Sin3 Histone Deacetylase and Corepressor Complex
"Sin3 Histone Deacetylase and Corepressor Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multisubunit enzyme complex that regulates GENETIC TRANSCRIPTION by deacetylating the HISTONE residues of NUCLEOSOMES.
MeSH Number(s)
D08.811.277.087.520.750
D08.811.600.795
D12.776.930.700.625.750
Concept/Terms
Sin3 Histone Deacetylase and Corepressor Complex- Sin3 Histone Deacetylase and Corepressor Complex
- SIN3 Complex
- SIN3 Histone Deacetylase Complex
- Sin3-Histone Deacetylase (HDAC) Corepressor Complex
- SIN-3 Histone Deacetylase Complex
- SIN 3 Histone Deacetylase Complex
- Sin3 Corepressor Complex
- Corepressor Complex, Sin3
Below are MeSH descriptors whose meaning is more general than "Sin3 Histone Deacetylase and Corepressor Complex".
Below are MeSH descriptors whose meaning is more specific than "Sin3 Histone Deacetylase and Corepressor Complex".
This graph shows the total number of publications written about "Sin3 Histone Deacetylase and Corepressor Complex" by people in Harvard Catalyst Profiles by year, and whether "Sin3 Histone Deacetylase and Corepressor Complex" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2014 | 0 | 1 | 1 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
Below are the most recent publications written about "Sin3 Histone Deacetylase and Corepressor Complex" by people in Profiles.
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Regulation of the Methylation and Expression Levels of the BMPR2 Gene by SIN3a as a Novel Therapeutic Mechanism in Pulmonary Arterial Hypertension. Circulation. 2021 07 06; 144(1):52-73.
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Comprehensive study of 28 individuals with SIN3A-related disorder underscoring the associated mild cognitive and distinctive facial phenotype. Eur J Hum Genet. 2021 04; 29(4):625-636.
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ARID4B is critical for mouse embryonic stem cell differentiation towards mesoderm and endoderm, linking epigenetics to pluripotency exit. J Biol Chem. 2020 12 18; 295(51):17738-17751.
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A role for H3K4 monomethylation in gene repression and partitioning of chromatin readers. Mol Cell. 2014 Mar 20; 53(6):979-92.
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Epstein-Barr virus nuclear antigen 3C binds to BATF/IRF4 or SPI1/IRF4 composite sites and recruits Sin3A to repress CDKN2A. Proc Natl Acad Sci U S A. 2014 Jan 07; 111(1):421-6.
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Epigenetic silencing of the proapoptotic gene BIM in anaplastic large cell lymphoma through an MeCP2/SIN3a deacetylating complex. Neoplasia. 2013 May; 15(5):511-22.
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A molecular mechanism for circadian clock negative feedback. Science. 2011 Jun 17; 332(6036):1436-9.
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Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug; 28(8):1424-34.
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A role for mammalian Sin3 in permanent gene silencing. Mol Cell. 2008 Nov 07; 32(3):359-70.
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Genetic identification of a network of factors that functionally interact with the nucleosome remodeling ATPase ISWI. PLoS Genet. 2008 Jun 06; 4(6):e1000089.