"Astrocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord. Astrocytes (from "star" cells) are irregularly shaped with many long processes, including those with "end feet" which form the glial (limiting) membrane and directly and indirectly contribute to the BLOOD-BRAIN BARRIER. They regulate the extracellular ionic and chemical environment, and "reactive astrocytes" (along with MICROGLIA) respond to injury.
Below are MeSH descriptors whose meaning is more general than "Astrocytes".
Below are MeSH descriptors whose meaning is more specific than "Astrocytes".
This graph shows the total number of publications written about "Astrocytes" by people in Harvard Catalyst Profiles by year, and whether "Astrocytes" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 3 | 7 | 10 |
| 1994 | 5 | 2 | 7 |
| 1995 | 2 | 4 | 6 |
| 1996 | 5 | 4 | 9 |
| 1997 | 6 | 6 | 12 |
| 1998 | 8 | 5 | 13 |
| 1999 | 10 | 6 | 16 |
| 2000 | 11 | 7 | 18 |
| 2001 | 6 | 6 | 12 |
| 2002 | 15 | 10 | 25 |
| 2003 | 3 | 13 | 16 |
| 2004 | 14 | 14 | 28 |
| 2005 | 11 | 8 | 19 |
| 2006 | 14 | 10 | 24 |
| 2007 | 7 | 18 | 25 |
| 2008 | 12 | 15 | 27 |
| 2009 | 7 | 19 | 26 |
| 2010 | 15 | 11 | 26 |
| 2011 | 14 | 9 | 23 |
| 2012 | 21 | 21 | 42 |
| 2013 | 13 | 12 | 25 |
| 2014 | 17 | 19 | 36 |
| 2015 | 23 | 10 | 33 |
| 2016 | 17 | 12 | 29 |
| 2017 | 28 | 18 | 46 |
| 2018 | 21 | 20 | 41 |
| 2019 | 23 | 21 | 44 |
| 2020 | 20 | 22 | 42 |
| 2021 | 24 | 11 | 35 |
| 2022 | 10 | 16 | 26 |
| 2023 | 12 | 16 | 28 |
Below are the most recent publications written about "Astrocytes" by people in Profiles.
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Neuroinflammation: An astrocyte perspective. Sci Transl Med. 2023 Nov 08; 15(721):eadi7828.
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Rapid isolation of intact retinal astrocytes: a novel approach. Acta Neuropathol Commun. 2023 09 25; 11(1):154.
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Astrocytes in Parkinson's Disease: From Role to Possible Intervention. Cells. 2023 09 22; 12(19).
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Copper induces neuron-sparing, ferredoxin 1-independent astrocyte toxicity mediated by oxidative stress. J Neurochem. 2023 10; 167(2):277-295.
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Astrocytes on steroids binge on synapses to cope with stress. Immunity. 2023 09 12; 56(9):1983-1985.
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PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation. Nat Commun. 2023 09 09; 14(1):5555.
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Astrocytes in the Optic Nerve Are Heterogeneous in Their Reactivity to Glaucomatous Injury. Cells. 2023 08 23; 12(17).
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Building transformers from neurons and astrocytes. Proc Natl Acad Sci U S A. 2023 08 22; 120(34):e2219150120.
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Optogenetic targeting of astrocytes restores slow brain rhythm function and slows Alzheimer's disease pathology. Sci Rep. 2023 08 11; 13(1):13075.
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Mitochondria dysregulation contributes to secondary neurodegeneration progression post-contusion injury in human 3D in vitro triculture brain tissue model. Cell Death Dis. 2023 08 03; 14(8):496.