Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Darren E. Higgins, Ph.D.

Concepts (360)

Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Listeria monocytogenes4620212528.100 Why?
Listeriosis2020211503.320 Why?
Heat-Shock Proteins2220198081.810 Why?
Bacterial Toxins2020199411.710 Why?
Hemolysin Proteins2020191131.560 Why?
Flagella62011991.360 Why?
Bacterial Proteins19201838601.250 Why?
Vacuoles1020182291.120 Why?
Virulence15201913280.890 Why?
Gene Expression Regulation, Bacterial7201811240.820 Why?
Cytosol820139060.770 Why?
Macrophages19202057100.740 Why?
Host-Pathogen Interactions9202114830.690 Why?
Virulence Factors320215120.680 Why?
Type C Phospholipases620142920.650 Why?
Nisin1201840.640 Why?
Vimentin120182640.580 Why?
Cnidarian Venoms32021190.510 Why?
ATP-Binding Cassette Transporters120185600.490 Why?
Genetics, Microbial12013600.450 Why?
Endocytosis120189870.450 Why?
Biofilms220146220.410 Why?
Bacterial Vaccines420124060.370 Why?
High-Throughput Screening Assays220139410.370 Why?
Bepridil12009120.360 Why?
Thioridazine12009330.360 Why?
Disease Outbreaks1201917850.360 Why?
Repressor Proteins5200930210.350 Why?
Molecular Biology120135910.340 Why?
Antigens, Bacterial5201511770.340 Why?
Pimozide12008210.340 Why?
Flagellin320091250.340 Why?
Anti-Bacterial Agents4202172690.330 Why?
Antigens2201814660.320 Why?
Cell Line182018160040.320 Why?
Mice, Inbred BALB C8201964170.310 Why?
Interferon Type I320215500.290 Why?
Peptide Termination Factors22007550.280 Why?
rho-Associated Kinases120082780.280 Why?
Regulon22018690.270 Why?
Transcription Factors52018121650.270 Why?
Mice402021817660.270 Why?
N-Acetylglucosaminyltransferases120061690.260 Why?
Temperature2200922330.250 Why?
Autophagy6201813080.250 Why?
Promoter Regions, Genetic7200958580.250 Why?
Genes, Insect120052660.240 Why?
Cell Surface Extensions22014670.240 Why?
5' Untranslated Regions120052530.240 Why?
Animals4720211696000.240 Why?
Chlamydia Infections320153720.230 Why?
Antifungal Agents120087310.230 Why?
Vibrio cholerae319968070.230 Why?
DNA, Bacterial5200914670.230 Why?
HeLa Cells5201931250.230 Why?
Chlamydia trachomatis320152480.220 Why?
Molecular Sequence Data122009180500.220 Why?
T-Lymphocytes52013102560.220 Why?
CD8-Positive T-Lymphocytes7202145490.210 Why?
Cytotoxins120021520.200 Why?
Listeria12021270.200 Why?
DNA-Binding Proteins4200996640.200 Why?
Genome, Bacterial120067660.200 Why?
T-Lymphocytes, Cytotoxic3201818220.190 Why?
Phagocytosis4201415550.190 Why?
Dendritic Cells3202127660.190 Why?
Phagocytes220212970.190 Why?
RNA Interference2200928850.180 Why?
Cucumis melo1201910.180 Why?
Bacterial Adhesion220143160.180 Why?
Foodborne Diseases12019390.180 Why?
Food Microbiology12019780.170 Why?
Movement5200714780.160 Why?
Proteins1201360930.150 Why?
Phagosomes620212020.150 Why?
Histocompatibility Antigens Class I3201313680.150 Why?
Toll-Like Receptor 4120215750.150 Why?
Immunity, Mucosal220124920.140 Why?
Base Sequence72009127690.140 Why?
Drosophila melanogaster1200517300.130 Why?
Drosophila Proteins1200517170.130 Why?
Bacteria1200621450.130 Why?
Antipsychotic Agents1200830790.130 Why?
Actin-Related Protein 2-3 Complex12014630.120 Why?
Vesicular Transport Proteins220093760.120 Why?
Cancer Vaccines2201710410.120 Why?
Mutagenesis2201412570.120 Why?
Mice, Inbred C57BL152021220090.120 Why?
Adjuvants, Immunologic2201710440.120 Why?
