Ankyrins

"Ankyrins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A family of membrane-associated proteins responsible for the attachment of the cytoskeleton. Erythrocyte-related isoforms of ankyrin attach the SPECTRIN cytoskeleton to a transmembrane protein (ANION EXCHANGE PROTEIN 1, ERYTHROCYTE) in the erythrocyte plasma membrane. Brain-related isoforms of ankyrin also exist.

Descriptor ID

D017487

MeSH Number(s)

D12.776.124.080

D12.776.543.080

Concept/Terms

Ankyrins

Below are MeSH descriptors whose meaning is more general than "Ankyrins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Blood Proteins [D12.776.124]
Ankyrins [D12.776.124.080]
Membrane Proteins [D12.776.543]
Ankyrins [D12.776.543.080]

Below are MeSH descriptors whose meaning is related to "Ankyrins".

Below are MeSH descriptors whose meaning is more specific than "Ankyrins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Ankyrins" by people in Harvard Catalyst Profiles by year, and whether "Ankyrins" was a major or minor topic of these publication.

Bar chart showing 68 publications over 26 distinct years, with a maximum of 6 publications in 1995

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1994	1	1	2
1995	3	3	6
1996	1	2	3
1997	3	1	4
1998	2	2	4
2000	1	0	1
2002	2	2	4
2003	1	1	2
2005	1	1	2
2007	1	1	2
2008	1	1	2
2009	0	2	2
2010	1	0	1
2011	0	2	2
2012	4	1	5
2013	3	1	4
2014	2	1	3
2015	0	2	2
2016	0	1	1
2017	1	1	2
2018	1	4	5
2019	1	1	2
2020	0	2	2
2021	2	1	3
2022	0	1	1
2023	0	1	1

Below are the most recent publications written about "Ankyrins" by people in Profiles.

a-Synuclein Promotes Neuronal Dysfunction and Death by Disrupting the Binding of Ankyrin to ß-Spectrin. J Neurosci. 2023 03 01; 43(9):1614-1626.

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Lithium rescues dendritic abnormalities in Ank3 deficiency models through the synergic effects of GSK3ß and cyclic AMP signaling pathways. Neuropsychopharmacology. 2023 06; 48(7):1000-1010.

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Randomized, double-blind, placebo-controlled trial of ISC 17536, an oral inhibitor of transient receptor potential ankyrin 1, in patients with painful diabetic peripheral neuropathy: impact of preserved small nerve fiber function. Pain. 2022 06 01; 163(6):e738-e747.

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Ankyrin G organizes membrane components to promote coupling of cell mechanics and glucose uptake. Nat Cell Biol. 2021 05; 23(5):457-466.

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Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes. Nat Commun. 2021 01 08; 12(1):189.

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In vivo Perturb-Seq reveals neuronal and glial abnormalities associated with autism risk genes. Science. 2020 11 27; 370(6520).

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Identification of type 2 diabetes loci in 433,540 East Asian individuals. Nature. 2020 06; 582(7811):240-245.

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Neuroprotective Peptide NAPVSIPQ Antagonizes Ethanol Inhibition of L1 Adhesion by Promoting the Dissociation of L1 and Ankyrin-G. Biol Psychiatry. 2020 04 01; 87(7):656-665.

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Beyond evidence-based treatment of bipolar disorder: Rational pragmatic approaches to management. Bipolar Disord. 2019 11; 21(7):650-659.

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Disruption of the psychiatric risk gene Ankyrin 3 enhances microtubule dynamics through GSK3/CRMP2 signaling. Transl Psychiatry. 2018 07 25; 8(1):135.

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