Smad1 Protein

"Smad1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A receptor-regulated smad protein that undergoes PHOSPHORYLATION by BONE MORPHOGENETIC PROTEIN RECEPTORS. It regulates BONE MORPHOGENETIC PROTEIN signaling and plays an essential role in EMBRYONIC DEVELOPMENT.

Descriptor ID

D051898

MeSH Number(s)

D12.644.360.024.334.500.100

D12.776.157.057.170.500.100

D12.776.260.713.500.100

D12.776.476.024.417.500.100

D12.776.744.741.500

D12.776.930.806.500.100

Concept/Terms

Smad1 Protein

Below are MeSH descriptors whose meaning is more general than "Smad1 Protein".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Adaptor Proteins, Signal Transducing [D12.644.360.024]
Smad Proteins [D12.644.360.024.334]
Smad Proteins, Receptor-Regulated [D12.644.360.024.334.500]
Smad1 Protein [D12.644.360.024.334.500.100]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Adaptor Proteins, Signal Transducing [D12.776.157.057]
Smad Proteins [D12.776.157.057.170]
Smad Proteins, Receptor-Regulated [D12.776.157.057.170.500]
Smad1 Protein [D12.776.157.057.170.500.100]
DNA-Binding Proteins [D12.776.260]
Smad Proteins [D12.776.260.713]
Smad Proteins, Receptor-Regulated [D12.776.260.713.500]
Smad1 Protein [D12.776.260.713.500.100]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Adaptor Proteins, Signal Transducing [D12.776.476.024]
Smad Proteins [D12.776.476.024.417]
Smad Proteins, Receptor-Regulated [D12.776.476.024.417.500]
Smad1 Protein [D12.776.476.024.417.500.100]
Phosphoproteins [D12.776.744]
Smad Proteins, Receptor-Regulated [D12.776.744.741]
Smad1 Protein [D12.776.744.741.500]
Transcription Factors [D12.776.930]
Smad Proteins [D12.776.930.806]
Smad Proteins, Receptor-Regulated [D12.776.930.806.500]
Smad1 Protein [D12.776.930.806.500.100]

Below are MeSH descriptors whose meaning is related to "Smad1 Protein".

Below are MeSH descriptors whose meaning is more specific than "Smad1 Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Smad1 Protein" by people in Harvard Catalyst Profiles by year, and whether "Smad1 Protein" was a major or minor topic of these publication.

Bar chart showing 51 publications over 20 distinct years, with a maximum of 5 publications in 2005 and 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	2	2
2000	0	1	1
2001	0	3	3
2003	0	1	1
2004	0	3	3
2005	0	5	5
2006	3	0	3
2007	1	0	1
2008	2	0	2
2009	1	2	3
2010	0	1	1
2011	1	1	2
2012	0	4	4
2013	1	1	2
2014	2	1	3
2016	1	3	4
2017	2	3	5
2018	0	2	2
2019	1	2	3
2020	0	1	1

Below are the most recent publications written about "Smad1 Protein" by people in Profiles.

Common variants in signaling transcription-factor-binding sites drive phenotypic variability in red blood cell traits. Nat Genet. 2020 12; 52(12):1333-1345.

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Ablation of Hepatocyte Smad1, Smad5, and Smad8 Causes Severe Tissue Iron Loading and Liver Fibrosis in Mice. Hepatology. 2019 12; 70(6):1986-2002.

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Reactivation of a developmental Bmp2 signaling center is required for therapeutic control of the murine periosteal niche. Elife. 2019 02 08; 8.

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Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer. Breast Cancer Res. 2019 01 23; 21(1):11.

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Antiviral activity of bone morphogenetic proteins and activins. Nat Microbiol. 2019 02; 4(2):339-351.

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Bone Morphogenetic Protein 9 Reduces Cardiac Fibrosis and Improves Cardiac Function in Heart Failure. Circulation. 2018 07 31; 138(5):513-526.

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Osteogenic and Chondrogenic Master Genes Expression Is Dependent on the Kir2.1 Potassium Channel Through the Bone Morphogenetic Protein Pathway. J Bone Miner Res. 2018 10; 33(10):1826-1841.

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Loss of the Hematopoietic Stem Cell Factor GATA2 in the Osteogenic Lineage Impairs Trabecularization and Mechanical Strength of Bone. Mol Cell Biol. 2018 06 15; 38(12).

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Temporal Layering of Signaling Effectors Drives Chromatin Remodeling during Hair Follicle Stem Cell Lineage Progression. Cell Stem Cell. 2018 03 01; 22(3):398-413.e7.

View in: PubMed
Inference of differentiation time for single cell transcriptomes using cell population reference data. Nat Commun. 2017 11 30; 8(1):1856.

View in: PubMed

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