"Astrocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.
Below are MeSH descriptors whose meaning is more general than "Astrocytes".
Below are MeSH descriptors whose meaning is more specific than "Astrocytes".
This graph shows the total number of publications written about "Astrocytes" by people in Harvard Catalyst Profiles by year, and whether "Astrocytes" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1991 | 3 | 2 | 5 |
| 1992 | 4 | 5 | 9 |
| 1993 | 2 | 7 | 9 |
| 1994 | 5 | 2 | 7 |
| 1995 | 3 | 4 | 7 |
| 1996 | 5 | 4 | 9 |
| 1997 | 6 | 6 | 12 |
| 1998 | 8 | 5 | 13 |
| 1999 | 9 | 8 | 17 |
| 2000 | 10 | 8 | 18 |
| 2001 | 4 | 6 | 10 |
| 2002 | 15 | 9 | 24 |
| 2003 | 3 | 12 | 15 |
| 2004 | 16 | 13 | 29 |
| 2005 | 12 | 7 | 19 |
| 2006 | 17 | 9 | 26 |
| 2007 | 5 | 16 | 21 |
| 2008 | 12 | 15 | 27 |
| 2009 | 10 | 19 | 29 |
| 2010 | 14 | 12 | 26 |
| 2011 | 14 | 13 | 27 |
| 2012 | 20 | 22 | 42 |
| 2013 | 18 | 15 | 33 |
| 2014 | 21 | 23 | 44 |
| 2015 | 23 | 12 | 35 |
| 2016 | 16 | 15 | 31 |
| 2017 | 30 | 19 | 49 |
| 2018 | 23 | 20 | 43 |
| 2019 | 20 | 22 | 42 |
| 2020 | 17 | 19 | 36 |
| 2021 | 4 | 1 | 5 |
Below are the most recent publications written about "Astrocytes" by people in Profiles.
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Human sensorimotor organoids derived from healthy and amyotrophic lateral sclerosis stem cells form neuromuscular junctions. Nat Commun. 2021 08 06; 12(1):4744.
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Barcoded viral tracing of single-cell interactions in central nervous system inflammation. Science. 2021 04 23; 372(6540).
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Selective removal of astrocytic APOE4 strongly protects against tau-mediated neurodegeneration and decreases synaptic phagocytosis by microglia. Neuron. 2021 05 19; 109(10):1657-1674.e7.
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Jararhagin, a snake venom metalloproteinase, induces mechanical hyperalgesia in mice with the neuroinflammatory contribution of spinal cord microglia and astrocytes. Int J Biol Macromol. 2021 May 15; 179:610-619.
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Reactive astrocyte nomenclature, definitions, and future directions. Nat Neurosci. 2021 03; 24(3):312-325.
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Mutant Huntingtin Is Cleared from the Brain via Active Mechanisms in Huntington Disease. J Neurosci. 2021 01 27; 41(4):780-796.
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Neuropathological correlates of cortical superficial siderosis in cerebral amyloid angiopathy. Brain. 2020 12 05; 143(11):3343-3351.
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Astrocyte deletion of a2-Na/K ATPase triggers episodic motor paralysis in mice via a metabolic pathway. Nat Commun. 2020 12 02; 11(1):6164.
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Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis. Cell. 2020 12 10; 183(6):1617-1633.e22.
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Extracellular Vesicle-Mediated Bilateral Communication between Glioblastoma and Astrocytes. Trends Neurosci. 2021 03; 44(3):215-226.