Smad5 Protein

"Smad5 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A receptor-regulated smad protein that undergoes PHOSPHORYLATION by BONE MORPHOGENETIC PROTEIN RECEPTORS. It regulates BONE MORPHOGENETIC PROTEIN signaling and is essential for PHYSIOLOGICAL ANGIOGENESIS.

Descriptor ID

D051902

MeSH Number(s)

D12.644.360.024.334.500.500

D12.776.157.057.170.500.500

D12.776.260.713.500.500

D12.776.476.024.417.500.500

D12.776.744.741.937

D12.776.930.806.500.500

Concept/Terms

Smad5 Protein

Below are MeSH descriptors whose meaning is more general than "Smad5 Protein".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Adaptor Proteins, Signal Transducing [D12.644.360.024]
Smad Proteins [D12.644.360.024.334]
Smad Proteins, Receptor-Regulated [D12.644.360.024.334.500]
Smad5 Protein [D12.644.360.024.334.500.500]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Adaptor Proteins, Signal Transducing [D12.776.157.057]
Smad Proteins [D12.776.157.057.170]
Smad Proteins, Receptor-Regulated [D12.776.157.057.170.500]
Smad5 Protein [D12.776.157.057.170.500.500]
DNA-Binding Proteins [D12.776.260]
Smad Proteins [D12.776.260.713]
Smad Proteins, Receptor-Regulated [D12.776.260.713.500]
Smad5 Protein [D12.776.260.713.500.500]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Adaptor Proteins, Signal Transducing [D12.776.476.024]
Smad Proteins [D12.776.476.024.417]
Smad Proteins, Receptor-Regulated [D12.776.476.024.417.500]
Smad5 Protein [D12.776.476.024.417.500.500]
Phosphoproteins [D12.776.744]
Smad Proteins, Receptor-Regulated [D12.776.744.741]
Smad5 Protein [D12.776.744.741.937]
Transcription Factors [D12.776.930]
Smad Proteins [D12.776.930.806]
Smad Proteins, Receptor-Regulated [D12.776.930.806.500]
Smad5 Protein [D12.776.930.806.500.500]

Below are MeSH descriptors whose meaning is related to "Smad5 Protein".

Below are MeSH descriptors whose meaning is more specific than "Smad5 Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Smad5 Protein" by people in Harvard Catalyst Profiles by year, and whether "Smad5 Protein" was a major or minor topic of these publication.

Bar chart showing 21 publications over 13 distinct years, with a maximum of 4 publications in 2017

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2000	0	2	2
2002	0	1	1
2003	0	1	1
2005	0	2	2
2008	1	0	1
2009	0	1	1
2011	1	0	1
2012	0	2	2
2013	0	1	1
2014	0	1	1
2016	0	3	3
2017	2	2	4
2019	1	0	1

Below are the most recent publications written about "Smad5 Protein" by people in Profiles.

Ablation of Hepatocyte Smad1, Smad5, and Smad8 Causes Severe Tissue Iron Loading and Liver Fibrosis in Mice. Hepatology. 2019 12; 70(6):1986-2002.

View in: PubMed
Loss of the Hematopoietic Stem Cell Factor GATA2 in the Osteogenic Lineage Impairs Trabecularization and Mechanical Strength of Bone. Mol Cell Biol. 2018 06 15; 38(12).

View in: PubMed
Bone morphogenetic protein 2 controls iron homeostasis in mice independent of Bmp6. Am J Hematol. 2017 Nov; 92(11):1204-1213.

View in: PubMed
Transforming growth factor-ß stimulates Smad1/5 signaling in pulmonary artery smooth muscle cells and fibroblasts of the newborn mouse through ALK1. Am J Physiol Lung Cell Mol Physiol. 2017 Sep 01; 313(3):L615-L627.

View in: PubMed
Metformin inhibits ALK1-mediated angiogenesis via activation of AMPK. Oncotarget. 2017 May 16; 8(20):32794-32806.

View in: PubMed
Smad1/5 is required for erythropoietin-mediated suppression of hepcidin in mice. Blood. 2017 07 06; 130(1):73-83.

View in: PubMed
Physiological exercise loading suppresses post-traumatic osteoarthritis progression via an increase in bone morphogenetic proteins expression in an experimental rat knee model. Osteoarthritis Cartilage. 2017 06; 25(6):964-975.

View in: PubMed
Characterization of Cells Isolated from Genetic and Trauma-Induced Heterotopic Ossification. PLoS One. 2016; 11(8):e0156253.

View in: PubMed
Activin B Induces Noncanonical SMAD1/5/8 Signaling via BMP Type I Receptors in Hepatocytes: Evidence for a Role in Hepcidin Induction by Inflammation in Male Mice. Endocrinology. 2016 Mar; 157(3):1146-62.

View in: PubMed
BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells. Stem Cell Reports. 2016 Jan 12; 6(1):85-94.

View in: PubMed

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