beta-Transducin Repeat-Containing Proteins
"beta-Transducin Repeat-Containing Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of F-box domain proteins that contain sequences that are homologous to the beta subunit of transducin (BETA-TRANSDUCIN). They play an important role in the protein degradation pathway by becoming components of SKP CULLIN F-BOX PROTEIN LIGASES, which selectively act on a subset of proteins including beta-catenin and IkappaBbeta.
Concept/Terms
beta-Transducin Repeat-Containing Proteins- beta-Transducin Repeat-Containing Proteins
- Repeat-Containing Proteins, beta-Transducin
- beta Transducin Repeat Containing Proteins
- betaTrCP
- beta-Transducin Repeat-Containing Protein
- Protein, beta-Transducin Repeat-Containing
- Repeat-Containing Protein, beta-Transducin
- beta Transducin Repeat Containing Protein
- beta-TrCP
- beta TrCP
Below are MeSH descriptors whose meaning is more general than "beta-Transducin Repeat-Containing Proteins".
Below are MeSH descriptors whose meaning is more specific than "beta-Transducin Repeat-Containing Proteins".
This graph shows the total number of publications written about "beta-Transducin Repeat-Containing Proteins" by people in Harvard Catalyst Profiles by year, and whether "beta-Transducin Repeat-Containing Proteins" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 1 | 3 |
| 2013 | 2 | 1 | 3 |
| 2014 | 0 | 2 | 2 |
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 1 | 0 | 1 |
| 2023 | 1 | 0 | 1 |
Below are the most recent publications written about "beta-Transducin Repeat-Containing Proteins" by people in Profiles.
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Sequence variants in DLX5, HOXD13 and 445?kb-microduplication surrounding BTRC cause split-hand/foot malformation in three different families. Clin Genet. 2024 01; 105(1):109-111.
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Small-molecule modulators of INAVA cytosolic condensate and cell-cell junction assemblies. J Cell Biol. 2021 09 06; 220(9).
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Lipin-2 degradation elicits a proinflammatory gene signature in macrophages. Biochem Biophys Res Commun. 2020 04 02; 524(2):477-483.
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SCFß-TrCP ubiquitinates CHK1 in an AMPK-dependent manner in response to glucose deprivation. Mol Oncol. 2019 02; 13(2):307-321.
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The tuberous sclerosis complex subunit TBC1D7 is stabilized by Akt phosphorylation-mediated 14-3-3 binding. J Biol Chem. 2018 10 19; 293(42):16142-16159.
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ß-TrCP-dependent degradation of ASK1 suppresses the induction of the apoptotic response by oxidative stress. Biochim Biophys Acta Gen Subj. 2018 10; 1862(10):2271-2280.
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SCFß-TRCP E3 ubiquitin ligase targets the tumor suppressor ZNRF3 for ubiquitination and degradation. Protein Cell. 2018 10; 9(10):879-889.
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Stability of Wake-Sleep Cycles Requires Robust Degradation of the PERIOD Protein. Curr Biol. 2017 Nov 20; 27(22):3454-3467.e8.
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ß-TrCP1 Is a Vacillatory Regulator of Wnt Signaling. Cell Chem Biol. 2017 Aug 17; 24(8):944-957.e7.
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A new layer of degradation mechanism for PR-Set7/Set8 during cell cycle. Cell Cycle. 2016 Nov 16; 15(22):3042-3047.