Receptor, Melanocortin, Type 4
"Receptor, Melanocortin, Type 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A melanocortin receptor subtype found primarily in BRAIN. It shows specificity for ALPHA-MSH; BETA-MSH and ADRENOCORTICOTROPIC HORMONE.
MeSH Number(s)
D12.776.543.750.100.430.937
D12.776.543.750.720.600.285.500.937
D12.776.543.750.750.555.285.500.937
D12.776.543.750.750.660.285.500.937
Concept/Terms
Receptor, Melanocortin, Type 4- Receptor, Melanocortin, Type 4
- Melanocortin Receptor 4
- Receptor 4, Melanocortin
- Receptor, Melanocortin-4
- Melanocortin 4 Receptor
- Receptor, Melanocortin 4
- Melanocortin-4 Receptor
- MC4 Receptor
- Receptor, MC4
Below are MeSH descriptors whose meaning is more general than "Receptor, Melanocortin, Type 4".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.100]
- Receptors, Melanocortin [D12.776.543.750.100.430]
- Receptor, Melanocortin, Type 4 [D12.776.543.750.100.430.937]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Neuropeptide [D12.776.543.750.720.600]
- Receptors, Corticotropin [D12.776.543.750.720.600.285]
- Receptors, Melanocortin [D12.776.543.750.720.600.285.500]
- Receptor, Melanocortin, Type 4 [D12.776.543.750.720.600.285.500.937]
- Receptors, Peptide [D12.776.543.750.750]
- Receptors, Neuropeptide [D12.776.543.750.750.555]
- Receptors, Corticotropin [D12.776.543.750.750.555.285]
- Receptors, Melanocortin [D12.776.543.750.750.555.285.500]
- Receptor, Melanocortin, Type 4 [D12.776.543.750.750.555.285.500.937]
- Receptors, Pituitary Hormone [D12.776.543.750.750.660]
- Receptors, Corticotropin [D12.776.543.750.750.660.285]
- Receptors, Melanocortin [D12.776.543.750.750.660.285.500]
- Receptor, Melanocortin, Type 4 [D12.776.543.750.750.660.285.500.937]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Melanocortin, Type 4".
This graph shows the total number of publications written about "Receptor, Melanocortin, Type 4" by people in Harvard Catalyst Profiles by year, and whether "Receptor, Melanocortin, Type 4" was a major or minor topic of these publication.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
---|
1999 | 0 | 1 | 1 |
2001 | 0 | 2 | 2 |
2002 | 0 | 1 | 1 |
2003 | 2 | 6 | 8 |
2004 | 1 | 0 | 1 |
2005 | 3 | 1 | 4 |
2006 | 1 | 1 | 2 |
2007 | 0 | 1 | 1 |
2008 | 3 | 0 | 3 |
2009 | 0 | 2 | 2 |
2010 | 2 | 1 | 3 |
2011 | 3 | 2 | 5 |
2012 | 4 | 0 | 4 |
2013 | 6 | 2 | 8 |
2014 | 2 | 1 | 3 |
2015 | 2 | 1 | 3 |
2016 | 5 | 0 | 5 |
2017 | 4 | 0 | 4 |
2018 | 2 | 0 | 2 |
2019 | 4 | 3 | 7 |
2020 | 2 | 0 | 2 |
2021 | 2 | 3 | 5 |
2023 | 1 | 1 | 2 |
Below are the most recent publications written about "Receptor, Melanocortin, Type 4" by people in Profiles.
-
Influence of polymorphisms in IRS1, IRS2, MC3R, and MC4R on metabolic and inflammatory status and food intake in Brazilian adults: An exploratory pilot study. Nutr Res. 2023 Nov; 119:21-32.
-
Prefrontal cortex melanocortin 4 receptors (MC4R) mediate food intake behavior in male mice. Physiol Behav. 2023 10 01; 269:114280.
-
An Association between Diet and MC4R Genetic Polymorphism, in Relation to Obesity and Metabolic Parameters-A Cross Sectional Population-Based Study. Int J Mol Sci. 2021 Nov 07; 22(21).
-
Oestrogen engages brain MC4R signalling to drive physical activity in female mice. Nature. 2021 11; 599(7883):131-135.
-
Cardiac Phenotype and Tissue Sodium Content in Adolescents With Defects in the Melanocortin System. J Clin Endocrinol Metab. 2021 08 18; 106(9):2606-2616.
-
Lipocalin 2 mediates appetite suppression during pancreatic cancer cachexia. Nat Commun. 2021 04 06; 12(1):2057.
-
Reduced MC4R signaling alters nociceptive thresholds associated with red hair. Sci Adv. 2021 04; 7(14).
-
Association of MC4R (rs17782313) gene polymorphism with obesity measures in Western India. Diabetes Metab Syndr. 2021 May-Jun; 15(3):661-665.
-
The First Genome-Wide Association Study for Type 2 Diabetes in Youth: The Progress in Diabetes Genetics in Youth (ProDiGY) Consortium. Diabetes. 2021 04; 70(4):996-1005.
-
Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials. Lancet Diabetes Endocrinol. 2020 12; 8(12):960-970.