gamma-Globins

"gamma-Globins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Members of the beta-globin family. In humans, two non-allelic types of gamma-globin - A gamma and G gamma are encoded in the beta-globin gene cluster on CHROMOSOME 11. Two gamma-globin chains combine with two ZETA-GLOBIN chains to form the embryonic hemoglobin Portland. Fetal HEMOGLOBIN F is formed from two gamma-globin chains combined with two ALPHA-GLOBIN chains.

Descriptor ID

D055545

MeSH Number(s)

D12.776.124.400.434.325.500

D12.776.422.316.762.403.325.500

Concept/Terms

gamma-Globins

A gamma-Globin

G gamma-Globin

Below are MeSH descriptors whose meaning is more general than "gamma-Globins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Hemoglobins [D12.776.124.400]
Hemoglobin Subunits [D12.776.124.400.434]
beta-Globins [D12.776.124.400.434.325]
gamma-Globins [D12.776.124.400.434.325.500]
Hemeproteins [D12.776.422]
Globins [D12.776.422.316]
Hemoglobins [D12.776.422.316.762]
Hemoglobin Subunits [D12.776.422.316.762.403]
beta-Globins [D12.776.422.316.762.403.325]
gamma-Globins [D12.776.422.316.762.403.325.500]

Below are MeSH descriptors whose meaning is related to "gamma-Globins".

Below are MeSH descriptors whose meaning is more specific than "gamma-Globins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "gamma-Globins" by people in Harvard Catalyst Profiles by year, and whether "gamma-Globins" was a major or minor topic of these publication.

Bar chart showing 34 publications over 17 distinct years, with a maximum of 5 publications in 2016

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2008	0	1	1
2009	0	1	1
2010	2	1	3
2011	2	1	3
2012	1	0	1
2013	1	0	1
2014	1	1	2
2015	1	1	2
2016	5	0	5
2017	0	1	1
2018	0	2	2
2019	1	3	4
2020	2	0	2
2021	1	0	1
2022	1	2	3
2023	0	1	1
2024	0	1	1

Below are the most recent publications written about "gamma-Globins" by people in Profiles.

Peripheral blood circular RNA circ-0008102 may serve as a novel clinical biomarker in beta-thalassemia patients. Eur J Pediatr. 2024 Mar; 183(3):1367-1379.

View in: PubMed
Therapeutic adenine base editing of human hematopoietic stem cells. Nat Commun. 2023 01 13; 14(1):207.

View in: PubMed
Transient neonatal hemolytic anemia due to the novel gamma globin gene mutation HBG2:C.290T>C, p.Leu97Pro (hemoglobin Wareham). Pediatr Blood Cancer. 2023 Jan; 70(1):e30067.

View in: PubMed
miRNA Expression Associated with HbF in Saudi Sickle Cell Anemia. Medicina (Kaunas). 2022 Oct 17; 58(10).

View in: PubMed
Development of a double shmiR lentivirus effectively targeting both BCL11A and ZNF410 for enhanced induction of fetal hemoglobin to treat ß-hemoglobinopathies. Mol Ther. 2022 08 03; 30(8):2693-2708.

View in: PubMed
Transcription factor competition at the ?-globin promoters controls hemoglobin switching. Nat Genet. 2021 04; 53(4):511-520.

View in: PubMed
Post-Transcriptional Genetic Silencing of BCL11A to Treat Sickle Cell Disease. N Engl J Med. 2021 01 21; 384(3):205-215.

View in: PubMed
Therapeutic base editing of human hematopoietic stem cells. Nat Med. 2020 04; 26(4):535-541.

View in: PubMed
Genome editing of HBG1 and HBG2 to induce fetal hemoglobin. Blood Adv. 2019 11 12; 3(21):3379-3392.

View in: PubMed
Zfp281 (ZBP-99) plays a functionally redundant role with Zfp148 (ZBP-89) during erythroid development. Blood Adv. 2019 08 27; 3(16):2499-2511.

View in: PubMed

Related Networks

People

Explore

Similar Concepts

Top Journals

Blood
Science
Am J Hematol
Nat Med
Hum Mol Genet
Genes Dev
Blood Adv
FASEB J
Dig Liver Dis
Clin Exp Pharmacol Physiol