Proteinase Inhibitory Proteins, Secretory
"Proteinase Inhibitory Proteins, Secretory" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Peptides and proteins found in BODILY SECRETIONS and BODY FLUIDS that are PROTEASE INHIBITORS. They play a role in INFLAMMATION, tissue repair and innate immunity (IMMUNITY, INNATE) by inhibiting endogenous proteinases such as those produced by LEUKOCYTES and exogenous proteases such as those produced by invading microorganisms.
Below are MeSH descriptors whose meaning is more general than "Proteinase Inhibitory Proteins, Secretory".
Below are MeSH descriptors whose meaning is more specific than "Proteinase Inhibitory Proteins, Secretory".
This graph shows the total number of publications written about "Proteinase Inhibitory Proteins, Secretory" by people in Harvard Catalyst Profiles by year, and whether "Proteinase Inhibitory Proteins, Secretory" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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1997 | 0 | 2 | 2 |
1999 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2004 | 0 | 1 | 1 |
2005 | 0 | 4 | 4 |
2006 | 0 | 2 | 2 |
2007 | 2 | 0 | 2 |
2008 | 2 | 3 | 5 |
2009 | 2 | 0 | 2 |
2010 | 1 | 1 | 2 |
2011 | 0 | 1 | 1 |
2012 | 2 | 0 | 2 |
2013 | 2 | 1 | 3 |
2014 | 1 | 0 | 1 |
2015 | 0 | 1 | 1 |
2016 | 1 | 2 | 3 |
2017 | 1 | 0 | 1 |
2019 | 2 | 1 | 3 |
2020 | 1 | 0 | 1 |
2021 | 1 | 1 | 2 |
2022 | 2 | 0 | 2 |
2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Proteinase Inhibitory Proteins, Secretory" by people in Profiles.
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Possible role of combined therapy targeting MET and pro-HGF activation for renal cell carcinoma: analysis by human HGF-producing SCID mice. Hum Cell. 2023 Mar; 36(2):775-785.
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Insufficiency of hepatocyte growth factor activator inhibitor-1 confers lymphatic invasion of tongue carcinoma cells. Cancer Sci. 2022 Jun; 113(6):2179-2193.
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Role of the polycystic kidney disease domain in matriptase chaperone activity and localization of hepatocyte growth factor activator inhibitor-1. FEBS J. 2022 06; 289(12):3422-3439.
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Alternative poly-adenylation modulates a1-antitrypsin expression in chronic obstructive pulmonary disease. PLoS Genet. 2021 11; 17(11):e1009912.
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Maternal circulating SPINT1 is reduced in small-for-gestational age pregnancies at 26 weeks: Growing up in Singapore towards health outcomes (GUSTO) cohort study. Placenta. 2021 07; 110:24-28.
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Protease-activated receptor-2 accelerates intestinal tumor formation through activation of nuclear factor-?B signaling and tumor angiogenesis in ApcMin/+ mice. Cancer Sci. 2020 Apr; 111(4):1193-1202.
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Neutrophil Elastase Inhibitors Suppress Oxidative Stress in Lung during Liver Transplantation. Oxid Med Cell Longev. 2019; 2019:7323986.
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Zebrafish modeling reveals that SPINT1 regulates the aggressiveness of skin cutaneous melanoma and its crosstalk with tumor immune microenvironment. J Exp Clin Cancer Res. 2019 Sep 13; 38(1):405.
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Circulating microparticle proteins obtained in the late first trimester predict spontaneous preterm birth at less than 35 weeks' gestation: a panel validation with specific characterization by parity. Am J Obstet Gynecol. 2019 05; 220(5):488.e1-488.e11.
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Prognostic significance of hepatocyte growth factor activator inhibitor type 1 (HAI-1) immunoreactivity in pancreatic ductal adenocarcinoma. BMC Res Notes. 2017 Dec 04; 10(1):674.