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Pregnancy-Associated Plasma Protein-A

"Pregnancy-Associated Plasma Protein-A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

A product of the PLACENTA, and DECIDUA, secreted into the maternal circulation during PREGNANCY. It has been identified as an IGF binding protein (IGFBP)-4 protease that proteolyzes IGFBP-4 and thus increases IGF bioavailability. It is found also in human FIBROBLASTS, ovarian FOLLICULAR FLUID, and GRANULOSA CELLS. The enzyme is a heterotetramer of about 500-kDa.


This graph shows the total number of publications written about "Pregnancy-Associated Plasma Protein-A" by people in Harvard Catalyst Profiles by year, and whether "Pregnancy-Associated Plasma Protein-A" was a major or minor topic of these publication.
Bar chart showing 19 publications over 11 distinct years, with a maximum of 4 publications in 2019
To see the data from this visualization as text, click here.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.