Drug Evaluation, Preclinical2200913710.120 Why?
Sequence Alignment2200922500.110 Why?
Genes, Regulator119943780.110 Why?
Genetic Vectors2200434170.110 Why?
rho GTP-Binding Proteins120142910.110 Why?
Extracellular Space120145960.110 Why?
Escherichia coli3200442480.110 Why?
Leukocytes1202020560.110 Why?
Genetic Complementation Test120135600.110 Why?
Immunity, Cellular3201516100.100 Why?
Disease Models, Animal52021181740.100 Why?
Microbial Sensitivity Tests1201818850.100 Why?
Peptide Library120133510.100 Why?
Surface Properties1201411820.100 Why?
Signal Transduction32021235120.100 Why?
Neoplasms, Experimental1201712760.100 Why?
Cells, Cultured62021192700.100 Why?
Microtubule-Associated Proteins2201510840.100 Why?
Carcinoembryonic Antigen120123500.100 Why?
Cell Membrane2201837460.100 Why?
Phosphates120147820.100 Why?
Genes, Bacterial2200710810.100 Why?
Brain12018265980.100 Why?
DNA Transposable Elements120147490.100 Why?
Transfection2200258820.090 Why?
Genomics1200657430.090 Why?
Binding Sites4200961180.090 Why?
Drug Resistance, Bacterial1201810310.090 Why?
Sequence Deletion2200515220.090 Why?
Gentamicins220082540.090 Why?
Cytoplasm3201415340.090 Why?
AT Rich Sequence12009110.090 Why?
DNA Footprinting12009980.090 Why?
Fibroblasts3201341600.090 Why?
Adaptor Proteins, Signal Transducing3201529270.090 Why?
Colony Count, Microbial120093330.080 Why?
Hemolytic Plaque Technique12008660.080 Why?
Membrane Proteins4202179410.080 Why?
CD4-Positive T-Lymphocytes2201544030.080 Why?
Gene Knockdown Techniques2201416530.080 Why?
Intracellular Membranes220073910.080 Why?
Staining and Labeling1201311040.080 Why?
Histocompatibility Antigens Class II1201314690.080 Why?
Operon120093650.080 Why?
Protein Synthesis Inhibitors120081930.080 Why?
Amino Acid Sequence32009137780.080 Why?
Myosin Type II12008670.080 Why?
Microscopy, Fluorescence2201327020.080 Why?
Transcription, Genetic3200577080.080 Why?
Antibody Formation1201214070.070 Why?
Lymphocyte Activation4201855520.070 Why?
Pneumococcal Vaccines120113930.070 Why?
Vagina120128300.070 Why?
Sequence Homology, Amino Acid2200628200.070 Why?
Ovalbumin220187230.070 Why?
rhoA GTP-Binding Protein120082400.070 Why?
U937 Cells120072680.070 Why?
Lethal Dose 5012006760.070 Why?
Hemolysis120084290.070 Why?
Flow Cytometry2201759740.070 Why?
DNA, Recombinant120074760.070 Why?
Immunity, Innate3201730020.070 Why?
Multigene Family2200411010.070 Why?
Gene Expression3200677710.070 Why?
Pneumococcal Infections120115020.070 Why?
Mycobacterium fortuitum1200550.070 Why?
beta-Galactosidase219995710.070 Why?
DNA2200973120.070 Why?
Streptococcus pneumoniae120117170.060 Why?
Green Fluorescent Proteins3200620800.060 Why?
Hot Temperature1201113670.060 Why?
Gene Deletion1201327460.060 Why?
Carrier Proteins2201850060.060 Why?
Fluorescent Dyes1201319190.060 Why?
Amides120084610.060 Why?
Genetic Loci1201426140.060 Why?
Recombinant Fusion Proteins3200637610.060 Why?
Th17 Cells120117710.060 Why?
Intramolecular Oxidoreductases120041070.060 Why?
Down-Regulation1201129870.060 Why?
Liposomes220187760.060 Why?
RNA, Double-Stranded120052910.060 Why?
Species Specificity1200824830.060 Why?
HLA-A2 Antigen120042140.060 Why?
Intestines1201219240.060 Why?
Conserved Sequence1200611910.060 Why?
Transcriptional Activation1200917730.060 Why?
Repetitive Sequences, Nucleic Acid219967960.060 Why?
Escherichia coli Vaccines12002110.050 Why?
