"Astrocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.
Below are MeSH descriptors whose meaning is more general than "Astrocytes".
Below are MeSH descriptors whose meaning is more specific than "Astrocytes".
This graph shows the total number of publications written about "Astrocytes" by people in Harvard Catalyst Profiles by year, and whether "Astrocytes" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 3 | 7 | 10 |
| 1994 | 5 | 2 | 7 |
| 1995 | 3 | 4 | 7 |
| 1996 | 5 | 4 | 9 |
| 1997 | 6 | 6 | 12 |
| 1998 | 8 | 5 | 13 |
| 1999 | 9 | 6 | 15 |
| 2000 | 11 | 7 | 18 |
| 2001 | 6 | 6 | 12 |
| 2002 | 17 | 9 | 26 |
| 2003 | 3 | 13 | 16 |
| 2004 | 14 | 13 | 27 |
| 2005 | 11 | 7 | 18 |
| 2006 | 15 | 10 | 25 |
| 2007 | 5 | 17 | 22 |
| 2008 | 13 | 15 | 28 |
| 2009 | 8 | 19 | 27 |
| 2010 | 14 | 12 | 26 |
| 2011 | 14 | 8 | 22 |
| 2012 | 20 | 22 | 42 |
| 2013 | 15 | 11 | 26 |
| 2014 | 16 | 21 | 37 |
| 2015 | 22 | 11 | 33 |
| 2016 | 15 | 14 | 29 |
| 2017 | 33 | 20 | 53 |
| 2018 | 22 | 20 | 42 |
| 2019 | 23 | 23 | 46 |
| 2020 | 20 | 23 | 43 |
| 2021 | 22 | 9 | 31 |
| 2022 | 8 | 14 | 22 |
Below are the most recent publications written about "Astrocytes" by people in Profiles.
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The D-serine biosynthetic enzyme serine racemase is expressed by reactive astrocytes in the amygdala of human and a mouse model of Alzheimer's disease. Neurosci Lett. 2023 Jan 01; 792:136958.
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APOE4 derived from astrocytes leads to blood-brain barrier impairment. Brain. 2022 10 21; 145(10):3582-3593.
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Activity-dependent translation dynamically alters the proteome of the perisynaptic astrocyte process. Cell Rep. 2022 10 18; 41(3):111474.
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Elucidating the diversity of malignant mesenchymal states in glioblastoma by integrative analysis. Genome Med. 2022 09 19; 14(1):106.
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SARS-CoV-2 infection impacts carbon metabolism and depends on glutamine for replication in Syrian hamster astrocytes. J Neurochem. 2022 10; 163(2):113-132.
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Morphological, cellular, and molecular basis of brain infection in COVID-19 patients. Proc Natl Acad Sci U S A. 2022 08 30; 119(35):e2200960119.
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Neuroinflammation in neurodegeneration via microbial infections. Front Immunol. 2022; 13:907804.
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In SARS-CoV-2, astrocytes are in it for the long haul. Proc Natl Acad Sci U S A. 2022 07 26; 119(30):e2209130119.
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Sera of Neuromyelitis Optica Patients Increase BID-Mediated Apoptosis in Astrocytes. Int J Mol Sci. 2022 Jun 27; 23(13).
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Astrocytes and Microglia in Stress-Induced Neuroinflammation: The African Perspective. Front Immunol. 2022; 13:795089.