | 3 |
| 2008 | 1 | 0 | 1 |
| 2009 | 1 | 2 | 3 |
| 2010 | 3 | 1 | 4 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 3 | 3 |
| 2013 | 6 | 1 | 7 |
| 2014 | 2 | 2 | 4 |
| 2015 | 6 | 2 | 8 |
| 2016 | 7 | 1 | 8 |
| 2017 | 6 | 3 | 9 |
| 2018 | 8 | 5 | 13 |
| 2019 | 5 | 1 | 6 |
| 2020 | 7 | 4 | 11 |
| 2021 | 9 | 0 | 9 |
| 2022 | 1 | 3 | 4 |
| 2023 | 2 | 0 | 2 |
| 2024 | 0 | 1 | 1 |
Below are the most recent publications written about "Receptors, Aryl Hydrocarbon" by people in Profiles.
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Association between altered tryptophan metabolism, plasma aryl hydrocarbon receptor agonists, and inflammatory Chagas disease. Front Immunol. 2023; 14:1267641.
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Silencing of aryl hydrocarbon receptor repressor restrains Th17 cell immunity in autoimmune hepatitis. J Autoimmun. 2024 Feb; 143:103162.
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Melatonin and Its Metabolites Can Serve as Agonists on the Aryl Hydrocarbon Receptor and Peroxisome Proliferator-Activated Receptor Gamma. Int J Mol Sci. 2023 Oct 23; 24(20).
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Modulation of the Aryl Hydrocarbon Receptor Signaling Pathway Impacts on Junín Virus Replication. Viruses. 2023 01 28; 15(2).
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Identification of environmental factors that promote intestinal inflammation. Nature. 2022 11; 611(7937):801-809.
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GSTM2 is a key molecular determinant of resistance to SG-ARIs. Oncogene. 2022 09; 41(40):4498-4511.
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Peripheral blood CD3+ T-cell gene expression biomarkers correlate with clinical frailty in patients with haematological malignancies. Br J Haematol. 2022 10; 199(1):100-105.
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AhR Activation Leads to Attenuation of Murine Autoimmune Hepatitis: Single-Cell RNA-Seq Analysis Reveals Unique Immune Cell Phenotypes and Gene Expression Changes in the Liver. Front Immunol. 2022; 13:899609.
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Molecular and structural basis of interactions of vitamin D3 hydroxyderivatives with aryl hydrocarbon receptor (AhR): An integrated experimental and computational study. Int J Biol Macromol. 2022 Jun 01; 209(Pt A):1111-1123.
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Targeting AhR as a Novel Therapeutic Modality against Inflammatory Diseases. Int J Mol Sci. 2021 Dec 28; 23(1).