Viral Matrix Proteins120041880.050 Why?
Microarray Analysis120067660.050 Why?
Receptors, IgG120065830.050 Why?
Epithelial Cells2200737570.050 Why?
Receptors, Fc120065400.050 Why?
Inclusion Bodies, Viral12002450.050 Why?
Intestinal Mucosa3201230620.050 Why?
Intracellular Fluid120022030.050 Why?
Endoplasmic Reticulum1200811420.050 Why?
RNA Processing, Post-Transcriptional120054360.050 Why?
Female1320213850900.050 Why?
Reoviridae120021600.050 Why?
Metalloendopeptidases120034040.050 Why?
Mice, Knockout32021145960.050 Why?
Humans1920197527410.050 Why?
Vaccines, Synthetic120046350.050 Why?
Rats12018242480.050 Why?
Protein Processing, Post-Translational1200919780.050 Why?
Vaccines, DNA120023110.050 Why?
Melanoma, Experimental120045630.050 Why?
Inflammation12020107510.050 Why?
Antigen Presentation3200412730.050 Why?
Cytoskeleton1200511810.050 Why?
Genetic Testing1201334870.040 Why?
Interferon-gamma4201532200.040 Why?
Up-Regulation2200841940.040 Why?
Organic Chemicals120212110.040 Why?
Thioredoxins120202070.040 Why?
Phylogeny1200628200.040 Why?
Leupeptins120181170.040 Why?
Cross-Priming12018790.040 Why?
Lysosomes220188980.040 Why?
Genes, MHC Class I119992580.040 Why?
Phosphorylation1200984140.040 Why?
Epitopes, T-Lymphocyte220158810.040 Why?
Antibodies, Bacterial2201514750.040 Why?
Protein Transport2201519840.040 Why?
Models, Biological4201495690.040 Why?
Nucleic Acid Conformation220099160.040 Why?
Virus Internalization120215000.040 Why?
Protein Binding1200994080.040 Why?
Exocytosis120183520.040 Why?
Germ-Free Life120171910.040 Why?
Chickens119998660.040 Why?
Cell Cycle1200529670.040 Why?
Recombinant Proteins3201266240.040 Why?
Genome1200518060.040 Why?
Bacterial Load120171540.040 Why?
Genetic Engineering120029540.040 Why?
Spleen2201723690.030 Why?
Receptor, Interferon alpha-beta120161060.030 Why?
DNA Barcoding, Taxonomic120171370.030 Why?
Microtubules1200210920.030 Why?
Pyridines1200828410.030 Why?
Myeloid Cells120218150.030 Why?
Gallbladder120173060.030 Why?
Cell Proliferation22008105080.030 Why?
Ubiquitinated Proteins12015340.030 Why?
Calcium1200857740.030 Why?
Mutation42014299810.030 Why?
Interleukin-101202012050.030 Why?
Trans-Activators1200529120.030 Why?
Actin-Related Protein 212014400.030 Why?
Actin-Related Protein 312014480.030 Why?
Thiones12014460.030 Why?
Sequence Homology, Nucleic Acid1199610840.030 Why?
Viral Proteins1200218990.030 Why?
Fluorescent Antibody Technique1199924990.030 Why?
Liver3201775380.030 Why?
Immunoglobulin G1200645750.030 Why?
Inflammatory Bowel Diseases1200824460.030 Why?
Actins2201421140.030 Why?
Mice, Inbred C3H220059660.030 Why?
Chromosomes, Bacterial119942830.030 Why?
Immunotherapy, Adoptive1200213550.030 Why?
Cholera Toxin119965570.030 Why?
Uracil120141770.030 Why?
AraC Transcription Factor1199240.030 Why?
Phosphatidylserines120141930.030 Why?
Diglycerides120131760.030 Why?
Kinetics2201564820.030 Why?
Tuberculosis1200519610.030 Why?
Luminescent Proteins220068500.030 Why?
Introns119949880.030 Why?
Reactive Oxygen Species2201320870.020 Why?
United States12019707720.020 Why?
Protein Kinase Inhibitors1200855840.020 Why?
Polymerase Chain Reaction2200661690.020 Why?
Gastrointestinal Tract120178320.020 Why?
Mice, SCID2200826930.020 Why?
Blotting, Northern1199215720.020 Why?
NFATC Transcription Factors120123840.020 Why?
