Telomere-Binding Proteins

"Telomere-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins that specifically bind to TELOMERES. Proteins in this class include those that perform functions such as telomere capping, telomere maintenance and telomere stabilization.

Descriptor ID

D034501

MeSH Number(s)

D12.776.260.735

D12.776.660.235.700

Concept/Terms

Telomere-Binding Proteins

Telomere Repeat Binding Proteins

Telomer-Binding Protein, alpha-Subunit

Telomer-Binding Protein, beta-Subunit

Double-Stranded Telomere-Binding Proteins

Single-Stranded Telomere-Binding Proteins

Below are MeSH descriptors whose meaning is more general than "Telomere-Binding Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Telomere-Binding Proteins [D12.776.260.735]
Nuclear Proteins [D12.776.660]
Chromosomal Proteins, Non-Histone [D12.776.660.235]
Telomere-Binding Proteins [D12.776.660.235.700]

Below are MeSH descriptors whose meaning is related to "Telomere-Binding Proteins".

Below are MeSH descriptors whose meaning is more specific than "Telomere-Binding Proteins".

Telomere-Binding Proteins
Heterogeneous-Nuclear Ribonucleoprotein Group A-B
Telomeric Repeat Binding Protein 1
Telomeric Repeat Binding Protein 2

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Telomere-Binding Proteins" by people in Harvard Catalyst Profiles by year, and whether "Telomere-Binding Proteins" was a major or minor topic of these publication.

Bar chart showing 80 publications over 19 distinct years, with a maximum of 8 publications in 2017 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2004	1	2	3
2006	0	3	3
2007	1	0	1
2008	1	0	1
2009	1	1	2
2010	2	0	2
2011	0	2	2
2012	4	3	7
2013	4	2	6
2014	3	2	5
2015	2	1	3
2016	4	1	5
2017	3	5	8
2018	2	5	7
2019	3	3	6
2020	2	3	5
2021	4	4	8
2022	1	3	4
2023	0	2	2

Below are the most recent publications written about "Telomere-Binding Proteins" by people in Profiles.

Pot1b -/- tumors activate G-quadruplex-induced DNA damage to promote telomere hyper-elongation. Nucleic Acids Res. 2023 09 22; 51(17):9227-9247.

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Familial Clonal Hematopoiesis in a Long Telomere Syndrome. N Engl J Med. 2023 Jun 29; 388(26):2422-2433.

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TPP1 promoter mutations cooperate with TERT promoter mutations to lengthen telomeres in melanoma. Science. 2022 Nov 11; 378(6620):664-668.

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Vectorial folding of telomere overhang promotes higher accessibility. Nucleic Acids Res. 2022 06 24; 50(11):6271-6283.

View in: PubMed
Helicase mediated vectorial folding of telomere G-quadruplex. Methods Enzymol. 2022; 672:283-297.

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Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region. Elife. 2022 04 13; 11.

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TRF2 promotes dynamic and stepwise looping of POT1 bound telomeric overhang. Nucleic Acids Res. 2021 12 02; 49(21):12377-12393.

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Distinct functions of POT1 proteins contribute to the regulation of telomerase recruitment to telomeres. Nat Commun. 2021 09 17; 12(1):5514.

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Somatic reversion impacts myelodysplastic syndromes and acute myeloid leukemia evolution in the short telomere disorders. J Clin Invest. 2021 09 15; 131(18).

View in: PubMed
Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia. Nat Commun. 2021 09 13; 12(1):5395.

View in: PubMed

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