Receptor, Melanocortin, Type 1
"Receptor, Melanocortin, Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A melanocortin receptor subtype found primarily in MELANOCYTES. It shows specificity for ALPHA-MSH and ADRENOCORTICOTROPIC HORMONE. Loss of function mutations of the type 1 melanocortin receptor account for the majority of red hair and fair skin recessive traits in human.
MeSH Number(s)
D12.776.543.750.100.430.500
D12.776.543.750.720.600.285.500.500
D12.776.543.750.750.555.285.500.500
D12.776.543.750.750.660.285.500.500
Concept/Terms
Receptor, Melanocortin, Type 1- Receptor, Melanocortin, Type 1
- Melanocortin Receptor 1
- Receptor 1, Melanocortin
- Melanocyte Melanocortin Receptor
- Melanocortin Receptor, Melanocyte
- Receptor, Melanocyte Melanocortin
- Receptor, Melanocortin-1
- Receptor, Melanocortin 1
- MC1 Receptor
- Receptor, MC1
- Melanocortin-1 Receptor
- Melanocortin 1 Receptor
Below are MeSH descriptors whose meaning is more general than "Receptor, Melanocortin, Type 1".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Melanocortin [D12.776.543.750.100.430]
- Receptor, Melanocortin, Type 1 [D12.776.543.750.100.430.500]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Corticotropin [D12.776.543.750.720.600.285]
- Receptors, Melanocortin [D12.776.543.750.720.600.285.500]
- Receptor, Melanocortin, Type 1 [D12.776.543.750.720.600.285.500.500]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Corticotropin [D12.776.543.750.750.555.285]
- Receptors, Melanocortin [D12.776.543.750.750.555.285.500]
- Receptor, Melanocortin, Type 1 [D12.776.543.750.750.555.285.500.500]
- Receptors, Pituitary Hormone [D12.776.543.750.750.660]
- Receptors, Corticotropin [D12.776.543.750.750.660.285]
- Receptors, Melanocortin [D12.776.543.750.750.660.285.500]
- Receptor, Melanocortin, Type 1 [D12.776.543.750.750.660.285.500.500]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Melanocortin, Type 1".
This graph shows the total number of publications written about "Receptor, Melanocortin, Type 1" by people in Harvard Catalyst Profiles by year, and whether "Receptor, Melanocortin, Type 1" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
2003 | 0 | 1 | 1 |
2004 | 1 | 0 | 1 |
2005 | 2 | 0 | 2 |
2006 | 4 | 0 | 4 |
2007 | 1 | 1 | 2 |
2008 | 1 | 0 | 1 |
2009 | 2 | 4 | 6 |
2010 | 1 | 1 | 2 |
2011 | 0 | 3 | 3 |
2012 | 0 | 1 | 1 |
2013 | 2 | 0 | 2 |
2014 | 1 | 1 | 2 |
2015 | 5 | 0 | 5 |
2016 | 2 | 1 | 3 |
2017 | 1 | 1 | 2 |
2018 | 2 | 1 | 3 |
2020 | 1 | 1 | 2 |
2021 | 0 | 3 | 3 |
2022 | 1 | 0 | 1 |
2023 | 0 | 1 | 1 |
Below are the most recent publications written about "Receptor, Melanocortin, Type 1" by people in Profiles.
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Peripheral MC1R Activation Modulates Immune Responses and is Neuroprotective in a Mouse Model of Parkinson's Disease. J Neuroimmune Pharmacol. 2023 12; 18(4):704-717.
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Melanocortin 1 receptor activation protects against alpha-synuclein pathologies in models of Parkinson's disease. Mol Neurodegener. 2022 02 23; 17(1):16.
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The Neuropeptide Alpha-Melanocyte-Stimulating Hormone Is Critical for Corneal Endothelial Cell Protection and Graft Survival after Transplantation. Am J Pathol. 2022 02; 192(2):270-280.
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Melanocytes determine angiogenesis gene expression across human tissues. PLoS One. 2021; 16(5):e0251121.
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Reduced MC4R signaling alters nociceptive thresholds associated with red hair. Sci Adv. 2021 04; 7(14).
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Melanocortin 1 receptor is dispensable for acute stress induced hair graying in mice. Exp Dermatol. 2021 04; 30(4):572-577.
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Red Hair Color Is Associated with Elevated CRP Levels among US Women. J Invest Dermatol. 2021 05; 141(5):1342-1344.
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CDKN2A/CDK4 Status in Greek Patients with Familial Melanoma and Association with Clinico-epidemiological Parameters. Acta Derm Venereol. 2018 Oct 10; 98(9):862-866.
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MC1R gene polymorphisms are associated with dysfunctional immune responses and wound infection after burn injury. J Surg Res. 2018 11; 231:448-452.
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Hierarchical modeling of melanocortin 1 receptor variants with skin cancer risk. Genet Epidemiol. 2018 09; 42(6):571-586.