Proteomics2201536860.020 Why?
Genes, Reporter1201415440.020 Why?
Point Mutation1199616190.020 Why?
Mice, Transgenic3200897430.020 Why?
Phenotype22005164840.020 Why?
Dogs1201539150.020 Why?
Cell Line, Tumor12007167890.020 Why?
Amino Acid Motifs120129380.020 Why?
DNA Primers1199428800.020 Why?
Helix-Turn-Helix Motifs12009130.020 Why?
Adoptive Transfer120128420.020 Why?
Cholesterol1201829260.020 Why?
Genetic Predisposition to Disease32008176350.020 Why?
Metagenome120124200.020 Why?
Plasmids1199423160.020 Why?
Immunoglobulin A120129960.020 Why?
Cloning, Molecular1199442980.020 Why?
Regulatory Sequences, Nucleic Acid119927920.020 Why?
Cell Movement1202052220.020 Why?
Immune Evasion120123600.020 Why?
Ubiquitination1201310120.020 Why?
Tyrosine1201214620.020 Why?
Paneth Cells12008990.020 Why?
Ampicillin120081400.020 Why?
Protein Isoforms1201217310.020 Why?
Protein Structure, Tertiary1201438370.020 Why?
Centrifugation120071220.020 Why?
Glass120071140.020 Why?
Adhesins, Bacterial120071200.020 Why?
Dose-Response Relationship, Drug11999109140.020 Why?
Immunization1201112540.020 Why?
Receptors, Immunologic1201214360.020 Why?
rab5 GTP-Binding Proteins12006500.020 Why?
Alanine Racemase1200550.020 Why?
Animals, Congenic12005270.020 Why?
Enzyme Activation1201136740.020 Why?
Microscopy, Electron, Transmission120077100.020 Why?
Phosphatidylinositol Phosphates120062090.020 Why?
Cell Compartmentation120063970.020 Why?
Interleukin-17120119080.020 Why?
Kanamycin12004630.010 Why?
Polymorphism, Genetic2200543270.010 Why?
RNA, Messenger22005130110.010 Why?
rab GTP-Binding Proteins120062480.010 Why?
Minor Histocompatibility Antigens120052980.010 Why?
Glycosylation1200711290.010 Why?
Cell Differentiation12021115530.010 Why?
Microscopy, Immunoelectron120023200.010 Why?
Endopeptidases120067880.010 Why?
Hybridomas120024490.010 Why?
Homeostasis1201233430.010 Why?
Transgenes1200510120.010 Why?
Macrophage Activation120045660.010 Why?
Cysteine Endopeptidases120045530.010 Why?
Protein Conformation1200940100.010 Why?
Immunologic Memory1200813600.010 Why?
Necrosis1200516410.010 Why?
Apoptosis2200896570.010 Why?
Multienzyme Complexes120046690.010 Why?
Influenza A virus120044660.010 Why?
Models, Molecular1200954600.010 Why?
Bone Marrow Cells1200624910.010 Why?
Cricetinae1200224710.010 Why?
Proteasome Endopeptidase Complex1200413200.010 Why?
Cytokines1201274000.010 Why?
Receptors, Antigen, T-Cell1200625550.010 Why?
Time Factors11999401950.010 Why?
Bone Marrow Transplantation1200527390.010 Why?
Male320213543110.010 Why?
Colitis, Ulcerative1200819360.010 Why?
Chromosome Mapping1200447230.010 Why?
Nitric Oxide1200421520.010 Why?
Crohn Disease1200823210.010 Why?
Killer Cells, Natural1200421610.010 Why?
Lymph Nodes1200635030.010 Why?
Tumor Cells, Cultured1200262330.010 Why?
Mycobacterium tuberculosis1200518890.010 Why?
Neoplasms12002219760.010 Why?
Chronic Disease1200892230.010 Why?
Sequence Analysis, DNA1200248060.010 Why?
Survival Rate12005128020.010 Why?
Nuclear Proteins1200558510.010 Why?
Young Adult12015572670.010 Why?
Disease Progression12005133640.000 Why?
Gene Expression Regulation12006120540.000 Why?
Genotype12002129700.000 Why?
Adolescent12015867130.000 Why?
Lung1200599900.000 Why?
Middle Aged120152160540.000 Why?
Adult120152166580.000 Why?
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Concepts (360)
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.