"Microglia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The third type of glial cell, along with astrocytes and oligodendrocytes (which together form the macroglia). Microglia vary in appearance depending on developmental stage, functional state, and anatomical location; subtype terms include ramified, perivascular, ameboid, resting, and activated. Microglia clearly are capable of phagocytosis and play an important role in a wide spectrum of neuropathologies. They have also been suggested to act in several other roles including in secretion (e.g., of cytokines and neural growth factors), in immunological processing (e.g., antigen presentation), and in central nervous system development and remodeling.
Below are MeSH descriptors whose meaning is more general than "Microglia".
Below are MeSH descriptors whose meaning is more specific than "Microglia".
This graph shows the total number of publications written about "Microglia" by people in Harvard Catalyst Profiles by year, and whether "Microglia" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 1 | 0 | 1 |
| 1994 | 1 | 1 | 2 |
| 1996 | 4 | 1 | 5 |
| 1997 | 6 | 1 | 7 |
| 1998 | 6 | 8 | 14 |
| 1999 | 5 | 2 | 7 |
| 2000 | 1 | 4 | 5 |
| 2001 | 3 | 4 | 7 |
| 2002 | 5 | 5 | 10 |
| 2003 | 8 | 2 | 10 |
| 2004 | 3 | 2 | 5 |
| 2005 | 9 | 5 | 14 |
| 2006 | 9 | 9 | 18 |
| 2007 | 10 | 8 | 18 |
| 2008 | 19 | 6 | 25 |
| 2009 | 9 | 9 | 18 |
| 2010 | 6 | 10 | 16 |
| 2011 | 8 | 9 | 17 |
| 2012 | 12 | 7 | 19 |
| 2013 | 14 | 10 | 24 |
| 2014 | 14 | 10 | 24 |
| 2015 | 26 | 12 | 38 |
| 2016 | 24 | 6 | 30 |
| 2017 | 32 | 18 | 50 |
| 2018 | 40 | 21 | 61 |
| 2019 | 36 | 29 | 65 |
| 2020 | 42 | 18 | 60 |
| 2021 | 29 | 30 | 59 |
| 2022 | 18 | 25 | 43 |
| 2023 | 2 | 3 | 5 |
Below are the most recent publications written about "Microglia" by people in Profiles.
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Droplet-based forward genetic screening of astrocyte-microglia cross-talk. Science. 2023 03 10; 379(6636):1023-1030.
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Microglia refine developing retinal astrocytic and vascular networks through the complement C3/C3aR axis. Development. 2023 03 01; 150(5).
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Definition of the contribution of an Osteopontin-producing CD11c+ microglial subset to Alzheimer's disease. Proc Natl Acad Sci U S A. 2023 02 07; 120(6):e2218915120.
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The neuroimmune axis of Alzheimer's disease. Genome Med. 2023 01 26; 15(1):6.
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Inhibitor of NF-?B Kinase Subunit e Contributes to Neuropsychiatric Manifestations in Lupus-Prone Mice Through Microglial Activation. Arthritis Rheumatol. 2023 03; 75(3):411-423.
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Identification and Prioritization of PET Neuroimaging Targets for Microglial Phenotypes Associated with Microglial Activity in Alzheimer's Disease. ACS Chem Neurosci. 2022 12 21; 13(24):3641-3660.
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Molecular and spatial heterogeneity of microglia in Rasmussen encephalitis. Acta Neuropathol Commun. 2022 11 21; 10(1):168.
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Microglia states and nomenclature: A field at its crossroads. Neuron. 2022 11 02; 110(21):3458-3483.
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Sex differences in Alzheimer's disease risk: are immune responses the key? Brain. 2022 10 21; 145(10):3341-3342.
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Phytochemical Combination Is More Effective than Individual Components in Reducing Stress Signaling in Rat Hippocampal Neurons and Microglia In Vitro. Int J Mol Sci. 2022 Oct 21; 23(20).