Phosphoenolpyruvate Sugar Phosphotransferase System
"Phosphoenolpyruvate Sugar Phosphotransferase System" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The bacterial sugar phosphotransferase system (PTS) that catalyzes the transfer of the phosphoryl group from phosphoenolpyruvate to its sugar substrates (the PTS sugars) concomitant with the translocation of these sugars across the bacterial membrane. The phosphorylation of a given sugar requires four proteins, two general proteins, Enzyme I and HPr and a pair of sugar-specific proteins designated as the Enzyme II complex. The PTS has also been implicated in the induction of synthesis of some catabolic enzyme systems required for the utilization of sugars that are not substrates of the PTS as well as the regulation of the activity of adenylate cyclase. EC 2.7.1.-.
MeSH Number(s)
D05.500.562.484
D08.811.600.700
D08.811.913.696.620.650
Concept/Terms
Phosphoenolpyruvate-Glycose Phosphotransferase System- Phosphoenolpyruvate-Glycose Phosphotransferase System
- Phosphoenolpyruvate Glycose Phosphotransferase System
- Phosphotransferase System, Phosphoenolpyruvate-Glycose
- System, Phosphoenolpyruvate-Glycose Phosphotransferase
Below are MeSH descriptors whose meaning is more general than "Phosphoenolpyruvate Sugar Phosphotransferase System".
Below are MeSH descriptors whose meaning is more specific than "Phosphoenolpyruvate Sugar Phosphotransferase System".
This graph shows the total number of publications written about "Phosphoenolpyruvate Sugar Phosphotransferase System" by people in Harvard Catalyst Profiles by year, and whether "Phosphoenolpyruvate Sugar Phosphotransferase System" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2002 | 1 | 1 | 2 |
| 2003 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2010 | 2 | 0 | 2 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 2 | 0 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
Below are the most recent publications written about "Phosphoenolpyruvate Sugar Phosphotransferase System" by people in Profiles.
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Determinants of target prioritization and regulatory hierarchy for the bacterial small RNA SgrS. Mol Microbiol. 2019 10; 112(4):1199-1218.
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Removal of a Membrane Anchor Reveals the Opposing Regulatory Functions of Vibrio cholerae Glucose-Specific Enzyme IIA in Biofilms and the Mammalian Intestine. mBio. 2018 09 04; 9(5).
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Plasma and Mucosal Immunoglobulin M, Immunoglobulin A, and Immunoglobulin G Responses to the Vibrio cholerae O1 Protein Immunome in Adults With Cholera in Bangladesh. J Infect Dis. 2017 07 01; 216(1):125-134.
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Electron crystallography reveals that substrate release from the PTS IIC glucose transporter is coupled to a subtle conformational change. J Struct Biol. 2017 07; 199(1):39-45.
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Regulation of CsrB/C sRNA decay by EIIA(Glc) of the phosphoenolpyruvate: carbohydrate phosphotransferase system. Mol Microbiol. 2016 Feb; 99(4):627-39.
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2D and 3D crystallization of the wild-type IIC domain of the glucose PTS transporter from Escherichia coli. J Struct Biol. 2015 Sep; 191(3):376-80.
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A Single Host-Derived Glycan Impacts Key Regulatory Nodes of Symbiont Metabolism in a Coevolved Mutualism. mBio. 2015 Jul 14; 6(4):e00811.
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A Genome-Wide Screen Reveals that the Vibrio cholerae Phosphoenolpyruvate Phosphotransferase System Modulates Virulence Gene Expression. Infect Immun. 2015 Sep; 83(9):3381-95.
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Genome-wide mutant fitness profiling identifies nutritional requirements for optimal growth of Yersinia pestis in deep tissue. mBio. 2014 Aug 19; 5(4).
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Glucose-specific enzyme IIA has unique binding partners in the vibrio cholerae biofilm. mBio. 2012 Nov 06; 3(6):e00228-12.