Alanine Racemase

"Alanine Racemase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A pyridoxal-phosphate protein that reversibly catalyzes the conversion of L-alanine to D-alanine. EC 5.1.1.1.

Descriptor ID

D000411

MeSH Number(s)

D08.811.399.894.200.200

Concept/Terms

Alanine Racemase

Below are MeSH descriptors whose meaning is more general than "Alanine Racemase".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Isomerases [D08.811.399]
Racemases and Epimerases [D08.811.399.894]
Amino Acid Isomerases [D08.811.399.894.200]
Alanine Racemase [D08.811.399.894.200.200]

Below are MeSH descriptors whose meaning is related to "Alanine Racemase".

Below are MeSH descriptors whose meaning is more specific than "Alanine Racemase".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Alanine Racemase" by people in Harvard Catalyst Profiles by year, and whether "Alanine Racemase" was a major or minor topic of these publication.

Bar chart showing 4 publications over 4 distinct years, with a maximum of 1 publications in 1997 and 1999 and 2005 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	1	0	1
1999	1	0	1
2005	0	1	1
2013	0	1	1

Below are the most recent publications written about "Alanine Racemase" by people in Profiles.

Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance. Nat Genet. 2016 05; 48(5):544-51.

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D-Alanine-Controlled Transient Intestinal Mono-Colonization with Non-Laboratory-Adapted Commensal E. coli Strain HS. PLoS One. 2016; 11(3):e0151872.

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The structure of alanine racemase from Acinetobacter baumannii. Acta Crystallogr F Struct Biol Commun. 2014 Sep; 70(Pt 9):1199-205.

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Structural basis for the broad specificity of a new family of amino-acid racemases. Acta Crystallogr D Biol Crystallogr. 2014 Jan; 70(Pt 1):79-90.

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Structural features and kinetic characterization of alanine racemase from Staphylococcus aureus (Mu50). Acta Crystallogr D Biol Crystallogr. 2012 Jan; 68(Pt 1):82-92.

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New classes of alanine racemase inhibitors identified by high-throughput screening show antimicrobial activity against Mycobacterium tuberculosis. PLoS One. 2011; 6(5):e20374.

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The crystal structure of alanine racemase from Streptococcus pneumoniae, a target for structure-based drug design. BMC Microbiol. 2011 May 25; 11:116.

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Biochemical and structural characterization of alanine racemase from Bacillus anthracis (Ames). BMC Struct Biol. 2009 Aug 20; 9:53.

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Biochemical characterization of alanine racemase--a spore protein produced by Bacillus anthracis. BMB Rep. 2009 Jan 31; 42(1):47-52.

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The alanine racemase of Mycobacterium smegmatis is essential for growth in the absence of D-alanine. J Bacteriol. 2007 Nov; 189(22):8381-6.

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