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profileRNA-Binding Protein FUS

"RNA-Binding Protein FUS" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

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A multifunctional heterogeneous-nuclear ribonucleoprotein that may play a role in homologous DNA pairing and recombination. The N-terminal portion of protein is a potent transcriptional activator, while the C terminus is required for RNA binding. The name FUS refers to the fact that genetic recombination events result in fusion oncogene proteins (ONCOGENE PROTEINS, FUSION) that contain the N-terminal region of this protein. These fusion proteins have been found in myxoid liposarcoma (LIPOSARCOMA, MYXOID) and acute myeloid leukemia.


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This graph shows the total number of publications written about "RNA-Binding Protein FUS" by people in Harvard Catalyst Profiles by year, and whether "RNA-Binding Protein FUS" was a major or minor topic of these publication.
Bar chart showing 45 publications over 16 distinct years, with a maximum of 7 publications in 2012
To see the data from this visualization as text, click here.