Placental Lactogen

"Placental Lactogen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A polypeptide hormone of approximately 25 kDa that is produced by the SYNCYTIOTROPHOBLASTS of the PLACENTA, also known as chorionic somatomammotropin. It has both GROWTH HORMONE and PROLACTIN activities on growth, lactation, and luteal steroid production. In women, placental lactogen secretion begins soon after implantation and increases to 1 g or more a day in late pregnancy. Placental lactogen is also an insulin antagonist.

Descriptor ID

D010928

MeSH Number(s)

D06.472.699.649.692

D12.644.548.726.692

D12.776.780.650

Concept/Terms

Placental Lactogen

Human Placental Lactogen

Below are MeSH descriptors whose meaning is more general than "Placental Lactogen".

Chemicals and Drugs [D]
Hormones, Hormone Substitutes, and Hormone Antagonists [D06]
Hormones [D06.472]
Peptide Hormones [D06.472.699]
Placental Hormones [D06.472.699.649]
Placental Lactogen [D06.472.699.649.692]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Peptide Hormones [D12.644.548]
Placental Hormones [D12.644.548.726]
Placental Lactogen [D12.644.548.726.692]
Proteins [D12.776]
Pregnancy Proteins [D12.776.780]
Placental Lactogen [D12.776.780.650]

Below are MeSH descriptors whose meaning is related to "Placental Lactogen".

Below are MeSH descriptors whose meaning is more specific than "Placental Lactogen".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Placental Lactogen" by people in Harvard Catalyst Profiles by year, and whether "Placental Lactogen" was a major or minor topic of these publication.

Bar chart showing 6 publications over 4 distinct years, with a maximum of 3 publications in 1997

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	0	1
1995	1	0	1
1997	1	2	3
2013	0	1	1

Below are the most recent publications written about "Placental Lactogen" by people in Profiles.

Early growth and development of later life metabolic disorders. Nestle Nutr Inst Workshop Ser. 2013; 71:75-84.

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Identification of functional CCAAT/enhancer-binding protein and Ets protein binding sites in the human chorionic somatomammotropin enhancer sequences. J Mol Endocrinol. 2011 Oct; 47(2):179-93.

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Hypoxia inhibits differentiation of lineage-specific Rcho-1 trophoblast giant cells. Biol Reprod. 2006 Jun; 74(6):1041-50.

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Hepatocyte nuclear factor-3alpha binding at P sequences of the human growth hormone locus is associated with pituitary repressor function. Mol Endocrinol. 2006 Mar; 20(3):598-607.

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Binding of AP-2 and ETS-domain family members is associated with enhancer activity in the hypersensitive site III region of the human growth hormone/chorionic somatomammotropin locus. Mol Endocrinol. 2004 Mar; 18(3):574-87.

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Detection of placental growth hormone variant and chorionic somatomammotropin-L RNA expression in normal and diabetic pregnancy by reverse transcriptase-polymerase chain reaction. Mol Cell Endocrinol. 1999 Nov 25; 157(1-2):131-42.

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Heart and extra-embryonic mesodermal defects in mouse embryos lacking the bHLH transcription factor Hand1. Nat Genet. 1998 Mar; 18(3):266-70.

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Recognition of porcine growth hormone by a panel of monoclonal antibodies. Hybridoma. 1997 Aug; 16(4):371-9.

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Regulation of interleukin (IL)-1alpha, IL-1beta, and IL-6 expression by growth hormone and prolactin in bovine thymic stromal cells. Mol Cell Endocrinol. 1997 Apr 04; 128(1-2):117-27.

View in: PubMed
GATA-2 and GATA-3 regulate trophoblast-specific gene expression in vivo. Development. 1997 Feb; 124(4):907-14.

View in: PubMed

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