Mi-2 Nucleosome Remodeling and Deacetylase Complex
"Mi-2 Nucleosome Remodeling and Deacetylase Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A enzyme complex involved in the remodeling of NUCLEOSOMES. The complex is comprised of at least seven subunits and includes both histone deacetylase and ATPase activities.
MeSH Number(s)
D08.811.277.040.025.176
D08.811.277.087.520.500
D08.811.600.620
Concept/Terms
Mi-2 Nucleosome Remodeling and Deacetylase Complex- Mi-2 Nucleosome Remodeling and Deacetylase Complex
- Mi 2 Nucleosome Remodeling and Deacetylase Complex
- NuRD Histone Deacetylase Complex
- Nucleosome Remodeling and Deacetylase Complex
- NuRD Complex
- Complex, NuRD
- Histone Deacetylase Complex MI-2
- Histone Deacetylase Complex MI 2
- Histone Deacetylase Complex NuRD
Below are MeSH descriptors whose meaning is more general than "Mi-2 Nucleosome Remodeling and Deacetylase Complex".
Below are MeSH descriptors whose meaning is more specific than "Mi-2 Nucleosome Remodeling and Deacetylase Complex".
This graph shows the total number of publications written about "Mi-2 Nucleosome Remodeling and Deacetylase Complex" by people in Harvard Catalyst Profiles by year, and whether "Mi-2 Nucleosome Remodeling and Deacetylase Complex" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2001 | 0 | 2 | 2 |
| 2004 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 2 | 4 |
| 2012 | 0 | 2 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 3 | 3 | 6 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 4 | 1 | 5 |
| 2019 | 5 | 2 | 7 |
| 2020 | 4 | 2 | 6 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 1 | 2 |
| 2023 | 0 | 4 | 4 |
| 2024 | 1 | 0 | 1 |
Below are the most recent publications written about "Mi-2 Nucleosome Remodeling and Deacetylase Complex" by people in Profiles.
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The Chromatin Remodeler CHD4 Sustains Ewing Sarcoma Cell Survival by Controlling Global Chromatin Architecture. Cancer Res. 2024 01 16; 84(2):241-257.
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Collateral lethality between HDAC1 and HDAC2 exploits cancer-specific NuRD complex vulnerabilities. Nat Struct Mol Biol. 2023 08; 30(8):1160-1171.
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Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1. Circ Res. 2023 06 23; 133(1):48-67.
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Chromodomain helicase DNA binding protein 4 in cell fate decisions. Hear Res. 2023 09 01; 436:108813.
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Chromatin complex dependencies reveal targeting opportunities in leukemia. Nat Commun. 2023 01 27; 14(1):448.
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ARID1A-dependent maintenance of H3.3 is required for repressive CHD4-ZMYND8 chromatin interactions at super-enhancers. BMC Biol. 2022 09 25; 20(1):209.
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CHD4 is recruited by GATA4 and NKX2-5 to repress noncardiac gene programs in the developing heart. Genes Dev. 2022 04 01; 36(7-8):468-482.
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ZNF410 represses fetal globin by singular control of CHD4. Nat Genet. 2021 05; 53(5):719-728.
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ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression. Mol Cell. 2021 01 21; 81(2):239-254.e8.
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BRD4 prevents the accumulation of R-loops and protects against transcription-replication collision events and DNA damage. Nat Commun. 2020 08 14; 11(1):4083.