Nuclear Receptor Subfamily 1, Group D, Member 1
"Nuclear Receptor Subfamily 1, Group D, Member 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-binding orphan nuclear receptor that negatively regulates expression of ARNTL TRANSCRIPTION FACTORS and plays a role as a regulatory component of the circadian clock system. The Nr1d1 nuclear receptor expression is cyclically-regulated by a feedback loop involving its positive regulation by CLOCK PROTEIN; BMAL1 PROTEIN heterodimers and its negative regulation by CRYPTOCHROME and PERIOD PROTEINS.
MeSH Number(s)
D12.776.189.300
D12.776.260.698.209.080
D12.776.826.209.080
D12.776.930.669.209.080
Concept/Terms
Nuclear Receptor Subfamily 1, Group D, Member 1- Nuclear Receptor Subfamily 1, Group D, Member 1
- Rev-erb-alpha Nuclear Receptors
- Nuclear Receptors, Rev-erb-alpha
- Rev erb alpha Nuclear Receptors
- V-erbA-Related Protein EAR-1
- V erbA Related Protein EAR 1
- Nuclear Receptor NR1D1
- NR1D1, Nuclear Receptor
- Receptor NR1D1, Nuclear
Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Subfamily 1, Group D, Member 1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Circadian Rhythm Signaling Peptides and Proteins [D12.776.189]
- Nuclear Receptor Subfamily 1, Group D, Member 1 [D12.776.189.300]
- DNA-Binding Proteins [D12.776.260]
- Receptors, Cytoplasmic and Nuclear [D12.776.260.698]
- Orphan Nuclear Receptors [D12.776.260.698.209]
- Nuclear Receptor Subfamily 1, Group D, Member 1 [D12.776.260.698.209.080]
- Receptors, Cytoplasmic and Nuclear [D12.776.826]
- Orphan Nuclear Receptors [D12.776.826.209]
- Nuclear Receptor Subfamily 1, Group D, Member 1 [D12.776.826.209.080]
- Transcription Factors [D12.776.930]
- Receptors, Cytoplasmic and Nuclear [D12.776.930.669]
- Orphan Nuclear Receptors [D12.776.930.669.209]
- Nuclear Receptor Subfamily 1, Group D, Member 1 [D12.776.930.669.209.080]
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Subfamily 1, Group D, Member 1".
This graph shows the total number of publications written about "Nuclear Receptor Subfamily 1, Group D, Member 1" by people in Harvard Catalyst Profiles by year, and whether "Nuclear Receptor Subfamily 1, Group D, Member 1" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 3 | 1 | 4 |
| 2020 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
| 2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Nuclear Receptor Subfamily 1, Group D, Member 1" by people in Profiles.
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The Role of REV-ERB Receptors in Cancer Pathogenesis. Int J Mol Sci. 2023 May 19; 24(10).
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Circadian Cadence and NR1D1 Tune Cardiovascular Disease. J Am Coll Cardiol. 2022 05 31; 79(21):2116-2118.
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REV-ERBa regulates age-related and oxidative stress-induced degeneration in retinal pigment epithelium via NRF2. Redox Biol. 2022 05; 51:102261.
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Single-cell in vivo imaging of cellular circadian oscillators in zebrafish. PLoS Biol. 2020 03; 18(3):e3000435.
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Circadian rhythm-dependent and circadian rhythm-independent impacts of the molecular clock on type 3 innate lymphoid cells. Sci Immunol. 2019 10 04; 4(40).
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SR9009 has REV-ERB-independent effects on cell proliferation and metabolism. Proc Natl Acad Sci U S A. 2019 06 18; 116(25):12147-12152.
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Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice. PLoS Genet. 2019 05; 15(5):e1008084.
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Circadian clock protein Rev-erba regulates neuroinflammation. Proc Natl Acad Sci U S A. 2019 03 12; 116(11):5102-5107.
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Rev-erba dynamically modulates chromatin looping to control circadian gene transcription. Science. 2018 03 16; 359(6381):1274-1277.
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Protein malnutrition after weaning disrupts peripheral clock and daily insulin secretion in mice. J Nutr Biochem. 2017 12; 50:54-65.