Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Proto-Oncogene Proteins c-abl

"Proto-Oncogene Proteins c-abl" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Non-receptor tyrosine kinases encoded by the C-ABL GENES. They are distributed in both the cytoplasm and the nucleus. c-Abl plays a role in normal HEMATOPOIESIS especially of the myeloid lineage. Oncogenic transformation of c-abl arises when specific N-terminal amino acids are deleted, releasing the kinase from negative regulation.


This graph shows the total number of publications written about "Proto-Oncogene Proteins c-abl" by people in Harvard Catalyst Profiles by year, and whether "Proto-Oncogene Proteins c-abl" was a major or minor topic of these publication.
Bar chart showing 111 publications over 28 distinct years, with a maximum of 9 publications in 2000
To see the data from this visualization as text, click here.
Related Networks
People
Explore
_
Similar Concepts
_
Top Journals 
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.